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Dr Andrew Das

Andrew Das

Postdoctoral Fellow

MBChB, PhD (Otago)

Email andrew.das@otago.ac.nz 
Tel 64 3 364 0567

Research interests

Dr Andrew Das is investigating potential links between leukaemia and the roles of ascorbate in cell biochemistry.

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Publications

Vissers, M. C. M., & Das, A. B. (2018). Potential mechanisms of action for vitamin C in cancer: Reviewing the evidence. Frontiers in Physiology, 9, 809. doi: 10.3389/fphys.2018.00809

Das, A., Morison, I., Kennedy, M., & Vissers, M. (2017, October). The potential use of ascorbate as an epigenetic drug in acute myeloid leukaemia. Poster session presented at the New Zealand Society for Oncology (NZSO) Conference, Auckland, New Zealand.

Das, A. B., Sadowska-Bartosz, I., Königstorfer, A., Kettle, A. J., & Winterbourn, C. C. (2018). Superoxide dismutase protects ribonucleotide reductase from inactivation in yeast. Free Radical Biology & Medicine, 116, 114-122. doi: 10.1016/j.freeradbiomed.2018.01.001

Das, A. B., Nauser, T., Koppenol, W. H., Kettle, A. J., Winterbourn, C. C., & Nagy, P. (2014). Rapid reaction of superoxide with insulin-tyrosyl radicals to generate a hydroperoxide with subsequent glutathione addition. Free Radical Biology & Medicine, 70, 86-95. doi: 10.1016/j.freeradbiomed.2014.02.006

Das, A. B., Nagy, P., Abbott, H. F., Winterbourn, C. C., & Kettle, A. J. (2010). Reactions of superoxide with the myoglobin tyrosyl radical. Free Radical Biology & Medicine, 48, 1540-1547. doi: 10.1016/j.freeradbiomed.2010.02.039

Journal - Research Article

Das, A. B., Sadowska-Bartosz, I., Königstorfer, A., Kettle, A. J., & Winterbourn, C. C. (2018). Superoxide dismutase protects ribonucleotide reductase from inactivation in yeast. Free Radical Biology & Medicine, 116, 114-122. doi: 10.1016/j.freeradbiomed.2018.01.001

Das, A. B., Nauser, T., Koppenol, W. H., Kettle, A. J., Winterbourn, C. C., & Nagy, P. (2014). Rapid reaction of superoxide with insulin-tyrosyl radicals to generate a hydroperoxide with subsequent glutathione addition. Free Radical Biology & Medicine, 70, 86-95. doi: 10.1016/j.freeradbiomed.2014.02.006

Nagy, P., Lechte, T. P., Das, A. B., & Winterbourn, C. C. (2012). Conjugation of glutathione to oxidized tyrosine residues in peptides and proteins. Journal of Biological Chemistry, 287(31), 26068-26076. doi: 10.1074/jbc.M112.371690

Das, A. B., Nagy, P., Abbott, H. F., Winterbourn, C. C., & Kettle, A. J. (2010). Reactions of superoxide with the myoglobin tyrosyl radical. Free Radical Biology & Medicine, 48, 1540-1547. doi: 10.1016/j.freeradbiomed.2010.02.039

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Journal - Research Other

Vissers, M. C. M., & Das, A. B. (2018). Potential mechanisms of action for vitamin C in cancer: Reviewing the evidence. Frontiers in Physiology, 9, 809. doi: 10.3389/fphys.2018.00809

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Conference Contribution - Published proceedings: Abstract

Das, A., Nagy, P., Lecthe, T., Koppenol, W. H., Winterbourn, C. C., & Kettle, A. (2013). Detection of glutathione conjugated to oxidised tyrosine residues on proteins. Free Radical Biology & Medicine, 65(Suppl. 2), (pp. S55). doi: 10.1016/j.freeradbiomed.2013.10.520

Das, A. B., Nagy, P., Abbott, H., Winterbourn, C. C., & Kettle, A. J. (2009). Reactions of superoxide with the myoglobin tyrosyl radical. Free Radical Biology and Medicine. 47(Suppl. 1), (pp. S74). [Abstract]

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Conference Contribution - Poster Presentation (not in published proceedings)

Das, A., Morison, I., Kennedy, M., & Vissers, M. (2017, October). The potential use of ascorbate as an epigenetic drug in acute myeloid leukaemia. Poster session presented at the New Zealand Society for Oncology (NZSO) Conference, Auckland, New Zealand.

Das, A. B., Nagy, P., Lechte, T., Winterbourn, C. C., & Kettle, A. J. (2013, August). Detection of glutathione conjugated to oxidized tyrosine residues on protein. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

Das, A. B., Nagy, P., Abbott, H., Winterbourn, C. C., & Kettle, A. J. (2009, September). Superoxide mediated protein oxidation: A potential mechanism for superoxide toxicity. Poster session presented at the Third Annual Division of Health Sciences Research Forum, Wellington, New Zealand.

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Conference Contribution - Verbal presentation and other Conference outputs

Brown, C. M., Das, A., Stevens, S., Biswas, A., Gagnon, J., McKinney, C., Chen, A., & Chen, S. (2011, September). Bioinformatic approaches to discover post-transcriptional regulatory elements in human mRNAs. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

Das, A. (2008, November). Reactions of superoxide with the myoglobin tyrosol radical. Verbal presentation at the Society for Free Radical Research Australasia Conference, Melbourne, Australia.

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Awarded Doctoral Degree

Das, A. B. (2017). The reactions of superoxide with tyrosyl radicals on proteins (PhD). University of Otago, Dunedin, New Zealand. Retrieved from http://hdl.handle.net/10523/7065

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