Director, General Practice Research Group
MB ChB DPH(Otago)
Director, McMaster University Sentinel and Information Collaboration (M.U.S.I.C.)
Email dee.mangin@otago.ac.nz
Research Interests
Dee Mangin is a New Zealand family physician who is currently Professor and Director of the Primary Care Research Group at the University of Otago, Christchurch. She is also the David Braley Nancy Gordon Chair in Family Medicine at McMaster University, Canada.
Her interests are rational prescribing, and the influences of science, policy and commerce on the nature of care.
Expertise spans generation of clinical evidence using randomised controlled trials, the effects of pharmaceutical company promotion to consumers and physicians, effective medicine use in older age, innovative models of general practice care and effective incorporation of evidence into patient-centered practice.
She has been a member of the Pharmaceutical and Therapeutic Products Advisory Committee.
Student Supervision
Nagham Ailabouni
Degree: PhD
Topic: De-prescribing discontinuation of unnecessary medicines in frail older people in New Zealand.
Supervisors: Dr June Tordoff, Professor Dee Mangin and Dr Prasad Nishtala
2014-15
Abigail Boyer
Topic: Evaluation of Pegasus Health's "Stop Smoking Support Options" Programme
Supervisors: Dr Lynley Cook and Associate Professor Dee Mangin
Sponsor: Pegasus Health (Charitable) Ltd
2012-13
Matthew Chamberlain
Topic: Psychological impact of September 2010 and subsequent earthquakes on Christchurch general practice patients.
Supervisors: Dee Mangin, Cerina Altenburg
Sponsor: The Royal New Zealand College of General Practitioners
Georgie Malcolm
Topic: Developing an evidence based pathway for UTI management in the primary/urgent care setting.
Supervisor: Dee Mangin
Co-supervisor: Louisa Sullivan
Sponsor: Pegasus Health
2010-11
Jasmine Gooda
Topic: Low dose antipsychotic use and metabolic side effects.
Supervisor: Dee Mangin
Sponsor: Pegasus Health
2009-10
Monica Johnson
Topic: Polypharmacy in the elderly – evaluating the Pill Pruner project.
Supervisors: Dee Mangin, Andrea Copeland, Nikki Ford
Sponsor: Pegasus Health
2008-09
Lauren Cumberpatch
Topic: The views of older adults on medicine use in treatment and prevention.
Supervisors: Dee Mangin & Kim Burgess
Sponsor: The Canterbury Health Care of the Elderly Education Trust
2007-08
Meagan McLeod ()
Topic: Comparison of the effectiveness of General Practice cervical screening systems.
Supervisor: Dee Mangin
Co-Supervisor Vivian Daley [Pegasus Health]
Sponsor: Pegasus Health IPA
2005-06
Charlotte Duncan
Topic: What are the drivers of PSA testing in Pegasus GPs?
Supervisors: Paul Corwin, Dee Mangin
Sponsor: Otago Theme Bursary, University of Otago
2004-05
Kris Wilson
Topic: A comparison of parental attitudes towards complementary and alternative medicines in children.
Supervisors: Dee Richards and Claire Dowson
Publications
Tinwala, M., Zaidi, D., Ye, F., Muneer, S., Ghimire, A., Khan, M., … Mangin, D., & Bello, K. A. (2022). Prevalence of polypharmacy and associated adverse health outcomes in patients with CKD: A systematic review and meta-analysis. Kidney International Reports, 7(2, Suppl.), (pp. S141-S142). doi: 10.1016/S2468-0249(22)01080-4
Tinwala, M., Zaidi, D., Ye, F., Muneer, S., Ghimire, A., Khan, M., … Mangin, D., & Bello, K. A. (2022). Polypharmacy and potentially inappropriate medication use in patients with CKD managed in Canadian primary care. Kidney International Reports, 7(2, Suppl.), (pp. S141). doi: 10.1016/S2468-0249(22)01080-4
Gaber, J., Di Pelino, S., Datta, J., Talat, S., Browne, T., Marentette-Brown, S., … Mangin, D. (2022). Community volunteers and primary care providers supporting older adults in system navigation: A mixed methods study. International Journal of Integrated Care, 22(1), 18. doi: 10.5334/ijic.5978
Gaber, J., Clark, R. E., Lamarche, L., Datta, J., Talat, S., Bomze, S., … Mangin, D. (2022). Understanding volunteer retention in a complex, community-centred intervention: A mixed methods study in Ontario, Canada. Health & Social Care in the Community. Advance online publication. doi: 10.1111/hsc.13775
Gaber, J., Datta, J., Clark, R., Lamarche, L., Parascandalo, F., Di Pelino, S., … Mangin, D., & Price, D. (2022). Understanding how context and culture in six communities can shape implementation of a complex intervention: A comparative case study. BMC Health Services Research, 22, 221. doi: 10.1186/s12913-022-07615-0
Ingham, T., Jones, B., on behalf of the Pharmacovigilance Ethics Advisory Group, including Smith, B., Mangin, D., & Moore, A. (Eds.). (2012). Medicine safety for New Zealanders: Ethical issue regarding the use of routinely collected data from general practice for pharmacovigilance (Draft ed.). Wellington, New Zealand: University Of Otago, 46p.
Edited Book - Research
Mintzes, B., Mangin, D., & Hayes, L. (Eds.). (2009). Understanding and responding to pharmaceutical promotion: A practical guide [Working draft for pilot field testing]. World Health Organization & Health Action International. Retrieved from http://www.haiweb.org/11062009/drug-promotion-manual-CAP-3-090610.pdf
Edited Book - Research
Healy, D., & Mangin, D. (2016). Does my bias look big in this? In F. Baylis & A. Ballantyne (Eds.), Clinical research involving pregnant women. (pp. 197-208). Springer. doi: 10.1007/978-3-319-26512-4_11
Chapter in Book - Research
Mangin, D. (2016). The contribution of primary care research to improving health services. In F. Goodyear-Smith & B. Mash (Eds.), International perspectives on primary care research. (pp. 67-72). Boca Raton, FL: CRC Press.
Chapter in Book - Research
Mangin, D. (2015). A primary care perspective on prescribing for women. In M. Harrison-Woolrych (Ed.), Medicines for women. (pp. 403-432). Springer.
Chapter in Book - Research
Mangin, D., & Heath, I. (2012). Polifarmácia [Polypharmacy]. In G. Gusso & J. M. C. Lopes (Eds.), Tratado de medicina de família e comunidadae [Textbook of family and community medicine]. (pp. 198-204). artmed.
Chapter in Book - Research
Starfield, B., & Mangin, D. (2011). An international perspective on the basis of pay-for-performance. In S. Gillam & A. N. Siriwardena (Eds.), The quality and outcomes framework (QOF): Transforming general practice. (pp. 147-155). Abingdon, UK: Radcliffe.
Chapter in Book - Research
Mangin, D. (2009). Promotion, professional practice and patient trust. In B. Mintzes, D. Mangin & L. Hayes (Eds.), Understanding and responding to pharmaceutical promotion: A practical guide [Working draft for pilot field testing]. (pp. 163-173). World Health Organization & Health Action International. Retrieved from http://www.haiweb.org/11062009/drug-promotion-manual-CAP-3-090610.pdf
Chapter in Book - Research
Mintzes, B., Toop, L., & Mangin, D. (2009). Promotion to consumers: Responding to patient requests for advertised medicines. In B. Mintzes, D. Mangin & L. Hayes (Eds.), Understanding and responding to pharmaceutical promotion: A practical guide [Working draft for pilot field testing]. (pp. 81-104). World Health Organization & Health Action International. Retrieved from http://www.haiweb.org/11062009/drug-promotion-manual-CAP-3-090610.pdf
Chapter in Book - Research
Toop, L., & Mangin, D. (2013). Marketing of pharmaceuticals. In P. Joyce, G. Nicholls, K. Thomas & T. Wilkinson (Eds.), The Christchurch experience: 40 years of research and teaching. (pp. 177-182). Christchurch, New Zealand: University of Otago.
Chapter in Book - Other
Gaber, J., Clark, R. E., Lamarche, L., Datta, J., Talat, S., Bomze, S., … Mangin, D. (2022). Understanding volunteer retention in a complex, community-centred intervention: A mixed methods study in Ontario, Canada. Health & Social Care in the Community. Advance online publication. doi: 10.1111/hsc.13775
Journal - Research Article
Gaber, J., Datta, J., Clark, R., Lamarche, L., Parascandalo, F., Di Pelino, S., … Mangin, D., & Price, D. (2022). Understanding how context and culture in six communities can shape implementation of a complex intervention: A comparative case study. BMC Health Services Research, 22, 221. doi: 10.1186/s12913-022-07615-0
Journal - Research Article
Gaber, J., Di Pelino, S., Datta, J., Talat, S., Browne, T., Marentette-Brown, S., … Mangin, D. (2022). Community volunteers and primary care providers supporting older adults in system navigation: A mixed methods study. International Journal of Integrated Care, 22(1), 18. doi: 10.5334/ijic.5978
Journal - Research Article
Morrow, R. L., Mintzes, B., Souverein, P. C., De Bruin, M., Roughead, E. E., Lexchin, J., … Mangin, D., … Dormuth, C. R. (2022). Influence of drug safety advisories on drug utilization: An international interrupted time series and meta-analysis study. BMJ Quality & Safety. Advance online publication. doi: 10.1136/bmjqs-2021-013910
Journal - Research Article
Aponte-Hao, S., Wong, S. T., Thandi, M., Ronksley, P., McBrien, K., Lee, J., … Mangin, D., … Williamson, T. (2021). Machine learning for identification of frailty in Canadian primary care practices. International Journal of Population Data Science, 6(1), 11. doi: 10.23889/ijpds.v6i1.1650
Journal - Research Article
Duffy, L., Clarke, C. S., Lewis, G., Marston, L., Freemantle, N., Gilbody, S., … Mangin, D., … Lewis, G. (2021). Antidepressant medication to prevent depression relapse in primary care: The ANTLER RCT. Health Technology Assessment, 25(69), 1-62. doi: 10.3310/hta25690
Journal - Research Article
Healy, D., Bahrick, A., Bak, M., Barbato, A., Calabrò, R. S., Chubak, B. M., … Mangin, D., … Waraich, A. (2021). Diagnostic criteria for enduring sexual dysfunction after treatment with antidepressants, finasteride and isotretinoin. International Journal of Risk & Safety in Medicine. Advance online publication. doi: 10.3233/JRS-210023
Journal - Research Article
Healy, D., Mangin, D., & Lochhead, J. (2021). Development and persistence of patient-reported visual problems associated with serotonin reuptake inhibiting antidepressants. International Journal of Risk & Safety in Medicine. Advance online publication. doi: 10.3233/JRS-210018
Journal - Research Article
Hudson, B., Williman, J. A., Stamp, L. K., Alchin, J. S., Hooper, G. J., Mangin, D., Lennox Thompson, B. F., & Toop, L. (2021). Nortriptyline for pain in knee osteoarthritis in general practice: A double blind randomised controlled trial. British Journal of General Practice. Advance online publication. doi: 10.3399/bjgp.2020.0797
Journal - Research Article
Lewis, G., Marston, L., Duffy, L., Freemantle, N., Gilbody, S., Hunter, R., … Mangin, D., … Lewis, G. (2021). Maintenance or discontinuation of antidepressants in primary care. New England Journal of Medicine, 385, 1257-1267. doi: 10.1056/NEJMoa2106356
Journal - Research Article
Mangin, D., & Siu, H. Y.-H. (2021). Deprescribing antidepressants in older people: Breaking up can be hard to do. Senior Care Pharmacist, 36(5), 228-237. doi: 10.4140/TCP.n.2021.228
Journal - Research Article
Parkinson, L., Magin, P., Etherton-Beer, C., Naganathan, V., & Mangin, D. (2021). Engaging general practice and patients with AusTAPER, a pharmacist facilitated web-based deprescribing tool. Journal of Pharmacy Practice & Research. Advance online publication. doi: 10.1002/jppr.1713
Journal - Research Article
Thandi, M., Wong, S. T., Aponte-Hao, S., Grandy, M., Mangin, D., Singer, A., & Williamson, T. (2021). Strategies for working across Canadian practice-based research and learning networks (PBRLNs) in primary care: Focus on frailty. BMC Family Practice, 22, 220. doi: 10.1186/s12875-021-01573-y
Journal - Research Article
Dolovich, L., Gaber, J., Valaitis, R., Ploeg, J., Oliver, D., Richardson, J., Mangin, D., … Agarwal, G. (2020). Exploration of volunteers as health connectors within a multicomponent primary care-based program supporting self-management of diabetes and hypertension. Health & Social Care in the Community, 28(3), 734-746. doi: 10.1111/hsc.12904
Journal - Research Article
Mangin, D., Lawson, J., Adamczyk, K., & Guenter, D. (2020). Embedding "smart" disease coding within routine electronic medical record workflow: Prospective single-arm trial. JMIR Medical Informatics, 8(7), e16764. doi: 10.2196/16764
Journal - Research Article
Santaguida, P. L., Oliver, D., Gilsing, A., Lamarche, L., Griffith, L. E., Mangin, D., … Dolovich, L. (2020). Delphi consensus on core criteria set selecting among health-related outcome measures (HROM) in primary health care. Journal of Clinical Epidemiology, 127, 105-116. doi: 10.1016/j.jclinepi.2020.04.028
Journal - Research Article
Agarwal, G., Gaber, J., Richardson, J., Mangin, D., Ploeg, J., Valaitis, R., … Dolovich, L. (2019). Pilot randomized controlled trial of a complex intervention for diabetes self-management supported by volunteers, technology, and interprofessional primary health care teams. Pilot & Feasibility Studies, 5, 118. doi: 10.1186/s40814-019-0504-8
Journal - Research Article
Ailabouni, N., Mangin, D., & Nishtala, P. S. (2019). DEFEAT-polypharmacy: Deprescribing anticholinergic and sedative medicines feasibility trial in residential aged care facilities. International Journal of Clinical Pharmacy, 41, 167-178. doi: 10.1007/s11096-019-00784-9
Journal - Research Article
Bello, A. K., Ronksley, P. E., Tangri, N., Kurzawa, J., Osman, M. A., Singer, A., … Mangin, D., & Drummond, N. (2019). Prevalence and demographics of CKD in Canadian primary care practices: A cross-sectional study. Kidney International Reports, 4(4), 561-570. doi: 10.1016/j.ekir.2019.01.005
Journal - Research Article
Bello, A. K., Ronksley, P. E., Tangri, N., Kurzawa, J., Osman, M. A., Singer, A., … Mangin, D., & Drummond, N. (2019). Quality of chronic kidney disease management in Canadian primary care. JAMA Network Open, 2(9), e1910704. doi: 10.1001/jamanetworkopen.2019.10704
Journal - Research Article
Currie, O., Williman, J., Mangin, D., McKinnon-Gee, B., & Bridgford, P. (2019). Comparative risk of new-onset diabetes following commencement of antipsychotics in New Zealand: A population-based clustered multiple baseline time series design. BMJ Open, 9(2), e022984. doi: 10.1136/bmjopen-2018-022984
Journal - Research Article
Dolovich, L., Oliver, D., Lamarche, L., Thabane, L., Valaitis, R., Agarwal, G., … Mangin, D., … Price, D. (2019). Combining volunteers and primary care teamwork to support health goals and needs of older adults: A pragmatic randomized controlled trial. CMAJ, 191, E491-E500. doi: 10.1503/cmaj.181173
Journal - Research Article
Griffith, L. E., Gilsing, A., Mangin, D., Patterson, C., van den Heuvel, E., Sohel, N., … Raina, P. (2019). Multimorbidity frameworks impact prevalence and relationships with patient-important outcomes. Journal of the American Geriatrics Society, 67(8), 1632-1640. doi: 10.1111/jgs.15921
Journal - Research Article
Healy, D., Le Noury, J., & Mangin, D. (2019). Post-SSRI sexual dysfunction: Patient experiences of engagement with healthcare professionals. International Journal of Risk & Safety in Medicine, 30, 167-178. doi: 10.3233/JRS-191005
Journal - Research Article
Mangin, D., Parascandalo, J., Khudoyarova, O., Agarwal, G., Bismah, V., & Orr, S. (2019). Multimorbidity, eHealth and implications for equity: A cross-sectional survey of patient perspectives on eHealth. BMJ Open, 9, e023731. doi: 10.1136/bmjopen-2018-023731
Journal - Research Article
Mangin, D., Risdon, C., Lamarche, L., Langevin, J., Ali, A., Parascandalo, J., … Trimble, J. (2019). 'I think this medicine actually killed my wife': Patient and family perspectives on shared-decision-making to optimize medications and safety. Therapeutic Advances in Drug Safety, 10. doi: 10.1177/2042098619838796
Journal - Research Article
Millar, E., Gurney, J., Stanley, J., Stairmand, J., Davies, C., Semper, K., Dowell, A., Lawrenson, R., Mangin, D., & Sarfati, D. (2019). Pill for this and a pill for that: A cross-sectional survey of use and understanding of medication among adults with multimorbidity. Australasian Journal on Ageing, 38(2), 91-97. doi: 10.1111/ajag.12606
Journal - Research Article
Ploeg, J., Valaitis, R. K., Cleghorn, L., Yous, M.-L., Gaber, J., Agarwal, G., … Mangin, D., … Dolovich, L. (2019). Perceptions of older adults in Ontario, Canada on the implementation and impact of a primary care programme, Health Teams Advancing Patient Experience: Strengthening Quality (Health TAPESTRY): A descriptive qualitative study. BMJ Open, 9, e026257. doi: 10.1136/bmjopen-2018-026257
Journal - Research Article
Siu, H. Y.-H., Delleman, B., Langevin, J., Mangin, D., Howard, M., Fang, Q., … Chan, D. (2019). Demonstrating a technology-mediated intervention to support medication adherence in community-dwelling older adults in primary care: A feasibility study. Gerontology & Geriatric Medicine, 5. doi: 10.1177/2333721419845179
Journal - Research Article
Javadi, D., Lamarche, L., Avilla, E., Siddiqui, R., Gaber, J., Bhamani, M., … Mangin, D., & Dolovich, L. (2018). Feasibility study of goal setting discussions between older adults and volunteers facilitated by an eHealth application: Development of the Health TAPESTRY approach. Pilot & Feasibility Studies, 4, 184. doi: 10.1186/s40814-018-0377-2
Journal - Research Article
Mangin, D., Lawson, J., Cuppage, J., Shaw, E., Ivanyi, K., Davis, A., & Risdon, C. (2018). Legacy drug-prescribing patterns in primary care. Annals of Family Medicine, 16(6), 515-520. doi: 10.1370/afm.2315
Journal - Research Article
Stairmand, J., Gurney, J., Stanley, J., Millar, E., Davies, C., Semper, K., Dowell, A., Mangin, D., Lawrenson, R., & Sarfati, D. (2018). The impact of multimorbidity on people's lives: A cross-sectional survey. New Zealand Medical Journal, 131(1477), 78-90. Retrieved from https://www.nzma.org.nz/journal
Journal - Research Article
Ailabouni, N., Mangin, D., & Nishtala, P. S. (2017). Can deprescribing give what polypharmacy has taken away? Feasibility trial in residential aged care. Innovation in Aging, 1(Suppl. 1), 588-589. doi: 10.1093/geroni/igx004.2065
Journal - Research Article
Ailabouni, N., Mangin, D., & Nishtala, P. S. (2017). Deprescribing anticholinergic and sedative medicines: Protocol for a feasibility trial (DEFEAT-polypharmacy) in residential aged care facilities. BMJ Open, 7(4), e013800. doi: 10.1136/bmjopen-2016-013800
Journal - Research Article
Ailabouni, N., Mangin, D., Tordoff, J. M., & Nishtala, P. S. (2017). Do my patients need all their medicines? Registered nurses' views on deprescribing. Innovation in Aging, 1(Suppl. 1), 571. doi: 10.1093/geroni/igx004.2009
Journal - Research Article
Ailabouni, N., Tordoff, J., Mangin, D., & Nishtala, P. S. (2017). Do residents need all their medications? A cross-sectional survey of RNs' views on deprescribing and the role of clinical pharmacists. Journal of Gerontological Nursing, 43(10), 13-20. doi: 10.3928/00989134-20170914-05
Journal - Research Article
Signal, L., Semper, K., Stairmand, J., Davies, C., Millar, E., Dowell, T., … Mangin, D., & Sarfati, D. (2017). A walking stick in one hand and a chainsaw in the other: Patients’ perspectives of living with multimorbidity. New Zealand Medical Journal, 130(1455), 65-76. Retrieved from https://www.nzma.org.nz/journal
Journal - Research Article
Siu, H. Y.-H., Mangin, D., Howard, M., Price, D., & Chan, D. (2017). Developing and testing an electronic medication administration monitoring device for community dwelling seniors: A feasibility study. Pilot & Feasibility Studies, 3(1), 5. doi: 10.1186/s40814-016-0118-3
Journal - Research Article
Ailabouni, N. J., Nishtala, P. S., Mangin, D., & Tordoff, J. M. (2016). Challenges and enablers of deprescribing: A general practitioner perspective. PLoS ONE, 11(4), e0151066. doi: 10.1371/journal.pone.0151066
Journal - Research Article
Ailabouni, N. J., Nishtala, P. S., Mangin, D., & Tordoff, J. M. (2016). General practitioners' insight into deprescribing for the multimorbid older individual: A qualitative study. International Journal of Clinical Practice, 70(3), 261-276. doi: 10.1111/ijcp.12780
Journal - Research Article