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Centre for Free Radical Research Publications


  • Mohammad A, Saini RV, Kumar R, Sharma D, Saini NK, Gupta A, Thakur P, Winterbourn CC, Saini AK. A curious case of cysteines in human peroxiredoxin I. Redox Biol. 2020 Oct;37:101738. doi: 10.1016/j.redox.2020.101738. Epub 2020 Sep 24. PMID: 33011678 Free PMC article.
  • Conner TS, Fletcher BD, Pullar JM, Spencer E, Mainvil LA, Vissers MCM. KiwiC for Vitality: Results of a Randomized Placebo-Controlled Trial Testing the Effects of Kiwifruit or Vitamin C Tablets on Vitality in Adults with Low Vitamin C Levels. Nutrients. 2020 Sep 22;12(9):2898. doi: 10.3390/nu12092898. PMID: 32971991 Free PMC article.
  • White R, Nonis M, Pearson JF, Burgess E, Morrin HR, Pullar JM, Spencer E, Vissers MCM, Robinson BA, Dachs GU. Low Vitamin C Status in Patients with Cancer Is Associated with Patient and Tumor Characteristics. Nutrients. 2020 Aug 5;12(8):2338. doi: 10.3390/nu12082338. PMID: 32764253 Free PMC article.
  • Ashby LV, Springer R, Hampton MB, Kettle AJ, Winterbourn CC. Evaluating the bactericidal action of hypochlorous acid in culture media. Free Radic Biol Med. 2020 Nov 1;159:119-124. doi: 10.1016/j.freeradbiomed.2020.07.033. Epub 2020 Jul 30. PMID: 32739594
  • Peskin AV, Meotti FC, de Souza LF, Anderson RF, Winterbourn CC, Salvador A. Intra-dimer cooperativity between the active site cysteines during the oxidation of peroxiredoxin 2. Free Radic Biol Med. 2020 Oct;158:115-125. doi: 10.1016/j.freeradbiomed.2020.07.007. Epub 2020 Jul 20. PMID: 32702382
  • Bathish B, Paumann-Page M, Paton LN, Kettle AJ, Winterbourn CC. Peroxidasin mediates bromination of tyrosine residues in the extracellular matrix. J Biol Chem. 2020 Sep 4;295(36):12697-12705. doi: 10.1074/jbc.RA120.014504. Epub 2020 Jul 16. PMID: 32675287
  • Dickerhof N, Paton L, Kettle AJ. Oxidation of bacillithiol by myeloperoxidase-derived oxidants. Free Radic Biol Med. 2020 Oct;158:74-83. doi: 10.1016/j.freeradbiomed.2020.06.009. Epub 2020 Jul 3. PMID: 32629107
  • van Leeuwen E, Hampton MB, Smyth LCD. Redox signalling and regulation of the blood-brain barrier. Int J Biochem Cell Biol. 2020 Aug;125:105794. doi: 10.1016/j.biocel.2020.105794. Epub 2020 Jun 17. PMID: 32562769 Review.
  • Sevcnikar B, Schaffner I, Chuang CY, Gamon L, Paumann-Page M, Hofbauer S, Davies MJ, Furtmüller PG, Obinger C. The leucine-rich repeat domain of human peroxidasin 1 promotes binding to laminin in basement membranes. Arch Biochem Biophys. 2020 Aug 15;689:108443. doi: 10.1016/ Epub 2020 May 30. PMID: 32485152
  • Winterbourn CC. Hydrogen peroxide reactivity and specificity in thiol-based cell signalling. Biochem Soc Trans. 2020 Jun 30;48(3):745-754. doi: 10.1042/BST20190049. PMID: 32412042
  • Pearson AG, Zawari M, Pearson JF, Hampton MB. Quantifying mitochondrial respiration in human lymphocytes and monocytes challenged with hydrogen peroxide. Free Radic Res. 2020 Apr;54(4):271-279. doi: 10.1080/10715762.2020.1753722. Epub 2020 Apr 24. PMID: 32326774
  • O'Connor KM, Das AB, Winterbourn CC, Hampton MB. Inhibition of DNA methylation in proliferating human lymphoma cells by immune cell oxidants. J Biol Chem. 2020 Jun 5;295(23):7839-7848. doi: 10.1074/jbc.RA120.013092. Epub 2020 Apr 20. PMID: 32312750
  • Dickerhof N, Huang J, Min E, Michaëlsson E, Lindstedt EL, Pearson JF, Kettle AJ, Day BJ. Myeloperoxidase inhibition decreases morbidity and oxidative stress in mice with cystic fibrosis-like lung inflammation. Free Radic Biol Med. 2020 May 20;152:91-99. doi: 10.1016/j.freeradbiomed.2020.03.001. Epub 2020 Mar 4. PMID: 32142878
  • Ahuie GK, Gagnon H, Pace PE, Peskin AV, Wagner RJ, Naylor S, Klarskov K. Investigating protein thiol chemistry associated with dehydroascorbate, homocysteine and glutathione using mass spectrometry. Rapid Commun Mass Spectrom. 2020 Jun 15;34(11):e8774. doi: 10.1002/rcm.8774. PMID: 32119756
  • Kader T, Porteous CM, Jones GT, Dickerhof N, Narayana VK, Tull D, Taraknath S, McCormick SPA. Ribose-cysteine protects against the development of atherosclerosis in apoE-deficient mice. PLoS One. 2020 Feb 21;15(2):e0228415. doi: 10.1371/journal.pone.0228415. eCollection 2020. PMID: 32084149 Free PMC article.
  • Pullar JM, Dunham S, Dachs GU, Vissers MCM, Carr AC. Erythrocyte Ascorbate Is a Potential Indicator of Steady-State Plasma Ascorbate Concentrations in Healthy Non-Fasting Individuals. Nutrients. 2020 Feb 6;12(2):418. doi: 10.3390/nu12020418. PMID: 32041092 Free PMC article.
  • Meng Y, Sheen CR, Magon NJ, Hampton MB, Dobson RCJ. Structure-function analyses of alkylhydroperoxidase D from Streptococcus pneumoniae reveal an unusual three-cysteine active site architecture. J Biol Chem. 2020 Mar 6;295(10):2984-2999. doi: 10.1074/jbc.RA119.012226. Epub 2020 Jan 23. PMID: 31974167
  • Sevcnikar B, Paumann-Page M, Hofbauer S, Pfanzagl V, Furtmüller PG, Obinger C. Reaction of human peroxidasin 1 compound I and compound II with one-electron donors. Arch Biochem Biophys. 2020 Mar 15;681:108267. doi: 10.1016/ Epub 2020 Jan 15. PMID: 31953133
  • Schneider M, Hannaway RF, Lamichhane R, de la Harpe SM, Tyndall JDA, Vernall AJ, Kettle AJ, Ussher JE. Neutrophils suppress mucosal-associated invariant T cells in humans. Eur J Immunol. 2020 May;50(5):643-655. doi: 10.1002/eji.201948394. Epub 2020 Feb 3. PMID: 31944287
  • Magon NJ, Parker HA, Ashby LV, Springer RJ, Hampton MB. Analysis of Neutrophil Bactericidal Activity. Methods Mol Biol. 2020;2087:149-164. doi: 10.1007/978-1-0716-0154-9_12. PMID: 31728990
  • Carr AC, Spencer E, Hoskin TS, Rosengrave P, Kettle AJ, Shaw G. Circulating myeloperoxidase is elevated in septic shock and is associated with systemic organ failure and mortality in critically ill patients. Free Radic Biol Med. 2020 May 20;152:462-468. doi: 10.1016/j.freeradbiomed.2019.11.004. Epub 2019 Nov 5. PMID: 31698081
  • Chami B, San Gabriel PT, Kum-Jew S, Wang X, Dickerhof N, Dennis JM, Witting PK. The nitroxide 4-methoxy-tempo inhibits the pathogenesis of dextran sodium sulfate-stimulated experimental colitis. Redox Biol. 2020 Jan;28:101333. doi: 10.1016/j.redox.2019.101333. Epub 2019 Sep 28. PMID: 31593888 Free PMC article.
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