Associate Professor Jacqui Keenan

Ali, H., Douwes, J., Burmanje, J., Gokhale, P., Crane, J., Pattemore, P., Stanley, T., Keenan, J., & Brooks, C. (2023). Sputum inflammatory, neural, and remodelling mediators in eosinophilic and non-eosinophilic asthma. Annals of Allergy, Asthma & Immunology. Advance online publication. doi: 10.1016/j.anai.2023.03.015

Journal - Research Article

James, S. C., Fraser, K., Cooney, J., Günther, C. S., Young, W., Gearry, R. B., … Keenan, J. I., … Roy, N. C. (2023). Concentrations of plasma amino acids and neurotransmitters in participants with functional gut disorders and healthy controls. Metabolites, 13, 313. doi: 10.3390/metabo13020313

Journal - Research Article

Simon, M. H., Heenan, P. E., Frampton, C., Bayer, S., Keenan, J. I., de Boer, N. K., Roy, N. C., … Gearry, R. B. (2023). Economic living standard and abdominal pain mediate the association between functional gastrointestinal disorders and depression or anxiety. Neurogastroenterology & Motility, 35, e14465. doi: 10.1111/nmo.14465

Journal - Research Article

Thompson, N., Gatenby, G., Waddell, O., Purcell, R., Keenan, J., Pearson, J., Frizelle, F., & Glyn, T. (2023). Early onset colorectal cancer in Canterbury, New Zealand. ANZ Journal of Surgery. Advance online publication. doi: 10.1111/ans.18357

Journal - Research Article

Aitchison, A., Pearson, J. F., Purcell, R. V., Frizelle, F. A., & Keenan, J. I. (2022). Detection of Fusobacterium nucleatum DNA in primary care patient stool samples does not predict progression of colorectal neoplasia. PLoS ONE, 17(6), e0269541. doi: 10.1371/journal.pone.0269541

Journal - Research Article

Ho, S. S. C., Hall, S., Keenan, J. I., & Day, A. S. (2022). Australasian pediatric gastroenterologists' perspectives and practices of Celiac disease diagnosis and management. Digestive Diseases & Sciences, 67, 1744-1752. doi: 10.1007/s10620-021-06988-2

Journal - Research Article

Purcell, R. V., Permain, J., & Keenan, J. I. (2022). Enterotoxigenic Bacteroides fragilis activates IL-8 expression through Stat3 in colorectal cancer cells. Gut Pathogens, 14, 16. doi: 10.1186/s13099-022-00489-x

Journal - Research Article

Edwards, T. S., Dawson, K. L., Keenan, J. I., & Day, A. S. (2021). A simple method to generate β-casomorphin-7 by in vitro digestion of casein from bovine milk. Journal of Functional Foods, 85, 104631. doi: 10.1016/j.jff.2021.104631

Journal - Research Article

Ho, S. S. C., Keenan, J. I., & Day, A. S. (2021). Parent Perspectives of Diagnostic and Monitoring Tests Undertaken by Their Child with Inflammatory Bowel Disease. Pediatric Gastroenterology, Hepatology & Nutrition, 24(1), 19-29. doi: 10.5223/pghn.2021.24.1.19

Journal - Research Article

James, S. C., Fraser, K., Young, W., Heenan, P. E., Gearry, R. B., Keenan, J. I., … Roy, N. C. (2021). Concentrations of fecal bile acids in participants with functional gut disorders and healthy controls. Metabolites, 11, 612.

Journal - Research Article

Aitchison, A., Hakkaart, C., Day, R. C., Morrin, H. R., Frizelle, F. A., & Keenan, J. I. (2020). APC mutations are not confined to hotspot regions in early-onset colorectal cancer. Cancers, 12, 3829. doi: 10.3390/cancers12123829

Journal - Research Article

Aitchison, A., Hakkaart, C., Whitehead, M., Khan, S., Siddique, S., Ahmed, R., Frizelle, F. A., & Keenan, J. I. (2020). CDH1 gene mutation in early-onset, colorectal signet-ring cell carcinoma. Pathology: Research & Practice, 216, 152912. doi: 10.1016/j.prp.2020.152912

Journal - Research Article

Heenan, P., Creemers, R. H., Sharma, S., Keenan, J., Bayer, S., Young, W., … Skidmore, P. M., … Roy, N., Gearry, R. B., & COMFORT Cohort Collaborators. (2020). Cohort profile: The Christchurch IBS cOhort to investigate Mechanisms FOr gut Relief and improved Transit (COMFORT). Inflammatory Intestinal Diseases, 5(3), 132-143. doi: 10.1159/000508160

Journal - Research Article

Ho, S. S. C., Keenan, J. I., & Day, A. S. (2020). Role of serological tests in the diagnosis of coeliac disease in children in New Zealand. Journal of Paediatrics & Child Health, 56, 1906-1911. doi: 10.1111/jpc.15076

Journal - Research Article

Ho, S. S. C., Ross, M., Keenan, J. I., & Day, A. S. (2020). Fecal calprotectin in combination with standard blood tests in the diagnosis of inflammatory bowel disease in children. Frontiers in Pediatrics, 8, 609279. doi: 10.3389/fped.2020.609279

Journal - Research Article

Ho, S. S., Wall, C., Gearry, R. B., Keenan, J., & Day, A. S. (2020). A pilot study evaluating novel urinary biomarkers for Crohn's disease. Inflammatory Intestinal Diseases, 5(4), 212-220. doi: 10.1159/000510682

Journal - Research Article

Keenan, J., Aitchison, A., Leaman, J., Pearson, J., & Frizelle, F. (2019). Faecal biomarkers do not always identify pre-cancerous lesions in patients who present in primary care with bowel symptoms. New Zealand Medical Journal, 132(1501), 48-56. Retrieved from https://www.nzma.org.nz/journal

Journal - Research Article

Purcell, R. V., Kaakoush, N. O., Mitchell, H. M., Pearson, J. F., & Keenan, J. I. (2018). Gastrointestinal pathobionts in pediatric Crohn's disease patients. International Journal of Microbiology, 2018, 9203908. doi: 10.1155/2018/9203908

Journal - Research Article

Budd, G. R., Aitchison, A., Day, A. S., & Keenan, J. I. (2017). The effect of polymeric formula on enterocyte differentiation. Innate Immunity, 23(3), 240-248. doi: 10.1177/1753425916689333

Journal - Research Article

Chae, A., Aitchison, A., Day, A. S., & Keenan, J. I. (2017). Bovine colostrum demonstrates anti-inflammatory and antibacterial activity in in vitro models of intestinal inflammation and infection. Journal of Functional Foods, 28, 293-298. doi: 10.1016/j.jff.2016.11.016

Journal - Research Article

Flores, S. E., Aitchison, A., Day, A. S., & Keenan, J. I. (2017). Helicobacter pylori infection perturbs iron homeostasis in gastric epithelial cells. PLoS ONE, 12(9), e0184026. doi: 10.1371/journal.pone.0184026

Journal - Research Article

Purcell, R. V., Pearson, J., Aitchison, A., Dixon, L., Frizelle, F. A., & Keenan, J. I. (2017). Colonization with enterotoxigenic Bacteroides fragilis is associated with early-stage colorectal neoplasia. PLoS ONE, 12(2), e0171602. doi: 10.1371/journal.pone.0171602

Journal - Research Article

Aitchison, A., Frizelle, F. A., & Keenan, J. I. (2016). PCR detection of the Bacteroides fragilis enterotoxin gene relies on robust primer design. Journal of Clinical Microbiology, 54(1), 239-240. doi: 10.1128/jcm.02785-15

Journal - Research Article

Keenan, J. I., Aitchison, A., Purcell, R. V., Greenlees, R., Pearson, J. F., & Frizelle, F. A. (2016). Screening for enterotoxigenic Bacteroides fragilis in stool samples. Anaerobe, 40, 50-53. doi: 10.1016/j.anaerobe.2016.05.004

Journal - Research Article

Purcell, R. V., Pearson, J., Frizelle, F. A., & Keenan, J. I. (2016). Comparison of standard, quantitative and digital PCR in the detection of enterotoxigenic Bacteroides fragilis. Scientific Reports, 6, 34554. doi: 10.1038/srep34554

Journal - Research Article

Wakeman, C., Keenan, J., Eteuati, J., Hollington, P., Eglinton, T., & Frizelle, F. (2016). Chemoprevention of colorectal neoplasia. ANZ Journal of Surgery, 87(12), E228-E232. doi: 10.1111/ans.13392

Journal - Research Article

Wright, E. K., Kamm, M. A., De Cruz, P., Hamilton, A. L., Ritchie, K. J., Keenan, J. I., … Burgess, L., Aitchison, A., … Day, A. S., & Gearry, R. B. (2016). Comparison of fecal inflammatory markers in Crohn's disease. Inflammatory Bowel Diseases, 22(5), 1086-1094. doi: 10.1097/mib.0000000000000671

Journal - Research Article

Flores, S. E., Day, A. S., & Keenan, J. I. (2015). Measurement of total iron in Helicobacter pylori-infected gastric epithelial cells. Biometals, 28, 143-150. doi: 10.1007/s10534-014-9810-z

Journal - Research Article

Keenan, J. I., Hooper, E. M., Tyrer, P. C., & Day, A. S. (2014). Influences of enteral nutrition upon CEACAM6 expression by intestinal epithelial cells. Innate Immunity, 20(8), 848-856. doi: 10.1177/1753425913513309

Journal - Research Article

Meijer, B., Hoskin, T., Ashcroft, A., Burgess, L., Keenan, J. I., Falvey, J., Gearry, R. B., & Day, A. S. (2014). Total soluble and endogenous secretory receptor for advanced glycation endproducts (RAGE) in IBD. Journal of Crohn's & Colitis, 8(6), 513-520. doi: 10.1016/j.crohns.2013.11.004

Journal - Research Article

Tyrer, P. C., Frizelle, F. A., & Keenan, J. I. (2014). Escherichia coli-derived outer membrane vesicles are genotoxic to human enterocyte-like cells. Infectious Agents & Cancer, 9, 2. doi: 10.1186/1750-9378-9-2

Journal - Research Article

Keenan, J. I., Salm, N., Pearson, J. F., Gearry, R. B., & Day, A. S. (2013). Campylobacter seroreactivity in adults with recent onset of Crohn’s disease. Journal of Gastroenterology & Hepatology Research, 2(3), 468-472. doi: 10.6051/j.issn.2224-3992.2013.02.228

Journal - Research Article

Bentley, R. W., Keown, D. A., Gearry, R. B., Cameron, V. A., Keenan, J., Roberts, R. L., & Day, A. S. (2012). Vitamin D receptor polymorphisms in colorectal cancer in New Zealand: An association study. New Zealand Medical Journal, 125(1356). Retrieved from http://www.nzma.org.nz/journal

Journal - Research Article

Coray, D. S., Heinemann, J. A., Tyrer, P. C., & Keenan, J. I. (2012). Human lactoferrin increases Helicobacter pylori internalisation into AGS cells. World Journal of Microbiology & Biotechnology, 28(5), 1871-1880. doi: 10.1007/s11274-011-0984-z

Journal - Research Article

Keenan, J. I., Salm, N., Wallace, A. J., & Hampton, M. B. (2012). Using food to reduce H. pylori-associated inflammation. Phytotherapy Research, 26(11), 1620-1625. doi: 10.1002/ptr.4618

Journal - Research Article

Keown, D. A., Collings, D. A., & Keenan, J. I. (2012). Uptake and persistence of Mycobacterium avium subsp. paratuberculosis in human monocytes. Infection & Immunity, 80(11), 3768-3775. doi: 10.1128/iai.00534-12

Journal - Research Article

Parker, H., & Keenan, J. I. (2012). Composition and function of Helicobacter pylori outer membrane vesicles. Microbes & Infection, 14(1), 9-16. doi: 10.1016/j.micinf.2011.08.007

Journal - Research Article

Day, A. S., & Keenan, J. (2011). Probiotic-mediated modulation of host inflammation. Expert Review of Gastroenterology & Hepatology, 5(3), 319-321. doi: 10.1586/egh.11.34

Journal - Research Article

Glubb, D. M., Gearry, R. B., Barclay, M. L., Roberts, R. L., Pearson, J., Keenan, J. I., McKenzie, J., & Bentley, R. W. (2011). NOD2 and ATG16L1 polymorphisms affect monocyte responses in Crohn's disease. World Journal of Gastroenterology, 17(23), 2829-2837. doi: 10.3748/wjg.v17.i23.2829

Journal - Research Article

Keenan, J. I., Beaugie, C. R., Jasmann, B., Potter, H. C., Collett, J. A., & Frizelle, F. A. (2010). Helicobacter species in the human colon. Colorectal Disease, 12(1), 48-53. doi: 10.1111/j.1463-1318.2008.01672.x

Journal - Research Article

Keenan, J. I., Salm, N., Hampton, M. B., & Wallace, A. J. (2010). Individual and combined effects of foods on Helicobacter pylori growth. Phytotherapy Research, 24(8), 1229-1233. doi: 10.1002/ptr.3167

Journal - Research Article

Parker, H., Chitcholtan, K., Hampton, M. B., & Keenan, J. I. (2010). Uptake of Helicobacter pylori outer membrane vesicles by gastric epithelial cells. Infection & Immunity, 78(12), 5054-5061. doi: 10.1128/IAI.00299-10

Journal - Research Article

Munday, J. S., Keenan, J. I., Beaugie, C. R., & Sugiarto, H. (2009). Ovine small intestinal adenocarcinomas are not associated with infection by herpesviruses, Helicobacter species or Mycobacterium avium subspecies paratuberculosis. Journal of Comparative Pathology, 140(2-3), 177-181. doi: 10.1016/j.jcpa.2008.11.005

Journal - Research Article

Bentley, R. W., Keenan, J. I., Gearry, R. B., Kennedy, M. A., Barclay, M. L., & Roberts, R. L. (2008). Incidence of Mycobacterium avium subspecies paratuberculosis in a population-based cohort of patients with Crohn's disease and control subjects. American Journal of Gastroenterology, 103(5), 1168-1172. doi: 10.1111/j.1572-0241.2007.01742.x

Journal - Research Article

Chitcholtan, K., Hampton, M. B., & Keenan, J. I. (2008). Outer membrane vesicles enhance the carcinogenic potential of Helicobacter pylori. Carcinogenesis, 29(12), 2400-2405. doi: 10.1093/carcin/bgn218

Journal - Research Article

Keenan, J. I., Davis, K. A., Beaugie, C. R., McGovern, J. J., & Moran, A. P. (2008). Alterations in Helicobacter pylori outer membrane and outer membrane vesicle-associated lipopolysaccharides under iron-limiting growth conditions. Innate Immunity, 14(5), 279-290. doi: 10.1177/1753425908096857

Journal - Research Article

Piuhola, J., Kerkelä, R., Keenan, J. I., Hampton, M. B., Richards, A. M., & Pemberton, C. J. (2008). Direct cardiac actions of erythropoietin (EPO): Effects on cardiac contractility, BNP secretion and ischaemia/reperfusion injury. Clinical Science, 114(4), 293-304. doi: 10.1042/CS20070229

Journal - Research Article

Mandhan, P., Qi, B. Q., Keenan, J. I., Ismail, S., Beasley, S. W., & Sullivan, M. J. (2006). Counterstaining improves visualization of the myenteric plexus in immunolabelled whole-mount preparations. Journal of Fluorescence, 16, 655-658.

Journal - Research Article

Hynes, S. O., Keenan, J. I., Ferris, J. A., Annuk, H., & Moran, A. P. (2005). Lewis epitopes on outer membrane vesicles of relevance to Helicobacter pylori pathogenesis. Helicobacter, 10(2), 146-156.

Journal - Research Article

Keenan, J. I., Peterson, II, R. A., & Hampton, M. B. (2005). NADPH oxidase involvement in the pathology of Helicobacter pylori infection. Free Radical Biology & Medicine, 38, 1188-1196.

Journal - Research Article