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Health Sciences staff profiles

Dr May Mei

PositionSenior Lecturer
DepartmentDepartment of Oral Rehabilitation
QualificationsBDS MDS PhD
Research summaryCariology, Oral Microbiology
TeachingCariology, Operative Dentistry in undergraduate and postgraduate level
Memberships
  • Membership of International Association for Dental Research (IADR)
  • Membership of Academy of Dental Materials (ADM)
  • Dr Mei served as a symposium/lunch & learning organizer in Cariology Research Group IADR in 2014-2016
ClinicalRestorative Dentistry / Prosthodontics

Research

Dr Mei's research focuses on Cariology:

  1. The effect of silver diamine fluoride on mineralized tissue, collagen and biofilm
  2. Developing bioactive materials to prevent and arrest caries

Dr Mei's Scopus H index is 19 to date. Dr Mei is sitting on the Editorial Board of Archives of Oral Biology.

Publications

Won, J., Guan, G., Mei, L., Ma, T., Lai, Y., Zafar, S., Mei, M. L., & Thomson, W. M. (2021). A multicenter study of dental curricula in Asia/Pacific nations: The views and experiences of final-year dental students. Journal of Dental Education. Advance online publication. doi: 10.1002/jdd.12515

Zhang, J., Zhao, I. S., Yu, O. Y., Li, Q., Mei, M. L., Zhang, C., & Chung, C. H. (2021). Layer-by-layer self-assembly polyelectrolytes loaded with cyclic adenosine monophosphate enhances the osteo/odontogenic differentiation of stem cells from apical papilla. Journal of Biomedical Materials Research Part A, 109, 207-218. doi: 10.1002/jbm.a.37017

Dai, L. L., Nudelman, F., Chu, C. H., Lo, E. C. M., & Mei, M. L. (2021). The effects of strontium-doped bioactive glass and fluoride on hydroxyapatite crystallization. Journal of Dentistry. Advance online publication. doi: 10.1016/j.jdent.2021.103581

Dai, L. L., Mei, M. L., Chu, C. H., & Lo, E. C. M. (2021). Remineralizing effect of a new strontium-doped bioactive glass and fluoride on demineralized enamel and dentine. Journal of Dentistry, 103633. Advance online publication. doi: 10.1016/j.jdent.2021.103633

Niu, J. Y., Yin, I. X., Wu, W. K. K., Li, Q.-L., Mei, M. L., & Chu, C. H. (2021). Antimicrobial peptides for the prevention and treatment of dental caries: A concise review. Archives of Oral Biology, 122, 105022. doi: 10.1016/j.archoralbio.2020.105022

Journal - Research Article

Won, J., Guan, G., Mei, L., Ma, T., Lai, Y., Zafar, S., Mei, M. L., & Thomson, W. M. (2021). A multicenter study of dental curricula in Asia/Pacific nations: The views and experiences of final-year dental students. Journal of Dental Education. Advance online publication. doi: 10.1002/jdd.12515

Dai, L. L., Mei, M. L., Chu, C. H., & Lo, E. C. M. (2021). Remineralizing effect of a new strontium-doped bioactive glass and fluoride on demineralized enamel and dentine. Journal of Dentistry, 103633. Advance online publication. doi: 10.1016/j.jdent.2021.103633

Dai, L. L., Nudelman, F., Chu, C. H., Lo, E. C. M., & Mei, M. L. (2021). The effects of strontium-doped bioactive glass and fluoride on hydroxyapatite crystallization. Journal of Dentistry. Advance online publication. doi: 10.1016/j.jdent.2021.103581

Zhang, J., Zhao, I. S., Yu, O. Y., Li, Q., Mei, M. L., Zhang, C., & Chung, C. H. (2021). Layer-by-layer self-assembly polyelectrolytes loaded with cyclic adenosine monophosphate enhances the osteo/odontogenic differentiation of stem cells from apical papilla. Journal of Biomedical Materials Research Part A, 109, 207-218. doi: 10.1002/jbm.a.37017

Yin, I. X., Zhao, I. S., Mei, M. L., Lo, E. C. M., Tang, J., Li, Q., … Chu, C. H. (2020). Synthesis and characterization of fluoridated silver nanoparticles and their potential as a non-staining anti-caries agent. International Journal of Nanomedicine, 15, 3207-3215. doi: 10.2147/ijn.S243202

Zhao, I. S., Yin, I. X., Mei, M. L., Lo, E. C. M., Tang, J., Li, Q., … Chu, C. H. (2020). Remineralising dentine caries using sodium fluoride with silver nanoparticles: An in vitro study. International Journal of Nanomedicine, 15, 2829-2839. doi: 10.2147/IJN.S247550

Yin, I. X., Yu, O. Y., Zhao, I. S., Mei, M. L., Li, Q. L., Tang, J., … Chu, C. H. (2020). Inhibition of dentine caries using fluoride solution with silver nanoparticles: An in vitro study. Journal of Dentistry, 103, 103512. doi: 10.1016/j.jdent.2020.103512

Jiang, M., Mei, M. L., Wong, M. C. M., Chu, C. H., & Lo, E. C. M. (2020). Influence of silver diamine fluoride treatment on the microtensile bond strength of glass ionomer cement to sound and carious dentin. Operative Dentistry, 45(5), E271-E279. doi: 10.2341/19-237-l

Dai, L. L., Mei, M. L., Chu, C. H., & Lo, E. C. M. (2020). Antibacterial effect of a new bioactive glass on cariogenic bacteria. Archives of Oral Biology, 117, 104833. doi: 10.1016/j.archoralbio.2020.104833

Wu, Q., Mei, M. L., Wu, X., Shi, S., Xu, Y., Chu, C. H., & Chen, Y. (2020). Remineralising effect of 45S5 bioactive glass on artificial caries in dentine. BMC Oral Health, 20, 49. doi: 10.1186/s12903-020-1038-4

Luk, K., Zao, I. S., Yu, O. Y., Mei, M. L., Gutknecht, N., & Chung, C. H. (2020). Caries prevention effects of silver diamine fluoride with 10,600 nm carbon dioxide laser irradiation on dentin. Photobiomodulation, Photomedicine, & Laser Surgery, 38(5), 295-300. doi: 10.1089/photob.2019.4720

Mei, M. L., Yan, Z., Duangthip, D., Niu, J. Y., Yu, O. Y., You, M., … Chu, C. H. (2020). Effect of silver diamine fluoride on plaque microbiome in children. Journal of Dentistry: X, 3, 100016. doi: 10.1016/j.jjodo.2020.100016

Yin, I. X., Yu, O. Y., Zhao, I. S., Mei, M. L., Li, Q.-L., Tang, J., & Chu, C.-H. (2019). Developing biocompatible silver nanoparticles using epigallocatechin gallate for dental use. Archives of Oral Biology, 102, 106-112. doi: 10.1016/j.archoralbio.2019.03.022

Zhao, I. S., Chu, S., Yu, O. Y., Mei, M. L., Chu, C. H., & Lo, E. C. M. (2019). Effect of silver diamine fluoride and potassium iodide on shear bond strength of glass ionomer cements to caries-affected dentine. International Dental Journal, 69, 341-347. doi: 10.1111/idj.12478

Yu, O. Y., Zhao, I. S., Mei, M. L., Lo, E. C.-M., & Chu, C.-H. (2018). Effect of silver nitrate and sodium fluoride with tri-calcium phosphate on Streptococcus mutans and demineralised dentine. International Journal of Molecular Sciences, 19(5), 1288. doi: 10.3390/ijms19051288

Yu, O. Y., Mei, M. L., Zhao, I. S., Li, Q.-L., Lo, E. C.-M., & Chu, C.-H. (2018). Remineralisation of enamel with silver diamine fluoride and sodium fluoride. Dental Materials, 34(12), e344-e352. doi: 10.1016/j.dental.2018.10.007

Yu, O. Y., Zhao, I. S., Mei, M. L., Lo, E. C. M., & Chu, C. H. (2018). Caries-arresting effects of silver diamine fluoride and sodium fluoride on dentine caries lesions. Journal of Dentistry, 78, 65-71. doi: 10.1016/j.jdent.2018.08.007

Mei, M. L., Nudelman, F., Marzec, B., Walker, J. M., Lo, E. C. M., Walls, A. W., & Chu, C. H. (2017). Formation of fluorohydroxyapatite with silver diamine fluoride. Journal of Dental Research, 96(10), 1122-1128. doi: 10.1177/0022034517709738

Fang, H., Li, Q.-L., Han, M., Mei, M. L., & Chu, C. H. (2017). Anti-proteolytic property and bonding durability of mussel adhesive protein-modified dentin adhesive interface. Dental Materials, 33(10), 1075-1083. doi: 10.1016/j.dental.2017.07.008

Zhao, I. S., Mei, M. L., Burrow, M. F., Lo, E. C.-M., & Chu, C.-H. (2017). Effect of silver diamine fluoride and potassium iodide treatment on secondary caries prevention and tooth discolouration in cervical glass ionomer cement restoration. International Journal of Molecular Sciences, 18(2), 340. doi: 10.3390/ijms18020340

Epasinghe, D. J., Kwan, S., Chu, D., Lei, M. M., Burrow, M. F., & Yiu, C. K. Y. (2017). Synergistic effects of proanthocyanidin, tri-calcium phosphate and fluoride on artificial root caries and dentine collagen. Materials Science & Engineering: C, 73, 293-299. doi: 10.1016/j.msec.2016.11.078

Yu, O. Y., Mei, M. L., Zhao, I. S., & Chu, C.-H. (2017). Effects of fluoride on two chemical models of enamel demineralization. Materials, 10(11), 1245. doi: 10.3390/ma10111245

Zhao, I. S., Mei, M. L., Li, Q.-L., Lo, E. C. M., & Chu, C.-H. (2017). Arresting simulated dentine caries with adjunctive application of silver nitrate solution and sodium fluoride varnish: An in vitro study. International Dental Journal, 67(4), 206-214. doi: 10.1111/idj.12291

Zhao, I. S., Mei, M. L., Zhou, Z. L., Burrow, M. F., Lo, E. C.-M., & Chu, C. H. (2017). Shear bond strength and remineralisation effect of a casein phosphopeptide-amorphous calcium phosphate-modified glass ionomer cement on artificial “caries-affected” dentine. International Journal of Molecular Sciences, 18(8), 1723. doi: 10.3390/ijms18081723

Zhao, I. S., Mei, M. L., Burrow, M. F., Lo, E. C.-M., & Chu, C.-H. (2017). Prevention of secondary caries using silver diamine fluoride treatment and casein phosphopeptide-amorphous calcium phosphate modified glass-ionomer cement. Journal of Dentistry, 57, 38-44. doi: 10.1016/j.jdent.2016.12.001

Mei, M. L., Lo, E. C.-M., & Chu, C.-H. (2016). Clinical use of silver diamine fluoride in dental treatment. Compendium of Continuing Education in Dentistry, 37(2), 93-98.

Mei, M. L., Chen, Y. M., Li, H., & Chu, C. H. (2016). Influence of the indirect restoration design on the fracture resistance: A finite element study. BioMedical Engineering OnLine, 15, 3. doi: 10.1186/s12938-015-0115-4

Mei, M. L., Li, Q.-L., & Chu, C. H. (2016). Inhibition of cariogenic plaque formation on root surface with polydopamine-induced-polyethylene glycol coating. Materials, 9(6), 414. doi: 10.3390/ma9060414

Gao, S. S., Zhang, S., Mei, M. L., Lo, E. C.-M., & Chu, C.-H. (2016). Caries remineralisation and arresting effect in children by professionally applied fluoride treatment: A systematic review. BMC Oral Health, 16, 12. doi: 10.1186/s12903-016-0171-6

Chen, J., Mei, M. L., Li, Q.-L., & Chu, C.-H. (2016). Mussel-inspired silver-nanoparticle coating on porous titanium surfaces to promote mineralization. RSC Advances, 6(106), 104025-104035. doi: 10.1039/c6ra20673e

Yin, J., Mei, M. L., Li, Q., Xia, R., Zhang, Z., & Chu, C. H. (2016). Self-cleaning and antibiofouling enamel surface by slippery liquid-infused technique. Scientific Reports, 6, 25924. doi: 10.1038/srep25924

Mei, M. L., Zhao, I. S., Ito, L., Lo, E. C.-M., & Chu, C.-H. (2016). Prevention of secondary caries by silver diamine fluoride. International Dental Journal, 66(2), 71-77. doi: 10.1111/idj.12207

Zhang, Y., Mao, W., Wang, J., Li, Q.-L., Mei, M. L., Chu, C. H., … Zhang, Z.-H. (2015). Antibacterial membrane with a bone-like structure for guided bone regeneration. Journal of Nanomaterials, 2015, 784574. doi: 10.1155/2015/784574

Wu, X.-T., Mei, M. L., Li, Q.-L., Cao, C. Y., Chen, J.-L., Xia, R., … Chu, C. H. (2015). A direct electric field-aided biomimetic mineralization system for inducing the remineralization of dentin collagen matrix. Materials, 8(11), 7889-7899. doi: 10.3390/ma8115433

Mei, M. L., Ito, L., Zhang, C. F., Lo, E. C. M., & Chu, C. H. (2015). Effect of laser irradiation on the fluoride uptake of silver diamine fluoride treated dentine. Lasers in Medical Science, 30(3), 985-991. doi: 10.1007/s10103-014-1521-8

Mei, M. L., So, S. Y. C., Li, H., & Chu, C.-H. (2015). Effect of heat treatment on the physical properties of provisional crowns during polymerization: An in vitro study. Materials, 8(4), 1766-1777. doi: 10.3390/ma8041766

Chu, C.-H., Mei, M. L., & Nalliah, R. P. (2015). A survey of practices of tunnel preparation among dentists who attended the 100th FDI Annual World Dental Congress. Journal of Investigative & Clinical Dentistry, 6(1), 63-68. doi: 10.1111/jicd.12081

Mei, M. L., Ito, L., Cao, Y., Lo, E. C. M., Li, Q. L., & Chu, C. H. (2014). An ex vivo study of arrested primary teeth caries with silver diamine fluoride therapy. Journal of Dentistry, 42(4), 395-402. doi: 10.1016/j.jdent.2013.12.007

Li, Q.-L., Ning, T.-Y., Cao, Y., Zhang, W.-b., Mei, M. L., & Chu, C. H. (2014). A novel self-assembled oligopeptide amphiphile for biomimetic mineralization of enamel. BMC Biotechnology, 14, 32. doi: 10.1186/1472-6750-14-32

Cao, Y., Liu, W., Ning, T., Mei, M. L., Li, Q.-L., Lo, E. C. M., & Chu, C. H. (2014). A novel oligopeptide simulating dentine matrix protein 1 for biomimetic mineralization of dentine. Clinical Oral Investigations, 18(3), 873-881. doi: 10.1007/s00784-013-1035-y

Wu, X.-T., Cao, Y., Mei, M. L., Chen, J.-L., Li, Q.-L., & Chu, C. H. (2014). An electrophoresis-aided biomineralization system for regenerating dentin- and enamel-like microstructures for the self-healing of tooth defects. Crystal Growth & Design, 14(11), 5537-5548. doi: 10.1021/cg5007633

Cao, Y., Mei, M. L., Li, Q.-L., Lo, E. C. M., & Chu, C. H. (2014). Agarose hydrogel biomimetic mineralization model for the regeneration of enamel prismlike tissue. ACS Applied Materials & Interfaces, 6(1), 410-420. doi: 10.1021/am4044823

Mei, M. L., Ito, L., Cao, Y., Li, Q. L., Chu, C. H., & Lo, E. C. M. (2014). The inhibitory effects of silver diamine fluorides on cysteine cathepsins. Journal of Dentistry, 42(3), 329-335. doi: 10.1016/j.jdent.2013.11.018

Cao, Y., Mei, M. L., Li, Q.-L., Lo, E. C. M., & Chu, C. H. (2014). Enamel prism-like tissue regeneration using enamel matrix derivative. Journal of Dentistry, 42(12), 1535-1542. doi: 10.1016/j.jdent.2014.08.014

Mei, M. L., Ito, L., Chu, C. H., Lo, E. C. M., & Zhang, C. F. (2014). Prevention of dentine caries using silver diamine fluoride application followed by Er:YAG laser irradiation: An in vitro study. Lasers in Medical Science, 29(6), 1785-1791. doi: 10.1007/s10103-013-1329-y

Mei, M. L., Ito, L., Cao, Y., Li, Q. L., Lo, E. C. M., & Chu, C. H. (2013). Inhibitory effect of silver diamine fluoride on dentine demineralisation and collagen degradation. Journal of Dentistry, 41(9), 809-817. doi: 10.1016/j.jdent.2013.06.009

Cao, Y., Mei, M. L., Xu, J., Lo, E. C. M., Li, Q., & Chu, C. H. (2013). Biomimetic mineralisation of phosphorylated dentine by CPP-ACP. Journal of Dentistry, 41(9), 818-825. doi: 10.1016/j.jdent.2013.06.008

Mei, M. L., Chu, C. H., Low, K. H., Che, C. M., & Lo, E. C. M. (2013). Caries arresting effect of silver diamine fluoride on dentine carious lesion with S. mutans and L. acidophilus dual-species cariogenic biofilm. Medicina Oral, Patología Oral y Cirugía Bucal, 18(6), e824-e831. doi: 10.4317/medoral.18831

Mei, M. L., Chu, C. H., Lo, E. C. M., & Samaranayake, L. P. (2013). Preventing root caries development under oral biofilm challenge in an artificial mouth. Medicina Oral, Patología Oral y Cirugía Bucal, 18(4), e557-e563. doi: 10.4317/medoral.18768

Mei, M. L., Li, Q.-L., Chu, C.-H., Lo, E. C.-M., & Samaranayake, L. P. (2013). Antibacterial effects of silver diamine fluoride on multi-species cariogenic biofilm on caries. Annals of Clinical Microbiology & Antimicrobials, 12, 4. doi: 10.1186/1476-0711-12-4

Mei, M. L., Chu, C. H., Lo, E. C. M., & Samaranayake, L. P. (2013). Fluoride and silver concentrations of silver diammine fluoride solutions for dental use. International Journal of Paediatric Dentistry, 23(4), 279-285. doi: 10.1111/ipd.12005

Mei, M. L., Li, Q. L., Chu, C. H., Yiu, C. K. Y., & Lo, E. C. M. (2012). The inhibitory effects of silver diamine fluoride at different concentrations on matrix metalloproteinases. Dental Materials, 28(8), 903-908. doi: 10.1016/j.dental.2012.04.011

Chu, C. H., Mei, L., Seneviratne, C. J., & Lo, E. C. M. (2012). Effects of silver diamine fluoride on dentine carious lesions induced by Streptococcus mutans and Actinomyces naeslundii biofilms. International Journal of Paediatric Dentistry, 22(1), 2-10. doi: 10.1111/j.1365-263X.2011.01149.x

Chu, C. H., Mei, M. L., & Lo, E. C. (2010). Use of fluorides in dental caries management. General Dentistry, 58(1), 37-43.

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Journal - Research Other

Niu, J. Y., Yin, I. X., Wu, W. K. K., Li, Q.-L., Mei, M. L., & Chu, C. H. (2021). Antimicrobial peptides for the prevention and treatment of dental caries: A concise review. Archives of Oral Biology, 122, 105022. doi: 10.1016/j.archoralbio.2020.105022

Niu, J. Y., Yin, I. X., Mei, M. L., Wu, W. K. K., Li, Q.-L., & Chu, C. H. (2021). The multifaceted roles of antimicrobial peptides in oral diseases. Molecular Oral Microbiology. Advance online publication. doi: 10.1111/omi.12333

Jiang, M., Mei, M. L., Wong, M. C. M., Chu, C. H., & Lo, E. C. M. (2020). Effect of silver diamine fluoride solution application on the bond strength of dentine to adhesives and to glass ionomer cements: A systematic review. BMC Oral Health, 20, 40. doi: 10.1186/s12903-020-1030-z

Yu, O. Y., Zaeneldin, A. M., Hamama, H. H. H., Mei, M. L., Patel, N., & Chu, C.-H. (2020). Conservative composite resin restoration for proximal caries: Two case reports. Clinical, Cosmetic & Investigational Dentistry, 12, 415-422. doi: 10.2147/CCIDE.S270453

Yin, I. X., Zhao, I. S., Mei, M. L., Li, Q., Yu, O. Y., & Chu, C. H. (2020). Use of silver nanomaterials for caries prevention: A concise review. International Journal of Nanoscience, 15, 3181-3191. doi: 10.2147/ijn.S253833

Chawhuaveang, D. D., Yu, O. Y., Yin, I. X., Lam, W. Y.-H., Mei, M. L., & Chu, C.-H. (2020). Acquired salivary pellicle and oral diseases: A literature review. Journal of Dental Sciences. Advance online publication. doi: 10.1016/j.jds.2020.10.007

Zhang, Y., Qi, Y., Lo, E. C. M., McGrath, C., Mei, M. L., & Dai, R. (2020). Using NGS to detect oral microbiome change following periodontal interventions: A systematic review. Oral Diseases. Advance online publication. doi: 10.1111/odi.13405

Yin, I. X., Zhang, J., Zhao, I. S., Mei, M. L., Li, Q., & Chu, C. H. (2020). The antibacterial mechanism of silver nanoparticles and its application in dentistry. International Journal of Nanomedicine, 15, 2555-2562. doi: 10.2147/IJN.S246764

Dai, L. L., Mei, M. L., Chu, C. H., & Lo, E. C. M. (2019). Mechanisms of bioactive glass on caries management: A review. Materials, 12(24), 4183. doi: 10.3390/ma12244183

Luk, K., Yu, O. Y., Mei, M. L., Gutknecht, N., Chu, C. H., & Zhao, I. S. (2019). Effects of carbon dioxide lasers on preventing caries: A literature review. Lasers in Dental Science, 3(2), 83-90. doi: 10.1007/s41547-019-00065-8

Mei, M. L., Lo, E. C. M., & Chu, C. H. (2018). Arresting dentine caries with silver diamine fluoride: What’s behind it? Journal of Dental Research, 97(7), 751-758. doi: 10.1177/0022034518774783

Zhao, I. S., Gao, S. S., Hiraishi, N., Burrow, M. F., Duangthip, D., Mei, M. L., … Chu, C.-H. (2018). Mechanisms of silver diamine fluoride on arresting caries: A literature review. International Dental Journal, 68(2), 67-76. doi: 10.1111/idj.12320

Yu, O. Y., Zhao, I. S., Mei, M. L., Lo, E. C.-M., & Chu, C.-H. (2017). A review of the common models used in mechanistic studies on demineralization-remineralization for cariology research. Dentistry, 5(2), 20. doi: 10.3390/dj5020020

Yu, O. Y., Zhao, I. S., Mei, M. L., Lo, E. C.-M., & Chu, C.-H. (2017). Dental biofilm and laboratory microbial culture models for cariology research. Dentistry, 5(2), 21. doi: 10.3390/dj5020021

Gao, S. S., Zhao, I. S., Hiraishi, N., Duangthip, D., Mei, M. L., Lo, E. C. M., & Chu, C. H. (2016). Clinical trials of silver diamine fluoride in arresting caries among children: A systematic review. JDR Clinical & Translational Research, 1(3), 201-210. doi: 10.1177/2380084416661474

Cao, C. Y., Mei, M. L., Li, Q.-L., Lo, E. C. M., & Chu, C. H. (2015). Methods for biomimetic remineralization of human dentine: A systematic review. International Journal of Molecular Sciences, 16(3), 4615-4627. doi: 10.3390/ijms16034615

Cao, C. Y., Mei, M. L., Li, Q.-l., Lo, E. C. M., & Chu, C. H. (2015). Methods for biomimetic mineralisation of human enamel: A systematic review. Materials, 8(6), 2873-2886. doi: 10.3390/ma8062873

Chu, C.-H., Lee, A. H.-C., Zheng, L., Mei, M. L., & Chan, G. C.-F. (2014). Arresting rampant dental caries with silver diamine fluoride in a young teenager suffering from chronic oral graft versus host disease post-bone marrow transplantation: A case report. BMC Research Notes, 7, 3. doi: 10.1186/1756-0500-7-3

Chu, C.-H., Mei, M. L., Cheung, C., & Nalliah, R. P. (2013). Restoring proximal caries lesions conservatively with tunnel restorations. Clinical, Cosmetic & Investigational Dentistry, 5, 43-50. doi: 10.2147/CCIDE.S48567

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