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Heather ShearerPostdoctoral Fellow

 PhD(Otago)

Email heather.shearer@otago.ac.nz
Tel +64 3 378 6159

Research interests

Postdoctoral Fellow Heather Shearer is investigating the mechanisms underlying S. pneumoniae resistance to oxidants.

She recently completed her PhD project on the sensitivity of S. pneumoniae to oxidative stress, and how we can improve the killing of these pathogenic bacteria by our immune systems.

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Publications

Shearer, H. L. (2022). Sensitising Streptococcus pneumoniae to oxidative stress (PhD). University of Otago, Dunedin, New Zealand. Retrieved from http://hdl.handle.net/10523/12770

Shearer, H. L., Kaldor, C. D., Hua, H., Kettle, A. J., Parker, H. A., & Hampton, M. B. (2022). Resistance of Streptococcus pneumoniae to hypothiocyanous acid generated by host peroxidases. Infection & Immunity. Advance online publication. doi: 10.1128/iai.00530-21

Shearer, H. L., Paton, J. C., Hampton, M. B., & Dickerhof, N. (2022). Glutathione utilization protects Streptococcus pneumoniae against lactoperoxidase-derived hypothiocyanous acid. Free Radical Biology & Medicine, 179, 24-33. doi: 10.1016/j.freeradbiomed.2021.12.261

Shearer, H. L., Hampton, M. B., & Dickerhof, N. (2022). Bactericidal activity of the oxidants derived from mammilian heme peroxidases. In C. L. Hawkins & W. M. Nauseef (Eds.), Mammalian heme peroxidases: Diverse roles in health and disease. (pp. 171-188). Boca Raton, FL: CRC Press. doi: 10.1201/9781003212287

Shearer, H. L., Parker, H. A., Paton, J., Camilli, A., Pace, P. E., Dickerhof, N., & Hampton, M. B. (2021). Sensitising Streptococcus pneumoniae to oxidative stress. Proceedings of the 16th Congress of the Federation of Asian & Oceanic Biochemists & Molecular Biologists (FAOBMB). (pp. 145). Retrieved from https://www.faobmb2021.org