Fran Munro
| Position | Research Assistant |
|---|---|
| Department | Department of Surgical Sciences (DSM) |
| Qualifications | BSc |
| Research summary | Colorectal cancer, vitamin D, gene expression |
Research
Fran is a research assistant for Prof. John McCall and is part of The Colorectal Translational Research Group.
She is also currently working towards an MSc in biochemistry. Her project examines aspects of vitamin D gene expression in healthy and tumour tissue, working towards determining whether a correlation between vitamin D levels and colorectal cancer exists.
Publications
Norton, S. E., Ward-Hartstonge, K. A., McCall, J. L., Leman, J. K. H., Taylor, E. S., Munro, F., Black, M. A., … Kemp, R. A. (2019). High-dimensional mass cytometric analysis reveals an increase in effector regulatory T cells as a distinguishing feature of colorectal tumors. Journal of Immunology. Advance online publication. doi: 10.4049/jimmunol.1801368
Campbell, H., Fleming, N., Roth, I., Mehta, S., Wiles, A., Williams, G., … Munro, F., McNoe, L., Black, M., McCall, J., Slatter, T. L., … Braithwaite, A. W. (2018). Δ133p53 isoform promotes tumour invasion and metastasis via interleukin-6 activation of JAK-STAT and RhoA-ROCK signalling. Nature Communications, 9(1), 254. doi: 10.1038/s41467-017-02408-0
Taylor, E. S., McCall, J. L., Shen, S., Girardin, A., Munro, F. M., Black, M. A., Ward-Hartstonge, K. A., & Kemp, R. A. (2018). Prognostic roles for IL-2-producing and CD69+ T cell subsets in colorectal cancer patients. International Journal of Cancer. Advance online publication. doi: 10.1002/ijc.31598
Woodfield, J., Zacharias, M., Wilson, G., Munro, F., Thomas, K., Gray, A., & Baldi, J. (2018). Protocol, and practical challenges, for a randomised controlled trial comparing the impact of high intensity interval training against standard care before major abdominal surgery: Study protocol for a randomised controlled trial. Trials, 19(1), 331. doi: 10.1186/s13063-018-2701-9
McInnes, T., Zou, D., Rao, D. S., Munro, F. M., Phillips, V. L., McCall, J. L., Black, M. A., Reeve, A. E., & Guilford, P. J. (2017). Genome-wide methylation analysis identifies a core set of hypermethylated genes in CIMP-H colorectal cancer. BMC Cancer, 17, 228. doi: 10.1186/s12885-017-3226-4
Journal - Research Article
Norton, S. E., Ward-Hartstonge, K. A., McCall, J. L., Leman, J. K. H., Taylor, E. S., Munro, F., Black, M. A., … Kemp, R. A. (2019). High-dimensional mass cytometric analysis reveals an increase in effector regulatory T cells as a distinguishing feature of colorectal tumors. Journal of Immunology. Advance online publication. doi: 10.4049/jimmunol.1801368
Campbell, H., Fleming, N., Roth, I., Mehta, S., Wiles, A., Williams, G., … Munro, F., McNoe, L., Black, M., McCall, J., Slatter, T. L., … Braithwaite, A. W. (2018). Δ133p53 isoform promotes tumour invasion and metastasis via interleukin-6 activation of JAK-STAT and RhoA-ROCK signalling. Nature Communications, 9(1), 254. doi: 10.1038/s41467-017-02408-0
Taylor, E. S., McCall, J. L., Shen, S., Girardin, A., Munro, F. M., Black, M. A., Ward-Hartstonge, K. A., & Kemp, R. A. (2018). Prognostic roles for IL-2-producing and CD69+ T cell subsets in colorectal cancer patients. International Journal of Cancer. Advance online publication. doi: 10.1002/ijc.31598
McInnes, T., Zou, D., Rao, D. S., Munro, F. M., Phillips, V. L., McCall, J. L., Black, M. A., Reeve, A. E., & Guilford, P. J. (2017). Genome-wide methylation analysis identifies a core set of hypermethylated genes in CIMP-H colorectal cancer. BMC Cancer, 17, 228. doi: 10.1186/s12885-017-3226-4
Ward-Hartstonge, K. A., McCall, J. L., McCulloch, T. R., Kamps, A.-K., Girardin, A., Cretney, E., Munro, F. M., & Kemp, R. A. (2017). Inclusion of BLIMP-1+ effector regulatory T cells improves the Immunoscore in a cohort of New Zealand colorectal cancer patients: A pilot study. Cancer Immunology, Immunotherapy, 66(4), 515-522. doi: 10.1007/s00262-016-1951-1
Norton, S. E., Dunn, E. T. J., McCall, J. L., Munro, F., & Kemp, R. A. (2016). Gut macrophage phenotype is dependent on the tumor microenvironment in colorectal cancer. Clinical & Translational Immunology, 5(4), e76. doi: 10.1038/cti.2016.21
Taylor, E. S., McCall, J. L., Girardin, A., Munro, F. M., Black, M. A., & Kemp, R. A. (2016). Functional impairment of infiltrating T cells in human colorectal cancer. OncoImmunology, 5(11), e1234573. doi: 10.1080/2162402X.2016.1234573
Journal - Research Other
Woodfield, J., Zacharias, M., Wilson, G., Munro, F., Thomas, K., Gray, A., & Baldi, J. (2018). Protocol, and practical challenges, for a randomised controlled trial comparing the impact of high intensity interval training against standard care before major abdominal surgery: Study protocol for a randomised controlled trial. Trials, 19(1), 331. doi: 10.1186/s13063-018-2701-9
