The Gene Structure and Function Laboratory are interested in the application of genetics to the understanding and treatment of disease.
Our main research themes are pharmacogenomics, psychiatric genetics, and the genetics of complex disease.
We have a dual approach to questions of interest, on the one hand using laboratory-based experimentation with cell lines and other model systems, and on the other using DNA samples collected in clinical trials and other studies.
We can complement and extend findings from the laboratory based studies by genetic analysis in our study cohorts, thus providing an immediate test of predictions and hypotheses evolving in the laboratory.
Our laboratory is a key part of the Carney Centre for Pharmacogenomics.