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Research projects available at the Department of Pathology

Investigating the role of Δ133p53 isoforms in regulating IL-6 mediated AKT/ NFκB signalling in prostate cancer

Close date
Tuesday, 31 December 2024
Supervisors
Dr Sunali Mehta, Professor Antony Braithwaite
Levels
Honours, Master’s

Evaluation of novel multitargeted therapeutic possibilities in ovarian cancer

Supervisors
Dr Sunali Mehta, Dr Mak Sarwar
Levels
Honours, Master’s

Modelling a cancer-associated human checkpoint protein variation in animal cells

Close date
Sunday, 31 December 2023
Supervisor
Dr Nicholas Fleming
Level
Honours

The role of KRAS in the emergence of drug tolerance in lung cancer

Supervisors
Dr Glen Reid, Dr Cath Drummond
Levels
Postgraduate Diploma, Honours, Master’s

New nucleic acid-based drugs for cancer therapy

Supervisor
Dr Glen Reid
Levels
Master’s, Honours

Modelling a human checkpoint protein variation in animal cells

Close date
Sunday, 31 December 2023
Supervisor
Dr Nicholas Fleming
Levels
Honours, Master’s

Regulatory role of the oncoprotein YB-1 in microtentacle formation and metastasis

Supervisor
Dr Adele Woolley
Levels
PhD, Honours, Master’s

Oocyte quality and fertility

Supervisor
Dr Karen Reader
Level
PhD

Understanding drug tolerance. How do tumours survive targeted therapy?

Supervisors
Dr Cath Drummond, Dr Glen Reid
Levels
Postgraduate Diploma, Honours, Master’s

Comprehensive characterization of uncommon TP53 mutations in cancer

Supervisor
Dr Sunali Mehta
Levels
Honours, Master’s


From remission to relapse: How do tumour resistance is driven under the pressure of immune responses?

Supervisors
Dr Kunyu Li, Professor Antony Braithwaite
Levels
Postgraduate Diploma, Honours, Master’s

Determine the contribution of the p53 isoform, Δ133p53, in the development of bowel inflammation and IBD

Supervisors
Dr Kunyu Li, Professor Antony Braithwaite
Levels
Postgraduate Diploma, Honours, Master’s


Characterisation of YB-1 interactions with the cytoskeleton using live cell imaging

Supervisor
Dr Adele Woolley
Levels
Honours, Master’s, PhD


Investigation of a Wnt/cohesin cause for AML

Supervisors
Professor Julia Horsfield, Dr Jisha Antony
Levels
Honours, Master’s, PhD

Reversal of enhancer dysregulation to combat cohesin-mutant leukemia

Supervisors
Dr Jisha Antony, Professor Julia Horsfield
Levels
Honours, Master’s, PhD


Molecular mechanisms of developmental disorders

Supervisor
Associate Professor Louise Bicknell
Level
PhD

Analysis of cancer genome atlas data to identify epigenetic signature of tumour metastasis

Supervisors
Associate Professor Aniruddha Chatterjee,
Levels
Postgraduate Certificate, Postgraduate Diploma, Honours, Master’s, PhD

Investigation of genetic and epigenetic signatures of primary and metastatic cancer (melanoma and colorectal cancer)

Supervisors
Associate Professor Aniruddha Chatterjee, Dr Euan Rodger
Levels
Postgraduate Certificate, Postgraduate Diploma, Honours, Master’s, PhD