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DSM staff profile

Dr Christopher Jackson

PositionConsultant Medical Oncologist
DepartmentDepartment of Medicine (Dunedin)
QualificationsMB ChB FRACP
Research summaryGastrointestinal cancers, particularly colorectal cancer; clinical trials in cancer.
ClinicalGastrointestinal cancer, lymphoma, melanoma, genitourinary cancer.

Research

Clinical aspects of Colorectal Cancer and its management, as well as health services research. Collaborating with lab-based scientists on genetic aspects of cancer, treatment and toxicity, as well as immunotherapy in a variety of solid tumours.

Publications

Jackson, C. G. C. A., Hung, T., Segelov, E., Barlow, P., Prenen, H., McLaren, B., Hung, N. A., Clarke, K., … Deva, S. (2021). Oral paclitaxel with encequidar compared to intravenous paclitaxel in patients with advanced cancer: A randomised crossover pharmacokinetic study. British Journal of Clinical Pharmacology. Advance online publication. doi: 10.1111/bcp.14886

Millar, E., Gurney, J., Beuker, S., Goza, M., Hamilton, M.-A., Hardie, C., Jackson, C. G. C. A., … Sarfati, D. (2021). Maintaining cancer services during the COVID-19 pandemic: The Aotearoa New Zealand experience. Lancet Regional Health: Western Pacific, 11, 100172. doi: 10.1016/j.lanwpc.2021.100172

Gurney, J. K., Millar, E., Dunn, A., Pirie, R., Mako, M., Manderson, J., … Jackson, C. G. C. A., … Sarfati, D. (2021). The impact of the COVID-19 pandemic on cancer diagnosis and service access in New Zealand: A country pursuing COVID-19 elimination. Lancet Regional Health: Western Pacific, 10, 100127. doi: 10.1016/j.lanwpc.2021.100127

Morgan, E., Soerjomataram, I., Gavin, A. T., Rutherford, M. J., Gatenby, P., Bardot, A., … Jackson, C., … Arnold, M. (2021). International trends in oesophageal cancer survival by histological subtype between 1995 and 2014. Gut, 70, 234-242. doi: 10.1136/gutjnl-2020-321089

Blackmore, T., Norman, K., Kidd, J., Cassim, S., Chepulis, L., Keenan, R., … Jackson, C., Stokes, T., … Lawrenson, R. (2020). Barriers and facilitators to colorectal cancer diagnosis in New Zealand: A qualitative study. BMC Family Practice, 21, 206. doi: 10.1186/s12875-020-01276-w

Gurney, J. K., Millar, E., Dunn, A., Pirie, R., Mako, M., Manderson, J., … Jackson, C. G. C. A., … Sarfati, D. (2021). The impact of the COVID-19 pandemic on cancer diagnosis and service access in New Zealand: A country pursuing COVID-19 elimination. Lancet Regional Health: Western Pacific, 10, 100127. doi: 10.1016/j.lanwpc.2021.100127

Journal - Research Article

Jackson, C. G. C. A., Hung, T., Segelov, E., Barlow, P., Prenen, H., McLaren, B., Hung, N. A., Clarke, K., … Deva, S. (2021). Oral paclitaxel with encequidar compared to intravenous paclitaxel in patients with advanced cancer: A randomised crossover pharmacokinetic study. British Journal of Clinical Pharmacology. Advance online publication. doi: 10.1111/bcp.14886

Journal - Research Article

Millar, E., Gurney, J., Beuker, S., Goza, M., Hamilton, M.-A., Hardie, C., Jackson, C. G. C. A., … Sarfati, D. (2021). Maintaining cancer services during the COVID-19 pandemic: The Aotearoa New Zealand experience. Lancet Regional Health: Western Pacific, 11, 100172. doi: 10.1016/j.lanwpc.2021.100172

Journal - Research Article

Morgan, E., Soerjomataram, I., Gavin, A. T., Rutherford, M. J., Gatenby, P., Bardot, A., … Jackson, C., … Arnold, M. (2021). International trends in oesophageal cancer survival by histological subtype between 1995 and 2014. Gut, 70, 234-242. doi: 10.1136/gutjnl-2020-321089

Journal - Research Article

Blackmore, T., Norman, K., Kidd, J., Cassim, S., Chepulis, L., Keenan, R., … Jackson, C., Stokes, T., … Lawrenson, R. (2020). Barriers and facilitators to colorectal cancer diagnosis in New Zealand: A qualitative study. BMC Family Practice, 21, 206. doi: 10.1186/s12875-020-01276-w

Journal - Research Article

Gurney, J., Stanley, J., Jackson, C., & Sarfati, D. (2020). Stage at diagnosis for Māori cancer patients: Disparities, similarities and data limitations. New Zealand Medical Journal, 133(1508), 43-64. Retrieved from https://www.nzma.org.nz/journal

Journal - Research Article

Gurney, J., Stanley, J., McLeod, M., Koea, J., Jackson, C., & Sarfati, D. (2020). Disparities in cancer-specific survival between Māori and non-Māori New Zealanders, 2007-2016. JCO Global Oncology, 6, 766-774. doi: 10.1200/go.20.00028

Journal - Research Article

Jackson, C. G. C. A., Bissett, I., Macfarlane, S., & Costello, S. (2020). Improving cancer services and survival in New Zealand. Journal of Cancer Policy, 23, 100216. doi: 10.1016/j.jcpo.2020.100216

Journal - Research Article

Segelov, E., Underhill, C., Prenen, H., Karapetis, C., Jackson, C., Nott, L., … MacIntyre, C. R. (2020). Practical considerations for treating patients with cancer in the COVID-19 pandemic. JCO Oncology Practice, 16(8), 467-482. doi: 10.1200/op.20.00229

Journal - Research Article

Walker, S., Egan, R., Young, J., Jaye, C., & Jackson, C. (2020). A citizens' jury on euthanasia/assisted dying: Does informed deliberation change people's views? Health Expectations, 23, 388-395. doi: 10.1111/hex.13008

Journal - Research Article

Zou, D., Day, R., Cocadiz, J. A., Parackal, S., Mitchell, W., Black, M. A., … Jackson, C., & Guilford, P. (2020). Circulating tumor DNA is a sensitive marker for routine monitoring of treatment response in advanced colorectal cancer. Carcinogenesis, 41(11), 1507-1517. doi: 10.1093/carcin/bgaa102

Journal - Research Article

So, Y. J., Jameson, M., Newton, V., O'Donnell, A., Jeffery, M., Jackson, C., … Wilson, M. K. (2019). Investigating strategies to improve clinical trial opportunities for patients with cancer in New Zealand: INSIGHT. New Zealand Medical Journal, 132(1498), 10-31. Retrieved from https://www.nzma.org.nz/journal

Journal - Research Article

Young, J., Egan, R., Walker, S., Graham-DeMello, A., & Jackson, C. (2019). The euthanasia debate: Synthesising the evidence on New Zealander's attitudes. Kōtuitui, 14(1), 1-21. doi: 10.1080/1177083X.2018.1532915

Journal - Research Article

Gibbs, P., Heinemann, V., Sharma, N. K., Taieb, J., Ricke, J., Peeters, M., … Robinson, B., Jackson, C., … for the SIRFLOX and FOXFIRE Global Trial Investigators, including Perez, D. (2018). Effect of primary tumor side on survival outcomes in untreated patients with metastatic colorectal cancer when selective internal radiation therapy is added to chemotherapy: Combined analysis of two randomized controlled studies. Clinical Colorectal Cancer, 17(4), e617-e629. doi: 10.1016/j.clcc.2018.06.001

Journal - Research Article

Hill, A. G., Findlay, M. P., Burge, M. E., Jackson, C., Alfonso, P. G., Samuel, L., … Tabernero, J. (2018). Phase II study of the dual EGFR/HER3 inhibitor duligotuzumab (MEHD7945A) versus cetuximab in combination with FOLFIRI in second-line RAS wild-type metastatic colorectal cancer. Clinical Cancer Research, 24(10), 2276-2284. doi: 10.1158/1078-0432.Ccr-17-0646

Journal - Research Article

Lawrence, B., Blenkiron, C., Parker, K., Tsai, P., Fitzgerald, S., Shields, P., … Black, M., … Robinson, B., … Carroll, R., … Morrin, H., … Jackson, C., … Print, C. (2018). Recurrent loss of heterozygosity correlates with clinical outcome in pancreatic neuroendocrine cancer. npj Genomic Medicine, 3, 18. doi: 10.1038/s41525-018-0058-3

Journal - Research Article

Sharples, K., Firth, M., Hinder, V., Hill, A., Jeffery, M., Sarfati, D., … Atmore, C., … Derrett, S., … Keating, J., … Jackson, C., & Findlay, M. (2018). The New Zealand PIPER Project: Colorectal cancer survival according to rurality, ethnicity and socioeconomic deprivation: Results from a retrospective cohort study. New Zealand Medical Journal, 1476(131), 24-39. Retrieved from https://www.nzma.org.nz/journal

Journal - Research Article

Grant, M. L., Shields, N., Neumann, S., Kramer, K., Bonato, A., Jackson, C., Baird, M. A., & Young, S. L. (2017). Combining dendritic cells and B cells for presentation of oxidised tumour antigens to CD8+ T cells. Clinical & Translational Immunology, 6(7), e149. doi: 10.1038/cti.2017.28

Journal - Research Article

Li, K., Donaldson, B., Young, V., Ward, V., Jackson, C., Baird, M., & Young, S. (2017). Adoptive cell therapy with CD4+ T helper 1 cells and CD8+ cytotoxic T cells enhances complete rejection of an established tumour, leading to generation of endogenous memory responses to non-targeted tumour epitopes. Clinical & Translational Immunology, 6(10), e160. doi: 10.1038/cti.2017.37

Journal - Research Article

Segelov, E., Chan, D., Lawrence, B., Pavlakis, N., Kennecke, H. F., Jackson, C., … Singh, S. (2017). Identifying and prioritizing gaps in neuroendocrine tumor research: A modified Delphi process with patients and health care providers to set the research action plan for the newly formed Commonwealth Neuroendocrine Tumor Collaboration. Journal of Global Oncology, 3(4), 380-388. doi: 10.1200/jgo.2016.006916

Journal - Research Article

Tiong, J., Gray, A., Jackson, C., Thompson-Fawcett, M., & Schultz, M. (2017). Audit of the association between length of time spent on diagnostic work-up and tumour stage in patients with symptomatic colon cancer. ANZ Journal of Surgery, 87(3), 138-142. doi: 10.1111/ans.12804

Journal - Research Article

Firth, M. J., Sharples, K. J., Hinder, V. A., Macapagal, J., Sarfati, D., Derrett, S. L., … Atmore, C., Keating, J. P., Jeffery, M., … Jackson, C. G. C. A., & Findlay, M. P. N. (2016). Methods of a national colorectal cancer cohort study: The PIPER Project. New Zealand Medical Journal, 129(1440), 25-36. Retrieved from https://www.nzma.org.nz/journal

Journal - Research Article

Li, K., Baird, M., Yang, J., Jackson, C., Ronchese, F., & Young, S. (2016). Conditions for the generation of cytotoxic CD4+ Th cells that enhance CD8+ CTL-mediated tumor regression. Clinical & Translational Immunology, 5(8), e95. doi: 10.1038/cti.2016.46

Journal - Research Article

Sarfati, D., Koczwara, B., & Jackson, C. (2016). The impact of comorbidity on cancer and its treatment. CA: A Cancer Journal for Clinicians, 66(4), 337-350. doi: 10.3322/caac.21342

Journal - Research Article

Stairmand, J., Signal, L., Sarfati, D., Jackson, C., Batten, L., Holdaway, M., & Cunningham, C. (2015). Consideration of comorbidity in treatment decision making in multidisciplinary cancer team meetings: A systematic review. Annals of Oncology, 26, 1325-1332. doi: 10.1093/annonc/mdv025

Journal - Research Article

Jackson, C. G. C. A., Sharples, K., Thompson, P. I., O'Donnell, A., Robinson, B. A., Perez, D. J., … Findlay, M. P. (2014). Dose-intense capecitabine, oxaliplatin and bevacizumab as first line treatment for metastatic, unresectable colorectal cancer: A multi-centre phase II study. BMC Cancer, 14, 737. doi: 10.1186/1471-2407-14-737

Journal - Research Article

Bidwell, S., Simpson, A., Sullivan, R., Robinson, B., Thomas, W., Jackson, C., … Clarke, T. (2013). A workforce survey of New Zealand medical oncologists. New Zealand Medical Journal, 126(1371). Retrieved from http://www.nzma.org.nz/journal

Journal - Research Article

Moorcraft, S. Y., Chau, I., Peckitt, C., Cunningham, D., Rao, S., Yim, K. L., … Jackson, C. G. C. A., … Swanton, C. (2013). Patupilone in patients with pretreated metastatic/locally recurrent colorectal cancer: Results of the Phase II CINATRA trial. Investigational New Drugs, 31(5), 1339-1344. doi: 10.1007/s10637-013-9990-3

Journal - Research Article

Pullar, J. M., Chisholm, A., & Jackson, C. (2012). Dietary information for colorectal cancer survivors: An unmet need. New Zealand Medical Journal, 125(1356). Retrieved from http://www.nzma.org.nz/journal

Journal - Research Article

Richter, K. K., Dempster, A., Tos, A. P. D., Premkumar, R., & Jackson, C. (2011). Challenging differential diagnosis of a wild-type gastrointestinal stromal tumour (GIST) or rare reticular perineurioma of the stomach? The role for mutational analysis. New Zealand Medical Journal, 124(1331). Retrieved from http://journal.nzma.org.nz/journal/124-1331/4583/content.pdf

Journal - Research Article

Jackson, C., Sirohi, B., Cunningham, D., Horwich, A., Thomas, K., & Wotherspoon, A. (2010). Lymphocyte-predominant Hodgkin lymphoma: Clinical features and treatment outcomes from a 30-year experience. Annals of Oncology, 21(10), 2061-2068. doi: 10.1093/annonc/mdq063

Journal - Research Article

Jackson, C., Cunningham, D., Oliveira, J., on behalf of the ESMO Guidelines Working Group. (2009). Gastric cancer: ESMO clinical recommendations for diagnosis, treatment and follow-up. Annals of Oncology, 20(Suppl. 4), iv34-iv36. doi: 10.1093/annonc/mdp119

Journal - Research Article

Jackson, C., & Cunningham, D. (2008). Where to position monoclonal antibodies in first-line treatment of advanced colorectal cancer. European Journal of Cancer, 44, 652-662. doi: 10.1016/j.ejca.2008.01.021

Journal - Research Article

Kong, G., Jackson, C., Koh, D. M., Lewington, V., Sharma, B., Brown, G., … Cook, G. J. R. (2008). The use of 18F-FDG PET/CT in colorectal liver metastases—comparison with CT and liver MRI. European Journal of Nuclear Medicine & Molecular Imaging, 35(7), 1323-1329. doi: 10.1007/s00259-008-0743-z

Journal - Research Article

Jackson, C., Mochlinski, K., & Cunningham, D. (2007). Therapeutic options in gastric cancer: Neoadjuvant chemotherapy vs postoperative chemoradiotherapy. Oncology, 21(9), 1084-1087.

Journal - Research Article

Jackson, C., Starling, N., Chua, Y. J., & Cunningham, D. (2007). Pharmacotherapy for oesophagogastric cancer. Drugs, 67(17), 2539-2556.

Journal - Research Article

Hung, N. A., Jackson, C., Nicholson, M., & Highton, J. (2006). Pregnancy-related polymyositis and massive perivillous fibrin deposition in the placenta: Are they pathogenetically related? Arthritis & Rheumatism, 55(1), 154-156. doi: 10.1002/art.21710

Journal - Research Article

Sarfati, D., & Jackson, C. (2020). Context of cancer control in New Zealand. Journal of Cancer Policy, 23, 100211. doi: 10.1016/j.jcpo.2019.100211

Journal - Research Other

Sarfati, D., & Jackson, C. G. C. A. (2020). Preface to the NZ series on Cancer Control. Journal of Cancer Policy, 23, 100223. doi: 10.1016/j.jcpo.2020.100223

Journal - Research Other

Weinkove, R., McQuilten, Z. K., Adler, J., Agar, M. R., Blyth, E., Cheng, A. C., … Jackson, C., … Teh, B. W. (2020). Managing haematology and oncology patients during the COVID-19 pandemic: Interim consensus guidance. Medical Journal of Australia, 212(10), 481-489. doi: 10.5694/mja2.50607

Journal - Research Other

Gurney, J., Campbell, S., Jackson, C., & Sarfati, D. (2019). Equity by 2030: Achieving equity in survival for Māori cancer patients. New Zealand Medical Journal, 132(1506), 66-76. Retrieved from https://www.nzma.org.nz/journal

Journal - Research Other

Jackson, C. G. C. A., Morris, T., Hung, N., & Hung, T. (2019). Breast milk paclitaxel excretion following intravenous chemotherapy: A case report. British Journal of Cancer, 121, 421-424. doi: 10.1038/s41416-019-0529-z

Journal - Research Other

Sarfati, D., Jackson, C. G. C. A., Macfarlane, S., Bissett, I., Robson, B., Gurney, J., Kemp, R., … McMenamin, J. (2019). Cancer Care at a Crossroads: Time to make a choice. New Zealand Medical Journal, 132(1493), 6-11. Retrieved from https://www.nzma.org.nz/journal

Journal - Research Other

Sarfati, D., & Jackson, C. (2018). Cancer inequalities endure despite NHS reforms. BMJ, 360, k989. doi: 10.1136/bmj.k989

Journal - Research Other

Lim, Y. K., Jackson, C., Dauway, E. L., & Richter, K. K. (2017). Risk factors for adverse outcome for elderly patients undergoing curative oncological resection for gastrointestinal malignancies. Visceral Medicine, 33(4), 254-261. doi: 10.1159/000475938

Journal - Research Other

Jackson, C. G. C. A. (2016). Follow-up of cancer in New Zealand: Time to review the model of care. New Zealand Medical Journal, 129(1440), 18-21. Retrieved from https://www.nzma.org.nz/journal

Journal - Research Other

Jackson, C. G. C. A., & Sarfati, D. (2016). How 'modifiable' are 'modifiable risk factors' for cancer? New Zealand Medical Journal, 129(1447), 7-9. Retrieved from http://www.nzma.org.nz/journal

Journal - Research Other

Jackson, C., Ehrenberg, N., Frizelle, F., Sarfati, D., Balasingham, A., Pearse, M., … Bissett, I. (2014). Rectal cancer: Future directions and priorities for treatment, research and policy in New Zealand. New Zealand Medical Journal, 127(1395). Retrieved from http://www.nzma.org.nz/journal

Journal - Research Other

Jackson, C., Robinson, B., & Findlay, M. (2014). Cancer services to 2025 in New Zealand: Investing in research-driven quality care. New Zealand Medical Journal, 127(1395). Retrieved from http://www.nzma.org.nz/journal

Journal - Research Other

Jackson, C., McCall, J., Robinson, B., Sharples, K., & Findlay, M. (2013). Cancer trials in New Zealand: Patients are not the problem. New Zealand Medical Journal, 126(1381). Retrieved from http://www.nzma.org.nz/journal

Journal - Research Other

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