In-depth exploration of critical decision points in the development of new medicines, from discovery and refinement, to preclinical assay selection, clinical trial design, and societal, ethical and regulatory challenges.
An in-depth exploration of critical decision points in the development of new medicines, from discovery and refinement, to preclinical assay selection, clinical trial design, and societal, ethical and regulatory challenges.
|Paper title||Drug Discovery and Development|
|Teaching period||Second Semester|
|Domestic Tuition Fees (NZD)||$1,080.30|
|International Tuition Fees (NZD)||$5,159.70|
- Two of (BIOC 192, CELS 191, CHEM 111, CHEM 191, HUBS 191, HUBS 192, BIOL 112, BIOL 123) and 54 further points
- Schedule C
Coure coordinator: Dr Lyn Wise (email@example.com)
- Teaching staff
Dr Lyn Wise
Dr Greg Giles
Prof. Paul Smith
Dr Belinda Cridge
- Paper Structure
- The Drug Pipeline
- Nature is the Best Medicine
- Drug Design
- Drugs, Biologics and Cell therapies
- Drug Safety
- Disease Models
- Clinical Trials
- Industry Research Contract: to extract, characterise and test the anti-microbial efficacy of a NZ-derived natural product.
- Drug Refinement Challenge: to use in silico tools to modify a drug structure and to predict changes in its safety and efficacy.
- Regulatory Panel: to simulate the processes involved in approving drugs for human use.
- Electronic Lab Book - 10%
- Dragons' Den Group Presentation - 10%
- Panel Participation 10%
- Mid-term test - 10%
- Final exam - 60%
No textbooks required.
- Graduate Attributes Emphasised
- Global perspective, Interdisciplinary perspective, Scholarship, Communication, Critical
thinking, Cultural understanding, Ethics, Information literacy, Research, Self-motivation,
View more information about Otago's graduate attributes.
- Learning Outcomes
Students who sucessfully complete this paper will:
- demonstrate an understanding of the critical steps and decision points in drug discovery and development
- explore the laboratory, computer and clinical models and tools used to assess drug safety and efficacy
- develop an awareness of the societal, ethical, and regulatory challenges associated with developing medicines
- demonstrate the principles of good laboratory practice and experimental design
- develop skills to identify, use and critically evaluate information from appropriate and reliable sources
- demonstrate an ability to communicate effectively, through written and oral means, to scientific and non-scientific audiences