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DSM staff profile

Professor Patrick Manning

PositionClinical Professor of Medicine; Consultant Endocrinologist; Director, Endocrinology Research Group
DepartmentDepartment of Medicine (Dunedin)
QualificationsBHB MB ChB MMedSci FRACP
Research summaryEndocrinology and diabetes.

Research

The Endocrinology Research Group's major focus relates to clinical trials in all areas of endocrinology including diabetes, general endocrinology, and metabolism. A key area of research focus is the link between obesity and insulin resistance.

The group has published widely on the effect of meal composition on postprandial inflammation and is involved in clinical trials in obesity, type 2 diabetes and osteoporosis.

The group consists of Prof Patrick Manning, Dr Wayne Sutherland, Dr Ted Nye, and is assisted by three research nurses (Anne Ryalls, Liz Berry and Gavin Hendry). In addition the group has collaborative projects with other members of the Department of Medicine, as well as other researchers both nationally and internationally.

Opportunities

If you have research interest in clinical endocrinology including diabetes and/or obesity and have either a tertiary science degree or a medical degree then feel free to make contact with Prof Patrick Manning to find out if there are any current research opportunities available within the research group.

Otago Kidney Research

Publications

Bellae Papannarao, J., Schwenke, D. O., Manning, P., & Katare, R. (2021). Upregulated miR-200c is associated with downregulation of the functional receptor for severe acute respiratory syndrome coronavirus 2 ACE2 in individuals with obesity [Brief communication]. International Journal of Obesity. Advance online publication. doi: 10.1038/s41366-021-00984-2

Meredith-Jones, K., Taylor, R., Brown, R., Cooke, R., Vlietstra, L., Manning, P., Poulton, R., & Haszard, J. (2021). Age- and sex-specific visceral fat reference cutoffs and their association with cardio-metabolic risk. International Journal of Obesity. Advance online publication. doi: 10.1038/s41366-021-00743-3

Chandrasekera, D. N. K., Neale, J. P. H., van Hout, I., Rawal, S., Coffey, S., Jones, G. T., … Manning, P., Williams, M. J. A., & Katare, R. (2020). Upregulation of microRNA-532 enhances cardiomyocyte apoptosis in the diabetic heart. Apoptosis, 25(5-6), 388-399. doi: 10.1007/s10495-020-01609-1

Leong, S. L., Glue, P., Manning, P., Vanneste, S., Lim, L. J., Mohan, A., & De Ridder, D. (2020). Anterior cingulate cortex implants for alcohol addiction: A feasibility study. Neurotherapeutics, 17, 1287-1299. doi: 10.1007/s13311-020-00851-4

Manning, P., Munasinghe, P. E., Bellae Papannarao, J., Gray, A. R., Sutherland, W., & Katare, R. (2019). Acute weight loss restores dysregulated circulating microRNAs in obese individuals. Journal of Clinical Endocrinology & Metabolism, 104(4), 1239-1248. doi: 10.1210/jc.2018-00684

De Ridder, D., Manning, P., Cape, G., Vanneste, S., Langguth, B., & Glue, P. (2016). Pathophysiology-based neuromodulation for addictions: An overview. In V. R. Preedy (Ed.), Neuropathology of drug addictions and substance misuse (Vol. 1: Foundations of understanding, tobacco, alcohol, cannabinoids and opioids). (pp. 14-24). London: Elsevier. doi: 10.1016/B978-0-12-800213-1.00002-X

Chapter in Book - Research

Meredith-Jones, K., Taylor, R., Brown, R., Cooke, R., Vlietstra, L., Manning, P., Poulton, R., & Haszard, J. (2021). Age- and sex-specific visceral fat reference cutoffs and their association with cardio-metabolic risk. International Journal of Obesity. Advance online publication. doi: 10.1038/s41366-021-00743-3

Journal - Research Article

Chandrasekera, D. N. K., Neale, J. P. H., van Hout, I., Rawal, S., Coffey, S., Jones, G. T., … Manning, P., Williams, M. J. A., & Katare, R. (2020). Upregulation of microRNA-532 enhances cardiomyocyte apoptosis in the diabetic heart. Apoptosis, 25(5-6), 388-399. doi: 10.1007/s10495-020-01609-1

Journal - Research Article

Leong, S. L., Glue, P., Manning, P., Vanneste, S., Lim, L. J., Mohan, A., & De Ridder, D. (2020). Anterior cingulate cortex implants for alcohol addiction: A feasibility study. Neurotherapeutics, 17, 1287-1299. doi: 10.1007/s13311-020-00851-4

Journal - Research Article

Manning, P., Munasinghe, P. E., Bellae Papannarao, J., Gray, A. R., Sutherland, W., & Katare, R. (2019). Acute weight loss restores dysregulated circulating microRNAs in obese individuals. Journal of Clinical Endocrinology & Metabolism, 104(4), 1239-1248. doi: 10.1210/jc.2018-00684

Journal - Research Article

Leong, S. L., De Ridder, D., Vanneste, S., Sutherland, W., Ross, S., & Manning, P. (2018). High definition transcranial pink noise stimulation of anterior cingulate cortex on food craving: An explorative study. Appetite, 120, 673-678. doi: 10.1016/j.appet.2017.10.034

Journal - Research Article

Leong, S. L., Vanneste, S., Lim, J., Smith, M., Manning, P., & De Ridder, D. (2018). A randomised, double-blind, placebo-controlled parallel trial of closed-loop infraslow brain training in food addiction. Scientific Reports, 8, 11659. doi: 10.1038/s41598-018-30181-7

Journal - Research Article

Ma, Z. F., Venn, B. J., Manning, P. J., Cameron, C. M., & Skeaff, S. A. (2018). The sensitivity and specificity of thyroglobulin concentration using repeated measures of urinary iodine excretion. European Journal of Nutrition, 57(4), 1313-1320. doi: 10.1007/s00394-017-1410-6

Journal - Research Article

Manning, P. J., Grattan, D., Merriman, T., Manning, T., Williams, S., & Sutherland, W. (2018). Pharmaceutical interventions for weight-loss maintenance: No effect from cabergoline. International Journal of Obesity, 42, 1871-1879. doi: 10.1038/s41366-018-0165-3

Journal - Research Article

Rawal, S., Munasinghe, E. P., Nagesh, P. T., Lew, J. K. S., Jones, G. T., Williams, M. J. A., Davis, P., Bunton, R. W., Galvin, I. F., Manning, P., Lamberts, R. R., & Katare, R. (2017). Downregulation of miR-15a/b accelerates fibrotic remodelling in the Type-2 diabetic human and mouse heart. Clinical Science, 131(9), 847-863. doi: 10.1042/cs20160916

Journal - Research Article

Rawal, S., Munasinghe, P. E., Shindikar, A., Paulin, J., Cameron, V., Manning, P., Williams, M. J. A., Jones, G. T., Bunton, R., Galvin, I., & Katare, R. (2017). Down-regulation of proangiogenic microRNA-126 and microRNA-132 are early modulators of diabetic cardiac microangiopathy. Cardiovascular Research, 113(1), 90-101. doi: 10.1093/cvr/cvw235

Journal - Research Article

Wilson, L. C., Peebles, K. C., Hoye, N. A., Manning, P., Sheat, C., Williams, M. J. A., Wilkins, G. T., Wilson, G. A., & Baldi, J. C. (2017). Resting heart rate variability and exercise capacity in Type 1 diabetes. Physiological Reports, 5(8), e13248. doi: 10.14814/phy2.13248

Journal - Research Article

De Ridder, D., Manning, P., Leong, S. L., Ross, S., & Vanneste, S. (2016). Allostasis in health and food addiction. Scientific Reports, 6, 37126. doi: 10.1038/srep37126

Journal - Research Article

De Ridder, D., Manning, P., Leong, S. L., Ross, S., Sutherland, W., Horwath, C., & Vanneste, S. (2016). The brain, obesity and addiction: An EEG neuroimaging study. Scientific Reports, 6, 34122. doi: 10.1038/srep34122

Journal - Research Article

De Ridder, D., Vanneste, S., Gillett, G., Manning, P., Glue, P., & Langguth, B. (2016). Psychosurgery reduces uncertainty and increases free will? A review. Neuromodulation, 19, 239-248. doi: 10.1111/ner.12405

Journal - Research Article

Ma, Z. F., Venn, B. J., Manning, P. J., Cameron, C. M., & Skeaff, S. A. (2016). Iodine supplementation of mildly iodine-deficient adults lowers thyroglobulin: A randomized controlled trial. Journal of Clinical Endocrinology & Metabolism, 101(4), 1737-1744. doi: 10.1210/jc.2015-3591

Journal - Research Article

Williams, K. H., Sullivan, D. R., Nicholson, G. C., George, J., Jenkins, A. J., Januszewski, A. S., … Manning, P., … Keech, A. C. (2016). Opposite associations between alanine aminotransferase and γ-glutamyl transferase levels and all-cause mortality in type 2 diabetes: Analysis of the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study. Metabolism, 65(5), 783-793. doi: 10.1016/j.metabol.2015.12.008

Journal - Research Article

Evans, M. C., Clark, V. W., Manning, P. J., De Ridder, D., & Reynolds, J. N. J. (2015). Optimizing deep brain stimulation of the nucleus accumbens in a reward preference rat model. Neuromodulation, 18(7), 531-541. doi: 10.1111/ner.12339

Journal - Research Article

Holdaway, I. M., Hunt, P., Manning, P., Cutfield, W., Gamble, G., Ninow, N., … Metcalfe, S. (2015). Three-year experience with access to nationally funded growth hormone (GH) replacement for GH-deficient adults. Clinical Endocrinology, 83(1), 85-90. doi: 10.1111/cen.12691

Journal - Research Article

Francois, M. E., Baldi, J. C., Manning, P. J., Lucas, S. J. E., Hawley, J. A., Williams, M. J. A., & Cotter, J. D. (2014). ‘Exercise snacks’ before meals: A novel strategy to improve glycaemic control in individuals with insulin resistance. Diabetologia, 57(7), 1437-1445. doi: 10.1007/s00125-014-3244-6

Journal - Research Article

Rawal, S., Manning, P., & Katare, R. (2014). Cardiovascular microRNAs: As modulators and diagnostic biomarkers of diabetic heart disease. Cardiovascular Diabetology, 13, 44. doi: 10.1186/1475-2840-13-44

Journal - Research Article

Latta, L., Tordoff, D., Manning, P., & Dent, J. (2013). Enhancing clinical skill development through an Ambulatory Medicine Teaching Programme: An evaluation study. Medical Teacher, 35(8), 648-654. doi: 10.3109/0142159X.2013.801553

Journal - Research Article

Manning, P. J., Sutherland, W. H. F., Williams, S. M., de Jong, S. A., & Hendry, G. P. (2013). Oral but not intravenous glucose acutely decreases circulating interleukin-6 concentrations in overweight individuals. PLoS ONE, 8(6), e66395. doi: 10.1371/journal.pone.0066395

Journal - Research Article

Manning, P. J., Sutherland, W. H. F., Williams, S. M., Walker, R. J., Berry, E. A., De Jong, S. A., & Ryalls, A. R. (2013). The effect of lipoic acid and vitamin E therapies in individuals with the metabolic syndrome. Nutrition, Metabolism & Cardiovascular Diseases, 23(6), 543-549. doi: 10.1016/j.numecd.2011.11.006

Journal - Research Article

Manning, P. J., De Jong, S. A., Ryalls, A. R., & Sutherland, W. H. F. (2012). Paraoxonase 1 activity in chylomicrons and VLDL: The effect of type 2 diabetes and meals rich in saturated fat and oleic acid. Lipids, 47(3), 259-267. doi: 10.1007/s11745-011-3640-3

Journal - Research Article

Silverman, S. L., Chines, A. A., Kendler, D. L., Kung, A. W. C., Teglbjærg, C. S., Felsenberg, D., … for the Bazedoxifene Study Group, including Manning, P. (2012). Sustained efficacy and safety of bazedoxifene in preventing fractures in postmenopausal women with osteoporosis: Results of a 5-year, randomized, placebo-controlled study. Osteoporosis International, 23(1), 351-363. doi: 10.1007/s00198-011-1691-1

Journal - Research Article

Vos, F. E., Schollum, J. B., Coulter, C. V., Manning, P. J., Duffull, S. B., & Walker, R. J. (2012). Assessment of markers of glycaemic control in diabetic patients with chronic kidney disease using continuous glucose monitoring. Nephrology, 17(2), 182-188. doi: 10.1111/j.1440-1797.2011.01517.x

Journal - Research Article

Davis, T. M. E., Ting, R. D., Best, J. D., Donoghoe, M. W., Drury, P. L., Sullivan, D. R., … on behalf of the FIELD Study Investigators, including Manning, P. (2011). Effects of fenofibrate on renal function in patients with type 2 diabetes mellitus: The fenofibrate intervention and event lowering in diabetes (FIELD) study. Diabetologia, 54(2), 280-290. doi: 10.1007/s00125-010-1951-1

Journal - Research Article

Scott, R., Donoghoe, M., Watts, G. F., O'Brien, R., Pardy, C., Taskinen, M.-R., … Manning, P., … Keech, A. C. (2011). Impact of metabolic syndrome and its components on cardiovascular disease event rates in 4900 patients with type 2 diabetes assigned to placebo in the FIELD randomised trial. Cardiovascular Diabetology, 10, 102. doi: 10.1186/1475-2840-10-102

Journal - Research Article

Slade, H., Williams, S. M., Manning, P. J., & Walker, R. J. (2011). High-risk diabetic nephropathy patients: The outcome of evidence-based clinical practice in an outpatient clinic. Diabetes Research & Clinical Practice, 92(3), 356-360. doi: 10.1016/j.diabres.2011.02.022

Journal - Research Article

Sosenko, J. M., Mahon, J., Rafkin, L., Lachin, J. M., Krause-Steinrauf, H., Krischer, J. P., … and the Diabetes Prevention Trial-Type 1 and TrialNet Study Groups, including Manning, P. (2011). A comparison of the baseline metabolic profiles between Diabetes Prevention Trial-Type 1 and TrialNet Natural History study participants. Pediatric Diabetes, 12(2), 85-90. doi: 10.1111/j.1399-5448.2010.00662.x

Journal - Research Article

Sosenko, J. M., Skyler, J. S., Mahon, J., Krischer, J. P., Beam, C. A., Boulware, D. C., … the Type 1 Diabetes TrialNet and Diabetes Prevention Trial-Type 1 Study Groups, including Manning, P. (2011). Validation of the Diabetes Prevention Trial-Type 1 risk score in the TrialNet Natural History study. Diabetes Care, 34(8), 1785-1787. doi: 10.2337/dc11-0641

Journal - Research Article

Sosenko, J. M., Skyler, J. S., Palmer, J. P., Krischer, J. P., Cuthbertson, D., Yu, L., … Diabetes Prevention Trial-Type 1, and Type 1 Diabetes TrialNet Study Groups, including Manning, P. (2011). A longitudinal study of GAD65 and ICA512 autoantibodies during the progression to type 1 diabetes in Diabetes Prevention Trial-Type 1 (DPT-1) participants. Diabetes Care, 34(11), 2435-2437. doi: 10.2337/dc11-0981

Journal - Research Article

Sullivan, D., Forder, P., Simes, J., Whiting, M., Kritharides, L., Merrifield, A., … for the FIELD Study Investigators, including Manning, P. (2011). Associations between the use of metformin, sulphonylureas, or diet alone and cardiovascular outcomes in 6005 people with type 2 diabetes in the FIELD study. Diabetes Research & Clinical Practice, 94(2), 284-290. doi: 10.1016/j.diabres.2011.07.028

Journal - Research Article

Vehik, K., Beam, C. A., Mahon, J. L., Schatz, D. A., Haller, M. J., Sosenko, J. M., … for the TrialNet Natural History Study Group, including Manning, P. (2011). Development of autoantibodies in the TrialNet Natural History study. Diabetes Care, 34(9), 1897-1901. doi: 10.2337/dc11-0560

Journal - Research Article

Vehik, K., Cuthbertson, D., Ruhlig, H., Schatz, D. A., Peakman, M., Krischer, J. P., for the DPT-1 and TrialNet Study Groups, including Manning, P. (2011). Long-term outcome of individuals treated with oral insulin: Diabetes Prevention Trial-Type 1 (DPT-1) oral insulin trial. Diabetes Care, 34(7), 1585-1590. doi: 10.2337/dc11-0523

Journal - Research Article

Vos, F. E., Manning, P. J., Sutherland, W. H. F., Schollum, J. B., & Walker, R. J. (2011). Anti-inflammatory effect of an insulin infusion in patients on maintenance haemodialysis: A randomized controlled pilot study. Nephrology, 16(1), 68-75. doi: 10.1111/j.1440-1797.2010.01329.x

Journal - Research Article

Simes, J., Voysey, M., O'Connell, R., Glasziou, P., Best, J. D., Scott, R., … for the FIELD Study Investigators, including Manning, P. (2010). A novel method to adjust efficacy estimates for uptake of other active treatments in long-term clinical trials. PLoS ONE, 5(1), e8580. doi: 10.1371/journal.pone.0008580

Journal - Research Article

Taskinen, M.-R., Barter, P. J., Ehnholm, C., Sullivan, D. R., Mann, K., Simes, J., … on behalf of the FIELD Study Investigators, including Manning, P. (2010). Ability of traditional lipid ratios and apolipoprotein ratios to predict cardiovascular risk in people with type 2 diabetes. Diabetologia, 53(9), 1846-1855. doi: 10.1007/s00125-010-1806-9

Journal - Research Article

Taylor, R. W., Brooking, L., Williams, S. M., Manning, P. J., Sutherland, W. H., Coppell, K. J., Tipene-Leach, D., Dale, K. S., McAuley, K. A., & Mann, J. I. (2010). Body mass index and waist circumference cutoffs to define obesity in indigenous New Zealanders. American Journal of Clinical Nutrition, 92, 390-397. doi: 10.3945/ajcn.2010.29317

Journal - Research Article

Herold, K. C., Brooks-Worrell, B., Palmer, J., Dosch, H. M., Peakman, M., Gottlieb, P., … and the Type 1 Diabetes TrialNet Research Group, including Manning, P. (2009). Validity and reproducibility of measurement of islet autoreactivity by T-cell assays in subjects with early type 1 diabetes. Diabetes, 58(11), 2588-2595. doi: 10.2337/db09-0249

Journal - Research Article

Mahon, J. L., Sosenko, J. M., Rafkin-Mervis, L., Krause-Steinrauf, H., Lachin, J. M., Thompson, C., … for the TrialNet Natural History Committee, and Type 1 Diabetes TrialNet Study Group, including Manning, P. (2009). The TrialNet Natural History study of the development of type 1 diabetes: Objectives, design, and initial results. Pediatric Diabetes, 10(2), 97-104. doi: 10.1111/j.1399-5448.2008.00464.x

Journal - Research Article

Rajamani, K., Colman, P. G., Li, L. P., Best, J. D., Voysey, M., D'Emden, M. C., … on behalf of the FIELD Study Investigators, including Manning, P. (2009). Effect of fenofibrate on amputation events in people with type 2 diabetes mellitus (FIELD study): A prespecified analysis of a randomised controlled trial. Lancet, 373(9677), 1780-1788. doi: 10.1016/S0140-6736(09)60698-X

Journal - Research Article

Scott, R., O'Brien, R., Fulcher, G., Pardy, C., D'Emden, M., Tse, D., … on behalf of the Fenofibrate Intervention and Event Lowering in Diabete (FIELD) Study Investigators, including Manning, P. (2009). Effects of fenofibrate treatment on cardiovascular disease risk in 9,795 individuals with type 2 diabetes and various components of the metabolic syndrome. Diabetes Care, 32(3), 493-498. doi: 10.2337/dc08-1543

Journal - Research Article

Taskinen, M.-R., Sullivan, D. R., Ehnholm, C., Whiting, M., Zannino, D., Simes, R. J., … for the FIELD Study Investigators, including Manning, P. (2009). Relationships of HDL cholesterol, ApoA-I, and ApoA-II with homocysteine and creatinine in patients with type 2 diabetes treated with fenofibrate. Arteriosclerosis, Thrombosis, & Vascular Biology, 29, 950-955. doi: 10.1161/ATVBAHA.108.178228

Journal - Research Article

Greenbaum, C., Mandrup-Poulsen, T., McGee, P. F., Battelino, T., Haastert, B., Ludvigsson, J., … the Type 1 Diabetes TrialNet Research Group, and the European C-Peptide Trial Study Group, including Manning, P. (2008). Mixed-meal tolerance test versus glucagon stimulation test for the assessment of β-cell function in therapeutic trials in type 1 diabetes. Diabetes Care, 31(10), 1966-1971. doi: 10.2337/dc07-2451

Journal - Research Article

Manning, P. J., Sutherland, W. H. F., McGrath, M. M., de Jong, S. A., Walker, R. J., & Williams, M. J. A. (2008). Postprandial cytokine concentrations and meal composition in obese and lean women. Obesity, 16(9), 2046-2052. doi: 10.1038/oby.2008.334

Journal - Research Article

Manning, P. J., Sutherland, W. H. F., Walker, R. J., de Jong, S. A., & Berry, E. A. (2008). The effect of glucose ingestion on inflammation and oxidative stress in obese individuals. Metabolism, 57, 1345-1349.

Journal - Research Article

Manning, P. J., Sutherland, W. H. F., Walker, R. J., Williams, S. M., de Jong, S. A., & Berry, E. A. (2008). The effect of rosiglitazone on oxidative stress and insulin resistance in overweight individuals. Diabetes Research & Clinical Practice, 81, 209-215.

Journal - Research Article

Helge, J. W., Rehrer, N. J., Pilegaard, H., Manning, P., Lucas, S. J. E., Gerrard, D. F., & Cotter, J. D. (2007). Increased fat oxidation and regulation of metabolic genes with ultraendurance exercise. Acta Physiologica, 191, 77-86.

Journal - Research Article

Keech, A. C., Mitchell, P., Summanen, P. A., O'Day, J., Davis, T. M. E., Moffitt, M. S., … for the FIELD Study Investigators, including Manning, P. (2007). Effect of fenofibrate on the need for laser treatment for diabetic retinopathy (FIELD study): A randomised controlled trial. Lancet, 370(9600), 1687-1697. doi: 10.1016/S0140-6736(07)61607-9

Journal - Research Article

Sutherland, W. H. F., Manning, P. J., Walker, R. J., de Jong, S. A., Ryalls, A. R., & Berry, E. A. (2007). Vitamin E supplementation and plasma 8-isoprostane and adiponectin in overweight subjects. Obesity, 15(2), 386-391. doi: 10.1038/oby.2007.546

Journal - Research Article

Coppell, K. J., Anderson, K., Williams, S., Manning, P., & Mann, J. (2006). Evaluation of diabetes care in the Otago region using a diabetes register, 1998-2003. Diabetes Research & Clinical Practice, 71, 345-352.

Journal - Research Article

Florkowski, C. M., Brownlie, B. E. W., Croxson, M. S., Manning, P., Farrand, S., Smith, G., … George, P. M. (2006). Thyroid hormone resistance: The role of mutational analysis. Internal Medicine Journal, 36, 738-741.

Journal - Research Article

Adams, D. D., Knight, J. G., Manning, P., & Smith, G. (2005). An informative case of Graves' disease with implications for schizophrenia. Journal of Clinical & Laboratory Immunology, 53, 13-25.

Journal - Research Article

Goulding, A., Jones, I. E., Williams, S. M., Grant, A. M., Taylor, R. W., Manning, P. J., & Langley, J. (2005). First fracture is associated with increased risk of new fractures during growth. Journal of Pediatrics, 146, 286-288.

Journal - Research Article

Markou, A., Manning, P., Kaya, B., Datta, S. N., Bomanji, J. B., & Conway, G. S. (2005). [18F]fluoro-2-deoxy-D-glucose ([18F]FDG) positron emission tomography imaging of thymic carcinoid tumor presenting with recurrent Cushing's syndrome. European Journal of Endocrinology, 152(4), 521-525.

Journal - Research Article

O'Connell, R., Parkin, L., Manning, P., Bell, D., Herbison, P., & Holmes, J. (2005). A cluster of thyrotoxicosis associated with consumption of a soy milk product. Australian & New Zealand Journal of Public Health, 29(6), 511-512. doi: 10.1111/j.1467-842X.2005.tb00240.x

Journal - Research Article

Manning, P. J., Sutherland, W. H., Hendry, G., de Jong, S. A., McGrath, M., & Williams, S. M. (2004). Changes in circulating postprandial proinflammatory cytokine concentrations in diet-controlled type 2 diabetes and the effect of ingested fat. Diabetes Care, 27(10), 2509-2511.

Journal - Research Article

Manning, P. J., Sutherland, W. H., Walker, R. J., Williams, S. M., de Jong, S. A., Ryalls, A. R., & Berry, E. A. (2004). Effect of high-dose vitamin E on insulin resistance and associated parameters in overweight subjects. Diabetes Care, 27(9), 2166-2171.

Journal - Research Article

Hall, R. J., Merriman, M. E., Green, R. A., Markham, V. H., Smyth, D. J., Heward, J. M., … Braithwaite, A., … Darlow, B. A., … Harrison, A. A., Highton, J., Hunt, P. J., Manning, P. J., … Scott, R. S., Taylor, B. J., Willis, J., … Merriman, T. R. (2003). The Deleted in Colorectal Carcinoma (DCC) gene 201 R → G polymorphism: No evidence for genetic association with autoimmune disease. European Journal of Human Genetics, 11, 840-844.

Journal - Research Article

Manning, P. J., Espiner, E. A., Yoon, K., Drury, P. L., Holdaway, I. M., & Bowers, A. J. (2003). An unusual cause of hyperinsulinaemic hypoglycaemia syndrome. Diabetic Medicine, 20, 772-776.

Journal - Research Article

Manning, P. J., Sutherland, W. H. F., Allum, A. R., de Jong, S. A., & Jones, S. (2003). HRT does not improve urinary albumen excretion in postmenopausal diabetic women. Diabetes Research & Clinical Practice, 60(1), 33-39.

Journal - Research Article

Coppell, K., & Manning, P. J. (2002). Establishing a regional diabetes register and a description of the registered population after one year. New Zealand Medical Journal, 115(1160), U146. Retrieved from http://www.nzma.org.nz/journal/

Journal - Research Article

Goulding, A., Taylor, R. W., Jones, I. E., Manning, P. J., & Williams, S. M. (2002). Spinal overload: A concern for obese children and adolescents? Osteoporosis International, 13, 835-840.

Journal - Research Article

Jones, I. E., Taylor, R. W., Williams, S. M., Manning, P. J., & Goulding, A. (2002). Four-year gain in bone mineral in girls with and without past forearm fractures: A DXA study. Journal of Bone & Mineral Research, 17(6), 1065-1072.

Journal - Research Article

Manning, P. J., Sutherland, W. H. F., Allum, A. R., de Jong, S. A., & Jones, S. D. (2002). The effect of hormone replacement therapy on inflammation-sensitive proteins in post-menopausal women with Type 2 diabetes. Diabetic Medicine, 19(10), 847-852. doi: 10.1046/j.1464-5491.2002.00808.x

Journal - Research Article

Goulding, A., Jones, I. E., Taylor, R. W., Williams, S. M., & Manning, P. J. (2001). Bone mineral density and body composition in boys with distal forearm fractures: A dual-energy x-ray absorptiometry study. Journal of Pediatrics, 139(4), 509-515.

Journal - Research Article

Hip Intervention Program Study, & Manning, P. J. (2001). Effect of risedronate on the risk of hip fracture in elderly women. New England Journal of Medicine, 344(5), 333-340.

Journal - Research Article

Manning, P. J., Allum, A., Jones, S., Sutherland, W. H. F., & Williams, S. M. (2001). The effect of hormone replacement therapy on cardiovascular risk factors in type 2 diabetes: A randomised controlled trial. Archives of Internal Medicine, 161, 1772-1776.

Journal - Research Article

Sutherland, W. H., Manning, P. J., de Jong, S. A., Allum, A. R., Jones, S. D., & Williams, S. M. (2001). Hormone replacement therapy increases serum paraoxonase arylesterase activity in diabetic postmenopausal women. Metabolism, 50, 319-324.

Journal - Research Article

Goulding, A., Jones, I. E., Taylor, R. W., Manning, P. J., & Williams, S. M. (2000). More broken bones: A 4-year double cohort study of young girls with and without distal forearm fractures. Journal of Bone & Mineral Research, 15(10), 2011-2018.

Journal - Research Article

Goulding, A., Taylor, R. W., Jones, I. E., McAuley, K. A., Manning, P. J., & Williams, S. M. (2000). Overweight and obese children have low bone mass and area for their weight. International Journal of Obesity, 24, 627-632.

Journal - Research Article

McAuley, K., Cambridge, L., Galloway, S. M., Sullivan, J. A., & Manning, P. J. (2000). De nono deletion of xq associated with premature ovarian failure. Australian & New Zealand Journal of Medicine, 30, 89-90.

Journal - Research Article

McBain, L., McLeod, D., Coppell, K., & Manning, P. (2000). The provision of care for patients with diabetes in general practice. New Zealand Family Physician, 27(26), 49-55.

Journal - Research Article

McBain, L., McLeod, D., Coppell, K., & Manning, P. J. (2000). Diabetes care in general practice. New Zealand Family Physician, 27(6), 49-60.

Journal - Research Article

Rodby, R. A., Rohde, R. D., Clarke, W. R., Hunsicker, L. G., Anzalone, D. A., Atkins, R. C., … Manning, P. J. (2000). The Ibesarten type 2 diabetic nephropathy trial: Study design and baseline characteristics. Nephrology Dialysis Transplantation, 15(4), 487-497.

Journal - Research Article

Schwartz, M. M., Lewis, E. J., Leonard-Martin, T., Lewis, J. B., Batlle, D., & Manning, P. J. (1998). Renal pathology patterns in type 2 diabetes mellitis: Relationship with retinopathy: The collaborative study group. Nephrology Dialysis Transplantation, 13(10), 2547-2552.

Journal - Research Article

Manning, P. J., Sutherland, W. H. F., & Mann, J. (1997). Hyperchylomicronaemia might have resolved anyway. British Medical Journal, 314, 65.

Journal - Research Article

Manning, P. J., Sutherland, W. H. F., & Mann, J. (1997). Late diagnosis of diabetic ketoacidosis and underlying disease influence response to treatment. British Medical Journal, 314, 63.

Journal - Research Article

McAuley, K. A., Jones, S., Lewis-Barned, N. J., Manning, P. J., & Goulding, A. (1997). Low vitamin D status is common among elderly Dunedin women. New Zealand Medical Journal, 110(1048), 275-277.

Journal - Research Article

Taylor, R. W., Gold, E. J., Manning, P. J., & Goulding, A. (1997). Gender differences in body fat content are present well before puberty. International Journal of Obesity, 21(11), 1082-1084.

Journal - Research Article

Florkowski, C. M., Holdaway, I. M., Manning, P. J., & Donald, R. A. (1996). The case for growth hormone replacement in adult hypopituitarism. New Zealand Medical Journal, 109, 349-351.

Journal - Research Article

Bellae Papannarao, J., Schwenke, D. O., Manning, P., & Katare, R. (2021). Upregulated miR-200c is associated with downregulation of the functional receptor for severe acute respiratory syndrome coronavirus 2 ACE2 in individuals with obesity [Brief communication]. International Journal of Obesity. Advance online publication. doi: 10.1038/s41366-021-00984-2

Journal - Research Other

Oliphant, J., Veale, J., Macdonald, J., Carroll, R., Johnson, R., Harte, M., … Cole, D., & Manning, P. (2018). Guidelines for gender affirming healthcare for gender diverse and transgender children, young people and adults in Aotearoa, New Zealand. New Zealand Medical Journal, 131(1487), 86-96. Retrieved from https://www.nzma.org.nz/journal

Journal - Research Other

De Ridder, D., Leong, S. L., Manning, P., Vanneste, S., & Glue, P. (2017). Anterior cingulate implant for obsessive-compulsive disorder. World Neurosurgery, 97, 754.e7-754.e16. doi: 10.1016/j.wneu.2016.10.046

Journal - Research Other

Manning, P. (2017). Osteoporosis and osteonecrosis of the jaw. New Zealand Dental Journal, 113(2), 2-3. [Editorial].

Journal - Research Other

De Ridder, D., Manning, P., Glue, P., Cape, G., Langguth, B., & Vanneste, S. (2016). Anterior cingulate implant for alcohol dependence. Neurosurgery, 78(6), E883-E893. doi: 10.1227/neu.0000000000001248

Journal - Research Other

Manning, T. E., Manning, A. E., & Manning, P. J. (2015). Systemic capillary leak syndrome: A case-report. New Zealand Medical Journal, 128(1415). Retrieved from https://www.nzma.org.nz/journal

Journal - Research Other

Baldi, J. C., Manning, P. J., Hofman, P. L., & Walker, R. J. (2013). Comment on: TODAY Study Group. Effects of Metformin, Metformin plus Rosiglitazone, and Metformin plus lifestyle on insulin sensitivity and β-cell function in TODAY. Diabetes Care 2013;36:1749-1757 [Comment]. Diabetes Care, 36, e223. doi: 10.2337/dc13-1426

Journal - Research Other

Wheeler, B. J., Patterson, N., Love, D. R., Prosser, D., Tomlinson, P., Taylor, B. J., & Manning, P. (2013). Frequency and genetic spectrum of maturity-onset diabetes of the young (MODY) in southern New Zealand. Journal of Diabetes & Metabolic Disorders, 12, 46. doi: 10.1186/2251-6581-12-46

Journal - Research Other

Choi, A.-R. A., & Manning, P. (2009). Overshooting the mark: Subclinical hyperthyroidism secondary to excess thyroid hormone treatment may be more prevalent than we realise [Letter]. New Zealand Medical Journal, 122(1289). Retrieved from http://journal.nzma.org.nz/journal/122-1289/3473/content.pdf

Journal - Research Other

Astwood, D., Yoon, H.-S., & Manning, P. J. (2006). Hyperandrogenism in a patient with previous colorectal cancer [Letter to the editor]. Internal Medicine Journal, 36(11), 751-752.

Journal - Research Other

Manning, P. J., Sutherland, W. H. F., & Walker, R. J. (2005). Effect of high-dose vitamin E on insulin resistance and associated parameters in overweight subjects [Response to Vale]. Diabetes Care, 28(1), 230-231.

Journal - Research Other

Stott, V., Manning, P., & Hung, N. (2005). Idiopathic granulomatous hypophysitis [Case report]. New Zealand Medical Journal, 118(1211). Retrieved from http://journal.nzma.org.nz/journal/118-1211/1355/content.pdf

Journal - Research Other

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