Professor Peter Fineran

Lundgren, M., Charpentier, E., & Fineran, P. C. (Eds.). (2015). CRISPR: Methods and protocols: Methods in molecular biology (Vol. 1311). Humana Press, 366p. doi: 10.1007/978-1-4939-2687-9

Edited Book - Research

Bergmann, J. M., Fineran, P. C., Petty, N. K., & Salmond, G. P. C. (2019). Transduction: The transfer of host DNA by bacteriophages. In T. M. Schmidt (Ed.), Encyclopedia of microbiology. (pp. 458-473). Academic Press. doi: 10.1016/B978-0-12-801238-3.11350-9

Chapter in Book - Research

Fagerlund, R. D., Ferguson, T. J., Maxwell, H. W. R., Opel-Reading, H. K., Krause, K. L., & Fineran, P. C. (2019). Reconstitution of CRISPR adaptation in vitro and its detection by PCR. In S. Bailey (Ed.), Methods in enzymology (Vol. 616: CRISPR-Cas enzymes). (pp. 411-433). Cambridge, MA: Academic Press. doi: 10.1016/bs.mie.2018.10.024

Chapter in Book - Research

Biswas, A., Fineran, P. C., & Brown, C. M. (2015). Computational detection of CRISPR/crRNA targets. In M. Lundgren, E. Charpentier & P. C. Fineran (Eds.), CRISPR: Methods in molecular biology (Vol. 1311). (pp. 77-89). New York, NY: Humana Press. doi: 10.1007/978-1-4939-2687-9_5

Chapter in Book - Research

Fineran, P. C., Petty, N. K., & Salmond, G. P. C. (2009). Transduction: Host DNA transfer by bacteriophages. In M. Schaechter (Ed.), Encyclopedia of microbiology (Vol. 3). (3rd ed.) (pp. 666-679). Oxford, UK: Elsevier.

Chapter in Book - Research

Mayo-Muñoz, D., Pinilla-Redondo, R., Camara-Wilpert, S., Birkholz, N., & Fineran, P. C. (2024). Inhibitors of bacterial immune systems: Discovery, mechanisms and applications. Nature Reviews Genetics. Advance online publication. doi: 10.1038/s41576-023-00676-9

Journal - Research Article

Sisson, H. M., Fagerlund, R. D., Jackson, S. A., Briers, Y., Warring, S. L., & Fineran, P. C. (2024). Antibacterial synergy between a phage endolysin and citric acid against the Gram-negative kiwifruit pathogen Pseudomonas syringae pv. actinidiae. Applied & Environmental Microbiology. Advance online publication. doi: 10.1128/aem.01846-23

Journal - Research Article

Sisson, H. M., Jackson, S. A., Fagerlund, R. D., Warring, S. L., & Fineran, P. C. (2024). Gram-negative endolysins: Overcoming the outer membrane obstacle [Review]. Current Opinion in Microbiology, 78, 102433. doi: 10.1016/j.mib.2024.102433

Journal - Research Article

Sitter, L., Schoof, M., Glare, T. R., Cox, M. P., Fineran, P. C., Gardner, P. P., & Hurst, M. R. H. (2024). Serratia-based toxin cluster elements are associated with a type I fimbria. MicrobiologyOpen, 13, e1395. doi: 10.1002/mbo3.1395

Journal - Research Article

Camara-Wilpert, S., Mayo-Muñoz, D., Russel, J., Fagerlund, R. D., Madsen, J. S., Fineran, P. C., … Pinilla-Redondo, R. (2023). Bacteriophages suppress CRISPR–Cas immunity using RNA-based anti-CRISPRs. Nature, 623, 601-607. doi: 10.1038/s41586-023-06612-5

Journal - Research Article

Mahler, M., Costa, A. R., van Beljouw, S. P. B., Fineran, P. C., & Brouns, S. J. J. (2023). Approaches for bacteriophage genome engineering [Review]. Trends in Biotechnology, 41(5), 669-685. doi: 10.1016/j.tibtech.2022.08.008

Journal - Research Article

Mahler, M., Malone, L. M., van den Berg, D. F., Smith, L. M., Brouns, S. J. J., & Fineran, P. C. (2023). An OmpW-dependent T4-like phage infects Serratia sp. ATCC 39006. Microbial Genomics, 9(3), 000968. doi: 10.1099/mgen.0.000968

Journal - Research Article

Shearer, H. L., Pace, P. E., Smith, L. M., Fineran, P. C., Matthews, A. J., Camilli, A., Dickerhof, N., & Hampton, M. B. (2023). Identification of Streptococcus pneumoniae genes associated with hypothiocyanous acid tolerance through genome-wide screening. Journal of Bacteriology. Advance online publication. doi: 10.1128/jb.00208-23

Journal - Research Article

Smith, L. M., Hampton, H. G., Yevstigneyeva, M. S., Mahler, M., Paquet, Z. S. M., & Fineran, P. C. (2023). CRISPR-Cas immunity is repressed by the LysR-type transcriptional regulator PigU. Nucleic Acids Research. Advance online publication. doi: 10.1093/nar/gkad1165

Journal - Research Article

Birkholz, N., Jackson, S. A., Fagerlund, R. D., & Fineran, P. C. (2022). A mobile restriction-modification system provides phage defence and resolves an epigenetic conflict with an antagonistic endonuclease. Nucleic Acids Research, 50(6), 3348-3361. doi: 10.1093/nar/gkac147

Journal - Research Article

Kim, G. E., Lee, S. Y., Birkholz, N., Kamata, K., Jeong, J.-H., Kim, Y.-G., Fineran, P. C., & Park, H. H. (2022). Molecular basis of dual anti-CRISPR and auto-regulatory functions of AcrIF24. Nucleic Acids Research, 50(19), 11344-11358. doi: 10.1093/nar/gkac880

Journal - Research Article

Lee, S. Y., Birkholz, N., Fineran, P. C., & Park, H. H. (2022). Molecular basis of anti-CRISPR operon repression by Aca10. Nucleic Acids Research, 50(15), 8919-8928. doi: 10.1093/nar/gkac656

Journal - Research Article

Malone, L. M., Hampton, H. G., Morgan, X. C., & Fineran, P. C. (2022). Type I CRISPR-Cas provides robust immunity but incomplete attenuation of phage-induced cellular stress. Nucleic Acids Research, 50(1), 160-174. doi: 10.1093/nar/gkab1210

Journal - Research Article

Mayo-Muñoz, D., Smith, L. M., Garcia-Doval, C., Malone, L. M., Harding, K. R., Jackson, S. A., Hampton, H. G., Fagerlund, R. D., Gumy, L. F., & Fineran, P. C. (2022). Type III CRISPR-Cas provides resistance against nucleus-forming jumbo phages via abortive infection. Molecular Cell, 82, 4471-4486.e9. doi: 10.1016/j.molcel.2022.10.028

Journal - Research Article

Payne, L. J., Meaden, S., Mestre, M. R., Palmer, C., Toro, N., Fineran, P. C., & Jackson, S. A. (2022). PADLOC: A web server for the identification of antiviral defence systems in microbial genomes. Nucleic Acids Research, 50, W541-W550. doi: 10.1093/nar/gkac400

Journal - Research Article

Pinilla-Redondo, R., Russell, J., Mayo-Muñoz, D., Shah, S. A., Garrett, R. A., Nesme, J., … Fineran, P. C., & Sørensen, S. J. (2022). CRISPR-Cas systems are widespread accessory elements across bacterial and archaeal plasmids. Nucleic Acids Research, 50(8), 4315-4328. doi: 10.1093/nar/gkab859

Journal - Research Article

Schwartz, E. A., McBride, T. M., Bravo, J. P. K., Wrapp, D., Fineran, P. C., Fagerlund, R. D., & Taylor, D. W. (2022). Structural rearrangements allow nucleic acid discrimination by type I-D Cascade. Nature Communications, 13, 2829. doi: 10.1038/s41467-022-30402-8

Journal - Research Article

Shehreen, S., Birkholz, N., Fineran, P. C., & Brown, C. M. (2022). Widespread repression of anti-CRISPR production by anti-CRISPR-associated proteins. Nucleic Acids Research, 50(15), 8615-8625. doi: 10.1093/nar/gkac674

Journal - Research Article

Warring, S. L., Malone, L. M., Jayaraman, J., Easingwood, R. A., Rigano, L. A., Frampton, R. A., … Kleffmann, T., … Bostina, M., & Fineran, P. C. (2022). A lipopolysaccharide-dependent phage infects a pseudomonad phytopathogen and can evolve to evade phage resistance. Environmental Microbiology, 24(10), 4834-4852. doi: 10.1111/1462-2920.16106

Journal - Research Article

Payne, L. J., Todeschini, T. C., Wu, Y., Perry, B. J., Ronson, C. W., Fineran, P. C., … Jackson, S. A. (2021). Identification and classification of antiviral defence systems in bacteria and archaea with PADLOC reveals new system types. Nucleic Acids Research, 49(19), 10868-10878. doi: 10.1093/nar/gkab883

Journal - Research Article

Rey Campa, A., Smith, L. M., Hampton, H. G., Sharma, S., Jackson, S. A., Bischler, T., … Fineran, P. C. (2021). The Rsm (Csr) post-transcriptional regulatory pathway coordinately controls multiple CRISPR-Cas immune systems. Nucleic Acids Research, 49(16), 9508-9525. doi: 10.1093/nar/gkab704

Journal - Research Article

Sitter, T. L., Vaughan, A. L., Schoof, M., Jackson, S. A., Glare, T. R., Cox, M. P., Fineran, P. C., Gardner, P. P., & Hurst, M. R. H. (2021). Evolution of virulence in a novel family of transmissible mega-plasmids. Environmental Microbiology, 23(9), 5289-5304. doi: 10.1111/1462-2920.15595

Journal - Research Article

Smith, L. M., Jackson, S. A., Malone, L. M., Ussher, J. E., Gardner, P. P., & Fineran, P. C. (2021). The Rcs stress response inversely controls surface and CRISPR–Cas adaptive immunity to discriminate plasmids and phages. Nature Microbiology, 6, 162-172. doi: 10.1038/s41564-020-00822-7

Journal - Research Article

Usher, B., Birkholz, N., Beck, I. N., Fagerlund, R. D., Jackson, S. A., Fineran, P. C., & Blower, T. R. (2021). Crystal structure of the anti-CRISPR repressor Aca2. Journal of Structural Biology, 213, 107752. doi: 10.1016/j.jsb.2021.107752

Journal - Research Article

Beck, I. N., Usher, B., Hampton, H. G., Fineran, P. C., & Blower, T. R. (2020). Antitoxin autoregulation of M. tuberculosis toxin-antitoxin expression through negative cooperativity arising from multiple inverted repeat sequences. Biochemical Journal, 477, 2401-2419. doi: 10.1042/bcj20200368

Journal - Research Article

Cai, Y., Usher, B., Gutierrez, C., Tolcan, A., Mansour, M., Fineran, P. C., … Blower, T. R. (2020). A nucleotidyltransferase toxin inhibits growth of Mycobacterium tuberculosis through inactivation of tRNA acceptor stems. Science Advances, 6(31), eabb6651. doi: 10.1126/sciadv.abb6651

Journal - Research Article

Hampton, H. G., Smith, L. M., Ferguson, S., Meaden, S., Jackson, S. A., & Fineran, P. C. (2020). Functional genomics reveals the toxin-antitoxin repertoire and AbiE activity in Serratia. Microbial Genomics, 6, 1-15. doi: 10.1099/mgen.0.000458

Journal - Research Article

Jayaraman, J., Jones, W. T., Harvey, D., Hemara, L. M., McCann, H. C., Yoon, M., Warring, S. L., Fineran, P. C., … Templeton, M. D. (2020). Variation at the common polysaccharide antigen locus drives lipopolysaccharide diversity within the Pseudomonas syringae species complex. Environmental Microbiology, 22(12), 5356-5372. doi: 10.1111/1462-2920.15250

Journal - Research Article

Malone, L. M., Warring, S. L., Jackson, S. A., Warnecke, C., Gardner, P. P., Gumy, L. F., & Fineran, P. C. (2020). A jumbo phage that forms a nucleus-like structure evades CRISPR-Cas DNA targeting but is vulnerable to type III RNA-based immunity. Nature Microbiology, 5, 48-55. doi: 10.1038/s41564-019-0612-5

Journal - Research Article

McBride, T. M., Schwartz, E. A., Kumar, A., Taylor, D. W., Fineran, P. C., & Fagerlund, R. D. (2020). Diverse CRISPR-Cas complexes require independent translation of small and large subunits from a single gene. Molecular Cell, 80, 971-979. doi: 10.1016/j.molcel.2020.11.003

Journal - Research Article

Pinilla-Redondo, R., Shehreen, S., Marino, N. D., Fagerlund, R. D., Brown, C. M., Sørensen, S. J., Fineran, P. C., & Bondy-Denomy, J. (2020). Discovery of multiple anti-CRISPRs highlights anti-defense gene clustering in mobile genetic elements. Nature Communications, 11(1), 5652. doi: 10.1038/s41467-020-19415-3

Journal - Research Article

Rollie, C., Chevallereau, A., Watson, B. N. J., Chyou, T.-y., Fradet, O., McLeod, I., Fineran, P. C., Brown, C. M., … Westra, E. R. (2020). Targeting of temperate phages drives loss of type I CRISPR-Cas systems. Nature, 578, 149-153. doi: 10.1038/s41586-020-1936-2

Journal - Research Article

Birkholz, N., Fagerlund, R. D., Smith, L. M., Jackson, S. A., & Fineran, P. C. (2019). The autoregulator Aca2 mediates anti-CRISPR repression. Nucleic Acids Research, 47(18), 9658-9665. doi: 10.1093/nar/gkz721

Journal - Research Article

Edwards, R. A., Vega, A. A., Norman, H. M., Ohaeri, M., Levi, K., Dinsdale, E. A., … Fineran, P. C., … Dutilh, B. E. (2019). Global phylogeography and ancient evolution of the widespread human gut virus crAssphage. Nature Microbiology, 4, 1727-1736. doi: 10.1038/s41564-019-0494-6

Journal - Research Article

Fineran, P. C. (2019). CRISPR-Cas impedes archaeal mating. Nature Microbiology, 4(1), 2-3. doi: 10.1038/s41564-018-0326-0

Journal - Research Article

Greisch, J.-F., Tamara, S., Scheltema, R. A., Maxwell, H. W. R., Fagerlund, R. D., Fineran, P. C., … Heck, A. J. R. (2019). Expanding the mass range for UVPD-based native top-down mass spectrometry. Chemical Science, 10, 7163-7171. doi: 10.1039/c9sc01857c

Journal - Research Article

Hampton, H. G., Patterson, A. G., Chang, J. T., Taylor, C., & Fineran, P. C. (2019). GalK limits type I-F CRISPR-Cas expression in a CRP-dependent manner. FEMS Microbiology Letters, 366, fnz137. doi: 10.1093/femsle/fnz137

Journal - Research Article

Jackson, S. A., Birkholz, N., Malone, L. M., & Fineran, P. C. (2019). Imprecise spacer acquisition generates CRISPR-Cas immune diversity through primed adaptation. Cell Host & Microbe, 25, 250-260. doi: 10.1016/j.chom.2018.12.014

Journal - Research Article

Nicholson, T. J., Jackson, S. A., Croft, B. I., Staals, R. H. J., Fineran, P. C., & Brown, C. M. (2019). Bioinformatic evidence of widespread priming in type I and II CRISPR-Cas systems. RNA Biology, 16(4), 566-576. doi: 10.1080/15476286.2018.1509662

Journal - Research Article

Shehreen, S., Chyou, T.-y., Fineran, P. C., & Brown, C. M. (2019). Genome-wide correlation analysis suggests different roles of CRISPR-Cas systems in the acquisition of antibiotic resistance genes in diverse species. Philosophical Transactions of the Royal Society B, 374(1772), 20180384. doi: 10.1098/rstb.2018.0384

Journal - Research Article

Watson, B. N. J., Easingwood, R. A., Tong, B., Wolf, M., Salmond, G. P. C., Staals, R. H. J., Bostina, M., & Fineran, P. C. (2019). Different genetic and morphological outcomes for phages targeted by single or multiple CRISPR-Cas spacers. Philosophical Transactions of the Royal Society B, 374(1772), 20180090. doi: 10.1098/rstb.2018.0090

Journal - Research Article

Watson, B. N. J., Vercoe, R. B., Salmond, G. P. C., Westra, E. R., Staals, R. H. J., & Fineran, P. C. (2019). Type I–F CRISPR-Cas resistance against virulent phages results in abortive infection and provides population-level immunity. Nature Communications, 10, 5526. doi: 10.1038/s41467-019-13445-2

Journal - Research Article

Dy, R. L., Rigano, L. A., & Fineran, P. C. (2018). Phage-based biocontrol strategies and their application in agriculture and aquaculture. Biochemical Society Transactions, 46(4), BST20180178, 1605-1613. doi: 10.1042/bst20180178

Journal - Research Article

Hampton, H. G., Jackson, S. A., Fagerlund, R. D., Vogel, A. I. M., Dy, R. L., Blower, T. R., & Fineran, P. C. (2018). AbiEi binds cooperatively to the Type IV abiE toxin-antitoxin operator via a positively-charged surface and causes DNA bending and negative autoregulation. Journal of Molecular Biology, 430(8), 1141-1156. doi: 10.1016/j.jmb.2018.02.022

Journal - Research Article

Watson, B. N. J., Staals, R. H. J., & Fineran, P. C. (2018). CRISPR-Cas-mediated phage resistance enhances horizontal gene transfer by transduction. mBio, 9(1), e02406-17. doi: 10.1128/mBio.02406-17

Journal - Research Article

Blower, T. R., Chai, R., Przybilski, R., Chindhy, S., Fang, X., Kidman, S. E., … Fineran, P. C., & Salmond, G. P. C. (2017). Evolution of Pectobacterium bacteriophage ΦM1 to escape two bifunctional type III toxin-antitoxin and abortive infection systems through mutations in a single viral gene. Applied & Environmental Microbiology, 83(8), e03229-16. doi: 10.1128/aem.03229-16

Journal - Research Article

Fagerlund, R. D., Wilkinson, M. E., Klykov, O., Barendregt, A., Pearce, F. G., Kieper, S. N., Maxwell, H. W. R., … Krause, K. L., Bostina, M., … Staals, R. H. J., & Fineran, P. C. (2017). Spacer capture and integration by a type I-F Cas1–Cas2-3 CRISPR adaptation complex. PNAS, 114(26), E5122-E5128. doi: 10.1073/pnas.1618421114

Journal - Research Article

Jackson, S. A., McKenzie, R. E., Fagerlund, R. D., Kieper, S. N., Fineran, P. C., & Brouns, S. J. J. (2017). CRISPR-Cas: Adapting to change. Science, 356(6333), eaal5056. doi: 10.1126/science.aal5056

Journal - Research Article

Mesarich, C. H., Rees-George, J., Gardner, P. P., Ghomi, F. A., Gerth, M. L., Andersen, M. T., … Fineran, P. C., & Templeton, M. D. (2017). Transposon insertion libraries for the characterization of mutants from the kiwifruit pathogen Pseudomonas syringae pv. actinidiae. PLoS ONE, 12(3), e0172790. doi: 10.1371/journal.pone.0172790

Journal - Research Article

Patterson, A. G., Yevstigneyeva, M. S., & Fineran, P. C. (2017). Regulation of CRISPR-Cas adaptive immune systems [Review]. Current Opinion in Microbiology, 37(1), 1-7. doi: 10.1016/j.mib.2017.02.004

Journal - Research Article

Silas, S., Lucas-Elio, P., Jackson, S. A., Aroca-Crevillén, A., Hansen, L. L., Fineran, P. C., … Sánchez-Amat, A. (2017). Type III CRISPR-Cas systems can provide redundancy to counteract viral escape from type I systems. eLIFE, 6, e27601. doi: 10.7554/eLife.27601

Journal - Research Article

Biswas, A., Staals, R. H. J., Morales, S. E., Fineran, P. C., & Brown, C. M. (2016). CRISPRDetect: A flexible algorithm to define CRISPR arrays. BMC Genomics, 17, 356. doi: 10.1186/s12864-016-2627-0

Journal - Research Article

Hampton, H. G., McNeil, M. B., Paterson, T. J., Ney, B., Williamson, N. R., Easingwood, R. A., Bostina, M., … Fineran, P. C. (2016). CRISPR-Cas gene-editing reveals RsmA and RsmC act through FlhDC to repress the SdhE flavinylation factor and control motility and prodigiosin production in Serratia. Microbiology, 162(6), 1047-1058. doi: 10.1099/mic.0.000283

Journal - Research Article

Panda, P., Vanga, B. R., Lu, A., Fiers, M., Fineran, P. C., Butler, R., … Ronson, C. W., & Pitman, A. R. (2016). Pectobacterium atrosepticum and Pectobacterium carotovorum harbor distinct, independently acquired integrative and conjugative elements encoding coronafacic acid that enhance virulence on potato stems. Frontiers in Microbiology, 7, 397. doi: 10.3389/fmicb.2016.00397

Journal - Research Article

Patterson, A. G., Jackson, S. A., Taylor, C., Evans, G. B., Salmond, G. P. C., Przybilski, R., Staals, R. H. J., & Fineran, P. C. (2016). Quorum sensing controls adaptive immunity through the regulation of multiple CRISPR-Cas systems. Molecular Cell, 64(6), 1102-1108. doi: 10.1016/j.molcel.2016.11.012

Journal - Research Article

Pawluk, A., Staals, R. H. J., Taylor, C., Watson, B. N. J., Saha, S., Fineran, P. C., … Davidson, A. R. (2016). Inactivation of CRISPR-Cas systems by anti-CRISPR proteins in diverse bacterial species. Nature Microbiology, 1, 16085. doi: 10.1038/nmicrobiol.2016.85

Journal - Research Article

Staals, R. H. J., Jackson, S. A., Biswas, A., Brouns, S. J. J., Brown, C. M., & Fineran, P. C. (2016). Interference-driven spacer acquisition is dominant over naive and primed adaptation in a native CRISPR–Cas system. Nature Communications, 7, 12853. doi: 10.1038/ncomms12853

Journal - Research Article

Wilkinson, M. E., Nakatani, Y., Staals, R. H. J., Kieper, S. N., Opel-Reading, H. K., McKenzie, R. E., Fineran, P. C., & Krause, K. L. (2016). Structural plasticity and in vivo activity of Cas1 from the type I-F CRISPR-Cas system. Biochemical Journal, 473, 1063-1072. doi: 10.1042/bcj20160078

Journal - Research Article

Fagerlund, R. D., Staals, R. H. J., & Fineran, P. C. (2015). The Cpf1 CRISPR-Cas protein expands genome-editing tools. Genome Biology, 16, 251. doi: 10.1186/s13059-015-0824-9

Journal - Research Article

Frampton, R. A., Lopez Acedo, E., Young, V. L., Chen, D., Tong, B., Taylor, C., Easingwood, R. A., … Kleffmann, T., Bostina, M., & Fineran, P. C. (2015). Genome, proteome and structure of a T7-like bacteriophage of the kiwifruit canker phytopathogen Pseudomonas syringae pv. actinidiae. Viruses, 7(7), 3361-3379. doi: 10.3390/v7072776

Journal - Research Article

Holguín Moreno, A. V., Rangel, G., Clavijo, V., Prada, C., Mantilla, M., Gomez, M. C., … Fineran, P. C., … Vives, M. J. (2015). Phage ΦPan70, a putative temperate phage, controls Pseudomonas aeruginosa in planktonic, biofilm and burn mouse model assays. Viruses, 7(8), 4602-4623. doi: 10.3390/v7082835

Journal - Research Article

Patterson, A. G., Chang, J. T., Taylor, C., & Fineran, P. C. (2015). Regulation of the Type I-F CRISPR-Cas system by CRP-cAMP and GalM controls spacer acquisition and interference. Nucleic Acids Research, 43(12), 6038-6048. doi: 10.1093/nar/gkv517

Journal - Research Article

Salmond, G. P. C., & Fineran, P. C. (2015). A century of the phage: Past, present and future. Nature Reviews Microbiology, 777-786. doi: 10.1038/nrmicro3564

Journal - Research Article

Templeton, M. D., Warren, B. A., Anderson, M. T., Rikkerink, E. H. A., & Fineran, P. C. (2015). Complete DNA sequence of Pseudomonas syringae pv. actinidiae, the causal agent of kiwifruit canker disease. Genome Announcements, 3(5), e01054 -e01055 . doi: 10.1128/genomeA.01054-15

Journal - Research Article

Biswas, A., Fineran, P. C., & Brown, C. M. (2014). Accurate computational prediction of the transcribed strand of CRISPR noncoding RNAs. Bioinformatics, 30(13), 1805-1813. doi: 10.1093/bioinformatics/btu114

Journal - Research Article

Dy, R. L., Przybilski, R., Semeijn, K., Salmond, G. P. C., & Fineran, P. C. (2014). A widespread bacteriophage abortive infection system functions through a Type IV toxin-antitoxin mechanism. Nucleic Acids Research, 42(7), 4590-4605. doi: 10.1093/nar/gkt1419

Journal - Research Article

Dy, R. L., Richter, C., Salmond, G. P. C., & Fineran, P. C. (2014). Remarkable mechanisms in microbes to resist phage infections. Annual Review of Virology, 1, 307-331. doi: 10.1146/annurev-virology-031413-085500

Journal - Research Article

Fineran, P. C., & Dy, R. L. (2014). Gene regulation by engineered CRISPR-Cas systems. Current Opinion in Microbiology, 18, 83-89. doi: 10.1016/j.mib.2014.02.007

Journal - Research Article

Fineran, P. C., Gerritzen, M. J. H., Suárez-Diez, M., Künne, T., Boekhorst, J., van Hijum, S. A. F. T., Staals, R. H. J., & Brouns, S. J. J. (2014). Degenerate target sites mediate rapid primed CRISPR adaptation. PNAS, 111(16), E1629-E1638. doi: 10.1073/pnas.1400071111

Journal - Research Article

Frampton, R. A., Taylor, C., Holguín Moreno, A. V., Visnovsky, S. B., Petty, N. K., Pitman, A. R., & Fineran, P. C. (2014). Identification of bacteriophages for the biocontrol of the kiwifruit canker phytopathogen Pseudomonas syringae pv. actinidiae. Applied & Environmental Microbiology, 80(7), 2216-2228. doi: 10.1128/aem.00062-14

Journal - Research Article

McNeil, M. B., Hampton, H. G., Hards, K. J., Watson, B. N. J., Cook, G. M., & Fineran, P. C. (2014). The succinate dehydrogenase assembly factor, SdhE, is required for the flavinylation and activation of fumarate reductase in bacteria. FEBS Letters, 588(3), 414-421. doi: 10.1016/j.febslet.2013.12.019

Journal - Research Article

Richter, C., Dy, R. L., McKenzie, R. E., Watson, B. N. J., Taylor, C., Chang, J. T., McNeil, M. B., Staals, R. H. J., & Fineran, P. C. (2014). Priming in the Type I-F CRISPR-Cas system triggers strand-independent spacer acquisition, bi-directionally from the primed protospacer. Nucleic Acids Research, 42(13), 8516-8526. doi: 10.1093/nar/gku527

Journal - Research Article

Biswas, A., Gagnon, J. N., Brouns, S. J. J., Fineran, P. C., & Brown, C. M. (2013). CRISPRTarget: Bioinformatic prediction and analysis of crRNA targets. RNA Biology, 10(5), 817-827. doi: 10.4161/rna.24046

Journal - Research Article

Cook, G. M., Robson, J. R., Frampton, R. A., McKenzie, J., Przybilski, R., Fineran, P. C., & Arcus, V. L. (2013). Ribonucleases in bacterial toxin–antitoxin systems. Biochimica et Biophysica Acta: Gene Regulatory Mechanisms, 1829, 523-531. doi: 10.1016/j.bbagrm.2013.02.007

Journal - Research Article

Dy, R. L., Pitman, A. R., & Fineran, P. C. (2013). Chromosomal targeting by CRISPR-Cas systems can contribute to genome plasticity in bacteria. Mobile Genetic Elements, 3(5), e26831. doi: 10.4161/mge.26831

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Fineran, P. C., Iglesias Cans, M. C., Ramsay, J. P., Wilf, N. M., Cossyleon, D., McNeil, M. B., … Stanton, J.-A. L., … Salmond, G. P. C. (2013). Draft genome sequence of Serratia sp. strain ATCC 39006, a model bacterium for analysis of the biosynthesis and regulation of prodigiosin, a carbapenem, and gas vesicles. Genome Announcements, 1(6), e01039-13. doi: 10.1128/genomeA.01039-13

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McNeil, M. B., & Fineran, P. C. (2013). Prokaryotic assembly factors for the attachment of flavin to complex II. Biochimica et Biophysica Acta: Bioenergetics, 1827, 637-647. doi: 10.1016/j.bbabio.2012.09.003

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McNeil, M. B., & Fineran, P. C. (2013). The conserved RGxxE motif of the bacterial FAD assembly factor SdhE is required for succinate dehydrogenase flavinylation and activity. Biochemistry, 52, 7628-7640. doi: 10.1021/bi401006a

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McNeil, M. B., Iglesias Cans, M. C., Clulow, J. S., & Fineran, P. C. (2013). YgfX (CptA) is a multimeric membrane protein that interacts with the succinate dehydrogenase assembly factor SdhE (YgfY). Microbiology, 159, 1352-1365. doi: 10.1099/mic.0.068510-0

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Richter, C., & Fineran, P. C. (2013). The subtype I-F CRISPR-Cas system influences pathogenicity island retention in Pectobacterium atrosepticum via crRNA generation and Csy complex formation. Biochemical Society Transactions, 41(6), 1468-1474. doi: 10.1042/bst20130151

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Sangal, V., Fineran, P. C., & Hoskisson, P. A. (2013). Novel configurations of type I and II CRISPR-Cas systems in Corynebacterium diphtheriae. Microbiology, 159(Pt 10), 2118-2126. doi: 10.1099/mic.0.070235-0

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Short, F. L., Pei, X. Y., Blower, T. R., Ong, S.-L., Fineran, P. C., Luisi, B. F., & Salmond, G. P. C. (2013). Selectivity and self-assembly in the control of a bacterial toxin by an antitoxic noncoding RNA pseudoknot. PNAS, 110(3), 820-821. doi: 10.1073/pnas.1216039110

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Vercoe, R. B., Chang, J. T., Dy, R. L., Taylor, C., Gristwood, T., Clulow, J. S., Richter, C., Przybilski, R., … Fineran, P. C. (2013). Cytotoxic chromosomal targeting by CRISPR/Cas systems can reshape bacterial genomes and expel or remodel pathogenicity islands. PLoS Genetics, 9(4), e1003454. doi: 10.1371/journal.pgen.1003454

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Westra, E. R., Staals, R. H. J., Gort, G., Høgh, S., Neumann, S., de la Cruz, F., Fineran, P. C., & Brouns, S. J. J. (2013). CRISPR-Cas systems preferentially target the leading regions of MOB_F conjugative plasmids. RNA Biology, 10(5), 749-761. doi: 10.4161/rna.24202

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Blower, T. R., Evans, T. J., Przybilski, R., Fineran, P. C., & Salmond, G. P. C. (2012). Viral evasion of a bacterial suicide system by RNA–based molecular mimicry enables infectious altruism. PLoS Genetics, 8(10), e1003023. doi: 10.1371/journal.pgen.1003023

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Blower, T. R., Short, F. L., Fineran, P. C., & Salmond, G. P. C. (2012). Viral molecular mimicry circumvents abortive infection and suppresses bacterial suicide to make hosts permissive for replication. Bacteriophage, 2(4), 234-238. doi: 10.4161/bact.23830

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Blower, T. R., Short, F. L., Rao, F., Mizuguchi, K., Pei, X. Y., Fineran, P. C., … Salmond, G. P. C. (2012). Identification and classification of bacterial Type III toxin-antitoxin systems encoded in chromosomal and plasmid genomes. Nucleic Acids Research, 40(13), 6158-6173. doi: 10.1093/nar/gks231

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Fineran, P. C., & Charpentier, E. (2012). Memory of viral infections by CRISPR-Cas adaptive immune systems: Acquisition of new information. Virology, 434, 202-209. doi: 10.1016/j.virol.2012.10.003

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Frampton, R. A., Pitman, A. R., & Fineran, P. C. (2012). Advances in bacteriophage-mediated control of plant pathogens. International Journal of Microbiology, 2012, 326452. doi: 10.1155/2012/326452

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McNeil, M. B., Clulow, J. S., Wilf, N. M., Salmond, G. P. C., & Fineran, P. C. (2012). SdhE is a conserved protein required for the flavinylation of succinate dehydrogenase in bacteria. Journal of Biological Chemistry, 287(22), 18418-18428. doi: 10.1074/jbc.M111.293803

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Richter, C., Chang, J. T., & Fineran, P. C. (2012). Function and regulation of clustered regularly interspaced short palindromic repeats (CRISPR) / CRISPR associated (Cas) systems. Viruses, 4(10), 2291-2311. doi: 10.3390/v4102291

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Richter, C., Gristwood, T., Clulow, J. S., & Fineran, P. C. (2012). In vivo protein interactions and complex formation in the Pectobacterium atrosepticum subtype I-F CRISPR/Cas system. PLoS ONE, 7(12), e49549. doi: 10.1371/journal.pone.0049549

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Blower, T. R., Pei, X. Y., Short, F. L., Fineran, P. C., Humphreys, D. P., Luisi, B. F., & Salmond, G. P. C. (2011). A processed noncoding RNA regulates an altruistic bacterial antiviral system. Nature Structural & Molecular Biology, 18(2), 185-191. doi: 10.1038/nsmb.1981

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Gristwood, T., McNeil, M. B., Clulow, J. S., Salmond, G. P. C., & Fineran, P. C. (2011). PigS and PigP regulate prodigiosin biosynthesis in Serratia via differential control of divergent operons, which include predicted transporters of sulfur-containing molecules. Journal of Bacteriology, 193(5), 1076-1085. doi: 10.1128/JB.00352-10

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Przybilski, R., Richter, C., Gristwood, T., Clulow, J. S., Vercoe, R. B., & Fineran, P. C. (2011). Csy4 is responsible for CRISPR RNA processing in Pectobacterium atrosepticum. RNA Biology, 8(3), 517-528. doi: 10.4161/rna.8.3.15190

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