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DSM staff profile

Professor John Crump

PositionCo-Director, Otago Global Health Institute
DepartmentDepartment of Preventive and Social Medicine (DSM)
QualificationsMB ChB MD DTM&H FRACP FRCPA FRCP
Research summaryInfectious diseases in low-resource settings
Teaching
  • Global health
  • Global health ethics
Memberships
  • Fellow, Australasian College of Tropical Medicine
  • Fellow, Royal Society of Tropical Medicine and Hygiene
  • Fellow, American Society of Tropical Medicine and Hygiene
  • Fellow, Infectious Diseases Society of America
  • Member, American Society of Microbiology
Clinical
  • Infectious diseases
  • Medical microbiology

Research

My research is on the epidemiology, diagnosis, prevention, and management of major infectious causes of illness and death in low- and middle-income countries. I serve as the McKinlay Professor of Global Health and Co-Director of the Otago Global Health Institute, one of 12 flagship research centres of the University of Otago.

I graduated MB ChB and MD from the University of Otago in 1993 and 2011, respectively, and trained in both infectious diseases (FRACP, FRCP, DTM&H) and medical microbiology (FRCPA) in New Zealand, the United Kingdom, South Africa, Australia, and the United States.

My specific research interest is in the syndrome of fever and its management in low-resource areas, especially invasive bacterial diseases including the invasive salmonelloses. I lead efforts on global burden of disease estimates for both typhoidal and non-typhoidal Salmonella with related work on diarrhoeal diseases.

With partners in Myanmar and Tanzania, I lead research on causes of fever, febrile deaths, and infectious disease at that are major causes of both human febrile illness and production loss in animals. My work on these infections includes disease burden estimation, evaluation of new diagnostics, clinical management studies, risk factor research aimed at prevention interventions, and economic assessments. Goals of my work are to improve the health of individuals and populations in low- and middle-income countries through research and training in collaboration with local partners.

Publications

Snavely, M. E., Maze, M. J., Muiruri, C., Ngowi, L., Mboya, F., Beamesderfer, J., … Crump, J. A., … Rubach, M. P. (2018). Sociocultural and health system factors associated with mortality among febrile inpatients in Tanzania: A prospective social biopsy cohort study. BMJ Global Health, 3(1), e000507. doi: 10.1136/bmjgh-2017-000507

Parisi, A., Crump, J. A., Glass, K., Howden, B. P., Furuya-Kanamori, L., Vilkins, S., … Kirk, M. D. (2018). Health outcomes from multidrug-resistant Salmonella infections in high-income countries: A systematic review and meta-analysis. Foodborne Pathogens & Disease. Advance online publication. doi: 10.1089/fpd.2017.2403

Shrestha, P., Roberts, T., Homsana, A., Myat, T. O., Crump, J. A., Lubell, Y., & Newton, P. N. (2018). Febrile illness in Asia: Gaps in epidemiology, diagnosis, management for informing health policy. Clinical Microbiology & Infection. Advance online publication. doi: 10.1016/j.cmi.2018.03.028

Maze, M. J., Bassat, Q., Feasey, N. A., Mandomando, I., Musicha, P., & Crump, J. A. (2018). The epidemiology of febrile illness in sub-Saharan Africa: implications for diagnosis and management. Clinical Microbiology & Infection. Advance online publication. doi: 10.1016/j.cmi.2018.02.011

Crump, J. A., & Wain, J. (2017). Salmonella. In S. R. Quah & W. Cockerham (Eds.), International encyclopedia of public health (Vol. 6). (2nd ed.) (pp. 425-433). Elsevier. doi: 10.1016/B978-0-12-803678-5.00394-5

Chapter in Book - Research

Crump, J. A., & Wain, J. (2017). Salmonella. In S. R. Quah & W. Cockerham (Eds.), International encyclopedia of public health (Vol. 6). (2nd ed.) (pp. 425-433). Elsevier. doi: 10.1016/B978-0-12-803678-5.00394-5

DeCamp, M., Crump, J. A., Sugarman, J., Todd, T., & Walker, X. (2017). Existing and emerging ethical standards in global health education. In A. N. Arya & J. Evert (Eds.), Global health experiential education: From theory to practice. (pp. 114-131). Abingdon, UK: Routledge.

Crump, J. A., Newton, P. N., Baird, S. J., & Lubell, Y. (2017). Febrile illness in adolescents and adults. In K. K. Holmes, S. Bertozzi, B. R. Bloom & P. Jha (Eds.), Disease control priorities: Major infectious diseases (Vol. 6). (3rd ed.) (pp. 365-384). Washington, DC: World Bank. doi: 10.1596/978-1-4648-0524-0_ch14

Crump, J. A. (2016). Salmonella infections (including enteric fever). In L. Goldman & A. I. Schafer (Eds.), Goldman-Cecil medicine. (25th ed.) Philadelphia, PA: Elsevier Saunders.

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Journal - Research Article

Snavely, M. E., Maze, M. J., Muiruri, C., Ngowi, L., Mboya, F., Beamesderfer, J., … Crump, J. A., … Rubach, M. P. (2018). Sociocultural and health system factors associated with mortality among febrile inpatients in Tanzania: A prospective social biopsy cohort study. BMJ Global Health, 3(1), e000507. doi: 10.1136/bmjgh-2017-000507

Shrestha, P., Roberts, T., Homsana, A., Myat, T. O., Crump, J. A., Lubell, Y., & Newton, P. N. (2018). Febrile illness in Asia: Gaps in epidemiology, diagnosis, management for informing health policy. Clinical Microbiology & Infection. Advance online publication. doi: 10.1016/j.cmi.2018.03.028

Parisi, A., Crump, J. A., Glass, K., Howden, B. P., Furuya-Kanamori, L., Vilkins, S., … Kirk, M. D. (2018). Health outcomes from multidrug-resistant Salmonella infections in high-income countries: A systematic review and meta-analysis. Foodborne Pathogens & Disease. Advance online publication. doi: 10.1089/fpd.2017.2403

Cash-Goldwasser, S., Maze, M. J., Rubach, M. P., Biggs, H. M., Stoddard, R. A., Sharples, K. J., … Crump, J. A. (2017). Risk factors for human brucellosis in Northern Tanzania. American Journal of Tropical Medicine & Hygiene. Advance online publication. doi: 10.4269/ajtmh.17-0125

GBD 2016 DALYs and HALE Collaborators, including Crump, J. A., & Poulton, R. G. (2017). Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2016: A systematic analysis for the Global Burden of Disease Study 2016. Lancet, 390(10100), 1260-1344. doi: 10.1016/S0140-6736(17)32130-X

GBD 2016 Disease and Injury Incidence and Prevalence Collaborators, including Crump, J. A., & Poulton, R. G. (2017). Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990-2016: A systematic analysis for the Global Burden of Disease Study 2016. Lancet, 390(10100), 1211-1259. doi: 10.1016/S0140-6736(17)32154-2

GBD 2016 Mortality Collaborators, including Crump, J. A., & Poulton, R. G. (2017). Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970-2016: A systematic analysis for the Global Burden of Disease Study 2016. Lancet, 390(10100), 1084-1150. doi: 10.1016/S0140-6736(17)31833-0

Moore, C. C., Hazard, R., Saulters, K. J., Ainsworth, J., Adakun, S. A., Amir, A., … Crump, J. A., … Barnes, L. E. (2017). Derivation and validation of a universal vital assessment (UVA) score: A tool for predicting mortality in adult hospitalised patients in sub-Saharan Africa. BMJ Global Health, 2(2), e000344. doi: 10.1136/bmjgh-2017-000344

GBD 2016 Risk Factors Collaborators, including Crump, J. A., & Poulton, R. G. (2017). Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2016: A systematic analysis for the Global Burden of Disease Study 2016. Lancet, 390(10100), 1345-1422. doi: 10.1016/S0140-6736(17)32366-8

Myat, T. O., Hannaway, R. F., Zin, K. N., Htike, W. W., Win, K. K., Crump, J. A., Murdoch, D. R., & Ussher, J. E. (2017). ESBL- and carbapenemase-producing Enterobacteriaceae in patients with bacteremia, Yangon, Myanmar, 2014. Emerging Infectious Diseases, 23(5), 857-859. doi: 10.3201/eid2305.161100

Marks, F., von Kalckreuth, V., Aaby, P., Adu-Sarkodie, Y., El Tayeb, M. A., Ali, M., … Crump, J. A., … Wierzba, T. F. (2017). Incidence of invasive salmonella disease in sub-Saharan Africa: A multicentre population-based surveillance study. Lancet Global Health, 5(3), e310-e323. doi: 10.1016/s2214-109x(17)30022-0

The Global Burden of Disease Child and Adolescent Health Collaboration, including Crump, J. (2017). Child and adolescent health from 1990 to 2015: Findings from the global burden of diseases, injuries, and risk factors 2015 study. JAMA Pediatrics. Advance online publication. doi: 10.1001/jamapediatrics.2017.0250

Cleaveland, S., Sharp, J., Abela-Ridder, B., Allan, K. J., Buza, J., Crump, J. A., … Halliday, J. E. B. (2017). One Health contributions towards more effective and equitable approaches to health in low- and middle-income countries. Philosophical Transactions of the Royal Society B, 372(1725), 20160168. doi: 10.1098/rstb.2016.0168

GBD 2015 Healthcare Access and Quality Collaborators, including Crump, J. A. (2017). Healthcare Access and Quality Index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015: A novel analysis from the Global Burden of Disease Study 2015. Lancet, 390(10091), 231-266. doi: 10.1016/s0140-6736(17)30818-8

Bonell, A., Lubell, Y., Newton, P. N., Crump, J. A., & Paris, D. H. (2017). Estimating the burden of scrub typhus: A systematic review. PLoS Neglected Tropical Diseases, 11(9), e0005838. doi: 10.1371/journal.pntd.0005838

GBD 2016 SDG Collaborators, including Bhala, N., & Crump, J. A. (2017). Measuring progress and projecting attainment on the basis of past trends of the health-related Sustainable Development Goals in 188 countries: An analysis from the Global Burden of Disease Study 2016. Lancet, 390(10100), 1423-1459. doi: 10.1016/S0140-6736(17)32336-X

Al-Emran, H. M., Krumkamp, R., Dekker, D. M., Eibach, D., Aaby, P., Adu-Sarkodie, Y., … Crump, J. A., … Marks, F. (2016). Validation and identification of invasive Salmonella serotypes in Sub-Saharan Africa by multiplex polymerase chain reaction. Clinical Infectious Diseases, 62(Suppl. 1), S80-S82. doi: 10.1093/cid/civ782

Pavllinac, P. B., Lokken, E. M., Watson, J. L., Richardson, B. A., Crump, J. A., & John-Stewart, G. C. (2016). Mycobacterium tuberculosis bacteremia in adults and children: A systematic review and meta-analysis. International Journal of Tuberculosis & Lung Disease, 20(7), 895-902. doi: 10.5588/ijtld.15.0773

Aung, H. L., Tun, T., Moradigaravand, D., Köser, C. U., Nyunt, W. W., Aung, S. T., … Crump, J. A., … Cook, G. M., & Hill, P. C. (2016). Whole-genome sequencing of multidrug-resistant Mycobacterium tuberculosis isolates from Myanmar. Journal of Global Antimicrobial Resistance, 6, 113-117. doi: 10.1016/j.jgar.2016.04.008

Al-Emran, H. M., Eibach, D., Krumkamp, R., Ali, M., Baker, S., Biggs, H. M., … Crump, J. A., … Marks, F. (2016). A multicountry molecular analysis of Salmonella enterica serovar typhi with reduced susceptibility to ciprofloxacin in Sub-Saharan Africa. Clinical Infectious Diseases, 62(Suppl. 1), S42-S46. doi: 10.1093/cid/civ788

Zhang, H. L., Omondi, M. W., Musyoka, A. M., Afwamba, I. A., Swai, R. P., Karia, F. P., … Crump, J. A., & Rubach, M. P. (2016). Challenges of maintaining good clinical laboratory practices in low-resource settings: A health program evaluation framework case study from East Africa. American Journal of Clinical Pathology, 146(2), 199-206. doi: 10.1093/ajcp/aqw083

Aung, H. L., Tun, T., Permina, E., Nyunt, W. W., Aung, S. T., Thinn, K. K., Crump, J. A., & Cook, G. M. (2016). Draft genome sequences of two drug-resistant Mycobacterium tuberculosis isolates from Myanmar. Genome Announcements, 4(5), e00850-16. doi: 10.1128/genomeA.00850-16

Sowerby, S. J., Crump, J. A., Johnstone, M. C., Krause, K. L., & Hill, P. C. (2016). Smartphone microscopy of parasite eggs accumulated into a single field of view. American Journal of Tropical Medicine & Hygiene, 94(1), 227-230. doi: 10.4269/ajtmh.15-0427

Hart, P. J., O'Shaughnessy, C. M., Siggins, M. K., Bobat, S., Kingsley, R. A., Goulding, D. A., Crump, J. A., … MacLennan, C. A. (2016). Differential killing of Salmonella enterica serovar Typhi by antibodies targeting Vi and Lipopolysaccharide O:9 antigen. PLoS ONE, 11(1), e0145945. doi: 10.1371/journal.pone.0145945

Wong, V. K., Baker, S., Connor, T. R., Pickard, D., Page, A. J., Dave, J., … International Typhoid Consortium, including Crump, J. A. (2016). An extended genotyping framework for Salmonella enterica serovar Typhi, the cause of human typhoid. Nature Communications, 7, 12827. doi: 10.1038/ncomms12827

International Typhoid Consortium, Wong, V. K., Holt, K. E., Okoro, C., Baker, S., Pickard, D. J., … and also Crump, J. A. (2016). Molecular surveillance identifies multiple transmissions of typhoid in West Africa. PLoS Neglected Tropical Diseases, 10(9), e0004781. doi: 10.1371/journal.pntd.0004781

Maze, M. J., Biggs, H. M., Rubach, M. P., Galloway, R. L., Cash-Goldwasser, S., Allan, K. J., … Crump, J. A. (2016). Comparison of the estimated incidence of acute leptospirosis in the Kilimanjaro region of Tanzania between 2007-08 and 2012-14. PLoS Neglected Tropical Diseases, 10(12), e0005165. doi: 10.1371/journal.pntd.0005165

Liu, J., Ochieng, C., Wiersma, S., Ströher, U., Towner, J. S., Whitmer, S., … Crump, J. A., … Fields, B. (2016). Development of a TaqMan Array Card for acute febrile illness outbreak investigation and surveillance of emerging pathogens, including Ebola virus. Journal of Clinical Microbiology, 54(1), 49-58. doi: 10.1128/jcm.02257-15

Hertz, J. T., Lyaruu, L. J., Ooi, E. E., Mosha, F. W., & Crump, J. A. (2016). Distribution of Aedes mosquitoes in the Kilimanjaro Region of northern Tanzania. Pathogens & Global Health, 110(3), 108-112. doi: 10.1080/20477724.2016.1182719

Global Burden of Disease Pediatrics Collaboration, including Crump, J. A. (2016). Global and national burden of diseases and injuries among children and adolescents between 1990 and 2013: Findings from the Global Burden of Disease 2013 Study. JAMA Pediatrics, 170(3), 267-287. doi: 10.1001/jamapediatrics.2015.4276

Panzner, U., Pak, G. D., Aaby, P., Adu-Sarkodie, Y., Ali, M., Aseffa, A., … Crump, J. A., … Marks, F. (2016). Utilization of healthcare in the Typhoid Fever Surveillance in Africa Program. Clinical Infectious Diseases, 62(Suppl. 1), S56-S68. doi: 10.1093/cid/civ891

Park, S. E., Pak, G. D., Aaby, P., Adu-Sarkodie, Y., Ali, M., Aseffa, A., … Crump, J. A., … Marks, F. (2016). The relationship between invasive nontyphoidal Salmonella disease, other bacterial bloodstream infections, and malaria in Sub-Saharan Africa. Clinical Infectious Diseases, 62(Suppl. 1), S23-S31. doi: 10.1093/cid/civ893

Zhang, H. L., Mnzava, K. W., Mitchell, S. T., Melubo, M. L., Kibona, T. J., Cleaveland, S., … Crump, J. A., … Halliday, J. E. B. (2016). Mixed methods survey of zoonotic disease awareness and practice among animal and human healthcare providers in Moshi, Tanzania. PLoS Neglected Tropical Diseases, 10(3), e0004476. doi: 10.1371/journal.pntd.0004476

Halliday, J. E. B., Allan, K. J., Ekwem, D., Cleaveland, S., Kazwala, R. R., & Crump, J. A. (2015). Endemic zoonoses in the tropics: A public health problem hiding in plain sight. Veterinary Record, 176(9), 220-225. doi: 10.1136/vr.h798

Kumarasamy, N., Aga, E., Ribaudo, H. J., Wallis, C. L., Katzenstein, D. A., Stevens, W. S., … Crump, J. A., … Bartlett, J. A. (2015). Lopinavir/ritonavir monotherapy as second-line antiretroviral treatment in resource-limited settings: Week 104 analysis of AIDS Clinical Trial Group (ACTG) A5230. Clinical Infectious Diseases, 60(10), 1552-1558. doi: 10.1093/cid/civ109

Crump, J. A., Wu, X., Kendall, M. A., Ive, P. D., Kumwenda, J. J., Grinsztejn, B., … Swindells, S. (2015). Predictors and outcomes of Mycobacterium tuberculosis bacterium among patients with HIV and tuberculosis co-infection enrolled in the ACTG A5221 STRIDE study. BMC Infectious Diseases, 15, 12. doi: 10.1186/s12879-014-0735-5

GBD 2013 Mortality and Causes of Death Collaborators, including Crump, J. A., & Poulton, R. G. (2015). Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: A systematic analysis for the Global Burden of Disease Study 2013. Lancet, 385(9963), 117-171. doi: 10.1016/S0140-6736(14)61682-2

Sjölund-Karlsson, M., Howie, R., Rickert, R., Newton, A., Gonzalez-Aviles, G., & Crump, J. A. (2015). Plasmid-mediated quinolone resistance in isolates of Salmonella enterica serotype Typhi, USA. International Journal of Antimicrobial Agents, 45(1), 88-90. doi: 10.1016/j.ijantimicag.2014.09.015

Mavura, D. R., Masenga, E. J., Minja, E., Grossmann, H., Crump, J. A., & Bartlett, J. A. (2015). Initiation of antiretroviral therapy in HIV-infected adults with skin complaints in northern Tanzania. International Journal of Dermatology, 54(1), 68-73. doi: 10.1111/ijd.12563

Crump, J. A., Sjölund-Karlsson, M., Gordon, M. A., & Parry, C. M. (2015). Epidemiology, clinical presentation, laboratory diagnosis, antimicrobial resistance, and antimicrobial management of invasive Salmonella infections. Clinical Microbiology Reviews, 28(4), 901-937. doi: 10.1128/cmr.00002-15

Rubach, M. P., Maro, V. P., Bartlett, J. A., & Crump, J. A. (2015). Etiologies of illness among patients meeting Integrated Management of Adolescent and Adult Illness District Clinician Manual criteria for severe infections in Northern Tanzania: Implications for empiric antimicrobial therapy. American Journal of Tropical Medicine & Hygiene, 92(2), 454-462. doi: 10.4269/ajtmh.14-0496

Prasad, N., Sharples, K. J., Murdoch, D. R., & Crump, J. A. (2015). Community prevalence of fever and relationship with malaria among infants and children in low-resource areas. American Journal of Tropical Medicine & Hygiene, 93(1), 178-180. doi: 10.4269/ajtmh.14-0646

Ao, T. T., Feasey, N. A., Gordon, M. A., Keddy, K. H., Angulo, F. J., & Crump, J. A. (2015). Global burden of invasive nontyphoidal Salmonella Disease, 2010. Emerging Infectious Diseases, 21(6), 941-949. doi: 10.3201/eid2106.140999

Prasad, N., Murdoch, D. R., Reyburn, H., & Crump, J. A. (2015). Etiology of severe febrile illness in low- and middle-income countries: A systematic review. PLoS ONE, 10(6), e0127962. doi: 10.1371/journal.pone.0127962

Penno, E. C., Baird, S. J., & Crump, J. A. (2015). Cost-effectiveness of surveillance for bloodstream infections for sepsis management in low-resource settings. American Journal of Tropical Medicine & Hygiene, 93(4), 850-860. doi: 10.4269/ajtmh.15-0083

Penno, E. C., Crump, J. A., & Baird, S. J. (2015). Performance requirements to achieve cost-effectiveness of point-of-care tests for sepsis among patients with febrile illness in low-resource settings. American Journal of Tropical Medicine & Hygiene, 93(4), 841-849. doi: 10.4269/ajtmh.15-0082

Buchanan, A. M., Fiorillo, S. P., Omondi, M. W., Cunningham, C. K., & Crump, J. A. (2015). Establishment of biochemistry reference values for healthy Tanzanian infants, children, and adolescents in Kilimanjaro Region. Tropical Medicine & International Health, 20(11), 1569-1577. doi: 10.1111/tmi.12580

Global Burden of Disease Study 2013 Collaborators, including Bhala, N., Crump, J. A., Poulton, R. G., & Derrett, S. (2015). Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990-2013: A systematic analysis for the Global Burden of Disease Study 2013. Lancet, 386(9995), 743-800. doi: 10.1016/S0140-6736(15)60692-4

Allan, K. J., Biggs, H. M., Halliday, J. E. B., Kazwala, R. R., Maro, V. P., Cleaveland, S., & Crump, J. A. (2015). Epidemiology of leptospirosis in Africa: A systematic review of a neglected zoonosis and a paradigm for 'One Health' in Africa. PLoS Neglected Tropical Diseases, 9(9), e0003899. doi: 10.1371/journal.pntd.0003899

Nichols, C., Cruz Espinoza, L. M., von Kalckreuth, V., Aaby, P., El Tayeb, M. A., Ali, M., … Crump, J. A., … Marks, F. (2015). Bloodstream infections and frequency of pretreatment associated with age and hospitalization status in sub-Saharan Africa. Clinical Infectious Diseases, 61(Suppl. 4), S372-S379. doi: 10.1093/cid/civ730

Beardsley, J., Denning, D. W., Chau, N. V., Yen, N. T. B., Crump, J. A., & Day, J. N. (2015). Estimating the burden of fungal disease in Vietnam. Mycoses, 58(Suppl. 5), 101-106. doi: 10.1111/myc.12382

Wong, V. K., Baker, S., Pickard, D. J., Parkhill, J., Page, A. J., Feasey, N. A., … Crump, J. A., … Dougan, G. (2015). Phylogeographical analysis of the dominant multidrug-resistant H58 clade of Salmonella Typhi identifies inter- and intracontinental transmission events. Nature Genetics, 47(6), 632-639. doi: 10.1038/ng.3281

Kirk, M. D., Pires, S. M., Black, R. E., Caipo, M., Crump, J. A., Deveesschauwer, B., … Angulo, F. J. (2015). World Health Organization estimates of the global and regional disease burden of 22 foodborne bacterial, protozoal, and viral diseases, 2010: A data synthesis. PLoS Medicine, 12(12), e1001921. doi: 10.1371/journal.pmed.1001921

GBD 2013 DALYs, and HALE Collaborators, including Bhala, N., Crump, J. A., Derrett, S., & Poulton, R. G. (2015). Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthly life expectancy (HALE) for 188 countries, 1990-2013: Quantifying the epidemiological transition. Lancet, 386(10009), 2145-2191. doi: 10.1016/S0140-6736(15)61340-X

Vanderburg, S., Rubach, M. P., Halliday, J. E. B., Cleaveland, S., Reddy, E. A., & Crump, J. A. (2014). Epidemiology of Coxiella burnetii Infection in Africa: A OneHealth systematic review. PLoS Neglected Tropical Diseases, 8(4), e2787. doi: 10.1371/journal.pntd.0002787

Biggs, H. M., Lester, R., Nadjm, B., Mtove, G., Todd, J. E., Kinabo, G. D., … Crump, J. A. (2014). Invasive Salmonella infections in areas of high and low malaria transmission intensity in Tanzania. Clinical Infectious Diseases, 58(5), 638-647. doi: 10.1093/cid/cit798

Moon, A. M., Biggs, H. M., Rubach, M. P., Crump, J. A., Maro, V. P., Saganda, W., & Reddy, E. A. (2014). Evaluation of in-hospital management for febrile illness in Northern Tanzania before and after 2010 World Health Organization Guidelines for the Treatment of Malaria. PLoS ONE, 9(2), e89814. doi: 10.1371/journal.pone.0089814

Naccache, S. N., Federman, S., Veeraraghavan, N., Zaharia, M., Lee, D., Samayoa, E., … Crump, J. A., … Chiu, C. Y. (2014). A cloud-compatible bioinformatics pipeline for ultrarapid pathogen identification from next-generation sequencing of clinical samples. Genome Research, 24, 1180-1192. doi: 10.1101/gr.171934.113

Sjölund-Karlsson, M., Howie, R. L., Crump, J. A., & Whichard, J. M. (2014). Fluoroquinolone susceptibility testing of Salmonella enterica: Detection of acquired resistance and selection of zone diameter breakpoints for levofloxacin and ofloxacin. Journal of Clinical Microbiology, 52(3), 877-884. doi: 10.1128/jcm.02679-13

Reddy, E. A., Njau, B. N., Morpeth, S. C., Lancaster, K. E., Tribble, A. C., Maro, V. P., … Crump, J. A., … Hamilton, C. D. (2014). A randomized controlled trial of standard versus intensified tuberculosis diagnostics on treatment decisions by physicians in Northern Tanzania. BMC Infectious Diseases, 14, 89. doi: 10.1186/1471-2334-14-89

Myat, T. O., Prasad, N., Thinn, K. K., Win, K. K., Htike, W. W., Zin, K. N., Murdoch, D. R., & Crump, J. A. (2014). Bloodstream infections at a tertiary referral hospital in Yangon, Myanmar. Transactions of the Royal Society of Tropical Medicine and Hygiene, 108(11), 692-698. doi: 10.1093/trstmh/tru151

Crump, J. A., & Heyderman, R. S. (2014). Invasive Salmonella infections in Africa. Transactions of the Royal Society of Tropical Medicine and Hygiene, 108(11), 673-675. doi: 10.1093/trstmh/tru152

Thompson, C. N., Kama, M., Acharya, S., Bera, U., Clemens, J., Crump, J. A., … Mulholland, K. (2014). Typhoid fever in Fiji: A reversible plague? Tropical Medicine & International Health, 19(10), 1284-1292. doi: 10.1111/tmi.12367

Gray, K. D., Cunningham, C. K., Clifton, D. C., Afwamba, I. A., Mushi, G. S., Msuya, L. J., Crump, J. A., & Buchanan, A. M. (2013). Prevalence of mycobacteremia among HIV-infected infants and children in northern Tanzania. Pediatric Infectious Disease Journal, 32(7), 754-756. doi: 10.1097/INF.0b013e318286957f

Hertz, J. T., Munishi, O. M., Sharp, J. P., Reddy, E. A., & Crump, J. A. (2013). Comparing actual and perceived causes of fever among community members in a low malaria transmission setting in northern Tanzania. Tropical Medicine & International Health, 18(11), 1406-1415. doi: 10.1111/tmi.12191

Fiorillo, S. P., Diefenthal, H. C., Goodman, P. C., Ramadhani, H. O., Njau, B. N., Morrissey, A. B., … Crump, J. A. (2013). Chest radiography for predicting the cause of febrile illness among inpatients in Moshi, Tanzania. Clinical Radiology, 68(10), 1039-1046. doi: 10.1016/j.crad.2013.05.002

Crump, J. A., Morrissey, A. B., Nicholson, W. L., Massung, R. F., Stoddard, R. A., Galloway, R. L., … Bartlett, J. A. (2013). Etiology of severe non-malaria febrile illness in Northern Tanzania: A prospective cohort study. PLoS Neglected Tropical Diseases, 7(7), e2324. doi: 10.1371/journal.pntd.0002324

Biggs, H. M., Hertz, J. T., Munishi, O. M., Galloway, R. L., Marks, F., Saganda, W., … Crump, J. A. (2013). Estimating leptospirosis incidence using hospital-based surveillance and a population-based health care utilization survey in Tanzania. PLoS Neglected Tropical Diseases, 7(12), e2589. doi: 10.1371/journal.pntd.0002589

Biggs, H. M., Galloway, R. L., Bui, D. M., Morrissey, A. B., Maro, V. P., & Crump, J. A. (2013). Leptospirosis and human immunodeficiency virus co-infection among febrile inpatients in northern Tanzania. Vector-Borne & Zoonotic Diseases, 13(8), 572-580. doi: 10.1089/vbz.2012.1205

Rubach, M. P., Halliday, J. E. B., Cleaveland, S., & Crump, J. A. (2013). Brucellosis in low-income and middle-income countries. Current Opinion in Infectious Disease, 26, 404-412. doi: 10.1097/QCO.0b013e3283638104

Bartlett, J. A., Ribaudo, H. J., Wallis, C. L., Aga, E., Katzenstein, D. A., Stevens, W. S., … Crump, J. A., … Kumarasamy, N. (2012). Lopinavir/ritonavir monotherapy after virologic failure of first-line antiretroviral therapy in resource-limited settings. AIDS, 26(11), 1345-1353. doi: 10.1097/QAD.0b013e328353b066

Bonsignori, M., Montefiori, D. C., Wu, X., Chen, X., Hwang, K.-K., Tsao, C.-Y., … Crump, J. A., … Haynes, B. F. (2012). Two distinct broadly neutralizing antibody specificities of different clonal lineages in a single HIV-1-infected donor: Implications for vaccine design. Journal of Virology, 86(8), 4688-4692. doi: 10.1128/jvi.07163-11

Hertz, J. T., Munishi, O. M., Ooi, E. E., Howe, S., Lim, W. Y., Chow, A., … Crump, J. A. (2012). Chikungunya and Dengue fever among hospitalized febrile patients in Northern Tanzania. American Journal of Tropical Medicine & Hygiene, 86(1), 171-177. doi: 10.4269/ajtmh.2012.11-0393

Freel, S. A., Picking, R. A., Ferrari, G., Ding, H., Ochsenbauer, C., Kappes, J. C., … Crump, J. A., … Tomaras, G. D. (2012). Initial HIV-1 antigen-specific CD8+ T cells in acute HIV-1 infection inhibit transmitted/founder virus replication. Journal of Virology, 86(12), 6835-6846. doi: 10.1128/jvi.00437-12

Jennings, C., Harty, B., Granger, S., Wager, C., Crump, J. A., Fiscus, S. A., & Bremer, J. W. (2012). Cross-platform analysis of HIV-1 RNA data generated by a multicenter assay validation study with wide geographic representation. Journal of Clinical Microbiology, 50(8), 2737-2747. doi: 10.1128/jcm.00578-12

Crump, J. A., Ramadhani, H. O., Morrissey, A. B., Saganda, W., Mwako, M. S., Yang, L.-Y., … Bartlett, J. A. (2012). Bacteremic disseminated tuberculosis in sub-Saharan Africa: A prospective cohort study. Clinical Infectious Diseases, 55(2), 242-250. doi: 10.1093/cid/cis409

Clifton, D. C., Ramadhani, H. O., Msuya, L. J., Njau, B. N., Kinabo, G. D., Buchanan, A. M., & Crump, J. A. (2012). Predicting mortality for paediatric inpatients where malaria is uncommon. Archives of Disease in Childhood, 97(10), 889-894. doi: 10.1136/archdischild-2012-301812

Buchanan, A. M., Nadjm, B., Amos, B., Mtove, G., Sifuna, D., Cunningham, C. K., Crump, J. A., & Reyburn, H. (2012). Utility of rapid antibody tests to exclude HIV-1 infection among infants and children aged <18 months in a low-resource setting. Journal of Clinical Virology, 55(3), 244-249. doi: 10.1016/j.jcv.2012.08.001

Bouley, A. J., Biggs, H. M., Stoddard, R. A., Morrissey, A. B., Bartlett, J. A., Afwamba, I. A., … Crump, J. A. (2012). Brucellosis among hospitalized febrile patients in northern Tanzania. American Journal of Tropical Medicine & Hygiene, 87(6), 1105-1111. doi: 10.4269/ajtmh.2012.12-0327

Fiorillo, S. P., Landman, K. Z., Tribble, A. C., Mtalo, A., Itemba, D. K., Ostermann, J., … Crump, J. A. (2012). Changes in HIV risk behavior and seroincidence among clients presenting for repeat HIV counseling and testing in Moshi, Tanzania. AIDS Care, 24(10), 1264-1271. doi: 10.1080/09540121.2012.658751

Crump, J. A., Tuohy, M. J., Morrissey, A. B., Ramadhani, H. O., Njau, B. N., Maro, V. P., … Procop, G. W. (2012). Performance of nucleic acid amplification following extraction of 5 milliliters of whole blood for diagnosis of Mycobacterium tuberculosis bacteremia. Journal of Clinical Microbiology, 50(1), 138-141. doi: 10.1128/jcm.05963-11

Bonsignori, M., Hwang, K.-K., Chen, X., Tsao, C.-Y., Morris, L., Gray, E., … Crump, J. A., … Haynes, B. F. (2011). Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors. Journal of Virology, 85(19), 9998-10009. doi: 10.1128/jvi.05045-11

Biggs, H. M., Bui, D. M., Galloway, R. L., Stoddard, R. A., Shadomy, S. V., Morrissey, A. B., … Crump, J. A. (2011). Leptospirosis among hospitalized febrile patients in northern Tanzania. American Journal of Tropical Medicine & Hygiene, 85(2), 275-281. doi: 10.4269/ajtmh.2011.11-0176

Prabhu, M., Nicholson, W. L., Roche, A. J., Kersh, G. J., Fitzpatrick, K. A., Oliver, L. D., … Crump, J. A. (2011). Q fever, spotted fever group, and typhus group rickettsioses among hospitalized febrile patients in Northern Tanzania. Clinical Infectious Diseases, 53(4), e8-e15. doi: 10.1093/cid/cir411

Waters, R. C., Ostermann, J., Reeves, T. D., Masnick, M. F., Thielman, N. M., Bartlett, J. A., & Crump, J. A. (2011). A cost-effectiveness analysis of alternative HIV retesting strategies in sub-Saharan Africa. Journal of Acquired Immune Deficiency Syndromes, 56(5), 443-452. doi: 10.1097/QAI.0b013e3182118f8c

Crump, J. A., Ramadhani, H. O., Morrissey, A. B., Saganda, W., Mwako, M. S., Yang, L.-Y., … Maro, V. P. (2011). Invasive bacterial and fungal infections among hospitalized HIV-infected and HIV-uninfected adults and adolescents in northern Tanzania. Clinical Infectious Diseases, 52(3), 341-348. doi: 10.1093/cid/ciq103

Sjölund-Karlsson, M., Joyce, K., Blickenstaff, K., Ball, T., Haro, J., Medalla, F. M., … Crump, J. A., & Whichard, J. M. (2011). Antimicrobial susceptibility to azithromycin among Salmonella enterica isolates from the United States. Antimicrobial Agents & Chemotherapy, 55(9), 3985-3989. doi: 10.1128/aac.00590-11

Scott, L. E., Crump, J. A., Msuya, E., Morrissey, A. B., Venter, W. F., & Stevens, W. S. (2011). Abbott RealTime HIV-1 m2000rt viral load testing: Manual extraction versus the automated m2000sp extraction. Journal of Virological Methods, 172(1-2), 78-80. doi: 10.1016/j.jviromet.2010.12.006

Ostermann, J., Reddy, E. A., Shorter, M. M., Muiruri, C., Mtalo, A., Itemba, D. K., … Crump, J. A., & Thielman, N. M. (2011). Who tests, who doesn't, and why? Uptake of mobile HIV counseling and testing in the Kilimanjaro Region of Tanzania. PLoS ONE, 6(1), e16488. doi: 10.1371/journal.pone.0016488

McLellan, J. S., Pancera, M., Carrico, C., Gorman, J., Julien, J.-P., Khayat, R., … Crump, J. A., … Kwong, P. D. (2011). Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9. Nature, 480(7377), 336-343. doi: 10.1038/nature10696

Keddy, K. H., Sooka, A., Letsoalo, M. E., Hoyland, G., Chaignat, C. L., Morrissey, A. B., & Crump, J. A. (2011). Sensitivity and specificity of typhoid fever rapid antibody tests for laboratory diagnosis at two sub-Saharan African sites. Bulletin of the World Health Organization, 89(9), 640-647. doi: 10.2471/blt.11.087627

Crump, J. A., Ramadhani, H. O., Morrissey, A. B., Msuya, L. J., Yang, L.-Y., Chow, S.-C., … Kinabo, G. D. (2011). Invasive bacterial and fungal infections among hospitalized HIV-infected and HIV-uninfected children and infants in northern Tanzania. Tropical Medicine & International Health, 16(7), 830-837. doi: 10.1111/j.1365-3156.2011.02774.x

Crump, J. A., Morrissey, A. B., Ramadhani, H. O., Njau, B., Maro, V. P., & Reller, L. B. (2011). Controlled comparison of BacT/Alert MB system, manual Myco/F Lytic procedure, and Isolator 10 system for diagnosis of Mycobacterium tuberculosis bacteremia. Journal of Clinical Microbiology, 49(8), 3054-3057. doi: 10.1128/jcm.01035-11

Crump, J. A., Medalla, F. M., Joyce, K. W., Krueger, A. L., Hoekstra, R. M., Whichard, J. M., … and the Emerging Infections Program NARMS Working Groups. (2011). Antimicrobial resistance among invasive nontyphoidal Salmonella enterica isolates in the United States: National Antimicrobial Resistance Monitoring System, 1996 to 2007. Antimicrobial Agents & Chemotherapy, 55(3), 1148-1154. doi: 10.1128/aac.01333-10

Prabhu, M., Mchome, B., Ostermann, J., Itemba, D., Njau, B., Thielman, N., KIWAKKUKI-Duke VCT Study Group, including Crump, J. A. (2011). Prevalence and correlates of intimate partner violence among women attending HIV voluntary counseling and testing in northern Tanzania, 2005-2008. International Journal of Gynecology & Obstetrics, 113(1), 63-67. doi: 10.1016/j.ijgo.2010.10.019

Wu, X., Zhou, T., Zhu, J., Zhang, B., Georgiev, I., Wang, C., … Crump, J. A., … Mascola, J. R. (2011). Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing. Science, 333(6049), 1593-1602. doi: 10.1126/science.1207532

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