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Teagan HoskinPostdoctoral Fellow

BBiomedSc(Hons), PhD (Otago)

Email teagan.hoskin@otago.ac.nz
Tel +64 3 364 0566

Research interests

Dr Teagan Hoskin is investigating oxidative post-translational modifications of calprotectin during inflammation.

Dr Hoskin completed her PhD in 2018 under the supervision of Professor Tony Kettle, Dr Nina Dickerhof, Professor Richard Gearry and Professor Andrew Day.

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Publications

Hoskin, T. S., Crowther, J. M., Cheung, J., Epton, M. J., Sly, P. D., Elder, P. A., … Kettle, A. J., & Dickerhof, N. (2019). Oxidative cross-linking of calprotectin occurs in vivo, altering its structure and susceptibility to proteolysis. Redox Biology. Advance online publication. doi: 10.1016/j.redox.2019.101202

Hoskin, T. S. (2018). Oxidative post-transitional modifications of calprotectin during inflammation (PhD). University of Otago, Dunedin, New Zealand. Retrieved from http://hdl.handle.net/10523/8366

Dickerhof, N., Pearson, J. F., Hoskin, T. S., Berry, L. J., Turner, R., Sly, P. D., Kettle, A. J., on behalf of AREST CF. (2017). Oxidative stress in early cystic fibrosis lung disease is exacerbated by airway glutathione deficiency. Free Radical Biology & Medicine, 113, 236-243. doi: 10.1016/j.freeradbiomed.2017.09.028

Dickerhof, N., Pearson, J. F., Hoskin, T. S., Sly, P. D., & Kettle, A. J. (2017, August). Myeloperoxidase is associated with bronchiectasis in children with cystic fibrosis. Verbal presentation at the 10th International Human Peroxidase Meeting, Breckenridge, USA.

Hoskin, T. S., Dickerhof, N., Hampton, M. B., & Kettle, A. J. (2017, July). Calprotectin is sensitive to oxidants generated by myeloperoxidase. Verbal presentation at the New Zealand Branch of the Australasian Society for Immunology (NZ ASI) Annual Scientific Meeting, Christchurch, New Zealand.

Journal - Research Article

Hoskin, T. S., Crowther, J. M., Cheung, J., Epton, M. J., Sly, P. D., Elder, P. A., … Kettle, A. J., & Dickerhof, N. (2019). Oxidative cross-linking of calprotectin occurs in vivo, altering its structure and susceptibility to proteolysis. Redox Biology. Advance online publication. doi: 10.1016/j.redox.2019.101202

Dickerhof, N., Pearson, J. F., Hoskin, T. S., Berry, L. J., Turner, R., Sly, P. D., Kettle, A. J., on behalf of AREST CF. (2017). Oxidative stress in early cystic fibrosis lung disease is exacerbated by airway glutathione deficiency. Free Radical Biology & Medicine, 113, 236-243. doi: 10.1016/j.freeradbiomed.2017.09.028

Falvey, J. D., Hoskin, T., Meijer, B., Ashcroft, A., Walmsley, R., Day, A. S., & Gearry, R. B. (2015). Disease activity assessment in IBD: Clinical indices and biomarkers fail to predict endoscopic remission. Inflammatory Bowel Diseases, 21, 824-831. doi: 10.1097/mib.0000000000000341

Meijer, B., Hoskin, T., Ashcroft, A., Burgess, L., Keenan, J. I., Falvey, J., Gearry, R. B., & Day, A. S. (2014). Total soluble and endogenous secretory receptor for advanced glycation endproducts (RAGE) in IBD. Journal of Crohn's & Colitis, 8(6), 513-520. doi: 10.1016/j.crohns.2013.11.004

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Conference Contribution - Published proceedings: Abstract

Dickerhof, N., Berry, L. J., Turner, R., Hoskin, T., Sly, P. D., & Kettle, A. J. (2016). Glutathione deficiency and neutrophil-mediated oxidative stress in the lungs of young children with cystic fibrosis. Free Radical Biology & Medicine, 100(Suppl.), (pp. S190). doi: 10.1016/j.freeradbiomed.2016.10.519

Falvey, J. D., Hoskin, T., Meijer, B., Ashcroft, A., Hampton, M. B., Day, A. S., & Gearry, R. B. (2012). Disease assessment in Crohn's disease (CD): Data from the Novel Biomarkers in Inflammatory Bowel Disease (NBIBD) project cohort. New Zealand Medical Journal, 125(1367). Retrieved from http://www.nzma.org.nz/journal

Falvey, J. D., Hoskin, T., Meijer, B., Ashcroft, A., Hampton, M. B., Day, A. S., & Gearry, R. B. (2012). Disease assessment in Ulcerative Colitis (UC): Data from the Novel Biomarkers in Inflammatory Bowel Disease (NBIBD) project cohort. New Zealand Medical Journal, 125(1367). Retrieved from http://www.nzma.org.nz/journal

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Conference Contribution - Verbal presentation and other Conference outputs

Dickerhof, N., Pearson, J. F., Hoskin, T. S., Sly, P. D., & Kettle, A. J. (2017, August). Myeloperoxidase is associated with bronchiectasis in children with cystic fibrosis. Verbal presentation at the 10th International Human Peroxidase Meeting, Breckenridge, USA.

Hoskin, T. S., Dickerhof, N., Hampton, M. B., & Kettle, A. J. (2017, July). Calprotectin is sensitive to oxidants generated by myeloperoxidase. Verbal presentation at the New Zealand Branch of the Australasian Society for Immunology (NZ ASI) Annual Scientific Meeting, Christchurch, New Zealand.

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Awarded Doctoral Degree

Hoskin, T. S. (2018). Oxidative post-transitional modifications of calprotectin during inflammation (PhD). University of Otago, Dunedin, New Zealand. Retrieved from http://hdl.handle.net/10523/8366

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