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    Overview

    An introduction to pharmaceutical discovery, design, manufacturing and drug action. Studies will examine the chemical properties of, and analytical techniques used in the pharmaceutical sciences and introduce how drugs act.

    PSCI 201 will introduce key aspects of pharmaceutical, bioorganic and medicinal chemistry. Students will gain an understanding of drug discovery and drug function, and be introduced to important chemical groups and transformations used in the design of drugs. Fundamental chromatographic and spectroscopic techniques used for purification, analysis and characterisation of drugs will also be taught.

    About this paper

    Paper title Pharmaceutical Chemistry
    Subject Pharmaceutical Science
    EFTS 0.1500
    Points 18 points
    Teaching period Semester 1 (On campus)
    Domestic Tuition Fees ( NZD ) $1,173.30
    International Tuition Fees Tuition Fees for international students are elsewhere on this website.
    Prerequisite
    CHEM 111 or CHEM 191
    Recommended Preparation
    PHSI 132 or PHSI 191
    Eligibility

    PSCI 201 builds on the foundations of first year chemistry, providing fundamental knowledge and skills in drug discovery and development. This paper will prepare students for 300-level papers in the BPharmSc degree and provide other students with a sound knowledge of pharmaceutical and medicinal chemistry that can complement BSc degrees with a chemistry, pharmacology, biochemistry or biology focus.

    Contact

    allan.gamble@otago.ac.nz

    Teaching staff

    Paper Co-ordinator:Associate Professor Allan Gamble

    Professor Natalie Hughes

    Associate Professor Arlene McDowell

    Dr Ailsa McGregor

    Paper Structure

    PSCI 201 will be taught through lectures, laboratories and workshops/tutorials covering the following general topics:

    • Introduction to important functional groups in drugs/pharmaceutics
    • Introduction to drug action
    • Spectroscopy used in pharmaceutical drug development and analysis
    • Purification and analysis of pharmaceutics
    • Introduction to peptide and polymer based pharmaceutic
    • Introduction to medicinal chemistry and prodrugs
    Textbooks

    Textbooks will be available through the library. Titles to be confirmed.

    Graduate Attributes Emphasised

    Global perspective, Interdisciplinary perspective, Lifelong learning, Scholarship, Communication, Critical thinking, Information literacy, Research, Self-motivation, Teamwork.
    View more information about Otago's graduate attributes.

    Learning Outcomes

    Students who successfully complete the paper will:

    1. Demonstrate an understanding of the drug discovery, design, and manufacture process.
    2. Demonstrate fundamental knowledge of pharmaceutical chemistry, which includes bioorganic and medicinal chemistry and basic pharmacology.
    3. Demonstrate basic fundamental knowledge in drug delivery and nanotechnology.
    4. Demonstrate fundamental knowledge of spectroscopic methods used in characterisation of small molecules and nanoparticles.
    5. Demonstrate fundamental knowledge of analytical methods used to purify, identify and quantify levels of pharmaceutics and formulations.
    6. Demonstrate competent practical skills for drug synthesis, purification, characterisation and quantitative analysis in pharmaceutical science.
    7. Communicate experimental data effectively in lab reports.

    Timetable

    Semester 1

    Location
    Dunedin
    Teaching method
    This paper is taught On Campus
    Learning management system
    Blackboard

    Lecture

    Stream Days Times Weeks
    Attend
    A1 Monday 08:00-08:50 9-13, 15-22
    Tuesday 08:00-08:50 9, 11, 13, 16-17, 20, 22
    Wednesday 13:00-13:50 10, 12, 15, 18-19
    Thursday 13:00-13:50 9-13, 16, 18-22

    Practical

    Stream Days Times Weeks
    Attend
    A1 Tuesday 14:00-16:50 11, 13, 16-17, 20, 22

    Tutorial

    Stream Days Times Weeks
    Attend
    A1 Thursday 14:00-15:50 15
    Friday 14:00-15:50 10, 12, 18-19, 21
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