Director, General Practice Research Group 
MB ChB DPH(Otago)
Director, McMaster University Sentinel and Information Collaboration (M.U.S.I.C.)
Email dee.mangin@otago.ac.nz
Research Interests
Dee Mangin is a New Zealand family physician who is currently Professor and Director of the Primary Care Research Group at the University of Otago, Christchurch. She is also the David Braley Nancy Gordon Chair in Family Medicine at McMaster University, Canada.
Her interests are rational prescribing, and the influences of science, policy and commerce on the nature of care.
Expertise spans generation of clinical evidence using randomised controlled trials, the effects of pharmaceutical company promotion to consumers and physicians, effective medicine use in older age, innovative models of general practice care and effective incorporation of evidence into patient-centered practice.
She has been a member of the Pharmaceutical and Therapeutic Products Advisory Committee.
Student Supervision
Nagham Ailabouni
Degree: PhD
Topic: De-prescribing discontinuation of unnecessary medicines in frail older people in New Zealand.
Supervisors: Dr June Tordoff, Professor Dee Mangin and Dr Prasad Nishtala
2014-15
Abigail Boyer
Topic: Evaluation of Pegasus Health's "Stop Smoking Support Options" Programme
Supervisors: Dr Lynley Cook and Associate Professor Dee Mangin
Sponsor: Pegasus Health (Charitable) Ltd
2012-13
Matthew Chamberlain
Topic: Psychological impact of September 2010 and subsequent earthquakes on Christchurch general practice patients.
Supervisors: Dee Mangin, Cerina Altenburg
Sponsor: The Royal New Zealand College of General Practitioners
Georgie Malcolm
Topic: Developing an evidence based pathway for UTI management in the primary/urgent care setting.
Supervisor: Dee Mangin
Co-supervisor: Louisa Sullivan
Sponsor: Pegasus Health
2010-11
Jasmine Gooda
Topic: Low dose antipsychotic use and metabolic side effects.
Supervisor: Dee Mangin
Sponsor: Pegasus Health
2009-10
Monica Johnson
Topic: Polypharmacy in the elderly – evaluating the Pill Pruner project.
Supervisors: Dee Mangin, Andrea Copeland, Nikki Ford
Sponsor: Pegasus Health
2008-09
Lauren Cumberpatch
Topic: The views of older adults on medicine use in treatment and prevention.
Supervisors: Dee Mangin & Kim Burgess
Sponsor: The Canterbury Health Care of the Elderly Education Trust
2007-08
Meagan McLeod ()
Topic: Comparison of the effectiveness of General Practice cervical screening systems.
Supervisor: Dee Mangin
Co-Supervisor Vivian Daley [Pegasus Health]
Sponsor: Pegasus Health IPA
2005-06
Charlotte Duncan
Topic: What are the drivers of PSA testing in Pegasus GPs?
Supervisors: Paul Corwin, Dee Mangin
Sponsor: Otago Theme Bursary, University of Otago
2004-05
Kris Wilson
Topic: A comparison of parental attitudes towards complementary and alternative medicines in children.
Supervisors: Dee Richards and Claire Dowson
Publications
Ailabouni, N., Mangin, D., & Nishtala, P. S. (2019). DEFEAT-polypharmacy: Deprescribing anticholinergic and sedative medicines feasibility trial in residential aged care facilities. International Journal of Clinical Pharmacy, 41, 167-178. doi: 10.1007/s11096-019-00784-9
Currie, O., Williman, J., Mangin, D., McKinnon-Gee, B., & Bridgford, P. (2019). Comparative risk of new-onset diabetes following commencement of antipsychotics in New Zealand: A population-based clustered multiple baseline time series design. BMJ Open, 9(2), e022984. doi: 10.1136/bmjopen-2018-022984
Duffy, L., Bacon, F., Clarke, C. S., Donkor, Y., Freemantle, N., Gilbody, S., … Mangin, D., … Lewis, G. (2019). A randomised controlled trial assessing the use of citalopram, sertraline, fluoxetine and mirtazapine in preventing relapse in primary care patients who are taking long-term maintenance antidepressants (ANTLER: ANTidepressants to prevent reLapse in dEpRession): Study protocol for a randomised controlled trial. Trials, 20(1), 319. doi: 10.1186/s13063-019-3390-8
Hudson, B., Toop, L., Williman, J., Hooper, G., Mangin, D., Alchin, J., Thompson, B., & Stamp, L. (2019). Nortriptyline in knee arthritis (nortika): A randomised controlled double blind trial of nortriptyline for pain in knee osteoarthritis. Arthritis & Rheumatology, 71(Suppl. 10), 2758. doi: 10.1002/art.41108
Ailabouni, N. J., Mangin, D., Gray, S., Marcum, Z., & Nishtala, P. (2019). To be successful or not to be: Retrospective analysis of two prescribing case studies. Journal of the American Geriatrics Society, 67(Suppl. 1), (pp. S185). doi: 10.1111/jgs.15898
Edited Book - Research
Ingham, T., Jones, B., on behalf of the Pharmacovigilance Ethics Advisory Group, including Smith, B., Mangin, D., & Moore, A. (Eds.). (2012). Medicine safety for New Zealanders: Ethical issue regarding the use of routinely collected data from general practice for pharmacovigilance (Draft ed.). Wellington, New Zealand: University Of Otago, 46p.
Mintzes, B., Mangin, D., & Hayes, L. (Eds.). (2009). Understanding and responding to pharmaceutical promotion: A practical guide [Working draft for pilot field testing]. World Health Organization & Health Action International. Retrieved from http://www.haiweb.org/11062009/drug-promotion-manual-CAP-3-090610.pdf
Chapter in Book - Research
Mangin, D. (2016). The contribution of primary care research to improving health services. In F. Goodyear-Smith & B. Mash (Eds.), International perspectives on primary care research. (pp. 67-72). Boca Raton, FL: CRC Press.
Healy, D., & Mangin, D. (2016). Does my bias look big in this? In F. Baylis & A. Ballantyne (Eds.), Clinical research involving pregnant women. (pp. 197-208). Springer. doi: 10.1007/978-3-319-26512-4_11
Mangin, D. (2015). A primary care perspective on prescribing for women. In M. Harrison-Woolrych (Ed.), Medicines for women. (pp. 403-432). Springer.
Mangin, D., & Heath, I. (2012). Polifarmácia [Polypharmacy]. In G. Gusso & J. M. C. Lopes (Eds.), Tratado de medicina de família e comunidadae [Textbook of family and community medicine]. (pp. 198-204). artmed.
Starfield, B., & Mangin, D. (2011). An international perspective on the basis of pay-for-performance. In S. Gillam & A. N. Siriwardena (Eds.), The quality and outcomes framework (QOF): Transforming general practice. (pp. 147-155). Abingdon, UK: Radcliffe.
Mangin, D. (2009). Promotion, professional practice and patient trust. In B. Mintzes, D. Mangin & L. Hayes (Eds.), Understanding and responding to pharmaceutical promotion: A practical guide [Working draft for pilot field testing]. (pp. 163-173). World Health Organization & Health Action International. Retrieved from http://www.haiweb.org/11062009/drug-promotion-manual-CAP-3-090610.pdf
Mintzes, B., Toop, L., & Mangin, D. (2009). Promotion to consumers: Responding to patient requests for advertised medicines. In B. Mintzes, D. Mangin & L. Hayes (Eds.), Understanding and responding to pharmaceutical promotion: A practical guide [Working draft for pilot field testing]. (pp. 81-104). World Health Organization & Health Action International. Retrieved from http://www.haiweb.org/11062009/drug-promotion-manual-CAP-3-090610.pdf
Chapter in Book - Other
Toop, L., & Mangin, D. (2013). Marketing of pharmaceuticals. In P. Joyce, G. Nicholls, K. Thomas & T. Wilkinson (Eds.), The Christchurch experience: 40 years of research and teaching. (pp. 177-182). Christchurch, New Zealand: University of Otago.
Journal - Research Article
Ailabouni, N., Mangin, D., & Nishtala, P. S. (2019). DEFEAT-polypharmacy: Deprescribing anticholinergic and sedative medicines feasibility trial in residential aged care facilities. International Journal of Clinical Pharmacy, 41, 167-178. doi: 10.1007/s11096-019-00784-9
Currie, O., Williman, J., Mangin, D., McKinnon-Gee, B., & Bridgford, P. (2019). Comparative risk of new-onset diabetes following commencement of antipsychotics in New Zealand: A population-based clustered multiple baseline time series design. BMJ Open, 9(2), e022984. doi: 10.1136/bmjopen-2018-022984
Mangin, D., Lawson, J., Cuppage, J., Shaw, E., Ivanyi, K., Davis, A., & Risdon, C. (2018). Legacy drug-prescribing patterns in primary care. Annals of Family Medicine, 16(6), 515-520. doi: 10.1370/afm.2315
Stairmand, J., Gurney, J., Stanley, J., Millar, E., Davies, C., Semper, K., Dowell, A., Mangin, D., Lawrenson, R., & Sarfati, D. (2018). The impact of multimorbidity on people's lives: A cross-sectional survey. New Zealand Medical Journal, 131(1477), 78-90. Retrieved from https://www.nzma.org.nz/journal
Signal, L., Semper, K., Stairmand, J., Davies, C., Millar, E., Dowell, T., … Mangin, D., & Sarfati, D. (2017). A walking stick in one hand and a chainsaw in the other: Patients’ perspectives of living with multimorbidity. New Zealand Medical Journal, 130(1455), 65-76. Retrieved from https://www.nzma.org.nz/journal
Ailabouni, N., Mangin, D., & Nishtala, P. S. (2017). Can deprescribing give what polypharmacy has taken away? Feasibility trial in residential aged care. Innovation in Aging, 1(Suppl. 1), 588-589. doi: 10.1093/geroni/igx004.2065
Ailabouni, N., Mangin, D., Tordoff, J. M., & Nishtala, P. S. (2017). Do my patients need all their medicines? Registered nurses' views on deprescribing. Innovation in Aging, 1(Suppl. 1), 571. doi: 10.1093/geroni/igx004.2009
Ailabouni, N., Mangin, D., & Nishtala, P. S. (2017). Deprescribing anticholinergic and sedative medicines: Protocol for a feasibility trial (DEFEAT-polypharmacy) in residential aged care facilities. BMJ Open, 7(4), e013800. doi: 10.1136/bmjopen-2016-013800
Siu, H. Y.-H., Mangin, D., Howard, M., Price, D., & Chan, D. (2017). Developing and testing an electronic medication administration monitoring device for community dwelling seniors: A feasibility study. Pilot & Feasibility Studies, 3(1), 5. doi: 10.1186/s40814-016-0118-3
Ailabouni, N., Tordoff, J., Mangin, D., & Nishtala, P. S. (2017). Do residents need all their medications? A cross-sectional survey of RNs' views on deprescribing and the role of clinical pharmacists. Journal of Gerontological Nursing, 43(10), 13-20. doi: 10.3928/00989134-20170914-05
Dolovich, L., Oliver, D., Lamarche, L., Agarwal, G., Carr, T., Chan, D., … Mangin, D., … Price, D. (2016). A protocol for a pragmatic randomized controlled trial using the Health Teams Advancing Patient Experience: Strengthening Quality (Health TAPESTRY) platform approach to promote person-focused primary healthcare for older adults. Implementation Science, 11, 49. doi: 10.1186/s13012-016-0407-5
Healy, D., Le Noury, J., & Mangin, D. (2016). Links between serotonin reuptake inhibition during pregnancy and neurodevelopmental delay/spectrum disorders: A systematic review of epidemiological and physiological evidence. International Journal of Risk & Safety in Medicine, 28(3), 125-141. doi: 10.3233/JRS-160726
Ailabouni, N. J., Nishtala, P. S., Mangin, D., & Tordoff, J. M. (2016). Challenges and enablers of deprescribing: A general practitioner perspective. PLoS ONE, 11(4), e0151066. doi: 10.1371/journal.pone.0151066
Mangin, D., Stephen, G., Bismah, V., & Risdon, C. (2016). Making patient values visible in healthcare: A systematic review of tools to assess patient treatment priorities and preferences in the context of multimorbidity. BMJ Open, 6(6), e010903. doi: 10.1136/bmjopen-2015-010903
Ailabouni, N. J., Nishtala, P. S., Mangin, D., & Tordoff, J. M. (2016). General practitioners' insight into deprescribing for the multimorbid older individual: A qualitative study. International Journal of Clinical Practice, 70(3), 261-276. doi: 10.1111/ijcp.12780
Mangin, D., & Heath, I. (2015). Multimorbidity and quaternary prevention (P4). Revista Brasileira de Medicina de Família e Comunidade [Brazilian Journal of Family and Community Medicine], 10(35), 1-5. doi: 10.5712/rbmfc10(35)1069
Hogan, C., Le Noury, J., Healy, D., & Mangin, D. (2014). One hundred and twenty cases of enduring sexual dysfunction following treatment. International Journal of Risk & Safety in Medicine, 26(2), 109-116. doi: 10.3233/JRS-140617
Brookwell, L., Hogan, C., Healy, D., & Mangin, D. (2014). Ninety-three cases of alcohol dependence following SSRI treatment. International Journal of Risk & Safety in Medicine, 26(2), 99-107. doi: 10.3233/JRS-140616
Healy, D., Howe, G., Mangin, D., & Le Noury, J. (2014). Sudden cardiac death & the reverse Dodo verdict. International Journal of Risk & Safety in Medicine, 26(2), 71-79. doi: 10.3233/JRS-140615
Hudson, B., Toop, L., Mangin, D., Brunton, C., Jennings, L., & Fletcher, L. (2013). Pandemic influenza A(H1N1)pdm09: Risk of infection in primary healthcare workers. British Journal of General Practice, 63(611), e416-e422. doi: 10.3399/bjgp13X668212
Healy, D., Mangin, D., & Antonuccio, D. (2013). Data based medicine and clinical judgement. International Journal of Risk & Safety in Medicine, 25(2), 111-121. doi: 10.3233/JRS-130588
Currie, O., Mangin, D., Williman, J., McKinnon-Gee, B., & Bridgford, P. (2013). The comparative risk of new-onset diabetes after prescription of drugs for cardiovascular risk prevention in primary care: A national cohort study. BMJ Open, 3(11), e003475 . doi: 10.1136/bmjopen-2013-003475
Mangin, D., Murdoch, D., Wells, J. E., Coughlan, E., Bagshaw, S., Corwin, P., Chambers, S., & Toop, L. (2012). Chlamydia trachomatis testing sensitivity in midstream compared with first-void urine specimens. Annals of Family Medicine, 10(1), 50-53. doi: 10.1370/afm.1323
Caplan, G. A., Sulaiman, N. S., Mangin, D. A., Ricauda, N. A., Wilson, A. D., & Barclay, L. (2012). A meta-analysis of "hospital in the home". Medical Journal of Australia, 197(9), 512-519. doi: 10.5694/mja12.10480
Starfield, B., Gérvas, J., & Mangin, D. (2012). Clinical care and health disparities. Annual Review of Public Health, 33(1), 89-106. doi: 10.1146/annurev-publhealth-031811-124528
Gill, E., & Mangin, D. (2011). Can general practitioners provide effective cardiovascular disease (CVD) prevention? Dreams and realities of CVD prevention. New Zealand Medical Journal, 124(1328). Retrieved from http://journal.nzma.org.nz/journal/124-1328/4506/content.pdf
Hudson, B., Toop, L., Mangin, D., & Pearson, J. (2011). Risk communication methods in hip fracture prevention: A randomised trial in primary care. British Journal of General Practice, 61(589), e469-e476. doi: 10.3399/bjgp11X588439
Starfield, B., & Mangin, D. (2010). An international perspective on the basis for payment for performance. Quality in Primary Care, 18(6), 399-404.
Mangin, D. (2010). All people over 75 years with a five-year CVD risk of ≥15% should be treated with statins unless specifically contraindicated: The 'no' case. Journal of Primary Health Care, 2(4), 333-335.
Garfinkel, D., & Mangin, D. (2010). Feasibility study of a systematic approach for discontinuation of multiple medications in older adults: Addressing polypharmacy. Archives of Internal Medicine, 170(18), 1648-1654. doi: 10.1001/archinternmed.2010.355
Healy, D., Mangin, D., & Mintzes, B. (2010). The ethics of randomized placebo controlled trials of antidepressants with pregnant women. International Journal of Risk & Safety in Medicine, 22(1), 7-16. doi: 10.3233/JRS-2010-0487
Wilson, K., Dowson, C., & Mangin, D. (2007). Prevalence of complementary and alternative medicine use in Christchurch, New Zealand: Children attending general practice versus paediatric outpatients. New Zealand Medical Journal, 120(1251). Retrieved from http://journal.nzma.org.nz/journal/120-1251/2464/content.pdf
Mangin, D., Sweeney, K., & Heath, I. (2007). Preventive health care in elderly people needs rethinking. BMJ, 335, 285-287. doi: 10.1136/bmj.39241.630741.BE1
Gill, E. A., Corwin, P. A., Mangin, D. A., & Sutherland, M. G. (2006). Diabetes care in rest homes in Christchurch, New Zealand. Diabetic Medicine, 23, 1252-1256.
Richards, D. A., Toop, L. J., Epton, M. J., McGeoch, G. R. B., Town, G. I., Wynn-Thomas, S. M. H., Dawson, R. D., Hlavac, M. C., Werno, A. M., & Abernethy, P. D. (2005). Home management of mild to moderately severe community-acquired pneumonia: A randomised controlled trial. Medical Journal of Australia, 183(5), 235-238.
Corwin, P., Toop, L., McGeoch, G., Than, M., Wynn-Thomas, S., Wells, J. E., Dawson, R., … Pithie, A., Chambers, S., Fletcher, L., & Richards, D. (2005). Randomised controlled trial of intravenous antibiotic treatment for cellulitis at home compared with hospital. British Medical Journal, 330(7483). Retrieved from http://www.bmj.com/cgi/reprint/330/7483/129
Richards, D., Toop, L., Chambers, S., & Fletcher, L. (2005). Response to antibiotics of women with symptoms of urinary tract infection but negative dipstick urine test results: Double blind randomised controlled trial. British Medical Journal, 331(7509). Retrieved from http://bmj.bmjjournals.com/cgi/content/abstract/331/7509/143
Mangin, D., Toop, L., Chambers, S., Ikram, R., & Harris, B. (2005). Increased rates of trimethoprim resistance in uncomplicated urinary tract infection: Cause for concern? New Zealand Medical Journal, 118(1225). Retrieved from http://journal.nzma.org.nz/journal/118-1225/1726/content.pdf
Richards, D. A., Toop, L. J., & Graham, P. J. (2003). Do clinical practice education groups result in sustained change in GP prescribing? Family Practice, 20(2), 199-206.
Richards, D., Toop, L., Brockway, K., Graham, S., McSweeney, B., MacLean, D., … Parsons, A. (2003). Improving the effectiveness of smoking cessation in primary care: Lessons learned. New Zealand Medical Journal, 116(1173). Retrieved from http://journal.nzma.org.nz/journal/116-1173/417/content.pdf
