Professor Sarah Hook
Position | Professor |
---|---|
Qualifications | BSc(Hons) PhD(Otago) |
Research summary | Vaccine formulation and delivery |
Teaching | Immunology and infectious diseases to undergraduate and postgraduate students |
Research
My area of interest is in the development and testing (physical, chemical and immunological) of novel vaccine formulations for the prevention and treatment of both communicable and non-communicable disease. My specific areas of interest are in the development of one-shot sustained release vaccines and in needle-free (transdermal or oral) vaccines for the treatment of tuberculosis and cancer.
My research focuses on:
- Sustained release vaccines
- Needle free vaccines
- Therapeutic cancer vaccines
- Identification and formulation of novel adjuvants
Professor Hook on Google Scholar
Publications
Dadhwal, S., Fairhall, J. M., Hook, S., & Gamble, A. B. (2020). Tetrafluoroaryl azide as an N-terminal capping group for click-to-dissolve diphenylalanine hydrogels. RSC Advances, 10(16), 9234-9244. doi: 10.1039/d0ra01013h
Fairhall, J. M., Murayasu, M., Dadhwal, S., Hook, S., & Gamble, A. B. (2020). Tuning activation and self-immolative properties of the bioorthogonal alkene-azide click-and-release strategy. Organic & Biomolecular Chemistry, 18, 4754-4762. doi: 10.1039/d0ob00936a
Naciute, M., Niemi, V., Kemp, R. A., & Hook, S. (2020). Lipid-encapsulated oral therapeutic peptide vaccines reduce tumour growth in an orthotopic mouse model of colorectal cancer. European Journal of Pharmaceutics & Biopharmaceutics, 153, 183-192. doi: 10.1016/j.ejpb.2020.04.020
Bobbala, S., & Hook, S. (2020). Vaccine implants: Current status and recent advancements. Emerging Topics in Life Sciences. Advance online publication. doi: 10.1042/etls20200164
Vu, H. T. H., Streck, S., Hook, S. M., & McDowell, A. (2019). Utilization of microfluidics for the preparation of polymeric nanoparticles for the antioxidant rutin: A comparison with bulk production. Pharmaceutical Nanotechnology, 7, 469-483. doi: 10.2174/2211738507666191019141049
Edited Book - Research
Foged, C., Rades, T., Perrie, Y., & Hook, S. (Eds.). (2015). Subunit vaccine delivery. New York: Springer. doi: 10.1007/978-1-4939-1417-3
Chapter in Book - Research
Rattanapak, T., Foged, C., & Hook, S. (2015). Transcutaneous immunization. In C. Foged, T. Rades, Y. Perrie & S. Hook (Eds.), Subunit vaccine delivery. (pp. 347-369). New York: Springer. doi: 10.1007/978-1-4939-1417-3
Hook, S., Slobbe, L., Chinn, N., Griffin, J. F. T., & Hesketh, J. B. (1995). Measuring cytokine responses to vaccination with live and killed BCG. In F. Griffin & G. de Lisle (Eds.), Tuberculosis in wildlife and domestic animals. (pp. 128-130). Dunedin: Otago University Press.
Lockhart, E., Slobbe, L., Hook, S., Griffin, F., & Mackintosh, C. G. (1995). The development of a new, multipurpose, animal model of tuberculosis. In F. Griffin & G. de Lisle (Eds.), Tuberculosis in wildlife and domestic animals. (pp. 158-160). Dunedin: Otago University Press.
Buchan, G. S., Lockhart, D., Slobbe, L., Chinn, N., Hook, S., Thomson, A., & Griffin, F. (1995). Vaccination: Can it be improved? In F. Griffin & G. de Lisle (Eds.), Tuberculosis in wildlife and domestic animals. (pp. 116-120). Dunedin: Otago University Press.
Journal - Research Article
Dadhwal, S., Fairhall, J. M., Hook, S., & Gamble, A. B. (2020). Tetrafluoroaryl azide as an N-terminal capping group for click-to-dissolve diphenylalanine hydrogels. RSC Advances, 10(16), 9234-9244. doi: 10.1039/d0ra01013h
Bobbala, S., & Hook, S. (2020). Vaccine implants: Current status and recent advancements. Emerging Topics in Life Sciences. Advance online publication. doi: 10.1042/etls20200164
Naciute, M., Niemi, V., Kemp, R. A., & Hook, S. (2020). Lipid-encapsulated oral therapeutic peptide vaccines reduce tumour growth in an orthotopic mouse model of colorectal cancer. European Journal of Pharmaceutics & Biopharmaceutics, 153, 183-192. doi: 10.1016/j.ejpb.2020.04.020
Fairhall, J. M., Murayasu, M., Dadhwal, S., Hook, S., & Gamble, A. B. (2020). Tuning activation and self-immolative properties of the bioorthogonal alkene-azide click-and-release strategy. Organic & Biomolecular Chemistry, 18, 4754-4762. doi: 10.1039/d0ob00936a
Vu, H. T. H., Streck, S., Hook, S. M., & McDowell, A. (2019). Utilization of microfluidics for the preparation of polymeric nanoparticles for the antioxidant rutin: A comparison with bulk production. Pharmaceutical Nanotechnology, 7, 469-483. doi: 10.2174/2211738507666191019141049
von Halling Laier, C., Gibson, B., Moreno, J. A. S., Rades, T., Hook, S., Nielsen, L. H., & Boisen, A. (2019). Microcontainers for protection of oral vaccines, in vitro and in vivo evaluation. Journal of Controlled Release, 294, 91-101. doi: 10.1016/j.jconrel.2018.11.030
Dadhwal, S., Fairhall, J. M., Goswami, S. K., Hook, S., & Gamble, A. B. (2019). Alkene-azide 1,3-dipolar cycloaddition as a trigger for ultrashort peptide hydrogel dissolution. Chemistry: An Asian Journal, 14, 1143-1150. doi: 10.1002/asia.201801184
Matikonda, S. S., Fairhall, J. M., Fiedler, F., Sanhajariya, S., Tucker, R. A. J., Hook, S., Garden, A. L., & Gamble, A. B. (2018). Mechanistic evaluation of bioorthogonal decaging with trans-cyclooctene: The effect of fluorine substituents on aryl azide reactivity and decaging from the 1,2,3-triazoline. Bioconjugate Chemistry, 29(2), 324-334. doi: 10.1021/acs.bioconjchem.7b00665
Cooper, A. G., Oyagawa, C. R. M., Manning, J. J., Singh, S., Hook, S., Grimsey, N. L., Glass, M., Tyndall, J. D. A., & Vernall, A. J. (2018). Development of selective, fluorescent cannabinoid type 2 receptor ligands based on a 1,8-naphthyridin-2-(1H)-one-3-carboxamide scaffold. MedChemComm, 9(12), 2055-2067. doi: 10.1039/c8md00448j
Bobbala, S., Gibson, B., Gamble, A. B., McDowell, A., & Hook, S. (2018). Poloxamer 407-chitosan grafted thermoresponsive hydrogels achieve synchronous and sustained release of antigen and adjuvant from single-shot vaccines. Immunology & Cell Biology, 96(6), 656-665. doi: 10.1111/imcb.12031
Cooper, A. G., MacDonald, C., Glass, M., Hook, S., Tyndall, J. D. A., & Vernall, A. J. (2018). Alkyl indole-based cannabinoid type 2 receptor tools: Exploration of linker and fluorophore attachment. European Journal of Medicinal Chemistry, 145, 770-789. doi: 10.1016/j.ejmech.2017.11.076
Vu, H. T. H., Hook, S. M., Siqueira, S. D., Müllertz, A., Rades, T., & McDowell, A. (2018). Are phytosomes a superior nanodelivery system for the antioxidant rutin? International Journal of Pharmaceutics, 548(1), 82-91. doi: 10.1016/j.ijpharm.2018.06.042
Kaneko, K., McDowell, A., Ishii, Y., & Hook, S. (2018). Characterization and evaluation of stabilized particulate formulations as therapeutic oral vaccines for allergy. Journal of Liposome Research, 28(4), 296-304. doi: 10.1080/08982104.2017.1370472
Cooper, A., Singh, S., Hook, S., Tyndall, J. D. A., & Vernall, A. J. (2017). Chemical tools for studying lipid-binding class A G protein-coupled receptors. Pharmacological Reviews, 69(3), 316-353. doi: 10.1124/pr.116.013243
Umair, S., Pernthaner, A., Deng, Q., Gibson, B., Hook, S., & Heath, D. (2017). Preliminary evaluation of a thermosensitive chitosan hydrogel for Echinococcus granulosus vaccine delivery. Veterinary Parasitology, 236, 117-120. doi: 10.1016/j.vetpar.2017.02.007
Even, M.-P., Bobbala, S., Gibson, B., Hook, S., Winter, G., & Engert, J. (2017). Twin-screw extruded lipid implants containing TRP2 peptide for tumour therapy. European Journal of Pharmaceutics & Biopharmaceutics, 114, 79-87. doi: 10.1016/j.ejpb.2016.12.033
Matikonda, S. S., Fairhall, J. M., Tyndall, J. D. A., Hook, S., & Gamble, A. B. (2017). Stability, kinetic, and mechanistic investigation of 1,8-self-immolative cinnamyl ether spacers for controlled release of phenols and generation of resonance and inductively stabilized methides. Organic Letters, 19(3), 528-531. doi: 10.1021/acs.orglett.6b03695
Kaneko, K., McDowell, A., Ishii, Y., & Hook, S. (2017). Liposomal α-galactosylceramide is taken up by gut-associated lymphoid tissue and stimulates local and systemic immune responses. Journal of Pharmacy & Pharmacology, 69(12), 1724-1735. doi: 10.1111/jphp.12814
Azhari, H., Strauss, M., Hook, S., Boyd, B. J., & Rizwan, S. B. (2016). Stabilising cubosomes with Tween 80 as a step towards targeting lipid nanocarriers to the blood-brain barrier. European Journal of Pharmaceutics & Biopharmaceutics, 104, 148-155. doi: 10.1016/j.ejpb.2016.05.001
Neumann, S., Shirley, S. A., Kemp, R. A., & Hook, S. M. (2016). Improved antitumor activity of a therapeutic melanoma vaccine through the use of the dual COX-2/5-LO inhibitor licofelone. Frontiers in Immunology, 7(537), 537. doi: 10.3389/fimmu.2016.00537
Bobbala, S., & Hook, S. (2016). Is there an optimal formulation and delivery strategy for subunit vaccines? Pharmaceutical Research, 33(9), 2078-2097. doi: 10.1007/s11095-016-1979-0
Bobbala, S., Tamboli, V., McDowell, A., Mitra, A. K., & Hook, S. (2016). Novel injectable pentablock copolymer based thermoresponsive hydrogels for sustained release vaccines. AAPS Journal, 18(1), 261-269. doi: 10.1208/s12248-015-9843-4
Gauld, N. J., Braganza, C., Babalola, O. O., Huynh, T. T., & Hook, S. M. (2016). Reasons for use and non-use of the pertussis vaccine during pregnancy: An interview study. Journal of Primary Health Care, 8(4), 344-350. doi: 10.1071/HC15049
Highton, A. J., Girardin, A., Bell, G. M., Hook, S. M., & Kemp, R. A. (2016). Chitosan gel vaccine protects against tumour growth in an intracaecal mouse model of cancer by modulating systemic immune responses. BMC Immunology, 17, 39. doi: 10.1186/s12865-016-0178-4
Subharat, S., Shu, D., Zheng, T., Buddle, B. M., Kaneko, K., Hook, S., … Wedlock, D. N. (2016). Vaccination of sheep with a methanogen protein provides insight into levels of antibody in saliva needed to target ruminal methanogens. PLoS ONE, 11(7), e0159861. doi: 10.1371/journal.pone.0159861
Kaneko, K., McDowell, A., Ishii, Y., & Hook, S. (2015). Selective quantitation of the incorporation of the immunomodulator α-galactosylceramide in liposomes using LC-MS/MS. International Journal of Mass Spectrometry, 392, 96-101. doi: 10.1016/j.ijms.2015.09.016
Neumann, S., Young, K., Compton, B., Anderson, R., Painter, G., & Hook, S. (2015). Synthetic TRP2 long-peptide and α-galactosylceramide formulated into cationic liposomes elicit CD8+ T-cell responses and prevent tumour progression. Vaccine, 33, 5838-5844. doi: 10.1016/j.vaccine.2015.08.083
Scherließ, R., Mönckedieck, M., Young, K., Trows, S., Buske, S., & Hook, S. (2015). First in vivo evaluation of particulate nasal dry powder vaccine formulations containing ovalbumin in mice. International Journal of Pharmaceutics, 479(2), 408-415. doi: 10.1016/j.ijpharm.2015.01.015
Kojarunchitt, T., Baldursdottir, S., Dong, Y.-D., Boyd, B. J., Rades, T., & Hook, S. (2015). Modified thermoresponsive Poloxamer 407 and chitosan sol-gels as potential sustained-release vaccine delivery systems. European Journal of Pharmaceutics & Biopharmaceutics, 89, 74-81. doi: 10.1016/j.ejpb.2014.11.026
Engelke, L., Winter, G., Hook, S., & Engert, J. (2015). Recent insights into cutaneous immunization: How to vaccinate via the skin. Vaccine, 33, 4663-4674. doi: 10.1016/j.vaccine.2015.05.012
Bobbala, S., McDowell, A., & Hook, S. (2015). Quantitation of the immunological adjuvants, monophosphoryl lipid A and Quil A in poly (lactic-co-glycolic acid) nanoparticles using high performance liquid chromatography with evaporative light scattering detection. Journal of Chromatography B, 975, 45-51. doi: 10.1016/j.jchromb.2014.11.006
Greatrex, B. W., Daines, A. M., Hook, S., Lenz, D. H., McBurney, W., Rades, T., & Rendle, P. M. (2015). Synthesis, formulation, and adjuvanticity of monodesmosidic saponins with olenanolic acid, hederagenin and gypsogenin aglycones, and some C-28 ester derivatives. ChemistryOpen, 4(6), 740-755. doi: 10.1002/open.201500149
Even, M.-P., Bobbala, S., Kok, L. K., Hook, S., Winter, G., & Engert, J. (2015). Impact of implant composition of twin-screw extruded lipid implants on the release behavior. International Journal of Pharmaceutics, 493, 102-110. doi: 10.1016/j.ijpharm.2015.06.052
Liau, J. J., Hook, S., Prestidge, C. A., & Barnes, T. J. (2015). A lipid based multi-compartmental system: Liposomes-in-double emulsion for oral vaccine delivery. European Journal of Pharmaceutics & Biopharmaceutics, 97, 15-21. doi: 10.1016/j.ejpb.2015.09.018
Highton, A. J., Kojarunchitt, T., Girardin, A., Hook, S., & Kemp, R. A. (2015). Chitosan hydrogel vaccine generates protective CD8 T cell memory against mouse melanoma. Immunology & Cell Biology, 93, 634-640. doi: 10.1038/icb.2015.14
Hubert, M., Larsen, D. S., Hayman, C. M., Rades, T., & Hook, S. (2014). Physical characterization of synthetic phosphatidylinositol dimannosides and analogues in binary systems with phosphatidylcholine. Molecular Pharmaceutics, 11(3), 913-921. doi: 10.1021/mp400588y
Even, M.-P., Young, K., Winter, G., Hook, S., & Engert, J. (2014). In vivo investigation of twin-screw extruded lipid implants for vaccine delivery. European Journal of Pharmaceutics & Biopharmaceutics, 87(2), 338-346. doi: 10.1016/j.ejpb.2014.02.014
Neumann, S., Burkert, K., Kemp, R., Rades, T., Dunbar, P. R., & Hook, S. (2014). Activation of the NLRP3 inflammasome is not a feature of all particulate vaccine adjuvants. Immunology & Cell Biology, 92, 535-542. doi: 10.1038/icb.2014.21
Rattanapak, T., Birchall, J. C., Young, K., Kubo, A., Fujimori, S., Ishii, M., & Hook, S. (2014). Dynamic visualization of dendritic cell-antigen interactions in the skin following transcutaneous immunization. PLoS ONE, 9(2), e89503. doi: 10.1371/journal.pone.0089503
Rizwan, S. B., McBurney, W. T., Young, K., Hanley, T., Boyd, B. J., Rades, T., & Hook, S. (2013). Cubosomes containing the adjuvants imiquimod and monophosphoryl lipid A stimulate robust cellular and humoral immune responses. Journal of Controlled Release, 165(1), 16-21. doi: 10.1016/j.jconrel.2012.10.020
Scherließ, R., Buske, S., Young, K., Weber, B., Rades, T., & Hook, S. (2013). In vivo evaluation of chitosan as an adjuvant in subcutaneous vaccine formulations. Vaccine, 31(42), 4812-4819. doi: 10.1016/j.vaccine.2013.07.081
Rattanapak, T., Birchall, J., Young, K., Ishii, M., Meglinski, I., Rades, T., & Hook, S. (2013). Transcutaneous immunization using microneedles and cubosomes: Mechanistic investigations using Optical Coherence Tomography and two-photon microscopy. Journal of Controlled Release, 172(3), 894-903. doi: 10.1016/j.jconrel.2013.08.018
Hubert, M., Compton, B. J., Hayman, C. M., Larsen, D. S., Painter, G. F., Rades, T., & Hook, S. (2013). Physicochemical and biological characterization of synthetic phosphatidylinositol dimannosides and analogues. Molecular Pharmaceutics, 10(5), 1928-1939. doi: 10.1021/mp300707a
Kamali, T., Doronin, A., Rattanapak, T., Hook, S., & Meglinski, I. (2012). Assessment of transcutaneous vaccine delivery by optical coherence tomography. Laser Physics Letters, 9(8), 607-610. doi: 10.7452/lapl.201210046
Rattanapak, T., Young, K., Rades, T., & Hook, S. (2012). Comparative study of liposomes, transfersomes, ethosomes and cubosomes for transcutaneous immunisation: Characterisation and in vitro skin penetration. Journal of Pharmacy & Pharmacology, 64(11), 1560-1569. doi: 10.1111/j.2042-7158.2012.01535.x
Gordon, S., Young, K., Wilson, R., Rizwan, S., Kemp, R., Rades, T., & Hook, S. (2012). Chitosan hydrogels containing liposomes and cubosomes as particulate sustained release vaccine delivery systems. Journal of Liposome Research, 22(3), 193-204. doi: 10.3109/08982104.2011.637502
Kojarunchitt, T., Hook, S., Rizwan, S., Rades, T., & Baldursdottir, S. (2011). Development and characterisation of modified poloxamer 407 thermoresponsive depot systems containing cubosomes. International Journal of Pharmaceutics, 408(1-2), 20-26. doi: 10.1016/j.ijpharm.2011.01.037
Rizwan, S. B., Assmus, D., Boehnke, A., Hanley, T., Boyd, B. J., Rades, T., & Hook, S. (2011). Preparation of phytantriol cubosomes by solvent precursor dilution for the delivery of protein vaccines. European Journal of Pharmaceutics & Biopharmaceutics, 79(1), 15-22. doi: 10.1016/j.ejpb.2010.12.034
Hook, S. M., Phipps-Green, A. J., Faiz, F., McNoe, L., McKinney, C., Hollis-Moffatt, J. E., & Merriman, T. R. (2011). Smad2: A candidate gene for the murine autoimmune diabetes locus Idd21.1. Journal of Clinical Endocrinology & Metabolism, 96(12), E2072-E2077. doi: 10.1210/jc.2011-0463
Rizwan, S. B., Boyd, B. J., Rades, T., & Hook, S. (2010). Bicontinuous cubic liquid crystals as sustained delivery systems for peptides and proteins. Expert Opinion on Drug Delivery, 7(10), 1133-1144. doi: 10.1517/17425247.2010.515584
Gordon, S., Teichmann, E., Young, K., Finnie, K., Rades, T., & Hook, S. (2010). In vitro and in vivo investigation of thermosensitive chitosan hydrogels containing silica nanoparticles for vaccine delivery. European Journal of Pharmaceutical Sciences, 41(2), 360-368. doi: 10.1016/j.ejps.2010.07.004
Myschik, J., Rades, T., & Hook, S. (2009). Advances in lipid-based subunit vaccine formulations. Current Immunology Reviews, 5(1), 42-48.
Ferderber, K., Hook, S., & Rades, T. (2009). Phosphatidyl choline-based colloidal systems for dermal and transdermal drug delivery. Journal of Liposome Research, 19(4), 267-277. doi: 10.3109/08982100902814006
Greatrex, B. W., Brodie, S. J., Furneaux, R. H., Hook, S. M., McBurney, W. T., Painter, G. F., Rades, T., & Rendle, P. M. (2009). The synthesis and immune stimulating action of mannose-capped lysine-based dendrimers. Tetrahedron, 65(15), 2939-2950. doi: 10.1016/j.tet.2009.02.018
Daines, A. M., Greatrex, B. W., Hayman, C. M., Hook, S. M., McBurney, W. T., Rades, T., … Sims, I. M. (2009). Mannosylated saponins based on oleanolic and glycyrrhizic acids. Towards synthetic colloidal antigen delivery systems. Bioorganic & Medicinal Chemistry, 17(14), 5207-5218. doi: 10.1016/j.bmc.2009.05.043
Braund, R., Hook, S. M., Greenhill, N., & Medlicott, N. J. (2009). Distribution of fibroblast growth factor-2 (FGF-2) within model excisional wounds following topical application. Journal of Pharmacy & Pharmacology, 61(2), 193-200. doi: 10.1211/jpp/61.02.0008
Graf, A., Rades, T., & Hook, S. M. (2009). Oral insulin delivery using nanoparticles based on microemulsions with different structure-types: Optimisation and in vivo evaluation. European Journal of Pharmaceutical Sciences, 37(1), 53-61. doi: 10.1016/j.ejps.2008.12.017
Rizwan, S. B., Hanley, T., Boyd, B. J., Rades, T., & Hook, S. (2009). Liquid crystalline systems of phytantriol and glyceryl monooleate containing a hydrophilic protein: Characterisation, swelling and release kinetics. Journal of Pharmaceutical Sciences, 98(11), 4191-4204. doi: 10.1002/jps.21724
Myschik, J., McBurney, W. T., Hennessy, T., Phipps-Green, A., Rades, T., & Hook, S. (2008). Immunostimulatory biodegradable implants containing the adjuvant Quil-A - Part II: In vivo evaluation. Journal of Drug Targeting, 16(3), 224-232. doi: 10.1080/10611860701848886
Gordon, S., Saupe, A., McBurney, W., Rades, T., & Hook, S. (2008). Comparison of chitosan nanoparticles and chitosan hydrogels for vaccine delivery. Journal of Pharmacy & Pharmacology, 60, 1591-1600. doi: 10.1211/jpp/60.12.0004
Myschik, J., Eberhardt, F., Rades, T., & Hook, S. (2008). Immunostimulatory biodegradable implants containing the adjuvant Quil-A - Part I: Physicochemical characterisation. Journal of Drug Targeting, 16(3), 213-223. doi: 10.1080/10611860701848860
Graf, A., Ablinger, E., Peters, S., Zimmer, A., Hook, S., & Rades, T. (2008). Microemulsions containing lecithin and sugar-based surfactants: Nanoparticle templates for delivery of proteins and peptides. International Journal of Pharmaceutics, 350, 351-360. doi: 10.1016/j.ijpharm.2007.08.053
McBurney, W. T., Lendemans, D. G., Myschik, J., Hennessy, T., Rades, T., & Hook, S. (2008). In vivo activity of cationic immune stimulating complexes (PLUSCOMs). Vaccine, 26, 4549-4556. doi: 10.1016/j.vaccine.2008.06.024
Myschik, J., McBurney, W. T., Rades, T., & Hook, S. (2008). Immunostimulatory lipid implants containing Quil-A and DC-cholesterol. International Journal of Pharmaceutics, 363, 91-98. doi: 10.1016/j.ijpharm.2008.07.014
Myschik, J., McBurney, W. T., Hennessy, T., Rades, T., & Hook, S. (2008). Immunogenicity of lipid sustained release implants containing imiquimod, α-galactosylceramide, or Quil-A. Pharmazie, 63(9), 686-692. doi: 10.1691/ph.2008.8072
Graf, A., Jack, K. S., Whittaker, A. K., Hook, S. M., & Rades, T. (2008). Protein delivery using nanoparticles based on microemulsions with different structure-types. European Journal of Pharmaceutical Sciences, 33, 434-444.
Krauel, K., Girvan, L., Hook, S., & Rades, T. (2007). Characterisation of colloidal drug delivery systems from the naked eye to Cryo-FESEM. Micron, 38, 796-803.
Lendemans, D. G., Egert, A. M., Hook, S., & Rades, T. (2007). Cage-like complexes formed by DOTAP, Quil-A and cholesterol. International Journal of Pharmaceutics, 332, 192-195.
Braund, R., Hook, S., & Medlicott, N. J. (2007). The role of topical growth factors in chronic wounds. Current Drug Delivery, 4(3), 195-204. doi: 10.2174/156720107781023857
Demana, P. H., Davies, N. M., Hook, S., & Rades, T. (2007). Analysis of Quil A-phospholipid mixtures using drift spectroscopy. International Journal of Pharmaceutics, 342, 49-61.
Rizwan, S. B., Dong, Y.-D., Boyd, B. J., Rades, T., & Hook, S. (2007). Characterisation of bicontinuous cubic liquid crystalline systems of phytantriol and water using cryo field emission scanning electron microscopy (cryo FESEM). Micron, 38, 478-485. doi: 10.1016/j.micron.2006.08.003
Boyd, B. J., Rizwan, S. B., Dong, Y.-D., Hook, S., & Rades, T. (2007). Self-assembled geometric liquid-crystalline nanoparticles imaged in three dimensions: Hexosomes are not necessarily flat hexagonal prisms. Langmuir, 23(25), 12461-12464. doi: 10.1021/la7029714
White, K., Rades, T., Kearns, P., Toth, I., & Hook, S. (2006). Immunogenicity of liposomes containing lipid core peptides and the adjuvant Quil A. Pharmaceutical Research, 23(7), 1473-1481.
Lendemans, D. G., Egert, A. M., Myschik, J., Hook, S., & Rades, T. (2006). On the dilution behaviour of immuno-stimulating complexes (ISCOMs). Pharmazie, 61(8), 689-695.
Weir, C., McNeill, A., Hook, S., Harvie, M., La Flamme, A. C., Le Gros, G., & Bäckström, B. T. (2006). Critical role of preproenkephalin in experimental autoimmune encephalomyelitis. Journal of Neuroimmunology, 179, 18-25.
Grimwood, K., Huang, Q. S., Cohet, C., Gosling, I. A., Hook, S. M., Teele, D. W., … Leadbitter, P., & Lennon, D. R. (2006). Rotavirus hospitalisation in New Zealand children under 3 years of age. Journal of Paediatrics & Child Health, 42(4), 196-203. doi: 10.1111/j.1440-1754.2006.00829.x
Krauel, K., Graf, A., Hook, S. M., Davies, N. M., & Rades, T. (2006). Preparation of poly (alkylcyanoacrylate) nanoparticles by polymerization of water-free microemulsions. Journal of Microencapsulation, 23(5), 499-512.
Myschik, J., Lendemans, D. G., McBurney, W. T., Demana, P. H., Hook, S., & Rades, T. (2006). On the preparation, microscopic investigation and application of ISCOMs. Micron, 37, 724-734.
Saupe, A., McBurney, W., Rades, T., & Hook, S. (2006). Immunostimulatory colloidal delivery systems for cancer vaccines. Expert Opinion on Drug Delivery, 3(3), 345-354.
White, K. L., Rades, T., Furneaux, R. H., Tyler, P. C., & Hook, S. (2006). Mannosylated liposomes as antigen delivery vehicles for targeting to dendritic cells. Journal of Pharmacy & Pharmacology, 58, 729-737.
Hook, S., Chan, L., Cutfield, H., Dean, R., Keir, A., Gordon, G., & Norris, P. (2005). Immunisation knowledge and beliefs of health science and non-health science students at the University of Otago. New Zealand Family Physician, 32(6), 394-398.
Chen, Y. E., Beasley, S., Grimwood, K., and the New Zealand Rotavirus Study Group, including Hook, S. (2005). Intussusception and rotavirus associated hospitalisation in New Zealand. Archives of Disease in Childhood, 90, 1077-1081. doi: 10.1136/adc.2005.074104
Lendemans, D. G., Myschik, J., Hook, S., & Rades, T. (2005). Cationic cage-like complexes formed by DC-cholestrol, Quil-A, and phospholipid. Journal of Pharmaceutical Sciences, 94(8), 1794-1807.
Krauel, K., Davies, N. M., Hook, S., & Rades, T. (2005). Using different structure types of microemulsions for the preparation of poly(alkylcyanoacrylate) nanoparticles by interfacial polymerization. Journal of Controlled Release, 106(1-2), 76-87. doi: 10.1016/j.jconrel.2005.04.013
Hollis-Moffatt, J. E., Hook, S. M., & Merriman, T. R. (2005). Colocalization of mouse autoimmune diabetes loci Idd21.1 and Idd21.2 with IddM6 (Human) and Iddm3 (Rat) [Brief Genetics Report]. Diabetes, 54, 2820-2825.
Armstrong, D. S., Hook, S. M., Jamsen, K. M., Nixon, G. M., Carzino, R., Carlin, J. B., … Grimwood, K. (2005). Lower airway inflammation in infants with cystic fibrosis detected by newborn screening. Pediatric Pulmonology, 40, 500-510.
Demana, P. H., Davies, N. M., Hook, S., & Rades, T. (2005). Quil A-lipid powder formulations releasing ISCOMs and related colloidal stuctures upon hydration. Journal of Controlled Release, 103, 45-59.
Lendemans, D. G., Myschik, J., Hook, S., & Rades, T. (2005). Immuno-stimulating complexes prepared by ethanol injection. Journal of Pharmacy & Pharmacology, 57, 729-733.
White, K., Kearns, P., Toth, I., & Hook, S. (2004). Increased adjuvant activity of minimal CD8 T cell peptides incorporated into lipid-core-peptides. Immunology & Cell Biology, 82, 517-522. doi: 10.1111/j.0818-9641.2004.01269.x
Marsland, B. J., Harris, N. L., Camberis, M., Kopf, M., Hook, S. M., & Le Gros, G. (2004). Bystander suppression of allergic airway inflammation by lung resident memory CD8+ T cells. PNAS, 101(16), 6116-6121.
Demana, P. H., Fehske, C., White, K., Rades, T., & Hook, S. (2004). Effect of incorporation of the adjuvant Quil A on structure and immune stimulatory capacity of liposomes. Immunology & Cell Biology, 82, 547-554.
Hook, S. M., Camberis, M., Prout, M., & Le Gros, G. (2003). Absence of preproenkephalin increases the threshold for T cell activation. Journal of Neuroimmunology, 140, 61-68.
Hook, S. M., & Le Gros, G. (2002). Immunomodulatory effects of preproenkephalin. Current Opinions in European Medicine, 3, 68-80.
Hook, S. M., Prout, M., Camberis, M., Konig, M., Zimmer, A., & Le Gros, G. (2000). Th2 dependent airway eosinophilia is regulated by preproenkephalin. Journal of Neuroimmunology, 107, 59-65.
Hook, S., Cheng, P., Holloway, J. W., Riley, G., Sawyer, G., Le Gros, G., & Beasley, R. (1999). Analysis of two IL-4 promoter polymorphisms in a cohort of atopic and asthmatic subjects. Experimental & Clinical Immunogenetics, 16(1), 33-35. doi: 10.1159/000019094