A postgraduate research opportunity at the University of Otago.
Details
- Close date
- Friday, 19 February 2021
- Academic background
- Sciences, Health Sciences
- Host campus
- Christchurch
- Qualification
- Honours
- Departments
- Medicine (Christchurch), Surgery (Christchurch), Pathology and Biomedical Science (Christchurch)
- Supervisors
- Dr Sarah Appleby, Dr Rachel Purcell, Associate Professor John Pearson, Professor Chris Pemberton
Overview
Recent evidence has shown that following myocardial infarction there is an increase in bacterial translocation ‘leaky gut’ into the systemic circulation, which initiates inflammation and consequently predisposes patients to cardiovascular events. This opens up the door to explore a novel set of biomarkers derived from the blood microbiome as risk assessment tools for cardiovascular disease (CVD).
This project will explore whether gut bacteria in the circulation of patients with CVD contributes to cardiovascular outcomes. We will use cutting-edge molecular biology techniques to:
- Classify the blood bacterial profile of patients with CVD and compare this to patients free of pre-existing CVD
- Identify blood microbiome-based biomarkers to more accurately identify patients at increased risk of CVD events
Further information
This is one of a number of projects on offer for the 2021 intake of BBiomedSc(Hons) at the University of Otago, Christchurch campus.
- UOC BBiomedSc(Hons) website
- Dr Sarah Appleby's profile
- Dr Rachel Purcell's profile
- Associate Professor John Pearson's profile
- Professor Chris Pemberton's profile
- Christchurch Heart Institute website
- Surgery Research Group website
- Department of Medicine website
- Department of Surgery website
- Department of Pathology and Biomedical Science website
