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Contact Details

Phone
+64 3 479 7292
Email
rajesh.katare@otago.ac.nz
Position
Associate Professor and Head of Department
Department
Department of Physiology
Qualifications
MBBS PhD
Research summary
Cardiovascular disease; diabetes
Teaching
  • Teaching PHSL 232, ELM 2, PHSL 471, HUBS 192
  • Special topics: BIOE 404, BIOE 405
Memberships
  • Physiological Society of New Zealand
  • American Heart Association
  • Association of Physiologists of India
  • HeartOtago
  • Pain at Otago

Research

My research interests include:

  • Molecular mechanisms involved in the development of cardiovascular complications in diabetes
  • Role of microRNAs in cardiovascular diseases
  • Development of novel genetic therapies for the treatment of ischemic and non-ischemic cardiovascular complications

Projects include:

  • Pathological role of microRNAs in the development of diabetic cardiomyopathy
  • Circulating microRNAs as potential biomarkers for early diagnosis of cardiovascular complications
  • Investigating the role of suicidal autophagy in diabetic hearts
  • Mechanistic therapies for the treatment of diabetic ulcer
  • Nanoparticle mediated delivery of RNA for the treatment of cardiovascular disease

Publications

Caporali, A., Anwar, M., Devaux, Y., Katare, R., Martelli, F., Srivastava, P. K., … Emanueli, C. (2024). Non-coding RNAs as therapeutic targets and biomarkers in ischaemic heart disease [Review]. Nature Reviews Cardiology. Advance online publication. doi: 10.1038/s41569-024-01001-5

Mellor, K. M., Varma, U., Koutsifeli, P., Daniels, L. J., Benson, V. L., Annandale, M., … Katare, R., … Delbridge, L. M. D. (2024). Myocardial glycophagy flux dysregulation and glycogen accumulation characterize diabetic cardiomyopathy. Journal of Molecular & Cellular Cardiology, 189, 83-89. doi: 10.1016/j.yjmcc.2024.02.009

Sun, D., Katare, R., Sethu, P., Cheng, P., & Fan, Y. (2024). Constructing the vascular or cardiac tissue and organoids: The combination of biomedicine and engineering. Frontiers in Cardiovascular Medicine, 11, 1371074. doi: 10.3389/fcvm.2024.1371074

Avolio, E., Campagnolo, P., Katare, R., & Madeddu, P. (2024). The role of cardiac pericytes in health and disease: Therapeutic targets for myocardial infarction. Nature Reviews Cardiology, 21, 106-118. doi: 10.1038/s41569-023-00913-y

Reynolds, A. N., Hood, F., Wilson, R., Ross, A., Neumann, S., Turner, R., Iosua, E., Katare, R., Shahin, A., Kok, Z.-y., … Coffey, S., & Mann, J. (2023). Healthy grocery delivery in the usual care for adults recovering from an acute coronary event: protocol for a three-arm randomised controlled trial. BMJ Open, 13, e074278. doi: 10.1136/bmjopen-2023-074278

Dixit, P., & Katare, R. G. (2019). Isolation and characterization of cardiac progenitor cells. In M. V. Joglekar & A. A. Hardikar (Eds.), Progenitor cells: Methods and protocols: Methods in molecular biology (Vol. 2029). (pp. 161-173). New York, NY: Humana Press. doi: 10.1007/978-1-4939-9631-5_13

Chapter in Book - Research

Avolio, E., Campagnolo, P., Katare, R., & Madeddu, P. (2024). The role of cardiac pericytes in health and disease: Therapeutic targets for myocardial infarction. Nature Reviews Cardiology, 21, 106-118. doi: 10.1038/s41569-023-00913-y

Journal - Research Article

Caporali, A., Anwar, M., Devaux, Y., Katare, R., Martelli, F., Srivastava, P. K., … Emanueli, C. (2024). Non-coding RNAs as therapeutic targets and biomarkers in ischaemic heart disease [Review]. Nature Reviews Cardiology. Advance online publication. doi: 10.1038/s41569-024-01001-5

Journal - Research Article

Mellor, K. M., Varma, U., Koutsifeli, P., Daniels, L. J., Benson, V. L., Annandale, M., … Katare, R., … Delbridge, L. M. D. (2024). Myocardial glycophagy flux dysregulation and glycogen accumulation characterize diabetic cardiomyopathy. Journal of Molecular & Cellular Cardiology, 189, 83-89. doi: 10.1016/j.yjmcc.2024.02.009

Journal - Research Article

Chandrasekera, D., Shah, R., van Hout, I., de Jonge, W., Bunton, R., Parry, D., Davis, P., & Katare, R. (2023). Combination of precipitation and size exclusion chromatography as an effective method for exosome like extracellular vesicle isolation from pericardial fluids. Nanotheranostics, 7(4), 345-352. doi: 10.7150/ntno.82939

Journal - Research Article

Farrell, G., Reily-Bell, M., Chapple, C., Kennedy, E., Sampath, K., Gisselman, A. S., … Katare, R., & Tumilty, S. (2023). Autonomic nervous system and endocrine system response to upper and lower cervical spine mobilization in healthy male adults: A randomized crossover trial. Journal of Manual & Manipulative Therapy, 31(6), 421-434. doi: 10.1080/10669817.2023.2177071

Journal - Research Article

Khadka, P., Dummer, J., Hill, P. C., Katare, R., & Das, S. C. (2023). A review of formulations and preclinical studies of inhaled rifampicin for its clinical translation. Drug Delivery & Translational Research, 13, 1246-1271. doi: 10.1007/s13346-022-01238-y

Journal - Research Article

Munasinghe, P. E., Saw, E. L., Reily-Bell, M., Tonkin, D., Kakinuma, Y., Fronius, M., & Katare, R. (2023). Non-neuronal cholinergic system delays cardiac remodelling in type 1 diabetes. Heliyon, 9, e17434. doi: 10.1016/j.heliyon.2023.e17434

Journal - Research Article

Tonkin, D., Yee-Goh, A., & Katare, R. (2023). Healing the ischaemic heart: A critical review of stem cell therapies. Reviews in Cardiovascular Medicine, 24(4), 122. doi: 10.31083/j.rcm2404122

Journal - Research Article

Avolio, E., Katare, R., Thomas, A. C., Caporali, A., Schwenke, D., Carrabba, M., … Madeddu, P. (2022). Cardiac pericyte reprogramming by MEK inhibition promotes arteriologenesis and angiogenesis of the ischemic heart. Journal of Clinical Investigation, 132(10), e152308. doi: 10.1172/jci152308

Journal - Research Article

Ghosh, N., Fenton, S., van Hout, I., Jones, G. T., Coffey, S., Williams, M. J. A., Sugunesegran, R., Parry, D., … Schwenke, D. O., Chatterjee, A., & Katare, R. (2022). Therapeutic knockdown of miR-320 improves deteriorated cardiac function in a pre-clinical model of non-ischemic diabetic heart disease. Molecular Therapy: Nucleic Acids, 29, 330-342. doi: 10.1016/j.omtn.2022.07.007

Journal - Research Article

Satthenapalli, R., Lee, S., Bellae Papannarao, J., Hore, T. A., Chakraborty, A., Jones, P. P., Lamberts, R. R., & Katare, R. (2022). Stage-specific regulation of signalling pathways to differentiate pluripotent stem cells to cardiomyocytes with ventricular lineage. Stem Cell Research & Therapy, 13(1), 185. doi: 10.1186/s13287-022-02845-9

Journal - Research Article

Waddingham, M. T., Tsuchimochi, H., Sonobe, T., Asano, R., Jin, H., Ow, C. P. C., Schwenke, D. O., Katare, R., … Pearson, J. T. (2022). Using synchrotron radiation imaging techniques to elucidate the actions of hexarelin in the heart of small animal models. Frontiers in Physiology, 12, 766818. doi: 10.3389/fphys.2021.766818

Journal - Research Article

Yee-Goh, A. S., Yamauchi, A., van Hout, I., Bellae Papannarao, J., Sugunesegran, R., Parry, D., Davis, P., & Katare, R. (2022). Cardiac progenitor cells and adipocyte stem cells from same patients exhibit in vitro functional differences. International Journal of Molecular Sciences, 23, 5588. doi: 10.3390/ijms23105588

Journal - Research Article

Avolio, E., Mangialardi, G., Slater, S. C., Alvino, V. V., Gu, Y., Cathery, W., … Katare, R., … Madeddu, P. (2021). Secreted Protein Acidic and Cysteine Rich matricellular protein is enriched in the bioactive fraction of the human vascular pericyte secretome. Antioxidants & Redox Signaling, 34(15), 1151-1164. doi: 10.1089/ars.2019.7969

Journal - Research Article

Chamorro-Jorganes, A., Sweaad, W. K., Katare, R., Besnier, M., Anwar, M., Beazley-Long, N., … Chandrasekera, D., … Emanueli, C. (2021). METTL3 regulates angiogenesis by modulating let-7e-5p and miRNA-18a-5p expression in endothelial cells. Arteriosclerosis, Thrombosis, & Vascular Biology, 41, e325-e337. doi: 10.1161/atvbaha.121.316180

Journal - Research Article

Coffey, S., Dixit, P., Saw, E. L., Babakr, A. A., van Hout, I., Galvin, I. F., Saxena, P., Bunton, R. W., Davis, P. J., Lamberts, R. R., Katare, R., & Williams, M. J. A. (2021). Thiamine increases resident endoglin positive cardiac progenitor cells and atrial contractile force in humans: A randomised controlled trial. International Journal of Cardiology, 341, 70-73. doi: 10.1016/j.ijcard.2021.08.039

Journal - Research Article

Khadka, P., Sinha, S., Tucker, I. G., Dummer, J., Hill, P. C., Katare, R., & Das, S. C. (2021). Pharmacokinetics of rifampicin after repeated intra-tracheal administration of amorphous and crystalline powder formulations to Sprague Dawley rats. European Journal of Pharmaceutics & Biopharmaceutics, 162, 1-11. doi: 10.1016/j.ejpb.2021.02.011

Journal - Research Article

Khadka, P., Sinha, S., Tucker, I. G., Dummer, J., Hill, P. C., Katare, R., & Das, S. C. (2021). Studies on the safety and the tissue distribution of inhaled high-dose amorphous and crystalline rifampicin in a rat model. International Journal of Pharmaceutics, 597, 120345. doi: 10.1016/j.ijpharm.2021.120345

Journal - Research Article

Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., … Hughes, S. M., … Katare, R. G., … Tong, C.-K. (2021). Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy, 17(1), 1-382. doi: 10.1080/15548627.2020.1797280

Journal - Research Article

Kovanur Sampath, K., Mani, R., Katare, R., Neale, J., Cotter, J., & Tumilty, S. (2021). Thoracic spinal manipulation effect on neuroendocrine response in people with Achilles tendinopathy: A randomized crossover trial. Journal of Manipulative & Physiological Therapeutics, 44(5), 420-431. doi: 10.1016/j.jmpt.2021.06.001

Journal - Research Article

Purvis, N., Kumari, S., Chandrasekera, D., Bellae Papannarao, J., Gandhi, S., van Hout, I., Coffey, S., Bunton, R., Sugunesegran, R., Parry, D., Davis, P., Williams, M. J. A., Bahn, A., & Katare, R. (2021). Diabetes induces dysregulation of microRNAs associated with survival, proliferation and self-renewal in cardiac progenitor cells. Diabetologia, 64, 1422-1435. doi: 10.1007/s00125-021-05405-7

Journal - Research Article

Saw, E. L., Pearson, J. T., Schwenke, D. O., Munasinghe, P. E., Tsuchimochi, H., Rawal, S., Coffey, S., … Bunton, R., Van Hout, I., … Williams, M. J. A., … Fronius, M., & Katare, R. (2021). Activation of the cardiac non-neuronal cholinergic system prevents the development of diabetes-associated cardiovascular complications. Cardiovascular Diabetology, 20, 50. doi: 10.1186/s12933-021-01231-8

Journal - Research Article

Chandrasekera, D. N. K., Neale, J. P. H., van Hout, I., Rawal, S., Coffey, S., Jones, G. T., … Manning, P., Williams, M. J. A., & Katare, R. (2020). Upregulation of microRNA-532 enhances cardiomyocyte apoptosis in the diabetic heart. Apoptosis, 25(5-6), 388-399. doi: 10.1007/s10495-020-01609-1

Journal - Research Article

Khadka, P., Hill, P. C., Zhang, B., Katare, R., Dummer, J., & Das, S. C. (2020). A study on polymorphic forms of rifampicin for inhaled high dose delivery in tuberculosis treatment. International Journal of Pharmaceutics, 587, 119602. doi: 10.1016/j.ijpharm.2020.119602

Journal - Research Article

Knoepp, F., Ashley, Z., Barth, D., Baldin, J.-P., Jennings, M., Kazantseva, M., Saw, E. L., Katare, R., … Fronius, M. (2020). Shear force sensing of epithelial Na+ channel (ENaC) relies on N-glycosylated asparagines in the palm and knuckle domains of αENaC. PNAS, 117(1), 717-726. doi: 10.1073/pnas.1911243117

Journal - Research Article

Lew, J. K.-S., Pearson, J. T., Saw, E., Tsuchimochi, H., Wei, M., Ghosh, N., … Katare, R., & Schwenke, D. O. (2020). Exercise regulates microRNAs to preserve coronary and cardiac function in the diabetic heart. Circulation Research, 127, 1384-1400. doi: 10.1161/circresaha.120.317604

Journal - Research Article

McQuaig, R., Dixit, P., Yamauchi, A., Van Hout, I., Bellae Papannarao, J., Bunton, R., Parry, D., Davis, P., & Katare, R. (2020). Combination of cardiac progenitor cells from the right atrium and left ventricle exhibits synergistic paracrine effects in vitro. Cell Transplantation, 29. doi: 10.1177/0963689720972328

Journal - Research Article

Neale, J. P. H., Pearson, J. T., Thomas, K. N., Tsuchimochi, H., Hosoda, H., Kojima, M., … Jones, G. T., Denny, A. P., Daniels, L. J., Chandrasekera, D., Liu, P., van Rij, A. M., Katare, R., & Schwenke, D. O. (2020). Dysregulation of ghrelin in diabetes impairs the vascular reparative response to hindlimb ischemia in a mouse model; Clinical relevance to peripheral artery disease. Scientific Reports, 10, 13651. doi: 10.1038/s41598-020-70391-6

Journal - Research Article

Paul, S., Ali, A., & Katare, R. (2020). Molecular complexities underlying the vascular complications of diabetes mellitus: A comprehensive review. Journal of Diabetes & Its Complications, 34, 107613. doi: 10.1016/j.jdiacomp.2020.107613

Journal - Research Article

Manning, P., Munasinghe, P. E., Bellae Papannarao, J., Gray, A. R., Sutherland, W., & Katare, R. (2019). Acute weight loss restores dysregulated circulating microRNAs in obese individuals. Journal of Clinical Endocrinology & Metabolism, 104(4), 1239-1248. doi: 10.1210/jc.2018-00684

Journal - Research Article

Rawal, S., Nagesh, P. T., Coffey, S., Van Hout, I., Galvin, I. F., Bunton, R. W., Davis, P., Williams, M. J. A., & Katare, R. (2019). Early dysregulation of cardiac-specific microRNA-208a is linked to maladaptive cardiac remodelling in diabetic myocardium. Cardiovascular Diabetology, 18, 13. doi: 10.1186/s12933-019-0814-4

Journal - Research Article

Fomison-Nurse, I., Saw, E. E. L., Gandhi, S., Munasinghe, P. E., Van Hout, I., Williams, M. J. A., Galvin, I., Bunton, R., Davis, P., Cameron, V., & Katare, R. (2018). Diabetes induces the activation of pro-ageing miR-34a in the heart, but has differential effects on cardiomyocytes and cardiac progenitor cells. Cell Death & Differentiation, 25, 1336-1349. doi: 10.1038/s41418-017-0047-6

Journal - Research Article

Katare, R., Pearson, J. T., Lew, J. K.-S., Wei, M., Tsuchimouchi, H., Du, C.-K., … Schwenke, D. O. (2018). Progressive decrease in coronary vascular function associated with type 2 diabetic heart disease. Frontiers in Physiology, 9, 696. doi: 10.3389/fphys.2018.00696

Journal - Research Article

Akerman, A. P., Lucas, S. J. E., Katare, R., & Cotter, J. D. (2017). Heat and dehydration additively enhance cardiovascular outcomes following orthostatically-stressful calisthenics exercise. Frontiers in Physiology, 8, 756. doi: 10.3389/fphys.2017.00756

Journal - Research Article

Dixit, P., Donnelly, H., Edamatsu, M., Galvin, I., Bunton, R., & Katare, R. (2017). Progenitor cells from atria, ventricle and peripheral blood of the same patients exhibit functional differences associated with cardiac repair. International Journal of Cardiology, 228, 412-421. doi: 10.1016/j.ijcard.2016.11.178

Journal - Research Article

Rawal, S., Munasinghe, E. P., Nagesh, P. T., Lew, J. K. S., Jones, G. T., Williams, M. J. A., Davis, P., Bunton, R. W., Galvin, I. F., Manning, P., Lamberts, R. R., & Katare, R. (2017). Downregulation of miR-15a/b accelerates fibrotic remodelling in the Type-2 diabetic human and mouse heart. Clinical Science, 131(9), 847-863. doi: 10.1042/cs20160916

Journal - Research Article

Rawal, S., Munasinghe, P. E., Shindikar, A., Paulin, J., Cameron, V., Manning, P., Williams, M. J. A., Jones, G. T., Bunton, R., Galvin, I., & Katare, R. (2017). Down-regulation of proangiogenic microRNA-126 and microRNA-132 are early modulators of diabetic cardiac microangiopathy. Cardiovascular Research, 113(1), 90-101. doi: 10.1093/cvr/cvw235

Journal - Research Article

Sampath, K. K., Botnmark, E., Mani, R., Cotter, J. D., Katare, R., Munasinghe, P. E., & Tumilty, S. (2017). Neuro-endocrine response following a thoracic spinal manipulation in healthy men. Journal of Orthopaedic & Sports Physical Therapy, 47(9), 617-627. doi: 10.2519/jospt.2017.7348

Journal - Research Article

Satthenapalli, V. R., Lamberts, R. R., & Katare, R. G. (2017). Challenges in regenerating the diabetic heart: A comprehensive review. Stem Cells, 35(9), 2009-2026. doi: 10.1002/stem.2661

Journal - Research Article

Katare, R., Rawal, S., Munasinghe, P. E., Tsuchimochi, H., Inagaki, T., Fujii, Y., Dixit, P., … Schwenke, D. O. (2016). Ghrelin promotes functional angiogenesis in a mouse model of critical limb ischemia through activation of proangiogenic microRNAs. Endocrinology, 157(2), 432-445. doi: 10.1210/en.2015-1799

Journal - Research Article

Munasinghe, P. E., Riu, F., Dixit, P., Edamatsu, M., Saxena, P., Hamer, N. S. J., Galvin, I. F., Bunton, R. W., Lequeux, S., Jones, G., Lamberts, R. R., … Katare, R. (2016). Type-2 diabetes increases autophagy in the human heart through promotion of Beclin-1 mediated pathway. International Journal of Cardiology, 202, 13-20. doi: 10.1016/j.ijcard.2015.08.111

Journal - Research Article

Rawal, S., Parshu Ram, T., Coffey, S., Williams, M. J. A., Saxena, P., Bunton, R. W., Galvin, I. F., & Katare, R. (2016). Differential expression pattern of cardiovascular microRNAs in the human type-2 diabetic heart with normal ejection fraction. International Journal of Cardiology, 202, 40-43. doi: 10.1016/j.ijcard.2015.08.161

Journal - Research Article

Aiba, T., Noda, T., Hidaka, I., Inagaki, M., Katare, R. G., Ando, M., … Sugimachi, M. (2015). Acetylcholine suppresses ventricular arrhythmias and improves conduction and connexin-43 properties during myocardial ischemia in isolated rabbit hearts. Journal of Cardiovascular Electrophysiology, 26, 678-685. doi: 10.1111/jce.12663

Journal - Research Article

Ascione, R., Rowlinson, J., Avolio, E., Katare, R., Meloni, M., Spencer, H. L., … Madeddu, P. (2015). Migration towards SDF-1 selects angiogenin-expressing bone marrow monocytes endowed with cardiac reparative activity in patients with previous myocardial infarction. Stem Cell Research & Therapy, 6, 53. doi: 10.1186/s13287-015-0028-y

Journal - Research Article

Avolio, E., Meloni, M., Spencer, H. L., Riu, F., Katare, R., Mangialardi, G., … Madeddu, P. (2015). Combined intramyocardial delivery of human pericytes and cardiac stem cells additively improves the healing of mouse infarcted hearts through stimulation of vascular and muscular repair. Circulation Research, 116, e81-e94. doi: 10.1161/circresaha.115.306146

Journal - Research Article

Caporali, A., Meloni, M., Nailor, A., Mitić, T., Shantikumar, S., Riu, F., … Katare, R., … Emanueli, C. (2015). p75NTR-dependent activation of NF-κB regulates microRNA-503 transcription and pericyte-endothelial crosstalk in diabetes after limb ischaemia. Nature Communications, 6(8024). doi: 10.1038/ncomms9024

Journal - Research Article

Dixit, P., & Katare, R. (2015). Challenges in identifying the best source of stem cells for cardiac regeneration therapy. Stem Cell Research & Therapy, 6, 26. doi: 10.1186/s13287-015-0010-8

Journal - Research Article

Gubernator, M., Slater, S. C., Spencer, H. L., Spiteri, I., Sottoriva, A., Riu, F., … Katare, R., … Madeddu, P. (2015). Epigenetic profile of human adventitial progenitor cells correlates with therapeutic outcomes in a mouse model of limb ischemia. Arteriosclerosis, Thrombosis, & Vascular Biology, 35, 675-688. doi: 10.1161/ATVBAHA.114.304989

Journal - Research Article

Purvis, N., Bahn, A., & Katare, R. (2015). The role of microRNAs in cardiac stem cells. Stem Cells International, 2015(2015), 194894. doi: 10.1155/2015/194894

Journal - Research Article

Avolio, E., Gianfranceschi, G., Cesselli, D., Caragnano, A., Athanasakis, E., Katare, R., … Beltrami, A. P. (2014). Ex vivo molecular rejuvenation improves the therapeutic activity of senescent human cardiac stem cells in a mouse model of myocardial infarction. Stem Cells, 32(9), 2373-2385. doi: 10.1002/stem.1728

Journal - Research Article

Katare, R., Stroemer, P., Hicks, C., Stevanato, L., Patel, S., Corteling, R., … Madeddu, P. (2014). Clinical-grade human neural stem cells promote reparative neovascularization in mouse models of hindlimb ischemia. Arteriosclerosis, Thrombosis, & Vascular Biology, 34, 408-418. doi: 10.1161/ATVBAHA.113.302592

Journal - Research Article

Lamberts, R. R., Lingam, S. J., Wang, H.-Y., Bollen, I. A. E., Hughes, G., Galvin, I. F., Bunton, R. W., Bahn, A., Katare, R., Baldi, J. C., Williams, M. J. A., Saxena, P., Coffey, S., & Jones, P. P. (2014). Impaired relaxation despite upregulated calcium-handling protein atrial myocardium from type 2 diabetic patients with preserved ejection fraction. Cardiovascular Diabetology, 13, 72. doi: 10.1186/1475-2840-13-72

Journal - Research Article

Moore, A., Shindikar, A., Fomison-Nurse, I., Riu, F., Munasinghe, P. E., Parshu Ram, T., Saxena, P., Coffey, S., Bunton, R. W., Galvin, I. F., Williams, M. J. A., … Katare, R. (2014). Rapid onset of cardiomyopathy in STZ-induced female diabetic mice involves the downregulation of pro-survival Pim-1. Cardiovascular Diabetology, 13, 68. doi: 10.1186/1475-2840-13-68

Journal - Research Article

Rawal, S., Manning, P., & Katare, R. (2014). Cardiovascular microRNAs: As modulators and diagnostic biomarkers of diabetic heart disease. Cardiovascular Diabetology, 13, 44. doi: 10.1186/1475-2840-13-44

Journal - Research Article

Aditi, Mahajan, N., Rawal, S., & Katare, R. (2013). An insight in to the pathogenesis of diabetic vascular diseases: Role of oxidative stress and antioxidants. Pharmaceutica Analytica Acta, 4(10), 273. doi: 10.4172/2153-2435.1000273

Journal - Research Article

Katare, R. G., & Madeddu, P. (2013). Pericytes from human veins for treatment of myocardial ischemia. Trends in Cardiovascular Medicine, 23, 66-70. doi: 10.1016/j.tcm.2012.09.002

Journal - Research Article

Katare, R., Oikawa, A., Cesselli, D., Beltrami, A. P., Avolio, E., Muthukrishnan, D., Munasinghe, P. E., … Madeddu, P. (2013). Boosting the pentose phosphate pathway restores cardiac progenitor cell availability in diabetes. Cardiovascular Research, 97(1), 55-65. doi: 10.1093/cvr/cvs291

Journal - Research Article

Katare, R., Riu, F., Rowlinson, J., Lewis, A., Holden, R., Meloni, M., … Madeddu, P. (2013). Perivascular delivery of encapsulated mesenchymal stem cells improves postischemic angiogenesis via paracrine activation of VEGF-A. Arteriosclerosis, Thrombosis, & Vascular Biology, 33, 1872-1880. doi: 10.1161/atvbaha.113.301217

Journal - Research Article

Mangialardi, G., Katare, R., Oikawa, A., Meloni, M., Reni, C., Emanueli, C., & Madeddu, P. (2013). Diabetes causes bone marrow endothelial barrier dysfunction by activation of the RhoA-Rho-associated kinase signaling pathway. Arteriosclerosis, Thrombosis, & Vascular Biology, 33, 555-564. doi: 10.1161/ATVBAHA.112.300424

Journal - Research Article

Amadesi, S., Reni, C., Katare, R., Meloni, M., Oikawa, A., Beltrami, A. P., … Madeddu, P. (2012). Role for substance P-based nociceptive signaling in progenitor cell activation and angiogenesis during ischemia in nice and in human subject. Circulation, 125, 1774-1786. doi: 10.1161/CIRCULATIONAHA.111.089763

Journal - Research Article

Katare, R., Caporali, A., Zentilin, L., Avolio, E., Sala-Newby, G., Oikawa, A., … Madeddu, P. (2011). Intravenous gene therapy with PIM-1 via a cardiotropic viral vector halts the progression of diabetic cardiomyopathy through promotion of prosurvival signaling. Circulation Research, 108, 1238-1251. doi: 10.1161/CIRCRESAHA.110.239111

Journal - Research Article

Katare, R., Riu, F., Mitchell, K., Gubernator, M., Campagnolo, P., Cui, Y., … Madeddu, P. (2011). Transplantation of human pericyte progenitor cells improves the repair of infarcted heart through activation of an angiogenic program involving micro-RNA-132. Circulation Research, 109, 894-906. doi: 10.1161/CIRCRESAHA.111.251546

Journal - Research Article

Spinetti, G., Fortunato, O., Cordella, D., Portararo, P., Kränkel, N., Katare, R., … Madeddu, P. (2011). Tissue kallikrein is essential for invasive capacity of circulating proangiogenic cells. Circulation Research, 108, 284-293. doi: 10.1161/CIRCRESAHA.110.236786

Journal - Research Article

Campagnolo, P., Cesselli, D., Al Haj Zen, A., Beltrami, A. P., Kränkel, N., Katare, R., … Madeddu, P. (2010). Human adult vena saphena contains perivascular progenitor cells endowed with clonogenic and proangiogenic potential. Circulation, 121, 1735-1745. doi: 10.1161/CIRCULATIONAHA.109.899252

Journal - Research Article

Handa, T., Katare, R. G., Nishimori, H., Wariishi, S., Fukutomi, T., Yamamoto, M., … Sato, T. (2010). New device for intraoperative graft assessment: HyperEye charge-coupled device camera system. General Thoracic & Cardiovascular Surgery, 58, 68-77. doi: 10.1007/s11748-009-0536-8

Journal - Research Article

Kakinuma, Y., Furihata, M., Akiyama, T., Arikawa, M., Handa, T., Katare, R. G., & Sato, T. (2010). Donepezil, an acetylcholinesterase inhibitor against Alzheimer's dementia, promotes angiogenesis in an ischemic hindlimb model. Journal of Molecular & Cellular Cardiology, 48(4), 680-693. doi: 10.1016/j.yjmcc.2009.11.010

Journal - Research Article

Katare, R. G., Ando, M., Kakinuma, Y., & Sato, T. (2010). Engineered heart tissue: A novel tool to study the ischemic changes of the heart in vitro. PLoS ONE, 5(2), e9275. doi: 10.1371/journal.pone.0009275

Journal - Research Article

Katare, R. G., Ando, M., Kakinuma, Y., Arikawa, M., Yamasaki, F., & Sato, T. (2010). Differential regulation of TNF receptors by vagal nerve stimulation protects heart against acute ischemic injury. Journal of Molecular & Cellular Cardiology, 49(2), 234-244. doi: 10.1016/j.yjmcc.2010.03.007

Journal - Research Article

Katare, R. G., Caporali, A., Oikawa, A., Meloni, M., Emanueli, C., & Maddedu, P. (2010). Vitamin B1 analog benfotiamine prevents diabetes-induced diastolic dysfunction and heart failure through Akt/Pim-1—mediated survival pathway. Circulation: Heart Failure, 3(2), 294-305. doi: 10.1161/CIRCHEARTFAILURE.109.903450

Journal - Research Article

Katare, R., Caporali, A., Emanueli, C., & Madeddu, P. (2010). Benfotiamine improves functional recovery of the infarcted heart via activation of pro-survival G6PD/Akt signaling pathway and modulation of neurohormonal response. Journal of Molecular & Cellular Cardiology, 49, 625-638. doi: 10.1016/j.yjmcc.2010.05.014

Journal - Research Article

Meloni, M., Caporali, A., Graiani, G., Lagrasta, C., Katare, R., van Linthout, S., … Emanueli, C. (2010). Nerve growth factor promotes cardiac repair following myocardial infarction. Circulation Research, 106, 1275-1284. doi: 10.1161/CIRCRESAHA.109.210088

Journal - Research Article

Oikawa, A., Siragusa, M., Quaini, F., Mangialardi, G., Katare, R. G., Caporali, A., … Madeddu, P. (2010). Diabetes mellitus induces bone marrow microangiopathy. Arteriosclerosis, Thrombosis, & Vascular Biology, 30, 498-508. doi: 10.1161/ATVBAHA.109.200154

Journal - Research Article

Siragusa, M., Katare, R., Meloni, M., Damilano, F., Hirsch, E., Emanueli, C., & Madeddu, P. (2010). Involvement of phosphoinositide 3-kinase γ in angiogenesis and healing of experimental myocardial infarction in mice. Circulation Research, 106, 757-768. doi: 10.1161/CIRCRESAHA.109.207449

Journal - Research Article

Barcelos, L. S., Duplaa, C., Kränkel, N., Graiani, G., Invernici, G., Katare, R., … Madeddu, P. (2009). Human CD133+ progenitor cells promote the healing of diabetic ischemic ulcers by paracrine stimulation of angiogenesis and activation of Wnt signaling. Circulation Research, 104, 1095-1102. doi: 10.1161/CIRCRESAHA.108.192138

Journal - Research Article

Handa, T., Katare, R. G., Kakinuma, Y., Arikawa, M., Ando, M., Sasaguri, S., … Sato, T. (2009). Anti-Alzheimer's drug, Donepezil, markedly improves long-term survival after chronic heart failure in mice. Journal of Cardiac Failure, 15(9), 805-811. doi: 10.1016/j.cardfail.2009.05.008

Journal - Research Article

Handa, T., Katare, R. G., Sasaguri, S., & Sato, T. (2009). Preliminary experience for the evaluation of the intraoperative graft patency with real color charge-coupled device camera system: An advanced device for simultaneous capturing of color and near-infrared images during coronary artery bypass graft. Interactive Cardiovascular & Thoracic Surgery, 9, 150-154. doi: 10.1510/icvts.2008.201418

Journal - Research Article

Katare, R. G., Ando, M., Kakinuma, Y., Arikawa, M., Handa, T., Yamasaki, F., & Sato, T. (2009). Vagal nerve stimulation prevents reperfusion injury through inhibition of opening of mitochondrial permeability transition pore independent of the bradycardiac effect. Journal of Thoracic & Cardiovascular Surgery, 137(1), 223-231. doi: 10.1016/j.jtcvs.2008.08.020

Journal - Research Article

Katare, R. G., Kakinuma, Y., Arikawa, M., Yamasaki, F., & Sato, T. (2009). Chronic intermittent fasting improves the survival following large myocardial ischemia by activation of BDNF/VEGF/PI3K signaling pathway. Journal of Molecular & Cellular Cardiology, 46, 405-412. doi: 10.1016/j.yjmcc.2008.10.027

Journal - Research Article

Stone, O. A., Richer, C., Emanueli, C., van Weel, V., Quax, P. H. A., Katare, R., … Madeddu, P. (2009). Critical role of tissue kallikrein in vessel formation and maturation: Implications for therapeutic revascularization. Arteriosclerosis, Thrombosis, & Vascular Biology, 29, 657-664. doi: 10.1161/ATVBAHA.108.182139

Journal - Research Article

Kakinuma, Y., Katare, R. G., Arikawa, M., Muramoto, K., Yamasaki, F., & Sato, T. (2008). A HIF-1alpha-related gene involved in cell protection from hypoxia by suppression of mitochondrial function. FEBS Letters, 582, 332-340. doi: 10.1016/j.febslet.2007.12.026

Journal - Research Article

Kränkel, N., Katare, R. G., Siragusa, M., Barcelos, L. S., Campagnolo, P., Mangialardi, G., … Madeddu, P. (2008). Role of kinin B2 receptor signaling in the recruitment of circulating progenitor cells with neovascularization potential. Circulation Research, 103, 1335-1343. doi: 10.1161/CIRCRESAHA.108.179952

Journal - Research Article

Radhakrishnan, G., Suzuki, R., Maeda, H., Yamamoto, M., Hirose, N., Katare, R. G., … Sasaguri, S. (2008). Inhibition of neointimal hyperplasia developement by MCI-186 is correlated with downregulation of nuclear factor-κB pathway. Circulation Journal, 72, 800-806.

Journal - Research Article

Yamamoto, M., Hironori, M., Hirose, N., Yamamoto, M., Nakagawa, A., Radhakrishnan, G., Katare, R. G., … Sasaguri, S. (2008). Biphasic elevation of bilirubin oxidation during myocardial ischemia reperfusion. Circulation Journal, 72(9), 1520-1527.

Journal - Research Article

Katare, R. G., Zhitian, Z., Sodeoka, M., & Sasaguri, S. (2007). A novel bisindolylmaleimide derivative enhances functional recovery of heart after long-term hypothermic heart preservation. Transplantation, 83(12), 1588-1594. doi: 10.1097/01.tp.0000267019.93796.aa

Journal - Research Article

Katare, R. G., Zhitian, Z., Sodeoka, M., & Sasaguri, S. (2007). Novel bisindolylmaleimide derivative inhibits mitochondrial permeability transition pore and protects the heart from reperfusion injury. Canadian Journal of Physiology & Pharmacology, 85(10), 979-985. doi: 10.1139/Y07-071

Journal - Research Article

Kuwabara, M., Kakinuma, Y., Katare, R. G., Ando, M., Yamasaki, F., Doi, Y., & Sato, T. (2007). Granulocyte colony-stimulating factor activates Wnt signal to sustain gap junction function through recruitment of β-catenin and cadherin. FEBS Letters, 581, 4821-4830. doi: 10.1016/j.febslet.2007.09.007

Journal - Research Article

Yamamoto, M., Maeda, H., Hirose, N., Radhakrishnan, G., Katare, R. G., Hayashi, Y., … Sasaguri, S. (2007). Bilirubin oxidation provoked by nitric oxide radicals predicts the progression of acute cardiac allograft rejection. American Journal of Transplantation, 7, 1897-1906. doi: 10.1111/j.1600-6143.2007.01868.x

Journal - Research Article

Kuwabara, M., Kakinuma, Y., Ando, M., Katare, R. G., Yamasaki, F., Doi, Y., & Sato, T. (2006). Nitric oxide stimulates vascular endothelial growth factor production in cardiomyocytes involved in angiogenesis. Journal of Physiological Sciences, 56(1), 95-101. doi: 10.2170/physiolsci.RP002305

Journal - Research Article

Zhang, Y., Kakinuma, Y., Ando, M., Katare, R. G., Yamasaki, F., Sugiura, T., & Sato, T. (2006). Acetylcholine inhibits the hypoxia-induced reduction of connexin43 protein in rat cardiomyocytes. Journal of Pharmacological Sciences, 101, 214-222. doi: 10.1254/jphs. FP0051023

Journal - Research Article

Sun, D., Katare, R., Sethu, P., Cheng, P., & Fan, Y. (2024). Constructing the vascular or cardiac tissue and organoids: The combination of biomedicine and engineering. Frontiers in Cardiovascular Medicine, 11, 1371074. doi: 10.3389/fcvm.2024.1371074

Journal - Research Other

Kovanur Sampath, K., Belcher, S., Hales, J., Thomson, O. P., Farrell, G., Gisselman, A. S., Katare, R., & Tumilty, S. (2023). The role of micro-RNAs in neuropathic pain: A scoping review. PAIN Reports, 8, e1108. [Review].

Journal - Research Other

Reynolds, A. N., Hood, F., Wilson, R., Ross, A., Neumann, S., Turner, R., Iosua, E., Katare, R., Shahin, A., Kok, Z.-y., … Coffey, S., & Mann, J. (2023). Healthy grocery delivery in the usual care for adults recovering from an acute coronary event: protocol for a three-arm randomised controlled trial. BMJ Open, 13, e074278. doi: 10.1136/bmjopen-2023-074278

Journal - Research Other

Varghese, L. N., Schwenke, D. O., & Katare, R. (2023). Role of noncoding RNAs in cardiac ageing. Frontiers in Cardiovascular Medicine, 10, 1142575. doi: 10.3389/fcvm.2023.1142575

Journal - Research Other

Bellae Papannarao, J., Schwenke, D. O., Manning, P., & Katare, R. (2022). Upregulated miR-200c is associated with downregulation of the functional receptor for severe acute respiratory syndrome coronavirus 2 ACE2 in individuals with obesity [Brief communication]. International Journal of Obesity, 46, 238-241. doi: 10.1038/s41366-021-00984-2

Journal - Research Other

Chandrasekera, D., & Katare, R. (2022). Exosomal microRNAs in diabetic heart disease. Cardiovascular Diabetology, 21, 122. doi: 10.1186/s12933-022-01544-2

Journal - Research Other

Reily-Bell, M., Bahn, A., & Katare, R. (2022). Reactive oxygen species-mediated diabetic heart disease: Mechanisms and therapies. Antioxidants & Redox Signaling, 36(10-12), 608-630. doi: 10.1089/ars.2021.0098

Journal - Research Other

Daniels, L. J., Annandale, M., Koutsifeli, P., Li, X., Bussey, C. T., van Hout, I., Bunton, R. W., … Coffey, S., Katare, R., Lamberts, R. R., … Mellor, K. M. (2021). Elevated myocardial fructose and sorbitol levels are associated with diastolic dysfunction in diabetic patients, and cardiomyocyte lipid inclusions in vitro [Brief communication]. Nutrition & Diabetes, 11, 8. doi: 10.1038/s41387-021-00150-7

Journal - Research Other

Hebbard, C., Lee, B., Katare, R., & Garikipati, V. N. S. (2021). Diabetes, heart failure, and COVID-19: An update. Frontiers in Physiology, 12, 706185. doi: 10.3389/fphys.2021.706185

Journal - Research Other

Kovanur Sampath, K., Katare, R., & Tumilty, S. (2019). Stress axis and osteopathy: A dual hormone approach. International Journal of Osteopathic Medicine, 33-34, 24-30. doi: 10.1016/j.ijosm.2019.05.001

Journal - Research Other

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