Mutations; genetic analysis in bacteria; mobile genetic elements; genetic analysis of regulatory circuits; DNA cloning and sequencing in genetic analysis; comparative microbial genomics; genetics and evolution of viruses of eukaryotes.
GENE 221 provides foundation material on molecular and microbial genetics. Topics include mutation, gene transfer and genetic analysis in bacteria, DNA cloning and comparative genomics of bacteria, fungi and the HIV retrovirus. Discoveries and methodologies in microbial genetics underlie all aspects of modern biology, and therefore, this paper is directly relevant for students with an interest in any of the biological sciences. The lecture course is complemented by a laboratory course that includes four experiments that together give hands-on experience of many of the genetic principles that are discussed in the lectures.
|Paper title||Molecular and Microbial Genetics|
|Teaching period||First Semester|
|Domestic Tuition Fees (NZD)||$1,038.45|
|International Tuition Fees (NZD)||$4,680.00|
- CELS 191 and CHEM 191 and 36 further points
- GENE 211
- Recommended Preparation or Concurrent Study
- BIOC 221
- Schedule C
- Essential for students majoring in genetics or microbiology and appropriate for students majoring in biochemistry, molecular biotechnology and all other biological sciences.
- More information link
- View more information on the Genetics programme's website
- Teaching staff
- Convenor: Associate Professor Peter Fineran
(Department of Microbiology & Immunology)
Other teaching staff: Professor Iain Lamont (Department of Biochemistry), Professor Clive Ronson (Department of Microbiology & Immunology), Dr Gillian Mackay (Genetics Programme) and Associate Professor Russell Poulter (Department of Biochemistry)
- Paper Structure
- The lecture course is divided into 6 modules:
- Mutations - the basis of genetics
- Gene transfer and genetic analysis in bacteria
- Genetic analysis of regulatory circuits
- Comparative microbial genomics and evolution
- Comparative fungal genomics
- Genetics of HIV
- Teaching Arrangements
- There are six weeks of laboratory classes, one every second week, and students are assigned to one of four lab streams (Monday and Friday afternoons; first lab on the first Friday of semester).
- The recommended text book for GENE 221 is:
Introduction to Genetic Analysis (Griffiths, Wessler, Carroll, Doebley), 11th Edition. Earlier editions of this book are also satisfactory if you have access to a copy.
- Course outline
- View the information sheet for GENE 221
- Graduate Attributes Emphasised
- Global perspective, Interdisciplinary perspective, Scholarship, Critical thinking,
View more information about Otago's graduate attributes.
- Learning Outcomes
- The broad objectives of GENE 221 are to understand:
- The molecular basis and significance of mutation
- Classical genetics of bacteria
- The genetic approaches used in analysing gene regulation in bacteria
- DNA cloning as a tool for genetic analysis
- The use of comparative genomics in understanding the evolution of bacteria, yeast, other fungi and the HIV retrovirus