Accessibility Skip to Global Navigation Skip to Local Navigation Skip to Content Skip to Search Skip to Site Map Menu

DSM staff profile

Associate Professor Chris Baldi

PositionResearch Associate Professor
DepartmentDepartment of Medicine (Dunedin)
QualificationsMSc PhD FACSM
Research summaryDiabetes and cardiovascular dysfunction

Research

My general area of research is to examine the causes and prevention of cardiovascular dysfunction in patients with diabetes (type 1 and 2). Interests include:

  • Exercise intolerance in diabetes
  • Myocardial and pulmonary dysfunction in diabetes
  • Paediatric diabetes research

Publications

Ng, Y. H., Lamberts, R. R., Jones, P. P., Sammut, I. A., Diffee, G. M., Wilkins, G. T., & Baldi, J. C. (2022). Sarco/endoplasmic reticulum calcium ATPase activity is unchanged despite increased myofilament calcium sensitivity in Zucker type 2 diabetic fatty rat heart. Scientific Reports, 12(1), 16904. doi: 10.1038/s41598-022-20520-0

Greenman, A. C., Diffee, G. M., Power, A. S., Wilkins, G. T., Gold, O. M. S., Erickson, J. R., & Baldi, J. C. (2022). Treadmill running increases the calcium sensitivity of myofilaments in diabetic rats. Journal of Applied Physiology. Advance online publication. doi: 10.1152/japplphysiol.00785.2021

Woodfield, J. C., Clifford, K., Wilson, G. A., Munro, F., & Baldi, J. C. (2022). Short-term high-intensity interval training improves fitness before surgery: A randomised clinical trial. Scandinavian Journal of Medicine & Science in Sports, 32, 856-865. doi: 10.1111/sms.14130

Chiavaroli, V., Hopkins, S. A., Biggs, J. B., Rodrigues, R. O., Seneviratne, S. N., Baldi, J. C., … Derraik, J. G. B. (2021). The associations between maternal BMI and gestational weight gain and health outcomes in offspring at age 1 and 7 years. Scientific Reports, 11, 20865. doi: 10.1038/s41598-021-99869-7

Greenman, A. C., Diffee, G. M., Power, A. S., Wilkins, G. T., Gold, O. M. S., Erickson, J. R., & Baldi, J. C. (2021). Increased myofilament calcium sensitivity is associated with decreased cardiac troponin I phosphorylation in the diabetic rat heart. Experimental Physiology, 106, 2235-2247. doi: 10.1113/ep089730

Greenman, A. C., Diffee, G. M., Power, A. S., Wilkins, G. T., Gold, O. M. S., Erickson, J. R., & Baldi, J. C. (2022). Treadmill running increases the calcium sensitivity of myofilaments in diabetic rats. Journal of Applied Physiology. Advance online publication. doi: 10.1152/japplphysiol.00785.2021

Journal - Research Article

Ng, Y. H., Lamberts, R. R., Jones, P. P., Sammut, I. A., Diffee, G. M., Wilkins, G. T., & Baldi, J. C. (2022). Sarco/endoplasmic reticulum calcium ATPase activity is unchanged despite increased myofilament calcium sensitivity in Zucker type 2 diabetic fatty rat heart. Scientific Reports, 12(1), 16904. doi: 10.1038/s41598-022-20520-0

Journal - Research Article

Woodfield, J. C., Clifford, K., Wilson, G. A., Munro, F., & Baldi, J. C. (2022). Short-term high-intensity interval training improves fitness before surgery: A randomised clinical trial. Scandinavian Journal of Medicine & Science in Sports, 32, 856-865. doi: 10.1111/sms.14130

Journal - Research Article

Bell, R. A., Baldi, J. C., & Jones, L. M. (2021). Additional cardiovascular fitness when progressing from moderate- to high-intensity exercise training in previously trained breast cancer survivors. Supportive Care in Cancer, 29, 6645-6650. doi: 10.1007/s00520-021-06259-w

Journal - Research Article

Chiavaroli, V., Hopkins, S. A., Biggs, J. B., Rodrigues, R. O., Seneviratne, S. N., Baldi, J. C., … Derraik, J. G. B. (2021). The associations between maternal BMI and gestational weight gain and health outcomes in offspring at age 1 and 7 years. Scientific Reports, 11, 20865. doi: 10.1038/s41598-021-99869-7

Journal - Research Article

Greenman, A. C., Diffee, G. M., Power, A. S., Wilkins, G. T., Gold, O. M. S., Erickson, J. R., & Baldi, J. C. (2021). Increased myofilament calcium sensitivity is associated with decreased cardiac troponin I phosphorylation in the diabetic rat heart. Experimental Physiology, 106, 2235-2247. doi: 10.1113/ep089730

Journal - Research Article

Jones, L. M., Wilson, R., Stoner, L., & Baldi, J. C. (2021). Arterial stiffness as a cardiovascular risk factor in prostate cancer survivors: A case-control study. Journal of Science in Sport & Exercise, 3(2), 171-178. doi: 10.1007/s42978-019-00036-2

Journal - Research Article

Ng, Y. H., Okolo, C. A., Erickson, J. R., Baldi, J. C., & Jones, P. P. (2021). Protein O-GlcNAcylation in the heart. Acta Physiologica, 233, e13696. doi: 10.1111/apha.13696

Journal - Research Article

Jones, L. M., Stoner, L., Baldi, J. C., & McLaren, B. (2020). Circuit resistance training and cardiovascular health in breast cancer survivors. European Journal of Cancer Care, 29, e13231. doi: 10.1111/ecc.13231

Journal - Research Article

Jones, L. M., Stoner, L., Brown, C., Baldi, J. C., & McLaren, B. (2019). Cardiorespiratory fitness predicts cardiovascular health in breast cancer survivors, independent of body composition, age and time post-treatment completion. Breast Cancer, 26, 729-737. doi: 10.1007/s12282-019-00975-2

Journal - Research Article

Wilson, G. A., Wilkins, G. T., Cotter, J. D., Lamberts, R. R., Lal, S., & Baldi, J. C. (2019). HIIT improves left ventricular exercise response in adults with type 2 diabetes. Medicine & Science in Sports & Exercise, 51(6), 1099-1105. doi: 10.1249/mss.0000000000001897

Journal - Research Article

Chiavaroli, V., Hopkins, S. A., Derraik, J. G. B., Biggs, J. B., Rodrigues, R. O., Brennan, C. H., … Baldi, J. C., … Hofman, P. L. (2018). Exercise in pregnancy: 1-year and 7-year follow-ups of mothers and offspring after a randomized controlled trial. Scientific Reports, 8(1), 12915. doi: 10.1038/s41598-018-30925-5

Journal - Research Article

Daniels, L. J., Wallace, R. S., Nicholson, O. M., Wilson, G. A., McDonald, F. J., Jones, P. P., Baldi, J. C., Lamberts, R. R., & Erickson, J. R. (2018). Inhibition of calcium/calmodulin-dependent kinase II restores contraction and relaxation in isolated cardiac muscle from type 2 diabetic rats. Cardiovascular Diabetology, 17, 89. doi: 10.1186/s12933-018-0732-x

Journal - Research Article

Gusso, S., Pinto, T., Baldi, J. C., Derraik, J. G. B., Cutfield, W. S., Hornung, T., & Hofman, P. L. (2017). Exercise training improves but does not normalize left ventricular systolic and diastolic function in adolescents with type 1 diabetes. Diabetes Care, 40(9), 1264-1272. doi: 10.2337/dc16-2347

Journal - Research Article

Wilson, G. A., Wilkins, G. T., Cotter, J. D., Lamberts, R. R., Lal, S., & Baldi, J. C. (2017). Impaired ventricular filling limits cardiac reserve during submaximal exercise in people with type 2 diabetes. Cardiovascular Diabetology, 16, 160. doi: 10.1186/s12933-017-0644-1

Journal - Research Article

Wilson, G. A., Wilson, L. C., Lamberts, R. R., Majeed, K., Lal, S., Wilkins, G. T., & Baldi, J. C. (2017). β-adrenergic responsiveness in the type 2 diabetic heart: Effects on cardiac reserve. Medicine & Science in Sports & Exercise, 49(5), 907-914. doi: 10.1249/mss.0000000000001184

Journal - Research Article

Wilson, L. C., Peebles, K. C., Hoye, N. A., Manning, P., Sheat, C., Williams, M. J. A., Wilkins, G. T., Wilson, G. A., & Baldi, J. C. (2017). Resting heart rate variability and exercise capacity in Type 1 diabetes. Physiological Reports, 5(8), e13248. doi: 10.14814/phy2.13248

Journal - Research Article

Baldi, J. C., Wilson, G. A., Wilson, L. C., Wilkins, G. T., & Lamberts, R. R. (2016). The type 2 diabetic heart: Its role in exercise intolerance and the challenge to find effective exercise interventions. Sports Medicine, 46, 1605-1617. doi: 10.1007/s40279-016-0542-9

Journal - Research Article

Bussey, C. T., Hughes, G., Saxena, P., Galvin, I. F., Bunton, R. W., Noye, M. K., Coffey, S., Williams, M. J. A., Baldi, J. C., Jones, P. P., & Lamberts, R. R. (2015). Chamber-specific changes in calcium-handling proteins in the type 2 diabetic human heart with preserved ejection fraction. International Journal of Cardiology, 193, 53-55. doi: 10.1016/j.ijcard.2015.05.053

Journal - Research Article

Green, S., Egaña, M., Baldi, J. C., Lamberts, R., & Regensteiner, J. G. (2015). Cardiovascular control during exercise in type 2 diabetes mellitus. Journal of Diabetes Research, 2015, 654204. doi: 10.1155/2015/654204

Journal - Research Article

Thaung, H. P. A., Baldi, J. C., Wang, H.-Y., Hughes, G., Cook, R. F., Bussey, C. T., Sheard, P. W., Bahn, A., Jones, P. P., Schwenke, D. O., & Lamberts, R. R. (2015). Increased efferent cardiac sympathetic nerve activity and defective intrinsic heart rate regulation in type 2 diabetes. Diabetes, 64(8), 2944-2956. doi: 10.2337/db14-0955

Journal - Research Article

Baldi, J. C., Dacey, M. J., Lee, M. J., & Coast, J. R. (2014). Prior maximal exercise decreases pulmonary diffusing capacity during subsequent exercise. International Journal of Sports Medicine, 35(12), 982-986. doi: 10.1055/s-0034-1372635

Journal - Research Article

Francois, M. E., Baldi, J. C., Manning, P. J., Lucas, S. J. E., Hawley, J. A., Williams, M. J. A., & Cotter, J. D. (2014). ‘Exercise snacks’ before meals: A novel strategy to improve glycaemic control in individuals with insulin resistance. Diabetologia, 57(7), 1437-1445. doi: 10.1007/s00125-014-3244-6

Journal - Research Article

Hoye, N. A., Baldi, J. C., Putt, T. L., Schollum, J. B., Wilkins, G. T., & Walker, R. J. (2014). Endovascular renal denervation: A novel sympatholytic with relevance to chronic kidney disease. Clinical Kidney Journal, 7(1), 3-10. doi: 10.1093/ckj/sft130

Journal - Research Article

Lamberts, R. R., Lingam, S. J., Wang, H.-Y., Bollen, I. A. E., Hughes, G., Galvin, I. F., Bunton, R. W., Bahn, A., Katare, R., Baldi, J. C., Williams, M. J. A., Saxena, P., Coffey, S., & Jones, P. P. (2014). Impaired relaxation despite upregulated calcium-handling protein atrial myocardium from type 2 diabetic patients with preserved ejection fraction. Cardiovascular Diabetology, 13, 72. doi: 10.1186/1475-2840-13-72

Journal - Research Article

Pinto, T. E., Gusso, S., Hofman, P. L., Derraik, J. G. B., Hornung, T. S., Cutfield, W. S., & Baldi, J. C. (2014). Systolic and diastolic abnormalities reduce the cardiac response to exercise in adolescents with type 2 diabetes. Diabetes Care, 37(5), 1439-1446. doi: 10.2337/dc13-2031

Journal - Research Article

Jones, L. M., Stoner, L., Brown, C., Baldi, C., & McLaren, B. (2013). Cardiovascular disease among breast cancer survivors: The call for a clinical vascular health toolbox. Breast Cancer Research & Treatment, 142(3), 645-653. doi: 10.1007/s10549-013-2766-9

Journal - Research Article

Carrick-Ranson, G., Doughty, R. N., Whalley, G. A., Walsh, H. J., Gamble, G. D., & Baldi, J. C. (2012). The larger exercise stroke volume in endurance-trained men does not result from increased left ventricular early or late inflow or tissue velocities. Acta Physiologica, 205(4), 520-531. doi: 10.1111/j.1748-1716.2012.02430.x

Journal - Research Article

Gusso, S., Pinto, T. E., Baldi, J. C., Robinson, E., Cutfield, W. S., & Hofman, P. L. (2012). Diastolic function is reduced in adolescents with type 1 diabetes in response to exercise. Diabetes Care, 35(10), 2089-2094. doi: 10.2337/dc11-2331

Journal - Research Article

Wimer, G. S., & Baldi, J. C. (2012). Limb-specific training affects exercise hyperemia but not sympathetic vasoconstriction. European Journal of Applied Physiology, 112(11), 3819-3828.

Journal - Research Article

Hopkins, S. A., Baldi, J. C., Cutfield, W. S., McCowan, L., & Hofman, P. L. (2011). Effects of exercise training on maternal hormonal changes in pregnancy. Clinical Endocrinology, 74(4), 495-500. doi: 10.1111/j.1365-2265.2010.03964.x

Journal - Research Article

Wheatley, C. M., Baldi, J. C., Cassuto, N. A., Foxx-Lupo, W. T., & Snyder, E. M. (2011). Glycemic control influences lung membrane diffusion and oxygen saturation in exercise-trained subjects with type 1 diabetes: Alveolar-capillary membrane conductance in type 1 diabetes. European Journal of Applied Physiology, 111(3), 567-578. doi: 10.1007/s00421-010-1663-8

Journal - Research Article

Baldi, J. C., & Hofman, P. L. (2010). Does careful glycemic control improve aerobic capacity in subjects with type 1 diabetes? Exercise & Sport Sciences Reviews, 38(4), 161-167. doi: 10.1097/JES.0b013e3181f4501e

Journal - Research Article

Baldi, J. C., Cassuto, N. A., Foxx-Lupo, W. T., Wheatley, C. M., & Snyder, E. M. (2010). Glycemic status affects cardiopulmonary exercise response in athletes with type 1 diabetes. Medicine & Science in Sports & Exercise, 42(8), 1454-1459. doi: 10.1249/MSS.0b013e3181d1fdb3

Journal - Research Article

Hopkins, S. A., Baldi, J. C., Cutfield, W. S., McCowan, L., & Hofman, P. L. (2010). Exercise training in pregnancy reduces offspring size without changes in maternal insulin sensitivity. Journal of Clinical Endocrinology & Metabolism, 95(5), 2080-2088. doi: 10.1210/jc.2009-2255

Journal - Research Article

Lalande, S., Hofman, P., & Baldi, J. C. (2010). Effect of reduced total blood volume on left ventricular volumes and kinetics in type 2 diabetes. Acta Physiologica, 199(1), 23-30. doi: 10.1111/j.1748-1716.2010.02081.x

Journal - Research Article

Whalley, G. A., Gusso, S., Hofman, P., Cutfield, W., Poppe, K. K., Doughty, R. N., & Baldi, J. C. (2009). Structural and functional cardiac abnormalities in adolescent girls with poorly controlled type 2 diabetes. Diabetes Care, 32(5), 883-888. doi: 10.2337/dc08-2005

Journal - Research Article

Gusso, S., Hofman, P., Lalande, S., Cutfield, W., Robinson, E., & Baldi, J. C. (2008). Impaired stroke volume and aerobic capacity in female adolescents with type 1 and type 2 diabetes mellitus. Diabetologia, 51(7), 1317-1320. doi: 10.1007/s00125-008-1012-1

Journal - Research Article

Lalande, S., Gusso, S., Hofman, P. L., & Baldi, J. C. (2008). Reduced leg blood flow during submaximal exercise in type 2 diabetes. Medicine & Science in Sports & Exercise, 48(4), 612-617. doi: 10.1249/MSS.0b013e318161aa99

Journal - Research Article

Baldi, J. C., Lalande, S., Carrick-Ranson, G., & Johnson, B. D. (2007). Postural differences in hemodynamics and diastolic function in healthy older men. European Journal of Applied Physiology, 99(6), 651-657. doi: 10.1007/s00421-006-0384-5

Journal - Research Article

Hammett, C. J. K., Prapavessis, H., Baldi, J. C., Ameratunga, R., Schoenbeck, U., Varo, N., … Stewart, R. A. H. (2007). Variation in blood levels of inflammatory markers related and unrelated to smoking cessation in women. Preventive Cardiology, 10(2), 68-75. doi: 10.1111/j.1520-037X.2007.05957.x

Journal - Research Article

Lalande, S., & Baldi, J. C. (2007). Left ventricular mass in elite Olympic weight lifters. American Journal of Cardiology, 100(7), 1177-1180. doi: 10.1016/j.amjcard.2007.05.036

Journal - Research Article

Prapavessis, H., Cameron, L., Baldi, J. C., Robinson, S., Borrie, K., Harper, T., & Grove, J. R. (2007). The effects of exercise and nicotine replacement therapy on smoking rates in women. Addictive Behaviors, 32(7), 1416-1432. doi: 10.1016/j.addbeh.2006.10.005

Journal - Research Article

Baldi, J. C., Aoina, J. L., Whalley, G. A., Carrick-Ranson, G., Walsh, H., O'Shaughnessy, H., … Doughty, R. N. (2006). The effect of type 2 diabetes on diastolic function. Medicine & Science in Sports & Exercise, 38(8), 1384-1388. doi: 10.1249/01.mss.0000228954.90591.95

Journal - Research Article

Hammett, C. J. K., Prapavessis, H., Baldi, J. C., Varo, N., Schoenbeck, U., Ameratunga, R., … Stewart, R. A. H. (2006). Effects of exercise training on 5 inflammatory markers associated with cardiovascular risk. American Heart Journal, 151(2), 367 e7-367 e16. doi: 10.1016/j.ahj.2005.08.009

Journal - Research Article

Whalley, G. A., Doughty, R. N., Gamble, G. D., Oxenham, H. C., Walsh, H. J., Reid, I. R., & Baldi, J. C. (2004). Association of fat-free mass and training status with left ventricular size and mass in endurance-trained athletes. JACC, 44(4), 892-896. doi: 10.1016/j.jacc.2004.04.051

Journal - Research Article

Baldi, J. C., McFarlane, K., Oxenham, H. C., Whalley, G. A., Walsh, H. J., & Doughty, R. N. (2003). Left ventricular diastolic filling and systolic function of young and older trained and untrained men. Journal of Applied Physiology, 95, 2570-2575. doi: 10.1152/japplphysiol.00441.2003

Journal - Research Article

Woodfield, J. C., Baldi, J. C., & Clifford, K. (2019). What is the minimal dose of HIIT required to achieve pre-operative benefit. Scandinavian Journal of Medicine & Science in Sports, 29, 1841. doi: 10.1111/sms.13538

Journal - Research Other

Woodfield, J., Zacharias, M., Wilson, G., Munro, F., Thomas, K., Gray, A., & Baldi, J. (2018). Protocol, and practical challenges, for a randomised controlled trial comparing the impact of high intensity interval training against standard care before major abdominal surgery: Study protocol for a randomised controlled trial. Trials, 19(1), 331. doi: 10.1186/s13063-018-2701-9

Journal - Research Other

Baldi, J. C., Manning, P. J., Hofman, P. L., & Walker, R. J. (2013). Comment on: TODAY Study Group. Effects of Metformin, Metformin plus Rosiglitazone, and Metformin plus lifestyle on insulin sensitivity and β-cell function in TODAY. Diabetes Care 2013;36:1749-1757 [Comment]. Diabetes Care, 36, e223. doi: 10.2337/dc13-1426

Journal - Research Other

Whalley, G. A., Doughty, R. N., & Baldi, J. C. (2005). Detection of pathologic or physiologic left ventricular remodeling in athletes: Reply. JACC, 45(10), 1731. doi: 10.1016/j.jacc.2005.02.048

Journal - Research Other

More publications...