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DSM staff profile

Vicky Phillips

PositionLaboratory Manager
DepartmentDepartment of Surgical Sciences (Dunedin)
QualificationsNZCS(Biology)
Research summaryWhole genome scanning, proteomics, immunohistochemistry, cell culture and functional assays.
Clinical

Consenting of patients and specimen collection for research projects.

Research

Vicky works with Greg Jones in the Vascular Research Group. The techniques used in the Vascular Research Group include whole genome scanning, proteomics, immunohistochemistry, cell culture and functional assays.

She is co-investigator on a current research project funded by HRC.

A team member of the Colorectal Translational Research Group, Vicky is competent in RTPCR, real-time PCR and SNP6 assay as part of a Genome Wide Association Study (GWAS), and most molecular biology techniques.

Publications

Jones, G. T., Bown, M. J., Gretarsdottir, S., Romaine, S. P. R., Helgadottir, A., Yu, G., … Jin, C., … Phillips, L. V., Williams, M. J. A., Topless, R., Merriman, T. R., … Lewis, D. R., … van Rij, A. M. (2013). A sequence variant associated with sortilin-1 (SORT1) on 1p13.3 is independently associated with abdominal aortic aneurysm. Human Molecular Genetics, 22(14), 2941-2947. doi: 10.1093/hmg/ddt141

Tarr, G. P., Williams, M. J. A., Wilkins, G. T., Chen, V. H. T., Phillips, L. V., van Rij, A. M., & Jones, G. T. (2013). Intra-individual changes of active matrix metalloproteinase-9 are associated with clinical in-stent restenosis of bare metal stents. Cardiology, 124(1), 28-35. doi: 10.1159/000345591

Girardin, A., McCall, J., Black, M. A., Edwards, F., Phillips, V., Taylor, E. S., Reeve, A. E., & Kemp, R. A. (2013). Inflammatory and regulatory T cells contribute to a unique immune microenvironment in tumor tissue of colorectal cancer patients. International Journal of Cancer, 132(8), 1842-1850. doi: 10.1002/ijc.27855

Chu, J. W., Jones, G. T., Tarr, G. P., Phillips, L. V., Wilkins, G. T., van Rij, A. M., & Williams, M. J. A. (2013). Plasma active matrix metalloproteinase 9 and indices of diastolic function in patients with preserved systolic function. International Journal of Cardiology, 167(4), 1242-1246. doi: 10.1016/j.ijcard.2012.03.147

Roberts, R. L., van Rij, A. M., Phillips, L. V., Young, S., McCormick, S. P. A., Merriman, T. R., & Jones, G. T. (2011). Interaction of the inflammasome genes CARD8 and NLRP3 in abdominal aortic aneurysms. Atherosclerosis, 218(1), 123-126. doi: 10.1016/j.atherosclerosis.2011.04.043

Journal - Research Article

Girardin, A., McCall, J., Black, M. A., Edwards, F., Phillips, V., Taylor, E. S., Reeve, A. E., & Kemp, R. A. (2013). Inflammatory and regulatory T cells contribute to a unique immune microenvironment in tumor tissue of colorectal cancer patients. International Journal of Cancer, 132(8), 1842-1850. doi: 10.1002/ijc.27855

Tarr, G. P., Williams, M. J. A., Wilkins, G. T., Chen, V. H. T., Phillips, L. V., van Rij, A. M., & Jones, G. T. (2013). Intra-individual changes of active matrix metalloproteinase-9 are associated with clinical in-stent restenosis of bare metal stents. Cardiology, 124(1), 28-35. doi: 10.1159/000345591

Chu, J. W., Jones, G. T., Tarr, G. P., Phillips, L. V., Wilkins, G. T., van Rij, A. M., & Williams, M. J. A. (2013). Plasma active matrix metalloproteinase 9 and indices of diastolic function in patients with preserved systolic function. International Journal of Cardiology, 167(4), 1242-1246. doi: 10.1016/j.ijcard.2012.03.147

Jones, G. T., Bown, M. J., Gretarsdottir, S., Romaine, S. P. R., Helgadottir, A., Yu, G., … Jin, C., … Phillips, L. V., Williams, M. J. A., Topless, R., Merriman, T. R., … Lewis, D. R., … van Rij, A. M. (2013). A sequence variant associated with sortilin-1 (SORT1) on 1p13.3 is independently associated with abdominal aortic aneurysm. Human Molecular Genetics, 22(14), 2941-2947. doi: 10.1093/hmg/ddt141

Kemp, R. A., Black, M. A., McCall, J., Yoon, H.-S., Phillips, V., Anjomshoaa, A., & Reeve, A. E. (2011). T cell subpopulations in lymph nodes may not be predictive of patient outcome in colorectal cancer. Journal of Experimental & Clinical Cancer Research, 30, 78. doi: 10.1186/1756-9966-30-78

Roberts, R. L., van Rij, A. M., Phillips, L. V., Young, S., McCormick, S. P. A., Merriman, T. R., & Jones, G. T. (2011). Interaction of the inflammasome genes CARD8 and NLRP3 in abdominal aortic aneurysms. Atherosclerosis, 218(1), 123-126. doi: 10.1016/j.atherosclerosis.2011.04.043

Tarr, G. P., Williams, M. J. A., Phillips, L. V., van Rij, A. M., & Jones, G. T. (2011). Seasonal variation and stability of matrix metalloproteinase-9 activity and tissue inhibitor of matrix metalloproteinase-1 with storage at -80 oC. Clinical Biochemistry, 44(16), 1346-1348. doi: 10.1016/j.clinbiochem.2011.08.1139

Tarr, G. P., Williams, M. J. A., Phillips, L. V., van Rij, A. M., & Jones, G. T. (2011). Pro-MMP-9/TIMP-1 ratio correlates poorly with a direct assessment of MMP-9 activity. Clinical Biochemistry, 44(17-18), 1480-1482. doi: 10.1016/j.clinbiochem.2011.09.019

Nasri, S., Anjomshoaa, A., Song, S., Guilford, P., McNoe, L., Black, M., Phillips, V., Reeve, A., & Humar, B. (2010). Oligonucleotide array outperforms SNP array on formalin-fixed paraffin-embedded clinical samples. Cancer Genetics & Cytogenetics, 198(1), 1-6. doi: 10.1016/j.cancergencyto.2009.12.002

Jones, G. T., Tarr, G. P., Phillips, L. V., Wilkins, G. T., van Rij, A. M., & Williams, M. J. A. (2009). Active matrix metalloproteinases 3 and 9 are independently associated with coronary artery in-stent restenosis. Atherosclerosis, 207(2), 603-607. doi: 10.1016/j.atherosclerosis.2009.05.036

Jones, G. T., Kay, I. P., Chu, J. W. S., Wilkins, G. T., Phillips, L. V., McCormick, M., van Rij, A. M., & Williams, M. J. A. (2006). Elevated plasma active matrix metalloproteinase-9 level is associated with coronary artery in-stent restenosis. Arteriosclerosis, Thrombosis, & Vascular Biology, 26, e121-e125.

Jones, G. T., Harris, E. L., Phillips, L. V., & van Rij, A. M. (2005). The methylenetetrahydrofolate reductase C677T polymorphism does not associate with susceptibility to abdominal aortic aneurysm. European Journal of Vascular & Endovascular Surgery, 30(2), 137-142. doi: 10.1016/j.ejvs.2005.02.047

Merrie, A. E. M., van Rij, A. M., Dennett, E., Phillips, L. V., Yun, K., & McCall, J. L. (2003). Prognostic significance of occult metastases in colon cancer. Diseases of the Colon & Rectum, 46(2), 221-231.

Jones, G. T., Phillips, L. V., Harris, E. L., Rossaak, J. I., & van Rij, A. M. (2003). Functional matrix metalloproteinase-9 polymorphism (C-1562T) associated with abdominal aortic aneurysm. Journal of Vascular Surgery, 38, 1363-1367.

Merrie, A. E. H., Phillips, L. V., Yun, K., & McCall, J. L. (2001). Skip metastases in colon cancer: Assessment by lymph node mapping using molecular detection. Surgery, 129(6), 684-691. doi: 10.1067/msy.2001.113887

Rossaak, J. I., Hill, T. M., Jones, G. T., Phillips, L. V., Harris, E. L., & van Rij, A. M. (2001). Familial abdominal aortic aneurysms in the Otago region of New Zealand. Cardiovascular Surgery, 9, 241-248.

Merrie, A. E., van Rij, A. M., Phillips, L. V., Rossaak, J. I., Yun, K., & McCall, J. L. (2001). Diagnostic use of the sentinel node in colon cancer. Diseases of the Colon & Rectum, 44(3), 410-417.

Yun, K., Merrie, A. E. H., Phillips, L. V., & McCall, J. L. (2000). Keratin 20 is a specific marker of submicroscopic lymph node metastases in colorectal cancer: Validatiion by K-RAS mutations. Journal of Pathology, 191, 21-26.

Sutherland, W. H. F., Walker, R. J., de Jong, S. A., van Rij, A. M., Phillips, L. V., & Walker, H. (1999). Reduced postprandial serum paraoxonase activity after a meal rich in used cooking fat. Arteriosclerosis, Thrombosis, & Vascular Biology, 19, 1340-1347.

Merrie, A. E. H., Yun, K., Phillips, L. V., & McCall, J. L. (1999). Analysis of potential markers for detection of submicroscopic lymph node metastases in breast cancer. British Journal of Cancer, 80, 2019-2024.

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Journal - Research Other

Chu, J. W., Jones, G. T., Tarr, G. P., Phillips, L. V., Wilkins, G. T., van Rij, A. M., & Williams, M. J. A. (2011). Plasma active matrix metalloproteinase 9 associated to diastolic dysfunction in patients with coronary artery disease [Letter]. International Journal of Cardiology, 147(2), 336-338. doi: 10.1016/j.ijcard.2010.12.093

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