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Professor Christopher M.A. Frampton

Christopher FramptonProfessor

BSc(Hons) PhD(Cant)

Chris Frampton is the departmental biostatistician and is involved in departmental teaching and the design and analysis of research studies.

His particular research interests include the modelling and prediction of long-term outcome data, and developing structural equation models for defining personality constructs.

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Publications

Baxter-Parker, G., Roffe, L., Cross, S., Frampton, C., Hooper, G. J., & Gieseg, S. (2019). Knee replacement surgery significantly elevates the urinary inflammatory biomarkers neopterin and 7,8-dihydroneopterin. Clinical Biochemistry, 63, 39-45. doi: 10.1016/j.clinbiochem.2018.11.002

Nugent, M., Wyatt, M. C., Frampton, C. M., & Hooper, G. J. (2019). Despite improved survivorship of uncemented fixation in total knee replacement for osteoarthritis, cemented fixation remains the gold standard: An analysis of a National Joint Registry. Journal of Arthroplasty. Advance online publication. doi: 10.1016/j.arth.2019.03.047

Kumar, R., Pio, F., Brewer, J., Frampton, C., & Nicholls, M. (2019). Workplace wellbeing in an urban emergency department in Aotearoa New Zealand. Emergency Medicine Australasia. Advance online publication. doi: 10.1111/1742-6723.13262

Stamp, L. K., Frampton, C., Drake, J., Doughty, R. N., Troughton, R. W., & Richards, A. M. (2019). Associations of gout and baseline serum urate with cardiovascular outcomes: Analysis of the Coronary Disease Cohort Study. Arthritis & Rheumatology. Advance online publication. doi: 10.1002/art.41007

Lees, D., Frampton, C. M., & Merry, S. N. (2019). Efficacy of a home visiting enhancement for high-risk families attending parent management programs a randomized superiority clinical trial. JAMA Psychiatry, 76(3), 241-248. doi: 10.1001/jamapsychiatry.2018.4183

Journal - Research Article

Baxter-Parker, G., Roffe, L., Cross, S., Frampton, C., Hooper, G. J., & Gieseg, S. (2019). Knee replacement surgery significantly elevates the urinary inflammatory biomarkers neopterin and 7,8-dihydroneopterin. Clinical Biochemistry, 63, 39-45. doi: 10.1016/j.clinbiochem.2018.11.002

Lees, D., Frampton, C. M., & Merry, S. N. (2019). Efficacy of a home visiting enhancement for high-risk families attending parent management programs a randomized superiority clinical trial. JAMA Psychiatry, 76(3), 241-248. doi: 10.1001/jamapsychiatry.2018.4183

Stamp, L. K., Frampton, C., Drake, J., Doughty, R. N., Troughton, R. W., & Richards, A. M. (2019). Associations of gout and baseline serum urate with cardiovascular outcomes: Analysis of the Coronary Disease Cohort Study. Arthritis & Rheumatology. Advance online publication. doi: 10.1002/art.41007

Kumar, R., Pio, F., Brewer, J., Frampton, C., & Nicholls, M. (2019). Workplace wellbeing in an urban emergency department in Aotearoa New Zealand. Emergency Medicine Australasia. Advance online publication. doi: 10.1111/1742-6723.13262

Nugent, M., Wyatt, M. C., Frampton, C. M., & Hooper, G. J. (2019). Despite improved survivorship of uncemented fixation in total knee replacement for osteoarthritis, cemented fixation remains the gold standard: An analysis of a National Joint Registry. Journal of Arthroplasty. Advance online publication. doi: 10.1016/j.arth.2019.03.047

Beaglehole, B., Bloomer, C., Zhang, T., Hamilton, G., Boden, J. M., Mulder, R. T., Bell, C., & Frampton, C. (2019). The impact of the Canterbury earthquakes on dispensing for older person's mental health. International Journal of Geriatric Psychiatry. Advance online publication. doi: 10.1002/gps.5171

Lamba, M., Alamri, Y., Garg, P., Frampton, C., Rowbotham, D., & Gearry, R. (2019). Predictors of non-attendance at outpatient endoscopy: A five-year multi-centre observational study from New Zealand. New Zealand Medical Journal, 132(1496), 31-38. Retrieved from https://www.nzma.org.nz/journal

Maney, A. J., Koh, C. K., Frampton, C. M., & Young, S. W. (2019). Usually, selectively, or rarely resurfacing the patella during primary total knee arthroplasty: Determining the best strategy. Journal of Bone & Joint Surgery (Am), 101(5), 412-420. doi: 10.2106/jbjs.18.00389

Henzell, I. S., Zhou, L., Frampton, C., Hooper, G., Ackerman, I., & Young, S. W. (2019). Lifetime risk of primary total knee replacement surgery in New Zealand from 2000 to 2015. New Zealand Medical Journal, 132(1489), 48-56. Retrieved from https://www.nzma.org.nz/journal

Kennedy, J., Hoffman, T., Unasa, H., Frampton, C., Howard, A., Kiely, P. J., & Crawford, H. (2019). Thoracic proportions in children without scoliosis. Journal of Children's Orthopaedics, 13(3), 304-309. doi: 10.1302/1863-2548.13.180169

Ferguson, I., Moor, S., Frampton, C., & Withington, S. (2019). Rural youth in distress? Youth self-harm presentations to a rural hospital over 10 years. Journal of Primary Health Care, 11(2), 109-116. doi: 10.1071/HC19033

Vernon-Roberts, A., Lopez, R. N., Frampton, C., Gearry, R. B., Lemberg, D. A., & Day, A. S. (2019). A symptom self-report tool for children with inflammatory bowel disease (IBDnow). Journal of Pediatric Gastroenterology & Nutrition. Advance online publication. doi: 10.1097/MPG.0000000000002329

Aitken, P., Stanescu, I., Playne, R., Zhang, J., Frampton, C. M. A., & Atkinson, H. C. (2019). An integrated safety analysis of combined acetaminophen and ibuprofen (Maxigesic®/Combogesic®) in adults. Journal of Pain Research, 12, 621-634. doi: 10.2147/jpr.S189605

Gearry, R. B., Frampton, C., Inns, S., Poppelwell, D., Rademaker, M., & Suppiah, R. (2019). VITALITY: Impact of adalimumab on health and disability outcomes in patients with Crohn's disease, rheumatoid arthritis or psoriasis treated in clinical practice in New Zealand. Current Medical Research & Opinion. Advance online publication. doi: 10.1080/03007995.2019.1634952

Wyatt, M. C., Kieser, D. C., Kemp, M. A., McHugh, G., Frampton, C. M. A., & Hooper, G. J. (2019). Does the femoral offset affect replacements? The results from a National Joint Registry. HIP International, 29(3), 289-298. doi: 10.1177/1120700018780318

Eggleston, M. J. F., Thabrew, H., Frampton, C. M. A., Eggleston, K. H. F., & Hennig, S. C. (2019). Obtaining an autism spectrum disorder diagnosis and supports: New Zealand parents’ experiences. Research in Autism Spectrum Disorders, 62, 18-25. doi: 10.1016/j.rasd.2019.02.004

Dalbeth, N., Billington, K., Doyle, A., Frampton, C., Tan, P., Allan, J., … Stamp, L. K. (2019). Effects of allopurinol dose escalation on bone erosion and urate volume in gout: A dual energy CT imaging study of a randomized controlled trial. Arthritis & Rheumatology. Advance online publication. doi: 10.1002/art.40929

Lewis, L. K., Raudsepp, S. D., Prickett, T. C. R., Yandle, T. G., Doughty, R. N., Frampton, C. M., Pemberton, C. J., & Richards, A. M. (2019). ProBNP that is not glycosylated at threonine 71 is decreased with obesity in patients with heart failure. Clinical Chemistry. Advance online publication. doi: 10.1373/clinchem.2019.302547

Dixit, A., Frampton, C., Davey, V., Robinson, B., & James, M. (2019). Radiation treatment in early stage triple-negative breast cancer in New Zealand: A national database study. Journal of Medical Imaging & Radiation Oncology. Advance online publication. doi: 10.1111/1754-9485.12933

Dalbeth, N., Frampton, C., Fung, M., Baumgartner, S., Nicolaou, S., & Choi, H. K. (2019). Concurrent validity of provisional remission criteria for gout: A dual-energy CT study. Arthritis Research & Therapy, 21(1), 150. doi: 10.1186/s13075-019-1941-8

Hannam, J. A., Mitchell, S. J., Cumin, D., Frampton, C., Merry, A. F., Moore, M. R., & Kruger, C. J. (2018). Haemodynamic profiles of etomidate vs propofol for induction of anaesthesia: A randomised controlled trial in patients undergoing cardiac surgery. British Journal of Anaesthesia. Advance online publication. doi: 10.1016/j.bja.2018.09.027

Rucklidge, J. J., Eggleston, M. J. F., Darling, K., Stevens, A., Kennedy, M., & Frampton, C. M. (2018). Can we predict treatment response in children with ADHD to a vitamin-mineral supplement? An investigation into pre-treatment nutrient serum levels, MTHFR status, clinical correlates and demographic variables. Progress in Neuro-Psychopharmacology & Biological Psychiatry. Advance online publication. doi: 10.1016/j.pnpbp.2018.09.007

Stamp, L. K., Chapman, P. T., Barclay, M. L., Horne, A., Frampton, C., Tan, P., … Dalbeth, N. (2018). How much allopurinol does it take to get to target urate? Comparison of actual dose with creatinine clearance-based dose. Arthritis Research & Therapy, 20, 255. doi: 10.1186/s13075-018-1755-0

Robinson, B., Dijkstra, B., Davey, V., Tomlinson, S., & Frampton, C. (2018). Adherence to adjuvant endocrine therapy in Christchurch women with early breast cancer. Clinical Oncology, 30(1), e9-e15. doi: 10.1016/j.clon.2017.10.015

Stamp, L. K., Chapman, P. T., Barclay, M., Horne, A., Frampton, C., Tan, P., … Dalbeth, N. (2018). Can we predict inadequate response to allopurinol dose escalation? Analysis of a randomised controlled trial. Rheumatology, 57(12), 2183-2189. doi: 10.1093/rheumatology/key237

James, M., Dixit, A., Robinson, B., Frampton, C., & Davey, V. (2018). Outcomes for patients with non-metastatic triple-negative breast cancer in New Zealand. Clinical Oncology. Advance online publication. doi: 10.1016/j.clon.2018.09.006

Beaglehole, B., Mulder, R. T., Frampton, C. M., Boden, J. M., Newton-Howes, G., & Bell, C. J. (2018). Psychological distress and psychiatric disorder after natural disasters: Systematic review and meta-analysis. British Journal of Psychiatry, 213(6), 716-722. doi: 10.1192/bjp.2018.210

Ooi, C., Solanki, K., Lao, C., Frampton, C., & White, D. (2018). Mortality in the Waikato Hospital systemic sclerosis cohort. International Journal of Rheumatic Diseases, 21(1), 253-260. doi: 10.1111/1756-185x.13111

Carter, J. D., McIntosh, V. V. W., Jordan, J., Porter, R. J., Douglas, K., Frampton, C. M., & Joyce, P. R. (2018). Patient predictors of response to cognitive behaviour therapy and schema therapy for depression. Australian & New Zealand Journal of Psychiatry, 52(9), 887-897. doi: 10.1177/0004867417750756

Than, M. P., Pickering, J. W., Dryden, J. M., Lord, S. J., Aitken, S. A., Aldous, S. J., … Ardagh, M. W., … Callender, R., … Deely, J. M., … Ferrier, K. A., … Frampton, C. M. A., George, P. M., … Matthews, T. J. E., … Peckler, B. F., … Richards, A. M., … Simmonds, M. B., … Troughton, R. W., … on behalf of the ICare-ACS Implementation Group. (2018). ICare-ACS (improving care processes for patients with suspected acute coronary syndrome): A study of cross-system implementation of a national clinical pathway. Circulation, 137(4), 354-363. doi: 10.1161/circulationaha.117.031984

Smith, J. O., Frampton, C. M. A., Hooper, G. J., & Young, S. W. (2018). The impact of patient and surgical factors on the rate of postoperative infection after total hip arthroplasty: A New Zealand Joint Registry Study. Journal of Arthroplasty, 33(6), 1884-1890. doi: 10.1016/j.arth.2018.01.021

Daniels, S. E., Atkinson, H. C., Stanescu, I., & Frampton, C. (2018). Analgesic efficacy of an acetaminophen/ibuprofen fixed-dose combination in moderate to severe postoperative dental pain: A randomized, double-blind, parallel-group, placebo-controlled trial. Clinical Therapeutics, 40(10), 1765-1776.e5. doi: 10.1016/j.clinthera.2018.08.019

Sturman, C. J., Frampton, C. M., & Ten Cate, W. J. F. (2018). Hearing loss asymmetry due to chronic occupational noise exposure. Otology & Neurotology, 39(8), e627-e634. doi: 10.1097/mao.0000000000001908

Monasterio, E., McKean, A., Sinhalage, V., Frampton, C., & Mulder, R. (2018). Sudden death in patients with serious mental illness. New Zealand Medical Journal, 131(1487), 70-79. Retrieved from https://www.nzma.org.nz/journal

Inder, M. L., Crowe, M. T., Moor, S., Carter, J. D., Luty, S. E., Frampton, C. M., & Joyce, P. R. (2018). Three-year follow-up after psychotherapy for young people with bipolar disorder. Bipolar Disorders, 20(5), 441-447. doi: 10.1111/bdi.12582

Chambers, C. N. L., Frampton, C. M. A., McKee, M., & Barclay, M. (2018). 'It feels like being trapped in an abusive relationship': Bullying prevalence and consequences in the New Zealand senior medical workforce: A cross-sectional study. BMJ Open, 8(3), e020158. doi: 10.1136/bmjopen-2017-020158

Bell, C. J., Frampton, C. M., Colhoun, H. C., Douglas, K. M., McIntosh, V. V. W., Carter, F. A., Jordan, J., … Porter, R. J. (2018). Earthquake brain: Impairment of spatial memory following long-term earthquake-related stress. Australian & New Zealand Journal of Psychiatry. Advance online publication. doi: 10.1177/0004867418789498

Wilson, R., Willis, J., Gearry, R. B., Hughes, A., Lawley, B., Skidmore, P., Frampton, C., Fleming, E., Anderson, A., Jones, L., Tannock, G. W., & Carr, A. C. (2018). SunGold kiwifruit supplementation of individuals with prediabetes alters gut microbiota and improves Vitamin C status, anthropometric and clinical markers. Nutrients, 10, 895. doi: 10.3390/nu10070895

Zhou, J., Reddy, M. V., Wilson, B. K. J., Blair, D. A., Taha, A., Frampton, C. M., Eiholzer, R. A., … Hung, N. A., Royds, J. A., & Slatter, T. L. (2018). MR imaging characteristics associate with tumor-associated macrophages in glioblastoma and provide an improved signature for survival prognostication. American Journal of Neuroradiology, 39(2), 252-259. doi: 10.3174/ajnr.A5441

Averill, I. R. E., Crowe, M., Frampton, C. M., Beaglehole, B., Lacey, C. J., Jordan, J., Wilson, L. D., Douglas, K. M., & Porter, R. J. (2018). Clinical response to treatment in inpatients with depression correlates with changes in activity levels and psychomotor speed. Australian & New Zealand Journal of Psychiatry, 52(7), 652-659. doi: 10.1177/0004867417753549

Paulides, E., Kim, C., Frampton, C., Gearry, R. B., Eglinton, T., Leong, R. W., … McCombie, A. M. (2018). Validation of the Inflammatory Bowel Disease Disability Index for self-report and development of an item-reduced version. Journal of Gastroenterology & Hepatology. Advance online publication. doi: 10.1111/jgh.14496

Noller, G. E., Frampton, C. M. A., & Yazar-Klosinski, B. (2018). Ibogaine treatment outcomes for opioid dependence from a twelve-month follow-up observational study. American Journal of Drug & Alcohol Abuse, 44(1), 37-46. doi: 10.1080/00952990.2017.1310218

Deering, D. E. A., Adamson, S. J., Sellman, J. D., Henderson, C., Sheridan, J., Pooley, S., … Noller, G., & Frampton, C. M. A. (2018). Potential risk for fatal drug overdose perceived by people using opioid drugs. Drug & Alcohol Review, 37(S1), S309-S313. doi: 10.1111/dar.12635

Douglas, K. M., Gallagher, P., Robinson, L. J., Carter, J. D., McIntosh, V. V. W., Frampton, C. M. A., … Porter, R. J. (2018). Prevalence of cognitive impairment in major depression and bipolar disorder. Bipolar Disorders, 20(3), 260-274. doi: 10.1111/bdi.12602

de Carvalho, L., Fong, A., Troughton, R., Yan, B. P., Chin, C.-T., Poh, S.-C., … Frampton, C., Richards, A. M., & Chan, M. Y. (2018). Prognostic implications of dual platelet reactivity testing in acute coronary syndrome. Thrombosis & Haemostasis, 118(2), 415-426. doi: 10.1160/TH17-08-0564

Marks, E. C. A., Wilkinson, T. M., Frampton, C. M., Skelton, L., Pilbrow, A. P., Yandle, T. G., Pemberton, C. J., … Whalley, G. A., … Troughton, R. W., … Cameron, V. A., Richards, A. M., Gieseg, S. P., & Palmer, B. R. (2018). Plasma levels of soluble VEGF receptor isoforms, circulating pterins and VEGF system SNPs as prognostic biomarkers in patients with acute coronary syndromes. BMC Cardiovascular Disorders, 18, 169. doi: 10.1186/s12872-018-0894-1

Snow, B., Mulroy, E., Bok, A., Simpson, M., Smith, A., Taylor, K., … Frampton, C., … Macdonald, L. (2018). A phase IIb, randomised, double-blind, placebo-controlled, dose-ranging investigation of the safety and efficacy of NTCELL® [immunoprotected (alginate-encapsulated) porcine choroid plexus cells for xenotransplantation] in patients with Parkinson's disease. Parkinsonism & Related Disorders. Advance online publication. doi: 10.1016/j.parkreldis.2018.11.015

Meijer, B., van Everdingen, C. K., Ramsoekh, D., Stedman, C., Frampton, C. M. A., Mulder, C. J. J., … Gearry, R. B. (2018). Transient elastography to assess liver stiffness in patients with inflammatory bowel disease. Digestive & Liver Disease, 50(1), 48-53. doi: 10.1016/j.dld.2017.09.128

Rucklidge, J. J., Eggleston, M. J. F., Johnstone, J. M., Darling, K., & Frampton, C. M. (2018). Vitamin-mineral treatment improves aggression and emotional regulation in children with ADHD: A fully blinded, randomized, placebo-controlled trial. Journal of Child Psychology & Psychiatry, 59(3), 232-246. doi: 10.1111/jcpp.12817

Storey, R., Frampton, C., Kieser, D., & Hooper, G. (2018). Does orthopaedic training compromise the outcome in knee joint arthroplasty? Journal of Surgical Education, 75(5), 1292-1298. doi: 10.1016/j.jsurg.2018.02.011

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