Dr Sarah Baird

2023

Journal - Research Article

Barzegar-Fallah, A., Alimoradi, H., Dunlop, J. L., Torbati, E., & Baird, S. K. (2023). Serotonin type-3 receptor antagonists selectively kill melanoma cells through classical apoptosis, microtubule depolymerisation, ERK activation, and NF-κB downregulation. Cell Biology & Toxicology, 39, 1119-1135. doi: 10.1007/s10565-021-09667-0

2022

Conference Contribution - Verbal presentation and other Conference outputs

Petersen, J. S. S. M., & Baird, S. K. (2022, August). Anti-helmintic drugs mebendazole and albendazole cause selective apoptotic cell death in colorectal and breast cancer cell lines. Verbal presentation at the Cancer Satellite Meeting: Queenstown Research Week, Queenstown, New Zealand.

2021

Journal - Research Article

Clarke, M. R., Jones, B., Squires, C. M. L., Imhoff, F. M., Harwood, D. T., Rhodes, L., … Baird, S. K. (2021). Cyclic imine pinnatoxin G is cytotoxic to cancer cell lines via nicotinic acetylcholine receptor-driven classical apoptosis. Journal of Natural Products, 84 , 2035-2042. doi: 10.1021/acs.jnatprod.1c00418

Petersen, J. S. S. M., & Baird, S. K. (2021). Treatment of breast and colon cancer cell lines with anti-helmintic benzimidazoles mebendazole or albendazole results in selective apoptotic cell death. Journal of Cancer Research & Clinical Oncology, 147, 2945-2953. doi: 10.1007/s00432-021-03698-0

2020

Journal - Research Other

Rai, G. P., & Baird, S. K. (2020). Tissue inhibitor of matrix metalloproteinase-3 has both anti-metastatic and anti-tumourigenic properties. Clinical & Experimental Metastasis, 37, 69-76. doi: 10.1007/s10585-019-10017-y

2019

Journal - Research Article

Vangala, G., Imhoff, F. M., Squires, C. M. L., Cridge, A. G., & Baird, S. K. (2019). Mesenchymal stem cell homing towards cancer cells is increased by enzyme activity of cathepsin D. Experimental Cell Research, 383, 111494. doi: 10.1016/j.yexcr.2019.07.007

2018

Journal - Research Article

Abel, S. D. A., Dadhwal, S., Gamble, A. B., & Baird, S. K. (2018). Honey reduces the metastatic characteristics of prostate cancer cell lines by promoting a loss of adhesion. PeerJ, 6, e5115. doi: 10.7717/peerj.5115

Abel, S. D. A., & Baird, S. K. (2018). Honey is cytotoxic towards prostate cancer cells but interacts with the MTT reagent: Considerations for the choice of cell viability assay. Food Chemistry, 241, 70-78. doi: 10.1016/j.foodchem.2017.08.083

Conference Contribution - Published proceedings: Abstract

Barzegar Fallah, A., Alimoradi, H., & Baird, S. K. (2018). 5HT3 receptor antagonists selectively kill melanoma cells. Annals of Oncology, 29(Suppl. 9), (pp. ix107). doi: 10.1093/annonc/mdy439.009

Vangala, G., Imhoff, F. M., Clarke, M. R., Squires, C. M. L., & Baird, S. K. (2018). Mesenchymal stem cells in tumour development: How do they home to tumour sites and how do they affect tumour progression? Proceedings of the New Zealand Society for Oncology (NZSO) Conference. Retrieved from http://www.nzsoncology.org.nz/

Conference Contribution - Poster Presentation (not in published proceedings)

Badart, M. P., Lamb, R. A., Swaney, B. E., Gai, S., Squires, C. M. L., Baird, S. K., & Hawkins, B. C. (2018, August). Synthesis of bioactive natural products. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

Vangala, G., Cridge, A., & Baird, S. (2018, August). Cathepsin D: A protease attracts mesenchymal stem cells for homing to tumor sites. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

Other Research Output

Baird, S. (2018, March). Research overview: From bees to bazookas and back again. Department of Pharmacology & Toxicology, University of Otago, Dunedin, New Zealand. [Department Seminar].

2016

Journal - Research Article

Badart, M. P., Squires, C. M. L., Baird, S. K., & Hawkins, B. C. (2016). The synthesis of clavatadine C. Tetrahedron Letters, 57(46), 5108-5111. doi: 10.1016/j.tetlet.2016.10.019

Conference Contribution - Published proceedings: Abstract

Petersen, J., Lamb, R. A., Badart, M. P., Hawkins, B. C., & Baird, S. K. (2016). Anticancer effects of novel 4-substituted phenylthiazoles derived from marine actinomycetes. Proceedings of the Diagnostics, Drugs, Devices, Discovery (D4) Conference. Retrieved from http://www.otago.ac.nz/d4/index.html

2015

Journal - Research Article

Lamb, R. A., Badart, M. P., Swaney, B. E., Gai, S., Baird, S. K., & Hawkins, B. C. (2015). The synthesis and biological evaluation of anithiactin A/thiasporine C and analogues. Australian Journal of Chemistry, 68(12), 1829-1833. doi: 10.1071/CH15461

Baird, S. K., Rigopoulos, A., Cao, D., Allan, L., Renner, C., Scott, F. E., & Scott, A. M. (2015). Integral membrane protease fibroblast activation protein sensitizes fibrosarcoma to chemotherapy and alters cell death mechanisms. Apoptosis, 20(11), 1483-1498. doi: 10.1007/s10495-015-1166-5

Lei, J., Burgess, E. J., Richardson, A. T. B., Hawkins, B. C., Baird, S. K., Smallfield, B. M., van Klink, J. W., & Perry, N. B. (2015). Cytotoxic amides from fruits of kawakawa, Macropiper excelsum. Planta Medica, 81, 1163-1168. doi: 10.1055/s-0035-1546106

Baird, S. K., Allan, L., Renner, C., Scott, F. E., & Scott, A. M. (2015). Fibroblast activation protein increases metastatic potential of fibrosarcoma line HT1080 through upregulation of integrin-mediated signaling pathways. Clinical & Experimental Metastasis, 32(5), 507-516. doi: 10.1007/s10585-015-9723-4

Baird, S. K. (2015). Mesenchymal stem cells: How can we realize their therapeutic potential in cancer therapy? Journal of Clinical & Experimental Pathology, 5(1), 206. doi: 10.4172/2161-0681.1000206

Clarke, M. R., Imhoff, F. M., & Baird, S. K. (2015). Mesenchymal stem cells inhibit breast cancer cell migration and invasion through secretion of tissue inhibitor of metalloproteinase-1 and -2. Molecular Carcinogenesis, 54(10), 1214-1219. doi: 10.1002/mc.22178

2014

Journal - Research Article

Baird, S. (2014). Mesenchymal stem cells in cancer therapy: Our chance to take charge. European Pharmaceutical Review, 19(2), 55-59.

Conference Contribution - Verbal presentation and other Conference outputs

Imhoff, F. M., Clarke, M. R., Squires, C., & Baird, S. K. (2014, August). Mesenchymal stem cells in tumour development and metastasis. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

2012

Conference Contribution - Poster Presentation (not in published proceedings)

Imhoff, F. M., Squires, C., Clarke, M., & Baird, S. K. (2012, August). Cathespin D has a pivotal role in tumour stroma development. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

2010

Journal - Research Article

Ingemarsdotter, C. K., Baird, S. K., Connell, C. M., Öberg, D., Halldén, G., & McNeish, I. A. (2010). Low-dose paclitaxel synergizes with oncolytic adenoviruses via mitotic slippage and apoptosis in ovarian cancer. Oncogene, 29, 6051-6063. doi: 10.1038/onc.2010.335

Vervoort, L., Burvenich, I., Staelens, S., Dumolyn, C., Waegemans, E., Van Steenkiste, M., Baird, S. K., … De Vos, F. (2010). Preclinical evaluation of monoclonal antibody 14C5 for targeting pancreatic cancer. Cancer Biotherapy & Radiopharmaceuticals, 25(2), 193-205. doi: 10.1089/cbr.2009.0696

Conference Contribution - Verbal presentation and other Conference outputs

Baird, S. K., Renner, C., Smyth, F. E., & Scott, A. M. (2010, February). Cancer-associated fibroblast expression of serine protease fibroblast activation protein increases tumour metastatic potential through integrin-mediated signaling pathways. Verbal presentation at the 22^nd Lorne Cancer Conference, Lorne, Australia.

2009

Conference Contribution - Published proceedings: Abstract

Baird, S. K., Renner, C., Smyth, F. E., & Scott, A. M. (2009). Cancer-associated fibroblast expression of serine protease fibroblast activation protein increases tumour metastatic potential and alters cell death mechanisms. Proceedings of the ComBio Conference. Retrieved from http://www.canterbury.ac.nz/conference/combio09/index.shtml

Conference Contribution - Verbal presentation and other Conference outputs

Baird, S. K., Renner, C., Smyth, F. E., & Scott, A. M. (2009, November). Cancer-associated fibroblast expression of serine protease fibroblast activation protein increases metastatic potential and alters cell death mechanisms. Verbal presentation at the Ludwig Institute for Cancer Research (LICR) Translational Oncology Conference, Melbourne, Australia.

Baird, S. K., Renner, C., Smyth, F. E., & Scott, A. M. (2009, February). Cancer-associated fibroblast expression of serine protease fibroblast activation protein alters cell death mechanisms and increases tumour metastatic potential. Verbal presentation at the 21^st Lorne Cancer Conference, Lorne, Australia.

2008

Journal - Research Article

Firth, C. A., Laing, A. D., Baird, S. K., Pearson, J., & Gieseg, S. P. (2008). Inflammatory sites as a source of plasma neopterin: Measurement of high levels of neopterin and markers of oxidative stress in pus drained from human abscesses. Clinical Biochemistry, 41(13), 1078-1083. doi: 10.1016/j.clinbiochem.2008.06.008

Baird, S. K., Aerts, J. L., Eddaoudi, A., Lockley, M., Lemoine, N. R., & McNeish, I. A. (2008). Oncolytic adenoviral mutants induce a novel mode of programmed cell death in ovarian cancer. Oncogene, 27(22), 3081-3090. doi: 10.1038/sj.onc.1210977

Conference Contribution - Published proceedings: Abstract

Baird, S. K., Ingemarsdotter, C. K., Eddaoudi, A., Lockley, M., Lemoine, N. R., & McNeish, I. A. (2008). Oncolytic adenoviral mutants define a novel mode of programmed cell death in ovarian cancer. Human Gene Therapy, 19(4), (pp. 399). doi: 10.1089/hum.2008.1326

2006

Journal - Research Article

Larsson, D. A., Baird, S., Nyhalah, J. D., Yuan, X.-M., & Li, W. (2006). Oxysterol mixtures, in atheroma-relevant proportions, display synergistic and proapoptotic effects. Free Radical Biology & Medicine, 41(6), 902-910. doi: 10.1016/j.freeradbiomed.2006.05.032

Leyton, J., Lockley, M., Aerts, J. L., Baird, S. K., Aboagye, E. O., Lemoine, N. R., & McNeish, I. A. (2006). Quantifying the activity of adenoviral E1A CR2 deletion mutants using Renilla luciferase bioluminescence and 3’-deoxy-3’[¹⁸F]fluorothymidine positron emission tomography imaging. Cancer Research, 66(18), 9178-9185. doi: 10.1158/0008-5472.CAN-06-1539

Baird, S. K., Kurz, T., & Brunk, U. T. (2006). Metallothionein protects against oxidative stress-induced lysosomal destabilization. Biochemical Journal, 394(Part 1), 275-283. doi: 10.1042/BJ20051143

Conference Contribution - Published proceedings: Abstract

Baird, S. K., Lockley, M., Leyton, J., Aboagye, E. O., Lemoine, N. R., & McNeish, I. A. (2006). E1A CR2 deletion mutant adenoviral vectors in ovarian cancer: combination with apoptosis inducers and monitoring with [18F] FLT-PET imaging. Proceedings of the American Association of Cancer Research (AACR). 47. Retrieved from http://www.aacrmeetingabstracts.org/

Baird, S. K., Aerts, J. L., Lemoine, N. R., & McNeish, I. A. (2006). Mechanisms of cell death induced by adenoviral E1A deletion mutants in ovarian cancer. Proceedings of the 14^th European Cell Death Organization (ECDO) Euroconference on Apoptosis. P-19. Retrieved from http://www.ecdo.eu/

2005

Journal - Research Article

Baird, S. K., Reid, L., Hampton, M. B., & Gieseg, S. P. (2005). OxLDL induced cell death is inhibited by the macrophage synthesised pterin, 7,8-dihydroneopterin, in U937 cells but not THP-1 cells. Biochimica et Biophysica Acta: Molecular Cell Reserch, 1745, 361-369. doi: 10.1016/j.bbamcr.2005.07.001

2004

Journal - Research Article

Baird, S. K., Hampton, M. B., & Gieseg, S. P. (2004). Oxidized LDL triggers phosphatidylserine exposure in human monocyte cell lines by both caspase-dependent and -independent mechanisms. FEBS Letters, 578, 169-174.