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Health Sciences staff profiles

Mozammel Haque Bhuiyan

PositionPhD Student
DepartmentDepartment of Anatomy
QualificationsMSc BSc(Hons)
Research summaryRegeneration of neural tissue using biopolymer hydrogels
TeachingDemonstrating in Anatomy undergraduate papers
Memberships
  • Australasian Society for Biomaterials and Tissue Engineering (ASBTE)
  • Society for Biomaterials (SFB)

Research

Ischemic stroke is one of the leading causes of adult disability worldwide. The primary reason for the lasting functional impairment following stroke is the brain’s limited ability to regenerate after an injury.Treatment measures, such as systemic delivery of drugs and growth factors are limited by the blood-brain barrier and off-target effects. Recently, localised delivery by biopolymer hydrogels has gained significant attention to overcome this problem.

The aim of my PhD project is to design and optimise a biopolymer hydrogel to be used as a scaffold to regenerate brain tissue following stroke.

Publications

Griem-Krey, N., Klein, A. B., Clausen, B. H., Namini, M. R. J., Nielsen, P. V., Bhuiyan, M., … Clarkson, A. N., & Wellendorph, P. (2023). The GHB analogue HOCPCA improves deficits in cognition and sensorimotor function after MCAO via CaMKIIα. Journal of Cerebral Blood Flow & Metabolism. Advance online publication. doi: 10.1177/0271678x231167920

Bhuiyan, M. H., Houlton, J., & Clarkson, A. N. (2023). Hydrogels and nanoscaffolds for long-term intraparenchymal therapeutic delivery after stroke. In V. T. Karamyan & A. M. Stowe (Eds.), Neural repair: Methods and protocols: Methods in molecular biology (Vol. 2616). (pp. 379-390). New York, NY: Springer Nature. doi: 10.1007/978-1-0716-2926-0_26

Bhuiyan, M. H., Clarkson, A. N., & Ali, M. A. (2023). Optimization of thermoresponsive chitosan/β-glycerophosphate hydrogels for injectable neural tissue engineering application. Colloids & Surfaces B. Advance online publication. doi: 10.1016/j.colsurfb.2023.113193

Rayhan, M. A., Hossen, M. S., Niloy, M. S., Bhuiyan, M. H., Paul, S., & Shakil, M. S. (2021). Biopolymer and biomaterial conjugated iron oxide nanomaterials as prostate cancer theranostic agents: A comprehensive review. Symmetry, 13, 974. doi: 10.3390/sym13060974

Ali, M. A., & Bhuiyan, M. H. (2021). Types of biomaterials useful in brain repair. Neurochemistry International, 146, 105034. doi: 10.1016/j.neuint.2021.105034