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Understanding drug tolerance. How do tumours survive targeted therapy?

A postgraduate research opportunity at the University of Otago.

Details

Academic background
Health Sciences
Host campus
Dunedin
Qualifications
Postgraduate Diploma, Honours, Master’s
Department
Pathology (Dunedin)
Supervisors
Dr Cath Drummond, Dr Glen Reid

Overview

Cancer treatment has been revolutionised by therapies which act by specifically blocking the pathways that drive cancer.

However, despite initial dramatic results, relapse is inevitable and a major clinical problem.

Recent studies have identified a rare population of drug-tolerant cells as being largely responsible for relapse. These cells evade therapy by changing their identity during the course of treatment, thus surviving to repopulate the tumour.

This project involves using cellular and molecular biology to understand how drug-tolerant cells evade therapy to survive treatment.

Contact

Cath Drummond
Email   cath.drummond@otago.ac.nz