Much of the research in the Department of Pathology falls under the umbrella of cancer research. Cancer is a cell growth disease, whereby cells undergo cell division many more times than normal. Because of this they are prone to replication errors - mistakes that occur during the copying of the DNA on the chromosomes that occurs in each cell division. If these mistakes or mutations are not repaired they accumulate. As more and more mutations accumulate they affect cell processes involving death, location, intercellular communication and others. Eventually these “rogue” cells become cancers.
The Department of Pathology has a number of laboratories that work on different aspects of cancer biology. You can learn more about these below.
Laboratories involved in Cancer Biology:
- Braithwaite Laboratory: Cell Transformation
- Chatterjee Laboratory: Epigenetics, Disease and Phenotype
- Cunliffe Laboratory: Molecular Oncology
- Eccles Laboratory: Developmental Genetics and Pathology
- Hibma Laboratory: Viral Pathogenesis
- Horsfield Laboratory: Chromosome Structure & Development
- Hung & Slatter Laboratory: Molecular Pathology
- Morison Laboratory: Epigentics and Cancer
- Young Laboratory: Immunotherapy