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DSM staff profile

Professor Alison Rich

PositionProfessor and Head of the Department of Pathology (Dunedin), and Head of the Oral Pathology Centre
DepartmentDepartment of Pathology (Dunedin)
QualificationsBDS(Otago) MDSc PhD(Melb) FRACDS FFOP(RCPA) FRCPath
Research summaryCurrent research interests are in the tumour microenvironment in oral cancer and immune regulation in oral lichen planus.
Clinical

Alison leads the Oral Pathology Centre, which provides specialist diagnostic oral pathology reports to dentists, dental specialists, and anatomical pathologists.

The Centre:

  • Analyses 2,500–3,000 specimens annually
  • Is fully equiped and certified for histopathology with accreditation in Medical Laboratory Testing (Histology) from International Accreditation New Zealand
  • Has Royal College of Pathologists of Australasia (RCPA), accreditation for teaching oral pathology

Research

Professor Rich's research interests relate to gaining a greater understanding of the pathogenesis of oral diseases, particularly oral cancer and oral lichen planus, to complement her clinical speciality of diagnostic oral pathology.

Her main research interest in oral cancer is in developing tools to more accurately predict the transformation of potentially malignant oral diseases to oral cancer and, investigation of the role of immune cells in the oral cancer environment. She has expertise in project design in these areas, in data analysis and in mentoring colleagues and post- and undergraduate students undertaking related projects. She has supervised numerous PhD and DClinDent students from around the world, with particular interest in supporting the development of diagnostic and research oral pathology in the Asia-Pacific region.

Professor Rich is the leader of the Oral Molecular and Immunopathology Programme of the Sir John Walsh Research Institute and has numerous international collaborative projects, especially with colleagues in Malaysia, Australia and Sri Lanka.

Additional details

Professor Rich is a previous Chair of the Faculty of Oral and Maxillofacial Pathology of the Royal College of Pathologists of Australasia (RCPA) and is their current Chief Examiner. She is an Associate Editor of Pathology, the journal of the RCPA. Her laboratory convenes the oral and maxillofacial Quality Assurance Programme for the RCPA.

Alison is a past Councillor for Australasia for the International Association of Oral Pathologists (IAOP) and has participated in numerous IAOP congresses over the years.

Publications

Berryman, Z., Bridger, L., Hussaini, H. M., Rich, A. M., Atieh, M., & Tawse-Smith, A. (2020). Titanium particles: An emerging risk factor for peri-implant bone loss. Saudi Dental Journal, 32, 283-292. doi: 10.1016/j.sdentj.2019.09.008

Guan, G., Mei, L., Polonowita, A., Hussaini, H., Seo, B., & Rich, A. M. (2020). Malignant transformation in oral lichen planus and lichenoid lesions: A 14-year longitudinal cohort study of 829 patients in New Zealand. Oral Surgery, Oral Medicine, Oral Pathology & Oral Radiology. Advance online publication. doi: 10.1016/j.oooo.2020.07.002

Yu, Z., Seo, B., Hussaini, H. M., Meldrum, A. M., & Rich, A. M. (2020). The relative frequency of paediatric oral and maxillofacial pathology in New Zealand: A 10-year review of a national specialist centre. International Journal of Paediatric Dentistry, 30, 209-215. doi: 10.1111/ipd.12590

Adam, L. A., Oranje, J., Rich, A. M., & Meldrum, A. (2020). Advancing dental education: Feedback processes in the clinical learning environment. Journal of the Royal Society of New Zealand, 50(1), 144-157. doi: 10.1080/03036758.2019.1656650

McElroy, K. E., Seo, B. L., Hussaini, H. M., & Rich, A. M. (2020). Graft versus host disease: Cases from New Zealand with oral manifestations. New Zealand Dental Journal, 116(2), 47-54.

Journal - Research Article

Berryman, Z., Bridger, L., Hussaini, H. M., Rich, A. M., Atieh, M., & Tawse-Smith, A. (2020). Titanium particles: An emerging risk factor for peri-implant bone loss. Saudi Dental Journal, 32, 283-292. doi: 10.1016/j.sdentj.2019.09.008

McElroy, K. E., Seo, B. L., Hussaini, H. M., & Rich, A. M. (2020). Graft versus host disease: Cases from New Zealand with oral manifestations. New Zealand Dental Journal, 116(2), 47-54.

Adam, L. A., Oranje, J., Rich, A. M., & Meldrum, A. (2020). Advancing dental education: Feedback processes in the clinical learning environment. Journal of the Royal Society of New Zealand, 50(1), 144-157. doi: 10.1080/03036758.2019.1656650

Yu, Z., Seo, B., Hussaini, H. M., Meldrum, A. M., & Rich, A. M. (2020). The relative frequency of paediatric oral and maxillofacial pathology in New Zealand: A 10-year review of a national specialist centre. International Journal of Paediatric Dentistry, 30, 209-215. doi: 10.1111/ipd.12590

Guan, G., Mei, L., Polonowita, A., Hussaini, H., Seo, B., & Rich, A. M. (2020). Malignant transformation in oral lichen planus and lichenoid lesions: A 14-year longitudinal cohort study of 829 patients in New Zealand. Oral Surgery, Oral Medicine, Oral Pathology & Oral Radiology. Advance online publication. doi: 10.1016/j.oooo.2020.07.002

Lu, E. M.-C., Ratnayake, J., & Rich, A. M. (2019). Assessment of proliferating cell nuclear antigen (PCNA) expression at the invading front of oral squamous cell carcinoma. BMC Oral Health, 19, 233. doi: 10.1186/s12903-019-0928-9

Al-Hassiny, A., Hussani, H., Milne, T., Seo, B., Rich, A. M., & Friedlander, L. T. (2019). Vascularity and angiogenic signaling in the dentine-pulp complex of immature and mature permanent teeth. European Endodontic Journal, 4(2), 80-85. doi: 10.14744/eej.2019.26349

Yakin, M., Seo, B., & Rich, A. (2019). Tunicamycin-induced endoplasmic reticulum stress up-regulates tumour-promoting cytokines in oral squamous cell carcinoma. Cytokine, 120, 130-143. doi: 10.1016/j.cyto.2019.04.013

Mohd Thiyahuddin, N., Lamping, E., Rich, A. M., & Cannon, R. D. (2019). Yeast species in the oral cavities of older people: A comparison between people living in their own homes and those in rest homes. Journal of Fungi, 5(2), 30. doi: 10.3390/jof5020030

Al-Hassiny, A., Friedlander, L. T., Parachuru, V. P. B., Seo, B., Hussaini, H. M., & Rich, A. M. (2018). Upregulation of angiogenesis in oral lichen planus. Journal of Oral Pathology & Medicine, 47(2), 173-178. doi: 10.1111/jop.12665

Parachuru, V. P. B., Coates, D. E., Milne, T. J., Rich, A. M., & Seymour, G. J. (2018). FoxP3+ regulatory T cells, interleukin 17 and mast cells in chronic inflammatory periodontal disease. Journal of Periodontal Research, 53(4), 622-635. doi: 10.1111/jre.12552

Ebbeling, S., Adam, L., Meldrum, A., Rich, A., McLean, A., & Aitken, W. (2018). Oral health and dental students' perceptions of their clinical learning environment: A focus group study. Journal of Dental Education, 82(10), 1036-1042. doi: 10.21815/JDE.018.102

Friedlander, L. T., Coates, D., Seymour, G., Cullinan, M., & Rich, A. M. (2018). Vascularity and VEGF/VEGFR2 signaling in the dentine–pulp complex of immature and mature permanent teeth. European Endodontic Journal, 3(3), 153-159. doi: 10.14744/eej.2018.07269

Tawse-Smith, A., Ma, S., Duncan, W. J., Gray, A., Reid, M. R., & Rich, A. M. (2017). Implications of wear at the titanium-zirconia implant-abutment interface on the health of peri-implant tissues. International Journal of Oral & Maxillofacial Implants, 32(3), 599-609. doi: 10.11607/jomi.5014

Hussaini, H. M., Parachuru, V. P. B., Seymour, G. J., & Rich, A. M. (2017). Forkhead box-P3+ regulatory T cells and toll-like receptor 2 co-expression in oral squamous cell carcinoma. Acta Histochemica, 119(3), 205-210. doi: 10.1016/j.acthis.2016.12.005

Seo, B., Hussaini, H. M., & Rich, A. M. (2017). Second opinion oral pathology referrals in New Zealand. Pathology, 49(3), 277-284. doi: 10.1016/j.pathol.2016.11.007

Apperley, O., Medlicott, N., Rich, A., Hanning, S., & Huckabee, M. L. (2017). A clinical trial of a novel emulsion for potential use as a saliva substitute in patients with radiation induced xerostomia. Journal of Oral Rehabilitation, 44(11), 889-895. doi: 10.1111/joor.12545

Avadhani, A. V., Parachuru, V. P. B., Milne, T., Seymour, G. J., & Rich, A. M. (2017). Multiple cells express interleukin 17 in oral squamous cell carcinoma. Journal of Oral Pathology & Medicine, 46(1), 39-45. doi: 10.1111/jop.12465

Yakin, M., Gavidi, R. O., Cox, B., & Rich, A. (2017). Oral cancer risk factors in New Zealand. New Zealand Medical Journal, 130(1451), 30-38. Retrieved from https://www.nzma.org.nz/journal

Kazantseva, M., Hung, N. A., Mehta, S., Roth, I., Eiholzer, R., Rich, A. M., Seo, B., Baird, M. A., Braithwaite, A. W., & Slatter, T. L. (2017). Tumor protein 53 mutations are enriched in diffuse large B-cell lymphoma with irregular CD19 marker expression. Scientific Reports, 7, 1566. doi: 10.1038/s41598-017-01800-6

Sinon, S. H., Rich, A. M., Parachuru, V. P. B., Firth, F. A., Milne, T., & Seymour, G. J. (2016). Downregulation of toll-like receptor-mediated signalling pathways in oral lichen planus. Journal of Oral Pathology & Medicine, 45, 28-34. doi: 10.1111/jop.12319

Foster Page, L. A., Gray, L., Gallagher, P., McKinlay, E., & Rich, A. M. (2016). Untangling the web of influences on dental students' participation in interprofessional education programs. Journal of Dental Education, 80(6), 677-685.

Seo, B., Coates, D. E., Seymour, G. J., & Rich, A. M. (2016). Unfolded protein response-related gene regulation in inflamed periodontal tissues with and without Russell bodies. Archives of Oral Biology, 69, 1-6. doi: 10.1016/j.archoralbio.2016.04.009

Javvadi, L. R., Parachuru, V. P. B., Milne, T. J., Seymour, G. J., & Rich, A. M. (2016). Regulatory T-cells and IL17A+ cells infiltrate oral lichen planus lesions. Pathology, 48(6), 564-573. doi: 10.1016/j.pathol.2016.06.002

Yakin, M., Jalal, J. A., Al-Khurri, L. E., & Rich, A. M. (2016). Oral and maxillofacial pathology submitted to Rizgary Teaching Hospital: A 6-year retrospective study. International Dental Journal, 66(2), 78-85. doi: 10.1111/idj.12211

Firth, F. A., Friedlander, L. T., Parachuru, V. P. B., Kardos, T. B., Seymour, G. J., & Rich, A. M. (2015). Regulation of immune cells in oral lichen planus. Archives of Dermatological Research, 307, 333-339. doi: 10.1007/s00403-015-1540-8

Friedlander, L. T., Hussaini, H., Cullinan, M. P., Seymour, G. J., De Silva, R. K., De Silva, H., Cameron, C., & Rich, A. M. (2015). VEGF and VEGFR2 in dentigerous cysts associated with impacted third molars. Pathology, 47(5), 446-451. doi: 10.1097/pat.0000000000000272

Bakri, M. M., Rich, A. M., Cannon, R. D., & Holmes, A. R. (2015). In vitro expression of Candida albicans alcohol dehydrogenase genes involved in acetaldehyde metabolism. Molecular Oral Microbiology, 30(1), 27-38. doi: 10.1111/omi.12064

Anderson, V. R., Rapana, S. T., Broughton, J. R., Seymour, G. J., & Rich, A. M. (2015). Preliminary findings from the Oranga Niho dental student outplacement project. New Zealand Dental Journal, 111(1), 6-14.

Gavidi, R. O., Rich, A. M., Cox, B., & King, T. (2014). Comparing the occurrence of oral squamous cell carcinoma in New Zealand and the Fiji Islands from 2000-2010. International Journal of Cancer Research, 48(1), 1212-1225.

Rich, A. M., Hussaini, H. M., Parachuru, V. P. B., & Seymour, G. J. (2014). Toll-like receptors and cancer, particularly oral squamous cell carcinoma. Frontiers in Immunology, 5, 464. doi: 10.3389/fimmu.2014.00464

Bakri, M. M., Cannon, R. D., Holmes, A. R., & Rich, A. M. (2014). Detection of Candida albicans ADH1 and ADH2 mRNAs in human archival oral biopsy samples. Journal of Oral Pathology & Medicine, 43(9), 704-710. doi: 10.1111/jop.12193

Parachuru, V. P. B., Coates, D. E., Milne, T. J., Hussaini, H. M., Rich, A. M., & Seymour, G. J. (2014). Forkhead box P3-positive regulatory T-cells and interleukin 17-positive T-helper 17 cells in chronic inflammatory periodontal disease. Journal of Periodontal Research, 49(6), 817-826. doi: 10.1111/jre.12169

Hunter, K., Speight, P., Wright, J., van Heerden, W., Rich, A., & Franklin, C. (2014). An international survey of speciality training in oral and maxillofacial pathology. Journal of Oral Pathology & Medicine, 43(3), 232-236. doi: 10.1111/jop.12118

Kamel, M. S., Broadbent, J. M., & Rich, A. M. (2013). Epidemiological and clinical characteristics of oral leukoplakia in a New Zealand population: Analysis of a 10-year case series. Journal of Dental, Oral & Craniofacial Epidemiology, 1(4), 6-13.

Sinon, S. H., Rich, A. M., Firth, N. A., & Seymour, G. J. (2013). Qualitative and quantitative assessment of immune cells in oral mucosal lichen planus (OMLP). Sains Malaysiana, 42(1), 65-71.

Sinon, S. H., Rich, A. M., Hussaini, H. M., Yoon, H.-S., Firth, N. A., & Seymour, G. J. (2013). Metastases to the oral region from pleural mesothelioma: Clinicopathologic review. Head & Neck, 35(4), 599-604. doi: 10.1002/hed.21942

Rich, A. M., Ayers, K. M. S., Thomson, W. M., Sinclair, R. J., Rohan, M. J., & Seymour, G. J. (2012). Does performance in selection processes predict performance as a dental student? European Journal of Dental Education, 16(1), 27-34. doi: 10.1111/j.1600-0579.2011.00706.x

Hussaini, H. M., Angel, C. M., Speight, P. M., Firth, N. A., & Rich, A. M. (2012). A double-clear variant of epithelial-myoepithelial carcinoma of the parotid gland. Head & Neck Pathology, 6(4), 471-475. doi: 10.1007/s12105-012-0350-y

Anderson, V. R., Rich, A. M., & Seymour, G. J. (2011). Undergraduate dental education in New Zealand: 2007-2009 final-year student feedback on clinical learning environments. New Zealand Dental Journal, 107(3), 85-90.

Desai, S. V., Love, R. M., Rich, A. M., & Seymour, G. J. (2011). Toll-like receptor 2 expression in refractory periapical lesions. International Endodontic Journal, 44(10), 907-916. doi: 10.1111/j.1365-2591.2011.01893.x

Ng, L. K., Rich, A. M., Hussaini, H. M., Thomson, W. M., Fisher, A. L., Horne, L. S., & Seymour, G. J. (2011). Toll-like receptor 2 is present in the microenvironment of oral squamous cell carcinoma. British Journal of Cancer, 104(3), 460-463. doi: 10.1038/sj.bjc.6606057

Jattan, R., De Silva, H. L., De Silva, R. K., Rich, A. M., & Love, R. M. (2011). A case series of odontogenic keratocysts from a New Zealand population over a 20-year period. New Zealand Dental Journal, 107(4), 112-116.

Campbell, D. I., De Silva, R. K., De Silva, H., Sinon, S. H., & Rich, A. M. (2011). Temporomandibular joint synovial chondromatosis with intracranial extension: A review and observations of patient observed for 4 years. Journal of Oral & Maxillofacial Surgery, 69(8), 2247-2252. doi: 10.1016/j.joms.2010.10.042

Desai, S. V., Love, R. M., Rich, A. M., & Seymour, G. J. (2011). Antigen recognition and presentation in periapical tissues: A role for TLR expressing cells? International Endodontic Journal, 44(2), 87-99. doi: 10.1111/j.1365-2591.2010.01817.x

Hussaini, H. M., Waddell, J. N., Girvan, L., West, L. M., Kardos, T. B., Rich, A. M., & Seymour, G. J. (2011). Silver solder ″tattoo,″: A novel form of oral pigmentation identified with the use of field emission scanning electron microscopy and electron dispersive spectrography. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, & Endodontology, 112(4), e6-e10. doi: 10.1016/j.tripleo.2011.03.049

Rosdy, N. M. M. N. M., Firth, N. A., & Rich, A. M. (2010). Calibre-persistent labial artery: Often misdiagnosed as a mucocoele. International Journal of Oral & Maxillofacial Surgery, 39(12), 1230-1233. doi: 10.1016/j.ijom.2010.05.003

Mohd Bakri, M., Hussaini, H. M., Holmes, A. R., Cannon, R. D., & Rich, A. M. (2010). Revisiting the association between candidal infection and carcinoma, particularly oral squamous cell carcinoma. Journal of Oral Microbiology, 2, 5780. doi: 10.3402/jom.v2i0.5780

Ayers, K. M. S., Thomson, W. M., Newton, J. T., Morgaine, K. C., & Rich, A. M. (2009). Self-reported occupational health of general dental practitioners. Occupational Medicine, 59(3), 142-148. doi: 10.1093/occmed/kqp004

Kaur, J., Hay, K. D., Macdonald, H., & Rich, A. M. (2009). Retrospective audit of the use of the Marx Protocol for prophylactic hyperbaric oxygen therapy in managing patients requiring dental extractions following radiotherapy to the head and neck. New Zealand Dental Journal, 105(2), 47-50.

Ayers, K. M. S., Thomson, W. M., Rich, A. M., & Newton, J. T. (2008). Gender differences in dentists' working practices and job satisfaction. Journal of Dentistry, 36(5), 343-350. doi: 10.1016/j.jdent.2008.01.012

Ayers, K. M. S., Thomson, W. M., Newton, J. T., & Rich, A. M. (2008). Job stressors of New Zealand dentists and their coping strategies. Occupational Medicine, 58(4), 275-281. doi: 10.1093/occmed/kqn014

Ayers, K. M. S., Thomson, W. M., Whyman, R. A., Rich, A. M., & Newton, J. T. (2008). Changes in the New Zealand dentist workforce over a nine-year period. New Zealand Dental Journal, 104(1), 19-26.

Ayers, K. M. S., Thomson, W. M., Al-Hassiny, H., Rich, A. M., & Newton, J. T. (2008). A qualitative investigation of the experiences of immigrant dentists working in New Zealand. New Zealand Dental Journal, 104(3), 97-103.

Lou, S. M.-Y., Rich, A. M., De Silva, R. K., & Ferguson, M. M. (2006). Pleomorphic adenoma of a molar salivary gland. Oral Oncology EXTRA, 42, 170-172.

Innes, P., & Rich, A. (2005). Changes in the selection of dental students in New Zealand. New Zealand Dental Journal, 101(1), 19-21.

Beggs, K. T., Holmes, A. R., Cannon, R. D., & Rich, A. M. (2004). Detection of Candida albicans mRNA in archival histopathology samples by reverse transcription-PCR. Journal of Clinical Microbiology, 42(5), 2275-2278.

Rich, A. M., & Reade, P. C. (2001). Epithelial-mesenchymal interactions in experimental oral mucosal carcinogenesis. Journal of Oral Pathology & Medicine, 30, 389-397.

Rich, A. M. (2000). Tongue lesions: What can it be? Annals of the Royal Australasian College of Dental Surgeons, 15, 106-110.

Rich, A. M., Firth, N. A., & Reade, P. C. (1999). A colour atlas of gum diseases. Part 2: noninfectious causes. Modern Medicine, 42, 28-37.

Rich, A. M., Kerdpon, D., & Reade, P. C. (1999). P53 expression in oral precancer and cancer. Australian Dental Journal, 44, 103-105.

Polonowita, A. D., Firth, N. A., & Rich, A. M. (1999). Verruciform xanthoma and concomitant lichen planus of the oral mucosa. International Journal of Oral & Maxillofacial Surgery, 28, 62-66.

Rich, A. M., Firth, N. A., & Reade, P. C. (1999). A colour atlas of gum diseases: Part 1: Infectious and immunological causes. Modern Medicine, 42, 66-81.

Firth, N. A., Rich, A. M., & Reade, P. C. (1998). A colour atlas of diseases of the tongue. Modern Medicine, 41, 34-45.

Kerdpon, D., Rich, A. M., & Reade, P. C. (1997). Expression of p53 in oral mucosal hyperplasia, dysplasia and squamous cell carcinoma. Oral Diseases, 3, 86-92.

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Journal - Research Other

Rich, A. M., Hussaini, H. M., Seo, B., & Zain, R. B. (2020). Understanding the complex microenvironment in oral cancer: The contribution of the Faculty of Dentistry, University of Otago over the last 100 years. Journal of the Royal Society of New Zealand, 50(1), 15-34. doi: 10.1080/03036758.2020.1736586

Olson, H., Ronayne, C., Anakin, M., Meldrum, A., & Rich, A. (2020). Working together in clinical pathology: An interprofessional education initiative for dentistry, oral health, and medical laboratory science teachers and students. MedEdPublish. Advance online publication. doi: 10.15694/mep.2020.000009.1

Yakin, M., Seo, B., Hussaini, H., Rich, A., & Hunter, K. (2019). Human papillomavirus and oral and oropharyngeal carcinoma: The essentials. Australian Dental Journal, 64, 11-18. doi: 10.1111/adj.12652

Hussaini, H. M., Parachuru, V. P. B., Seymour, G. J., & Rich, A. M. (2017). FoxP3 and TLR2 in co-expression in oral cancer. Acta Histochemica, 119(7), 768. doi: 10.1016/j.acthis.2017.06.006

Rich, A. M., Seo, B., Parachuru, V., & Hussaini, H. M. (2017). The nexus between periodontics and oral pathology. Periodontology 2000, 74(1), 176-181. doi: 10.1111/prd.12197

Tawse-Smith, A., Atieh, M. A., Leichter, J., Girvan, L., & Rich, A. M. (2015). Peri-implant bone loss and its uncommon causes: A case report. Clinical Advances in Periodontics, 5(4), 242-247. doi: 10.1902/cap.2014.140024

Goldsmith, S. M., Seo, B. L., de Silva, R. K., Parachuru, P., Rich, A. M., & Seymour, G. J. (2014). Oral mycosis fungoides: Report with immune profile. Oral Surgery, Oral Medicine, Oral Pathology & Oral Radiology, 118(2), e48-e52. doi: 10.1016/j.oooo.2013.10.005

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