Contact Details
- Phone
- +64 3 470 3414
- jeff.erickson@otago.ac.nz
- Position
- Associate Professor
- Department
- Department of Physiology
- Qualifications
- PhD
- Research summary
- Heart disease
Research
My research focuses on investigating the molecular mechanisms that underlie structural heart disease and heart failure, particularly in the context of aging and diabetes. To this end, we have developed a number of novel tools to assess cardiac signaling pathways.
These include:
- FRET-based biosensors to measure kinase activity and localization in living cells
- Custom antibodies to measure biochemical modifications of proteins
- A variety of animal models with enhanced or reduced susceptibility to cardiac pathology
With this research, we hope to contribute new understanding to the molecular basis of cardiac signaling that will culminate in potential clinical therapies for heart disease.
Publications
Power, A. S., Asamudo, E. U., Worthington, L. P. I., Alim, C. C., Parackal, R. E., Wallace, R. S., Ebenebe, O. V., … Erickson, J. R. (2023). Nitric oxide modulates Ca2+ leak and arrhythmias via S-nitrosylation of CaMKII. Circulation Research, 133, 1040-1055. doi: 10.1161/circresaha.123.323571 Journal - Research Article
Okolo, C. A., Khaing, E.-P., Mereacre, V., Wallace, R. S., Munro, M. L., Erickson, J. R., & Jones, P. P. (2023). Direct regulation of the cardiac ryanodine receptor (RyR2) by O-GlcNAcylation. Cardiovascular Diabetology, 22, 276. doi: 10.1186/s12933-023-02010-3 Journal - Research Article
Singh, E., Chandrasekera, D., Wallace, R. S., de Jonge, W., Bunton, R., Parry, D., Davis, P., Erickson, J. R., & Katare, R. (2023, August). Impact of microRNA15b and CaMKIIδ on cardiac fibrosis in diabetes. Poster session presented at the 17th New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Giles, G. I., Erickson, J. R., & Bussey, C. T. (2022). Photoactivation of tDodSNO induces localized vasodilation in rats: Metabolically stable S-nitrosothiols can act as targeted nitric oxide donors in vivo. Nitric Oxide, 129, 53-62. doi: 10.1016/j.niox.2022.10.001 Journal - Research Article
Khaing, E. P., Okolo, C. A., Erickson, J. R., & Jones, P. P. (2022, August-September). Regulation of RyR2 by O-GlcNAcylation. Poster session presented at the 16th New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
2023
Journal - Research Article
Power, A. S., Asamudo, E. U., Worthington, L. P. I., Alim, C. C., Parackal, R. E., Wallace, R. S., Ebenebe, O. V., … Erickson, J. R. (2023). Nitric oxide modulates Ca2+ leak and arrhythmias via S-nitrosylation of CaMKII. Circulation Research, 133, 1040-1055. doi: 10.1161/circresaha.123.323571
Okolo, C. A., Khaing, E.-P., Mereacre, V., Wallace, R. S., Munro, M. L., Erickson, J. R., & Jones, P. P. (2023). Direct regulation of the cardiac ryanodine receptor (RyR2) by O-GlcNAcylation. Cardiovascular Diabetology, 22, 276. doi: 10.1186/s12933-023-02010-3
Conference Contribution - Poster Presentation (not in published proceedings)
Singh, E., Chandrasekera, D., Wallace, R. S., de Jonge, W., Bunton, R., Parry, D., Davis, P., Erickson, J. R., & Katare, R. (2023, August). Impact of microRNA15b and CaMKIIδ on cardiac fibrosis in diabetes. Poster session presented at the 17th New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand.
2022
Journal - Research Article
Giles, G. I., Erickson, J. R., & Bussey, C. T. (2022). Photoactivation of tDodSNO induces localized vasodilation in rats: Metabolically stable S-nitrosothiols can act as targeted nitric oxide donors in vivo. Nitric Oxide, 129, 53-62. doi: 10.1016/j.niox.2022.10.001
Greenman, A. C., Diffee, G. M., Power, A. S., Wilkins, G. T., Gold, O. M. S., Erickson, J. R., & Baldi, J. C. (2022). Treadmill running increases the calcium sensitivity of myofilaments in diabetic rats. Journal of Applied Physiology, 132, 1350-1360. doi: 10.1152/japplphysiol.00785.2021
Journal - Research Other
Roberts-Craig, F. T., Worthington, L. P., O'Hara, S. P., Erickson, J. R., Heather, A. K., & Ashley, Z. (2022). CaMKII splice variants in vascular smooth muscle cells: The next step or redundancy? International Journal of Molecular Sciences, 23, 7916. doi: 10.3390/ijms23147916
Conference Contribution - Published proceedings: Abstract
Power, A., Asamudo, E., Wallace, R., & Erickson, J. (2022). Nitric oxide modulates spontaneous calcium release and ventricular arrhythmias during β-adrenergic signalling through S-nitroslyation of calcium/calmodulin dependent kinase II. Heart, Lung & Circulation, 31(Suppl. 3), (pp. S313). doi: 10.1016/j.hlc.2022.06.544
Conference Contribution - Poster Presentation (not in published proceedings)
Khaing, E. P., Okolo, C. A., Erickson, J. R., & Jones, P. P. (2022, August-September). Regulation of RyR2 by O-GlcNAcylation. Poster session presented at the 16th New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand.
Ashley, Z., Ebenebe, O. V., Erickson, J. R., & Heather, A. K. (2022, August-September). A new scoring system to evaluate atherosclerotic lesions in female ApoE-/- mice. Poster session presented at the 16th New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand.
Roberts-Craig, F., Ashley, Z., Worthington, L. P., O'Hara, S. P., Erickson, J. R., & Heather, A. K. (2022, August-September). Lack of CaMKII is protective against atherosclerosis progression in aging ApoE-/- mice. Poster session presented at the 16th New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand.
Conference Contribution - Verbal presentation and other Conference outputs
Mitchell, B., & Erickson, J. R. (2022, August-September). Structure/function effects of CaMKIIδ ablation in the diabetic heart. Verbal presentation at the 16th New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand.
Yap, S. J. M., & Erickson, J. R. (2022, August-September). Sex differences in arrhythmias in response to nitric oxide signalling. Verbal presentation at the 16th New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand.
Veitch, C. R., & Erickson, J. R. (2022, August-September). Effects of O-GlcNAcylation in DCM: Acute modulation of O-GlcNAc in trabeculae. Verbal presentation at the 16th New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand.
2021
Journal - Research Article
Greenman, A. C., Diffee, G. M., Power, A. S., Wilkins, G. T., Gold, O. M. S., Erickson, J. R., & Baldi, J. C. (2021). Increased myofilament calcium sensitivity is associated with decreased cardiac troponin I phosphorylation in the diabetic rat heart. Experimental Physiology, 106, 2235-2247. doi: 10.1113/ep089730
Hegyi, B., Fasoli, A., Ko, C. Y., Van, B. W., Alim, C. C., Shen, E. Y., … Erickson, J. R., … Bers, D. M. (2021). CaMKII serine 280 O-GlcNAcylation links diabetic hyperglycemia to proarrhythmia. Circulation Research, 129, 98-113. doi: 10.1161/CIRCRESAHA.120.318402
Ng, Y. H., Okolo, C. A., Erickson, J. R., Baldi, J. C., & Jones, P. P. (2021). Protein O-GlcNAcylation in the heart. Acta Physiologica, 233, e13696. doi: 10.1111/apha.13696
Helmstadter, K. G., Ljubojevic-Holzer, S., Wood, B. M., Taheri, K. D., Sedej, S., Erickson, J. R., … Bers, D. M. (2021). CaMKII and PKA-dependent phosphorylation co-regulate nuclear localization of HDAC4 in adult cardiomyocytes. Basic Research in Cardiology, 116, 11. doi: 10.1007/s00395-021-00850-2
Prakoso, D., Lim, S. Y., Erickson, J. R., Wallace, R. S., Lees, J. G., Tate, M., … Ritchie, R. H. (2021). Fine-tuning the cardiac O-GlcNAcylation regulatory enzymes governs the functional and structural phenotype of the diabetic heart. Cardiovascular Research, 118, 212-225. doi: 10.1093/cvr/cvab043
Journal - Research Other
Veitch, C. R., Power, A. S., & Erickson, J. R. (2021). CaMKII inhibition is a novel therapeutic strategy to prevent diabetic cardiomyopathy. Frontiers in Pharmacology, 12, 695401. doi: 10.3389/fphar.2021.695401
Conference Contribution - Published proceedings: Abstract
Asamudo, E. U., & Erickson, J. R. (2021). Acute and chronic effects of nitric oxide exposure on cardiac arrhythmias. New Zealand Medical Journal, 134(1547), (pp. 138). Retrieved from https://www.nzma.org.nz/journal
Worthington, L. P. I., Erickson, J. R., & Heather, A. K. (2021). Calcium calmodulin dependent protein kinase II δ in the pathogenesis of atherosclerosis. New Zealand Medical Journal, 134(1537), (pp. 112). Retrieved from https://www.nzma.org.nz/journal
2020
Journal - Research Article
Ebenebe, O. V., Ashley, Z., Erickson, J. R., & Heather, A. K. (2020). A timing effect of 17-β estradiol on atherosclerotic lesion development in female ApoE−/− mice. International Journal of Molecular Sciences, 21(13), 4710. doi: 10.3390/ijms21134710
Bussey, C. T., Babakr, A. A., Iremonger, R. R., van Hout, I., Wilkins, G. T., Lamberts, R. R., & Erickson, J. R. (2020). Carvedilol and metoprolol are both able to preserve myocardial function in type 2 diabetes. Physiological Reports, 8(5), e14394. doi: 10.14814/phy2.14394
Conference Contribution - Published proceedings: Abstract
Asamudo, E., Wallace, R., Power, A., & Erickson, J. (2020). Modulation of CaMKIIδ aactivity by nitric oxide can promote or prevent ß-adrenergic-induced cardiac arrhythmias. Heart, Lung & Circulation, 29(Suppl. 2), (pp. S140). doi: 10.1016/j.hlc.2020.09.244
Ashley, Z., Ebenebe, O., Worthington, L. P. I., Erickson, J., & Heather, A. K. (2020). Understanding the subtleties of development of atherosclerosis and the effect of sex hormones. New Zealand Medical Journal, 133(1518), (pp. 97-98). Retrieved from https://www.nzma.org.nz/journal
2019
Journal - Research Article
Popescu, I., Yin, G., Velmurugan, S., Erickson, J. R., Despa, F., & Despa, S. (2019). Lower sarcoplasmic reticulum Ca2+ threshold for triggering afterdepolarizations in diabetic rat hearts. Heart Rhythm, 16(5), 765-772. doi: 10.1016/j.hrthm.2018.11.001
Conference Contribution - Published proceedings: Abstract
Augustine, R., Barad, Z., Wallace, R., Erickson, J., & Brown, C. (2019). Mapping o-linked glycosylation in the brain during pregnancy. Brain & Neuroscience Advances, 3, PM102. doi: 10.1177/2398212819855490
Asamudo, E., & Erickson, J. (2019). S-nitrosylation as a post-translational modification of CaMKIIδ and its effects on cardiac function. Heart, Lung & Circulation, 28(Suppl. 4), (pp. S228-S229). doi: 10.1016/j.hlc.2019.06.222
Conference Contribution - Poster Presentation (not in published proceedings)
Greenman, A. C., Power, A. S., Erickson, J. R., & Baldi, J. C. (2019, September). Reduced calcium sensitivity occurs without differential total myofilament phosphorylation in a diabetic rat model. Poster session presented at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
Augustine, R. A., Dell, C., Wallace, R. S., Erickson, J. R., & Brown, C. H. (2019, August-September). Do mice with gestational glucose intolerance have increased O-linked glycosylation in the brain? Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
Conference Contribution - Verbal presentation and other Conference outputs
Veitch, C. R., Aitken-Buck, H. M., & Erickson, J. R. (2019, September). The alpha-adrenergic system and CaMKII in diabetic arrhythmia. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
Power, A. S., Wallace, R. S., & Erickson, J. R. (2019, September). Nitric oxide in the heart: A moderator of β-adrenergic signalling? Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
2018
Journal - Research Article
Daniels, L. J., Wallace, R. S., Nicholson, O. M., Wilson, G. A., McDonald, F. J., Jones, P. P., Baldi, J. C., Lamberts, R. R., & Erickson, J. R. (2018). Inhibition of calcium/calmodulin-dependent kinase II restores contraction and relaxation in isolated cardiac muscle from type 2 diabetic rats. Cardiovascular Diabetology, 17, 89. doi: 10.1186/s12933-018-0732-x
Curl, C. L., Danes, V. R., Bell, J. R., Raaijmakers, A. J. A., Ip, W. T. K., Chandramouli, C., … Erickson, J. R., … Delbridge, L. M. D. (2018). Cardiomyocyte functional etiology in heart failure with preserved ejection fraction is distinctive: A new preclinical model. Journal of the American Heart Association, 7(11), e007451. doi: 10.1161/jaha.117.007451
Journal - Research Other
Bussey, C. T., & Erickson, J. R. (2018). Physiology and pathology of cardiac CaMKII. Current Opinion in Physiology, 1, 52-58. doi: 10.1016/j.cophys.2017.07.003
Ebenebe, O. V., Heather, A., & Erickson, J. R. (2018). CaMKII in vascular signalling: “Friend or foe”? Heart, Lung & Circulation, 27(5), 560-567. doi: 10.1016/j.hlc.2017.12.003
Conference Contribution - Published proceedings: Abstract
Greenman, A., Diffee, G., Wallace, R., Lamberts, R., Erickson, J., & Baldi, C. (2018). Reduced myofilament calcium-sensitivity occurs without phosphorylation of cTnI serine 23/24 in human diabetic cardiomyocytes. Heart, Lung & Circulation, 27(Suppl. 2), (pp. S125). doi: 10.1016/j.hlc.2018.06.184
Bussey, C., Iremonger, R., Lamberts, R., & Erickson, J. (2018). Myocardial impairments preceding overt in vivo cardiac dysfunction are prevented by beta blockade in type 2 diabetic Zucker diabetic fatty rats. Heart, Lung & Circulation, 27(Suppl. 2), (pp. S114). doi: 10.1016/j.hlc.2018.06.158
Conference Contribution - Poster Presentation (not in published proceedings)
Khan, N., Smeeton, J. H., Lamberts, R. R., & Erickson, J. R. (2018, August). Role of CaMKII and alpha-adrenergic stimulation in diabetic heart function. Poster session presented at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
Worthington, L. P. I., Erickson, J. R., Jones, G. T., & Heather, A. K. (2018, August). CaMKII inhibition as a novel target to control the early progression of atherosclerosis. Poster session presented at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
Smeeton, J. H., Khan, N. A., Bussey, C. T., Erickson, J. R., & Lamberts, R. R. (2018, August). α-adrenergic control of the diabetic heart. Poster session presented at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
Barad, Z., Augustine, R. A., Wallace, R. S., Erickson, J. R., & Brown, C. H. (2018, August). Mapping O-linked glycosylation in the brain during pregnancy. Poster session presented at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
Conference Contribution - Verbal presentation and other Conference outputs
Okolo, C. A., McLay, J. C., McLachlan, J. J., Munro, M., Tanner, C., Chakraborty, A. D., Erickson, J. R., & Jones, P. P. (2018, August). Regulation of RyR2 by O-linked glycosylation. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
2017
Conference Contribution - Published proceedings: Abstract
Bussey, C. T., Wallace, R. S., Lamberts, R. R., & Erickson, J. R. (2017). Beta-blockade restores myocardial function in type 2 diabetic rats via CaMKII-independent mechanisms. Journal of Molecular & Cellular Cardiology, 109(Suppl.), (pp. 34). doi: 10.1016/j.yjmcc.2017.06.002
Ebenebe, O., Heather, A., & Erickson, J. (2017). The role of CaMKII in atherosclerotic plaque calcification in the ApoE-null mouse. Heart, Lung & Circulation, 26(Suppl. 2), (pp. S65). doi: 10.1016/j.hlc.2017.06.051
Cserne Szappanos, H., Erickson, J., & Hool, L. (2017). Nitric oxide potentiates the effect of calcium/calmodulin-dependent kinase II on Cav1.2 Protein. Heart, Lung & Circulation, 26(Suppl. 2), (pp. S109). doi: 10.1016/j.hlc.2017.06.152
Conference Contribution - Poster Presentation (not in published proceedings)
Worthington, L. P. I., Erickson, J. R., Jones, G. T., & Heather, A. K. (2017, September). CaMKII inhibition reduces foam cell lesion development in the brachiocephalic artery of apolipoprotein E-/- knockout mice. Poster session presented at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
Iremonger, R. R., Bussey, C. T., & Erickson, J. R. (2017, September). The role of beta blockers in cardiac structural remodelling. Poster session presented at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
Conference Contribution - Verbal presentation and other Conference outputs
Bussey, C. T., Erickson, J. R., Fronius, M., & Ashley, Z. (2017, September). The role of vascular ENaC in impaired flow-mediated responses of carotid arteries in diabetes. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
van Hout, I., Nicholson, O., Erickson, J. R., Lamberts, R. R., & Jones, P. P. (2017, September). Alterations in calcium handling proteins in diabetic and non-diabetic patient with or without post-operative atrial fibrillation. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
Calverley, J. R., Erickson, J. R., & Lamberts, R. R. (2017, September). Determining the physiological importance of CaMKII in alpha-adrenergic (α-AR) regulation of heart function in mice. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
Daniels, L. J., Lamberts, R. R., McDonald, F., Pereira, L., Bers, D. M., & Erickson, J. R. (2017, September). The role of calcium calmodulin dependent protein kinase II in type 2 diabetic cardiac dysfunction. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
Ebenebe, O. V., Heather, A. K., & Erickson, J. R. (2017, September). The role of CaMKII in atherosclerotic plaque calcification in the ApoE-null mouse. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
2016
Conference Contribution - Published proceedings: Abstract
Erickson, J., Lamberts, R., & Daniels, L. (2016). CaMKII inhibition restores contractility in trabeculae from diabetic rats. Heart, Lung & Circulation, 25(Suppl. 2), (pp. S84-S85). doi: 10.1016/j.hlc.2016.06.197
Conference Contribution - Poster Presentation (not in published proceedings)
Bussey, C., Mugloo, S., Erickson, J., Fronius, M., & Ashley, Z. (2016, December). β-blockers rescue flow-mediated responses of carotid arteries in diabetes through a reduction in vascular ENaC activity? Poster session presented at the Joint International Meeting of the Renal Scientists of the Australia and New Zealand Society of Nephrology and the Kidney in Health and Disease Network: Translational Medicine: Innovations in Renal Research, Blenheim, New Zealand.
Ebenebe, O. V., Heather, A. K., & Erickson, J. R. (2016, August-September). 17β-Estradiol induced calcification and altered CaMKII expression in a mouse model of atherosclerosis. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Nelson, New Zealand.
Denny, A., Erickson, J. R., Jones, P. P., & Heather, A. K. (2016, August-September). RyR2 leak and CaMKII post-translational modifications in the heart: Can this explain the altered Ca2+ handling in FSHD? Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Nelson, New Zealand.
Worthington, L. P., Erickson, J. R., & Heather, A. K. (2016, August-September). CaMKII mediates vascular smooth muscle cell activation central to the development of atherosclerosis. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Nelson, New Zealand.
Okolo, C. A., McLachlan, J. J., McLay, J. C., Erickson, J. R., & Jones, P. P. (2016, August-September). O-GlcNAcylation regulates RyR2 function directly. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Nelson, New Zealand.
Ebenebe, O. V., Heather, A. K., & Erickson, J. R. (2016, August). 17β-Estradiol induced calcification and alters CaMKII expression in a mouse model of atherosclerosis. Poster session presented at the Medical Sciences Congress (MedSci), Nelson, New Zealand.
Okolo, C. A., McLachlan, J. J., McLay, J., Erickson, J. R., & Jones, P. P. (2016, August). O-GlcNAcylation regulates RyR2 function directly. Poster session presented at the Medical Sciences Congress (MedSci), Nelson, New Zealand.
Denny, A., Jones, P. P., Erickson, J. R., & Heather, A. K. (2016, August). Oxidised CaMKII: A novel mechanism in the pathophysiology of FSHD. Poster session presented at the Medical Sciences Congress (MedSci), Nelson, New Zealand.
Conference Contribution - Verbal presentation and other Conference outputs
Daniels, L. J., McDonald, F. J., Lamberts, R. R., & Erickson, J. R. (2016, August-September). The effects of CaMKII inhibition on post-rest behavior and spontaneous contractions in isolated Zucker diabetic fatty rat cardiac muscle. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Nelson, New Zealand.
Worthington, L. P., Erickson, J. R., & Heather, A. K. (2016, August). CaMKII activation in endothelial dysfunction. Verbal presentation at the Medical Sciences Congress (MedSci), Nelson, New Zealand.
Daniels, L. J., Lamberts, R. R., McDonald, F. J., & Erickson, J. R. (2016, August). CaMKII inhibition restores contractile performance in cardiac muscle from a rat model of type 2 diabetes. Verbal presentation at the Medical Sciences Congress (MedSci), Nelson, New Zealand.
2015
Journal - Research Article
Erickson, J. R., Nichols, C. B., Uchinoumi, H., Stein, M. L., Bossuyt, J., & Bers, D. M. (2015). S-nitrosylation induces both autonomous activation and inhibition of calcium/calmodulin-dependent protein kinase II δ. Journal of Biological Chemistry, 290(42), 25646-25656. doi: 10.1074/jbc.M115.650234
Daniels, L., Bell, J. R., Delbridge, L. M. D., McDonald, F. J., Lamberts, R. R., & Erickson, J. R. (2015). The role of CaMKII in diabetic heart dysfunction. Heart Failure Reviews, 20(5), 589-600. doi: 10.1007/s10741-015-9498-3
Grimm, M., Ling, H., Willeford, A., Pereira, L., Gray, C. B. B., Erickson, J. R., … Brown, J. H. (2015). CaMKIIδ mediates β-adrenergic effects on RyR2 phosphorylation and SR Ca2+ leak and the pathophysiological response to chronic β-adrenergic stimulation. Journal of Molecular & Cellular Cardiology, 85, 282-291. doi: 10.1016/j.yjmcc.2015.06.007
Pereira, L., Rehman, H., Lao, D. H., Erickson, J. R., Bossuyt, J., Chen, J., & Bers, D. M. (2015). Novel Epac fluorescent ligand reveals distinct Epac1 vs. Epac2 distribution and function in cardiomyocytes. PNAS, 112(13), 3991-3996. doi: 10.1073/pnas.1416163112
Bell, J. R., Raaijmakers, A. J. A., Curl, C. L., Reichelt, M. E., Harding, T. W., Bei, A., … Erickson, J. R., … Delbridge, L. M. D. (2015). Cardiac CaMKIIδ splice variants exhibit target signaling specificity and confer sex-selective arrhythmogenic actions in the ischemic-reperfused heart. International Journal of Cardiology, 181, 288-296. doi: 10.1016/j.ijcard.2014.11.159
Conference Contribution - Verbal presentation and other Conference outputs
Ebenebe, O. V., Heather, A. K., & Erickson, J. R. (2015, August-September). The role of CaMKII activation in atheroma formation in the ApoE-null mouse. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
2014
Journal - Research Article
Jian, Z., Han, H., Zhang, T., Puglisi, J., Izu, L. T., Shaw, J. A., … Erickson, J. R., … Chen-Izu, Y. (2014). Mechanochemotransduction during cardiomyocyte contraction is mediated by localized nitric oxide signaling. Science Signaling, 7(317), ra27. doi: 10.1126/scisignal.2005046
Zhang, D.-M., Chai, Y., Erickson, J. R., Brown, J. H., Bers, D. M., & Lin, Y.-F. (2014). Intracellular signalling mechanism responsible for modulation of sarcolemmal ATP-sensitive potassium channels by nitric oxide in ventricular cardiomyocytes. Journal of Physiology, 592(5), 971-990. doi: 10.1113/jphysiol.2013.264697
Bell, J. R., Erickson, J. R., & Delbridge, L. M. D. (2014). Ca2+/calmodulin dependent kinase II: A critical mediator in determining reperfusion outcomes in the heart? Clinical & Experimental Pharmacology & Physiology, 41(11), 940-946. doi: 10.1111/1440-1681.12301
Erickson, J. R. (2014). Mechanisms of CaMKII activation in the heart. Frontiers in Pharmacology, 5, 59. doi: 10.3389/fphar.2014.00059
Conference Contribution - Verbal presentation and other Conference outputs
Erickson, J. (2014, November). Activation mechanisms of CaMKII in the heart. Verbal presentation at the HeartOtago First Australasian Symposium: Bench to Bedside and Back: New Advances in Cardiovascular Research, Dunedin, New Zealand.
2013
Journal - Research Article
Erickson, J. R., Pereira, L., Wang, L., Han, G., Ferguson, A., Dao, K., … Bers, D. M. (2013). Diabetic hyperglycaemia activates CaMKII and arrhythmias by O-linked glycosylation. Nature, 502, 372-376. doi: 10.1038/nature12537
Conference Contribution - Verbal presentation and other Conference outputs
Erickson, J. R. (2013, August). A novel mechanism for activation of calcium/calmodulin dependent kinase II during hyperglycemia. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.