Gemma Laws, MSc, PhD Candidate
Supervisors: Professor Michael Schultz, Associate Professor Roslyn Kemp
Immune cell activation and function in inflammatory bowel disease
Crohn’s disease (CD) is a chronic inflammatory bowel disease. Approximately 15,000 people in New Zealand are currently diagnosed with CD. Crohn's Disease is a heterogeneous disease that involves a number of contributing factors: the immune response, genetic susceptibility, environmental factors, the intestinal epithelial barrier, and the host microbiome. Individuals with CD have a more highly activated immune response than healthy individuals that results in gut inflammation.
One way to study CD and account for the multiple contributing factors is via intestinal organoids. Organoids provide an invaluable research tool as they are grown from stem cells of individual patients. This study aims to use human intestinal organoids to model the gut immune responses in inflammatory bowel disease. Gemma’s presentation will introduce her work in further detail. All University of Otago and Southern District Health Board staff and students are welcome to attend.
Zoom ID: 785276986
|Date||Friday, 28 May 2021|
|Time||12:30pm - 1:30pm|
|Event Category||Health Sciences|
|Location||9th floor seminar room, Dunedin Public Hospital, Dunedin, and via Zoom|
|Contact Name||Amanda Buchanan|