Contact Details
- Phone
- +64 3 479 5462
- simon.guan@otago.ac.nz
University Links
- Position
- Senior Lecturer
- Department
- Department of Oral Diagnostic and Surgical Sciences
- Qualifications
- BDS DClinDent(Oral Medicine) MBChB FOMAA
- Research summary
- Oral mucosal diseases and orofacial pain
- Teaching
- Postgraduate (DClinDent) and undergraduate (BDS)
- Memberships
- FOMMA
- Clinical
- Registered Oral Medicine Specialist In New Zealand and Clinical Supervisor for Oral Medicine DClinDent and BDS clinics
Research
As an Oral Medicine Specialist, I have a special interest in oral diseases with systemic complications and systemic diseases with oral manifestations.
My main research interest is in oral cancer, particularly developing prognostic or predictive molecular markers that can be used for assessment of the severity of the disease, prognosis and therapy.
Publications
Mei, L., Jin, C., Na, A., Marra, J., Guan, S., & Choi, J. (2024). Biomechanical aging behaviour of clear aligners. Australian Orthodontic Journal, 40(1), 60-66. doi: 10.2478/aoj-2024-0006)
Mei, L., Wang, Z., Guo, O., Zhang, L., & Guan, G. (2024). TikTok talks teeth: A quantitative and qualitative analysis of fixed appliance related TikTok videos. Australasian Orthodontic Journal, 40(1), 50-59. doi: 10.2478/aoj-2024-0005
Polonowita, A., Mei, L., & Guan, G. (2024). The deconstruction of chronic orofacial pain and a hiding inhibition pathway of orofacial pain: The trigeminal proprioceptive mesencephalic periaqueductal gray pathway. New Zealand Medical Journal/Te ara tika o te hauora hapori, 137(1588), 67-79. Retrieved from https://nzmj.org.nz/
Avery, N., Fukushima, K., Guan, G., Praganta, J., Rich, A., Vincent, M., & Robertson, S. (2024). Familial aggregation of keratinising desquamative squamous metaplasia in the urinary tract. BJU International, 133(Suppl. 3), 15-17. doi: 10.1111/bju.16160
Guan, G., & Polonowita, A. (2023). Immunology and the oral cavity. In R. Balasubramaniam, S.-C. Yeoh, T. Yap & S. R. Prabhu (Eds.), Oral medicine: A clinical guide. (pp. 319-323). Cham, Switzerland: Springer. doi: 10.1007/978-3-031-36797-7_49
Guan, G., & Polonowita, A. (2023). Allergy and the mouth. In R. Balasubramaniam, S.-C. Yeoh, T. Yap & S. R. Prabhu (Eds.), Oral medicine: A clinical guide. (pp. 103-105). Cham, Switzerland: Springer. doi: 10.1007/978-3-031-36797-7_24
Chapter in Book - Research
Guan, G., & Polonowita, A. (2023). Immunology and the oral cavity. In R. Balasubramaniam, S.-C. Yeoh, T. Yap & S. R. Prabhu (Eds.), Oral medicine: A clinical guide. (pp. 319-323). Cham, Switzerland: Springer. doi: 10.1007/978-3-031-36797-7_49
Chapter in Book - Research
Polonowita, A., & Guan, G. (2023). Aphthae and recurrent aphthous stomatitis. In R. Balasubramaniam, S.-C. Yeoh, T. Yap & S. R. Prabhu (Eds.), Oral medicine: A clinical guide. (pp. 213-215). Cham, Switzerland: Springer. doi: 10.1007/978-3-031-36797-7_49
Chapter in Book - Research
Polonowita, A., & Guan, G. (2023). Differential diagnosis of oral ulceration. In R. Balasubramaniam, S.-C. Yeoh, T. Yap & S. R. Prabhu (Eds.), Oral medicine: A clinical guide. (pp. 205-207). Cham, Switzerland: Springer. doi: 10.1007/978-3-031-36797-7_49
Chapter in Book - Research
Polonowita, A., & Guan, G. (2023). Infection-related oral ulceration. In R. Balasubramaniam, S.-C. Yeoh, T. Yap & S. R. Prabhu (Eds.), Oral medicine: A clinical guide. (pp. 217-219). Cham, Switzerland: Springer. doi: 10.1007/978-3-031-36797-7_49
Chapter in Book - Research
Polonowita, A., & Guan, G. (2023). Traumatic oral ulceration. In R. Balasubramaniam, S.-C. Yeoh, T. Yap & S. R. Prabhu (Eds.), Oral medicine: A clinical guide. (pp. 209-211). Cham, Switzerland: Springer. doi: 10.1007/978-3-031-36797-7_50
Chapter in Book - Research
Avery, N., Fukushima, K., Guan, G., Praganta, J., Rich, A., Vincent, M., & Robertson, S. (2024). Familial aggregation of keratinising desquamative squamous metaplasia in the urinary tract. BJU International, 133(Suppl. 3), 15-17. doi: 10.1111/bju.16160
Journal - Research Article
Mei, L., Jin, C., Na, A., Marra, J., Guan, S., & Choi, J. (2024). Biomechanical aging behaviour of clear aligners. Australian Orthodontic Journal, 40(1), 60-66. doi: 10.2478/aoj-2024-0006)
Journal - Research Article
Mei, L., Wang, Z., Guo, O., Zhang, L., & Guan, G. (2024). TikTok talks teeth: A quantitative and qualitative analysis of fixed appliance related TikTok videos. Australasian Orthodontic Journal, 40(1), 50-59. doi: 10.2478/aoj-2024-0005
Journal - Research Article
Au, C., Li, J., Jin, L., Wu, T., Guan, G., & Mei, L. (2023). Non-attendance of appointments at the orthodontic clinic. Australasian Orthodontic Journal, 39(2), 185-193. doi: 10.2478/aoj-2023-0035
Journal - Research Article
Guan, G., Mei, L., Yu, C., Tan, Y., & Han, C. (2023). Patient-centred care attitudes and knowledge: A national study of BDS students in New Zealand. BMC Medical Education, 23, 516. doi: 10.1186/s12909-023-04496-7
Journal - Research Article
Li, M., & Guan, G. (2023). Profilometry and atomic force microscopy for surface characterization. Nano TransMed, 2(1), 69-73. doi: 10.26599/NTM.2023.9130017
Journal - Research Article
Han, C., Mei, L., Liu, A., Ya Mohammad Hassan, S., Polonowita, A., & Guan, G. (2022). Oral medicine services: A two-centre study of 99,603 patients between 2015 and 2020. Journal of International Medical Research, 50(8). doi: 10.1177/03000605221115384
Journal - Research Article
Polonowita, A., Guan, G., Thomson, W. M., & Martin-Hendrie, R. (2022). Using telehealth for oral medicine patient management during the COVID-19 lockdown. Oral Surgery, 15, 291-304. doi: 10.1111/ors.12721
Journal - Research Article
Ratnayake, J., Guan, G., Polonowita, A., Gray, A. R., Loch, C., Li, K. C., Waddell, J. N., Lyons, K., & Brunton, P. A. (2022). Measuring changes in jaw opening forces to assess the degree of improvement in patients with temporomandibular disorders. Applied Sciences, 12(3), 1224. doi: 10.3390/app12031224
Journal - Research Article
Yu, W. W., Goh, R., Cheong, E., Guan, G., Jin, C., Cannon, R. D., Farella, M., & Mei, L. (2022). Prevalence of halitosis among young adults in Dunedin, New Zealand. International Journal of Dental Hygiene, 20, 700-707. doi: 10.1111/idh.12609
Journal - Research Article
Wang, Y., Bai, S., Cheng, Q., Zeng, Y., Xu, X., & Guan, G. (2021). Naringenin promotes SDF-1/CXCR4 signaling pathway in BMSCs osteogenic differentiation. Folia Histochemica et Cytobiologica, 59(1), 66-73. doi: 10.5603/FHC.a2021.0008
Journal - Research Article
Won, J., Guan, G., Mei, L., Ma, T., Lai, Y., Zafar, S., Mei, M. L., & Thomson, W. M. (2021). A multicenter study of dental curricula in Asia/Pacific nations: The views and experiences of final-year dental students. Journal of Dental Education, 85, 660-668. doi: 10.1002/jdd.12515
Journal - Research Article
Guan, G., Lau, J., Yew, V., U, J., Qu, W., Lam, J., Polonowita, A., & Mei, L. (2020). Referrals by general dental practitioners and medical practitioners to oral medicine specialists in New Zealand: A study to develop protocol guidelines. Oral Surgery, Oral Medicine, Oral Pathology & Oral Radiology, 130(1), 43-51.e5. doi: 10.1016/j.oooo.2020.03.050
Journal - Research Article
Guan, G., Mei, L., Polonowita, A., Hussaini, H., Seo, B., & Rich, A. M. (2020). Malignant transformation in oral lichen planus and lichenoid lesions: A 14-year longitudinal cohort study of 829 patients in New Zealand. Oral Surgery, Oral Medicine, Oral Pathology & Oral Radiology, 130(4), 411-418. doi: 10.1016/j.oooo.2020.07.002
Journal - Research Article
Guo, J., Li, L., Guan, G., Bennani, F., & Mei, L. (2020). Oral health knowledge and practice among orthodontic clients in China and New Zealand. Canadian Journal of Dental Hygiene / Journal canadien de l'hygiène dentaire, 54(3), 124-132.
Journal - Research Article
Guo, J., Low, K. S., Mei, L., Li, J. H., Qu, W., & Guan, G. (2020). Use of traditional medicine for dental care by different ethnic groups in New Zealand. BMC Oral Health, 20, 280. doi: 10.1186/s12903-020-01272-7
Journal - Research Article
Guo, J., Yan, X., Li, S., Van der Walt, J., Guan, G., & Mei, L. (2020). Quantitative and qualitative analyses of orthodontic-related videos on YouTube. Angle Orthodontist, 90(3), 411-418. doi: 10.2319/082019-542.1
Journal - Research Article
Jiang, B., Xu, J., Zhou, Y., Mao, J., Guan, G., Xu, X., & Mei, L. (2020). Estrogen enhances osteogenic differentiation of human periodontal ligament stem cells by activating the Wnt/β-catenin signaling pathway. Journal of Craniofacial Surgery, 31, 583-587. doi: 10.1097/scs.0000000000006226
Journal - Research Article
Mei, L., Lai, Y., Lee, P., Ng, A., Tan, K., Zafar, S., & Guan, G. (2020). Final year dental students' career plans, work patterns, work-life balance and domestic life in New Zealand and Australia. European Journal of Dental Education, 24(4), 679-686. doi: 10.1111/eje.12556
Journal - Research Article
Ratnayake, J. T., Ross, E. D., Dias, G. J., Shanafelt, K. M., Taylor, S. S., Gould, M. L., Guan, G., & Cathro, P. R. (2020). Preparation, characterisation and in-vitro biocompatibility study of a bone graft developed from waste bovine teeth for bone regeneration. Materials Today Communications, 22, 100732. doi: 10.1016/j.mtcomm.2019.100732
Journal - Research Article
Ratnayake, J., Guan, G., Polonowita, A., Li, K. C., Gray, A., Waddell, J. N., Loch, C., & Brunton, P. A. (2020). Can the measurement of jaw-opening forces assist in the diagnosis of temporomandibular disorders? Journal of Oral & Facial Pain & Headache, 34(3), 199-205. doi: 10.11607/ofph.2587
Journal - Research Article
Xu, J., Zhao, X., Zeng, J., Yu, J.-H., Guan, S., Xu, X.-M., & Mei, L. (2020). Role of autophagy in the periodontal ligament reconstruction during orthodontic tooth movement in rats. Journal of Dental Sciences, 15, 351-363. doi: 10.1016/j.jds.2020.02.005
Journal - Research Article
Xu, X., Shum, M., Ting, A., Mei, L., & Guan, G. (2020). Estimation of jaw-opening forces, energy expenditure and jaw-opening patterns in adults. Archives of Oral Biology, 117, 104836. doi: 10.1016/j.archoralbio.2020.104836
Journal - Research Article
Guan, G., Bakr, M. M., Firth, N., & Love, R. M. (2018). Expression of cyclin D1 correlates with p27KIP1 and regulates the degree of oral dysplasia and squamous cell carcinoma differentiation. Oral Surgery, Oral Medicine, Oral Pathology & Oral Radiology, 126(2), 174-183. doi: 10.1016/j.oooo.2018.01.015
Journal - Research Article
Wilson, E., Grant, B., Tobin-Stickings, R., Lewthwaite, H., Franklin, G., Oh, S., Guan, S., Borowsky, T., Thwaites, K., Leaper, T., Lee, J., Jack, S., & Sopoaga, F. (2018). Traditional medicine use in the Pacific community in Dunedin New Zealand. Pacific Health Dialog, 21(1), 17-26. doi: 10.26635/phd.2018.903
Journal - Research Article
Guan, G., & Firth, N. (2015). Oral manifestations as an early clinical sign of acute myeloid leukaemia: A case report. Australian Dental Journal, 60(1), 123-127. doi: 10.1111/adj.12272
Journal - Research Article
Polonowita, A., Mei, L., & Guan, G. (2024). The deconstruction of chronic orofacial pain and a hiding inhibition pathway of orofacial pain: The trigeminal proprioceptive mesencephalic periaqueductal gray pathway. New Zealand Medical Journal/Te ara tika o te hauora hapori, 137(1588), 67-79. Retrieved from https://nzmj.org.nz/
Journal - Research Other
El Tantawi, M., Lam, W. Y. H., Giraudeau, N., Virtanen, J. I., Matanhire, C., Chifamba, T., … Hasmun, N., Guan, G., Polonowita, A., … Folayan, M. O. (2023). Teledentistry from research to practice: A tale of nineteen countries. Frontiers in Oral Health, 4, 1188557. doi: 10.3389/froh.2023.1188557
Journal - Research Other
Guan, G., Cannon, R. D., Coates, D. E., & Mei, L. (2023). Effect of the Rho-kinase/ROCK signaling pathway on cytoskeleton components. Genes, 14, 272. doi: 10.3390/genes14020272
Journal - Research Other
Guan, G., He, Y., & Mei, L. (2022). Atomic force microscopy: A nanobiotechnology for cellular research. Nano TransMed, 1, e9130004. doi: 10.26599/NTM.2022.9130004
Journal - Research Other
Guan, G., Rich, A. M., Polonowita, A., & Mei, L. (2022). Review of taste and taste disturbance in COVID-19 patients. New Zealand Medical Journal, 135(1549), 81-91. Retrieved from https://www.nzma.org.nz/journal
Journal - Research Other
Li, B., Guan, G., Mei, L., Jiao, K., & Li, H. (2021). Pathological mechanism of chondrocytes and the surrounding environment during osteoarthritis of temporomandibular joint. Journal of Cellular & Molecular Medicine, 25, 4902-4911. doi: 10.1111/jcmm.16514
Journal - Research Other
Lv, N., Sun, M., Polonowita, A., Mei, L., & Guan, G. (2021). Management of oral medicine emergencies during COVID-19: A study to develop practice guidelines. Journal of Dental Sciences, 16, 493-500. doi: 10.1016/j.jds.2020.07.016
Journal - Research Other
Guan, G., Won, J., Mei, L., & Polonowita, A. (2020). Extensive adipose replacement of the parotid glands: An unusual presentation of sialadenosis: A case report and literature review. Oral Surgery, 13, 41-47. doi: 10.1111/ors.12442
Journal - Research Other
Sun, M., Lv, N., Xiao, Y., Li, J., & Guan, G. (2020). A rare case of accessory maxilla: A case report and literature review of Tessier no. 7 clefts. Journal of International Medical Research, 48(5), 1-9. doi: 10.1177/0300060520925680
Journal - Research Other
Bakr, M. M., Guan, S., Firth, N., & Love, R. M. (2018). Cyclin D1 and P27KIP1: The gatekeepers of dysplasia. Journal of Immunological Sciences, 2(3), 30-39. doi: 10.29245/2578-3009/2018/3.1142
Journal - Research Other
Guan, G., & Mei, L. (2018). A case series: Zinc deficiency as a potential contributor to oral dysgeusia. Modern Approaches in Dentistry & Oral Health Care, 2(5), 198-203. doi: 10.32474/MADOHC.2018.02.000146
Journal - Research Other