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Health Sciences profile

Professor Peter Fineran

PositionProfessor
DepartmentDepartment of Microbiology and Immunology
QualificationsBSc (Hons) PhD
Research summaryMolecular microbiology and bacteriophages

Research

Our research goal is to understand the interactions between mobile genetic elements, such as bacteriophages and plasmids, and their bacterial hosts. Our main interest is in phage resistance mechanisms.

Publications

Fagerlund, R. D., Ferguson, T. J., Maxwell, H. W. R., Opel-Reading, H. K., Krause, K. L., & Fineran, P. C. (2019). Reconstitution of CRISPR adaptation in vitro and its detection by PCR. In S. Bailey (Ed.), Methods in enzymology (Vol. 616: CRISPR-Cas enzymes). (pp. 411-433). Cambridge, MA: Academic Press. doi: 10.1016/bs.mie.2018.10.024

Watson, B. N. J., Vercoe, R. B., Salmond, G. P. C., Westra, E. R., Staals, R. H. J., & Fineran, P. C. (2019). Type I–F CRISPR-Cas resistance against virulent phages results in abortive infection and provides population-level immunity. Nature Communications, 10, 5526. doi: 10.1038/s41467-019-13445-2

Shehreen, S., Chyou, T.-y., Fineran, P. C., & Brown, C. M. (2019). Genome-wide correlation analysis suggests different roles of CRISPR-Cas systems in the acquisition of antibiotic resistance genes in diverse species. Philosophical Transactions of the Royal Society B, 374(1772), 20180384. doi: 10.1098/rstb.2018.0384

Birkholz, N., Fagerlund, R. D., Smith, L. M., Jackson, S. A., & Fineran, P. C. (2019). The autoregulator Aca2 mediates anti-CRISPR repression. Nucleic Acids Research. Advance online publication. doi: 10.1093/nar/gkz721

Malone, L. M., Warring, S. L., Jackson, S. A., Warnecke, C., Gardner, P. P., Gumy, L. F., & Fineran, P. C. (2019). A jumbo phage that forms a nucleus-like structure evades CRISPR-Cas DNA targeting but is vulnerable to type III RNA-based immunity. Nature Microbiology. Advance online publication. doi: 10.1038/s41564-019-0612-5

Edited Book - Research

Lundgren, M., Charpentier, E., & Fineran, P. C. (Eds.). (2015). CRISPR: Methods and protocols: Methods in molecular biology (Vol. 1311). Humana Press, 366p. doi: 10.1007/978-1-4939-2687-9

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Chapter in Book - Research

Fagerlund, R. D., Ferguson, T. J., Maxwell, H. W. R., Opel-Reading, H. K., Krause, K. L., & Fineran, P. C. (2019). Reconstitution of CRISPR adaptation in vitro and its detection by PCR. In S. Bailey (Ed.), Methods in enzymology (Vol. 616: CRISPR-Cas enzymes). (pp. 411-433). Cambridge, MA: Academic Press. doi: 10.1016/bs.mie.2018.10.024

Biswas, A., Fineran, P. C., & Brown, C. M. (2015). Computational detection of CRISPR/crRNA targets. In M. Lundgren, E. Charpentier & P. C. Fineran (Eds.), CRISPR: Methods in molecular biology (Vol. 1311). (pp. 77-89). New York, NY: Humana Press. doi: 10.1007/978-1-4939-2687-9_5

Fineran, P. C., Petty, N. K., & Salmond, G. P. C. (2009). Transduction: Host DNA transfer by bacteriophages. In M. Schaechter (Ed.), Encyclopedia of microbiology (Vol. 3). (3rd ed.) (pp. 666-679). Oxford, UK: Elsevier.

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Journal - Research Article

Watson, B. N. J., Vercoe, R. B., Salmond, G. P. C., Westra, E. R., Staals, R. H. J., & Fineran, P. C. (2019). Type I–F CRISPR-Cas resistance against virulent phages results in abortive infection and provides population-level immunity. Nature Communications, 10, 5526. doi: 10.1038/s41467-019-13445-2

Birkholz, N., Fagerlund, R. D., Smith, L. M., Jackson, S. A., & Fineran, P. C. (2019). The autoregulator Aca2 mediates anti-CRISPR repression. Nucleic Acids Research. Advance online publication. doi: 10.1093/nar/gkz721

Malone, L. M., Warring, S. L., Jackson, S. A., Warnecke, C., Gardner, P. P., Gumy, L. F., & Fineran, P. C. (2019). A jumbo phage that forms a nucleus-like structure evades CRISPR-Cas DNA targeting but is vulnerable to type III RNA-based immunity. Nature Microbiology. Advance online publication. doi: 10.1038/s41564-019-0612-5

Shehreen, S., Chyou, T.-y., Fineran, P. C., & Brown, C. M. (2019). Genome-wide correlation analysis suggests different roles of CRISPR-Cas systems in the acquisition of antibiotic resistance genes in diverse species. Philosophical Transactions of the Royal Society B, 374(1772), 20180384. doi: 10.1098/rstb.2018.0384

Edwards, R. A., Vega, A. A., Norman, H. M., Ohaeri, M., Levi, K., Dinsdale, E. A., … Fineran, P. C., … Dutilh, B. E. (2019). Global phylogeography and ancient evolution of the widespread human gut virus crAssphage. Nature Microbiology. Advance online publication. doi: 10.1038/s41564-019-0494-6

Hampton, H. G., Patterson, A. G., Chang, J. T., Taylor, C., & Fineran, P. C. (2019). GalK limits type I-F CRISPR-Cas expression in a CRP-dependent manner. FEMS Microbiology Letters. Advance online publication. doi: 10.1093/femsle/fnz137

Jackson, S. A., Birkholz, N., Malone, L. M., & Fineran, P. C. (2019). Imprecise spacer acquisition generates CRISPR-Cas immune diversity through primed adaptation. Cell Host & Microbe. Advance online publication. doi: 10.1016/j.chom.2018.12.014

Watson, B. N. J., Easingwood, R. A., Tong, B., Wolf, M., Salmond, G. P. C., Staals, R. H. J., Bostina, M., & Fineran, P. C. (2019). Different genetic and morphological outcomes for phages targeted by single or multiple CRISPR-Cas spacers. Philosophical Transactions of the Royal Society B, 374(1772), 20180090. doi: 10.1098/rstb.2018.0090

Fineran, P. C. (2019). CRISPR-Cas impedes archaeal mating. Nature Microbiology, 4(1), 2-3. doi: 10.1038/s41564-018-0326-0

Hampton, H. G., Jackson, S. A., Fagerlund, R. D., Vogel, A. I. M., Dy, R. L., Blower, T. R., & Fineran, P. C. (2018). AbiEi binds cooperatively to the Type IV abiE toxin-antitoxin operator via a positively-charged surface and causes DNA bending and negative autoregulation. Journal of Molecular Biology, 430(8), 1141-1156. doi: 10.1016/j.jmb.2018.02.022

Nicholson, T. J., Jackson, S. A., Croft, B. I., Staals, R. H. J., Fineran, P. C., & Brown, C. M. (2018). Bioinformatic evidence of widespread priming in Type I and II CRISPR-Cas systems. RNA Biology. Advance online publication. doi: 10.1080/15476286.2018.1509662

Dy, R. L., Rigano, L. A., & Fineran, P. C. (2018). Phage-based biocontrol strategies and their application in agriculture and aquaculture. Biochemical Society Transactions, 46(4), BST20180178, 1605-1613. doi: 10.1042/bst20180178

Watson, B. N. J., Staals, R. H. J., & Fineran, P. C. (2018). CRISPR-Cas-mediated phage resistance enhances horizontal gene transfer by transduction. mBio, 9(1), e02406-17. doi: 10.1128/mBio.02406-17

Fagerlund, R. D., Wilkinson, M. E., Klykov, O., Barendregt, A., Pearce, F. G., Kieper, S. N., Maxwell, H. W. R., … Krause, K. L., Bostina, M., … Staals, R. H. J., & Fineran, P. C. (2017). Spacer capture and integration by a type I-F Cas1–Cas2-3 CRISPR adaptation complex. PNAS, 114(26), E5122-E5128. doi: 10.1073/pnas.1618421114

Blower, T. R., Chai, R., Przybilski, R., Chindhy, S., Fang, X., Kidman, S. E., … Fineran, P. C., & Salmond, G. P. C. (2017). Evolution of Pectobacterium bacteriophage ΦM1 to escape two bifunctional type III toxin-antitoxin and abortive infection systems through mutations in a single viral gene. Applied & Environmental Microbiology, 83(8), e03229-16. doi: 10.1128/aem.03229-16

Mesarich, C. H., Rees-George, J., Gardner, P. P., Ghomi, F. A., Gerth, M. L., Andersen, M. T., … Fineran, P. C., & Templeton, M. D. (2017). Transposon insertion libraries for the characterization of mutants from the kiwifruit pathogen Pseudomonas syringae pv. actinidiae. PLoS ONE, 12(3), e0172790. doi: 10.1371/journal.pone.0172790

Silas, S., Lucas-Elio, P., Jackson, S. A., Aroca-Crevillén, A., Hansen, L. L., Fineran, P. C., … Sánchez-Amat, A. (2017). Type III CRISPR-Cas systems can provide redundancy to counteract viral escape from type I systems. eLIFE, 6, e27601. doi: 10.7554/eLife.27601

Jackson, S. A., McKenzie, R. E., Fagerlund, R. D., Kieper, S. N., Fineran, P. C., & Brouns, S. J. J. (2017). CRISPR-Cas: Adapting to change. Science, 356(6333), eaal5056. doi: 10.1126/science.aal5056

Pawluk, A., Staals, R. H. J., Taylor, C., Watson, B. N. J., Saha, S., Fineran, P. C., … Davidson, A. R. (2016). Inactivation of CRISPR-Cas systems by anti-CRISPR proteins in diverse bacterial species. Nature Microbiology, 1, 16085. doi: 10.1038/nmicrobiol.2016.85

Panda, P., Vanga, B. R., Lu, A., Fiers, M., Fineran, P. C., Butler, R., … Ronson, C. W., & Pitman, A. R. (2016). Pectobacterium atrosepticum and Pectobacterium carotovorum harbor distinct, independently acquired integrative and conjugative elements encoding coronafacic acid that enhance virulence on potato stems. Frontiers in Microbiology, 7, 397. doi: 10.3389/fmicb.2016.00397

Biswas, A., Staals, R. H. J., Morales, S. E., Fineran, P. C., & Brown, C. M. (2016). CRISPRDetect: A flexible algorithm to define CRISPR arrays. BMC Genomics, 17, 356. doi: 10.1186/s12864-016-2627-0

Wilkinson, M. E., Nakatani, Y., Staals, R. H. J., Kieper, S. N., Opel-Reading, H. K., McKenzie, R. E., Fineran, P. C., & Krause, K. L. (2016). Structural plasticity and in vivo activity of Cas1 from the type I-F CRISPR-Cas system. Biochemical Journal, 473, 1063-1072. doi: 10.1042/bcj20160078

Staals, R. H. J., Jackson, S. A., Biswas, A., Brouns, S. J. J., Brown, C. M., & Fineran, P. C. (2016). Interference-driven spacer acquisition is dominant over naive and primed adaptation in a native CRISPR–Cas system. Nature Communications, 7, 12853. doi: 10.1038/ncomms12853

Patterson, A. G., Jackson, S. A., Taylor, C., Evans, G. B., Salmond, G. P. C., Przybilski, R., Staals, R. H. J., & Fineran, P. C. (2016). Quorum sensing controls adaptive immunity through the regulation of multiple CRISPR-Cas systems. Molecular Cell, 64(6), 1102-1108. doi: 10.1016/j.molcel.2016.11.012

Hampton, H. G., McNeil, M. B., Paterson, T. J., Ney, B., Williamson, N. R., Easingwood, R. A., Bostina, M., … Fineran, P. C. (2016). CRISPR-Cas gene-editing reveals RsmA and RsmC act through FlhDC to repress the SdhE flavinylation factor and control motility and prodigiosin production in Serratia. Microbiology, 162(6), 1047-1058. doi: 10.1099/mic.0.000283

Frampton, R. A., Lopez Acedo, E., Young, V. L., Chen, D., Tong, B., Taylor, C., Easingwood, R. A., … Kleffmann, T., Bostina, M., & Fineran, P. C. (2015). Genome, proteome and structure of a T7-like bacteriophage of the kiwifruit canker phytopathogen Pseudomonas syringae pv. actinidiae. Viruses, 7(7), 3361-3379. doi: 10.3390/v7072776

Fagerlund, R. D., Staals, R. H. J., & Fineran, P. C. (2015). The Cpf1 CRISPR-Cas protein expands genome-editing tools. Genome Biology, 16, 251. doi: 10.1186/s13059-015-0824-9

Salmond, G. P. C., & Fineran, P. C. (2015). A century of the phage: Past, present and future. Nature Reviews Microbiology, 777-786. doi: 10.1038/nrmicro3564

Templeton, M. D., Warren, B. A., Anderson, M. T., Rikkerink, E. H. A., & Fineran, P. C. (2015). Complete DNA sequence of Pseudomonas syringae pv. actinidiae, the causal agent of kiwifruit canker disease. Genome Announcements, 3(5), e01054 -e01055 . doi: 10.1128/genomeA.01054-15

Patterson, A. G., Chang, J. T., Taylor, C., & Fineran, P. C. (2015). Regulation of the Type I-F CRISPR-Cas system by CRP-cAMP and GalM controls spacer acquisition and interference. Nucleic Acids Research, 43(12), 6038-6048. doi: 10.1093/nar/gkv517

Holguín Moreno, A. V., Rangel, G., Clavijo, V., Prada, C., Mantilla, M., Gomez, M. C., … Fineran, P. C., … Vives, M. J. (2015). Phage ΦPan70, a putative temperate phage, controls Pseudomonas aeruginosa in planktonic, biofilm and burn mouse model assays. Viruses, 7(8), 4602-4623. doi: 10.3390/v7082835

Dy, R. L., Przybilski, R., Semeijn, K., Salmond, G. P. C., & Fineran, P. C. (2014). A widespread bacteriophage abortive infection system functions through a Type IV toxin-antitoxin mechanism. Nucleic Acids Research, 42(7), 4590-4605. doi: 10.1093/nar/gkt1419

Frampton, R. A., Taylor, C., Holguín Moreno, A. V., Visnovsky, S. B., Petty, N. K., Pitman, A. R., & Fineran, P. C. (2014). Identification of bacteriophages for the biocontrol of the kiwifruit canker phytopathogen Pseudomonas syringae pv. actinidiae. Applied & Environmental Microbiology, 80(7), 2216-2228. doi: 10.1128/aem.00062-14

Fineran, P. C., Gerritzen, M. J. H., Suárez-Diez, M., Künne, T., Boekhorst, J., van Hijum, S. A. F. T., Staals, R. H. J., & Brouns, S. J. J. (2014). Degenerate target sites mediate rapid primed CRISPR adaptation. PNAS, 111(16), E1629-E1638. doi: 10.1073/pnas.1400071111

Fineran, P. C., & Dy, R. L. (2014). Gene regulation by engineered CRISPR-Cas systems. Current Opinion in Microbiology, 18, 83-89. doi: 10.1016/j.mib.2014.02.007

Biswas, A., Fineran, P. C., & Brown, C. M. (2014). Accurate computational prediction of the transcribed strand of CRISPR noncoding RNAs. Bioinformatics, 30(13), 1805-1813. doi: 10.1093/bioinformatics/btu114

Dy, R. L., Richter, C., Salmond, G. P. C., & Fineran, P. C. (2014). Remarkable mechanisms in microbes to resist phage infections. Annual Review of Virology, 1, 307-331. doi: 10.1146/annurev-virology-031413-085500

McNeil, M. B., Hampton, H. G., Hards, K. J., Watson, B. N. J., Cook, G. M., & Fineran, P. C. (2014). The succinate dehydrogenase assembly factor, SdhE, is required for the flavinylation and activation of fumarate reductase in bacteria. FEBS Letters, 588(3), 414-421. doi: 10.1016/j.febslet.2013.12.019

Richter, C., Dy, R. L., McKenzie, R. E., Watson, B. N. J., Taylor, C., Chang, J. T., McNeil, M. B., Staals, R. H. J., & Fineran, P. C. (2014). Priming in the Type I-F CRISPR-Cas system triggers strand-independent spacer acquisition, bi-directionally from the primed protospacer. Nucleic Acids Research, 42(13), 8516-8526. doi: 10.1093/nar/gku527

McNeil, M. B., Iglesias Cans, M. C., Clulow, J. S., & Fineran, P. C. (2013). YgfX (CptA) is a multimeric membrane protein that interacts with the succinate dehydrogenase assembly factor SdhE (YgfY). Microbiology, 159, 1352-1365. doi: 10.1099/mic.0.068510-0

Vercoe, R. B., Chang, J. T., Dy, R. L., Taylor, C., Gristwood, T., Clulow, J. S., Richter, C., Przybilski, R., … Fineran, P. C. (2013). Cytotoxic chromosomal targeting by CRISPR/Cas systems can reshape bacterial genomes and expel or remodel pathogenicity islands. PLoS Genetics, 9(4), e1003454. doi: 10.1371/journal.pgen.1003454

Richter, C., & Fineran, P. C. (2013). The subtype I-F CRISPR-Cas system influences pathogenicity island retention in Pectobacterium atrosepticum via crRNA generation and Csy complex formation. Biochemical Society Transactions, 41(6), 1468-1474. doi: 10.1042/bst20130151

McNeil, M. B., & Fineran, P. C. (2013). Prokaryotic assembly factors for the attachment of flavin to complex II. Biochimica et Biophysica Acta: Bioenergetics, 1827, 637-647. doi: 10.1016/j.bbabio.2012.09.003

Short, F. L., Pei, X. Y., Blower, T. R., Ong, S.-L., Fineran, P. C., Luisi, B. F., & Salmond, G. P. C. (2013). Selectivity and self-assembly in the control of a bacterial toxin by an antitoxic noncoding RNA pseudoknot. PNAS, 110(3), 820-821. doi: 10.1073/pnas.1216039110

Cook, G. M., Robson, J. R., Frampton, R. A., McKenzie, J., Przybilski, R., Fineran, P. C., & Arcus, V. L. (2013). Ribonucleases in bacterial toxin–antitoxin systems. Biochimica et Biophysica Acta: Gene Regulatory Mechanisms, 1829, 523-531. doi: 10.1016/j.bbagrm.2013.02.007

Sangal, V., Fineran, P. C., & Hoskisson, P. A. (2013). Novel configurations of type I and II CRISPR-Cas systems in Corynebacterium diphtheriae. Microbiology, 159(Pt 10), 2118-2126. doi: 10.1099/mic.0.070235-0

Fineran, P. C., Iglesias Cans, M. C., Ramsay, J. P., Wilf, N. M., Cossyleon, D., McNeil, M. B., … Stanton, J.-A. L., … Salmond, G. P. C. (2013). Draft genome sequence of Serratia sp. strain ATCC 39006, a model bacterium for analysis of the biosynthesis and regulation of prodigiosin, a carbapenem, and gas vesicles. Genome Announcements, 1(6), e01039-13. doi: 10.1128/genomeA.01039-13

McNeil, M. B., & Fineran, P. C. (2013). The conserved RGxxE motif of the bacterial FAD assembly factor SdhE is required for succinate dehydrogenase flavinylation and activity. Biochemistry, 52, 7628-7640. doi: 10.1021/bi401006a

Westra, E. R., Staals, R. H. J., Gort, G., Høgh, S., Neumann, S., de la Cruz, F., Fineran, P. C., & Brouns, S. J. J. (2013). CRISPR-Cas systems preferentially target the leading regions of MOBF conjugative plasmids. RNA Biology, 10(5), 749-761. doi: 10.4161/rna.24202

Biswas, A., Gagnon, J. N., Brouns, S. J. J., Fineran, P. C., & Brown, C. M. (2013). CRISPRTarget: Bioinformatic prediction and analysis of crRNA targets. RNA Biology, 10(5), 817-827. doi: 10.4161/rna.24046

Dy, R. L., Pitman, A. R., & Fineran, P. C. (2013). Chromosomal targeting by CRISPR-Cas systems can contribute to genome plasticity in bacteria. Mobile Genetic Elements, 3(5), e26831. doi: 10.4161/mge.26831

Blower, T. R., Evans, T. J., Przybilski, R., Fineran, P. C., & Salmond, G. P. C. (2012). Viral evasion of a bacterial suicide system by RNA–based molecular mimicry enables infectious altruism. PLoS Genetics, 8(10), e1003023. doi: 10.1371/journal.pgen.1003023

Richter, C., Gristwood, T., Clulow, J. S., & Fineran, P. C. (2012). In vivo protein interactions and complex formation in the Pectobacterium atrosepticum subtype I-F CRISPR/Cas system. PLoS ONE, 7(12), e49549. doi: 10.1371/journal.pone.0049549

Fineran, P. C., & Charpentier, E. (2012). Memory of viral infections by CRISPR-Cas adaptive immune systems: Acquisition of new information. Virology, 434, 202-209. doi: 10.1016/j.virol.2012.10.003

Richter, C., Chang, J. T., & Fineran, P. C. (2012). Function and regulation of clustered regularly interspaced short palindromic repeats (CRISPR) / CRISPR associated (Cas) systems. Viruses, 4(10), 2291-2311. doi: 10.3390/v4102291

Blower, T. R., Short, F. L., Fineran, P. C., & Salmond, G. P. C. (2012). Viral molecular mimicry circumvents abortive infection and suppresses bacterial suicide to make hosts permissive for replication. Bacteriophage, 2(4), 234-238. doi: 10.4161/bact.23830

Frampton, R. A., Pitman, A. R., & Fineran, P. C. (2012). Advances in bacteriophage-mediated control of plant pathogens. International Journal of Microbiology, 2012, 326452. doi: 10.1155/2012/326452

McNeil, M. B., Clulow, J. S., Wilf, N. M., Salmond, G. P. C., & Fineran, P. C. (2012). SdhE is a conserved protein required for the flavinylation of succinate dehydrogenase in bacteria. Journal of Biological Chemistry, 287(22), 18418-18428. doi: 10.1074/jbc.M111.293803

Blower, T. R., Short, F. L., Rao, F., Mizuguchi, K., Pei, X. Y., Fineran, P. C., … Salmond, G. P. C. (2012). Identification and classification of bacterial Type III toxin-antitoxin systems encoded in chromosomal and plasmid genomes. Nucleic Acids Research, 40(13), 6158-6173. doi: 10.1093/nar/gks231

Gristwood, T., McNeil, M. B., Clulow, J. S., Salmond, G. P. C., & Fineran, P. C. (2011). PigS and PigP regulate prodigiosin biosynthesis in Serratia via differential control of divergent operons, which include predicted transporters of sulfur-containing molecules. Journal of Bacteriology, 193(5), 1076-1085. doi: 10.1128/JB.00352-10

Blower, T. R., Pei, X. Y., Short, F. L., Fineran, P. C., Humphreys, D. P., Luisi, B. F., & Salmond, G. P. C. (2011). A processed noncoding RNA regulates an altruistic bacterial antiviral system. Nature Structural & Molecular Biology, 18(2), 185-191. doi: 10.1038/nsmb.1981

Przybilski, R., Richter, C., Gristwood, T., Clulow, J. S., Vercoe, R. B., & Fineran, P. C. (2011). Csy4 is responsible for CRISPR RNA processing in Pectobacterium atrosepticum. RNA Biology, 8(3), 517-528. doi: 10.4161/rna.8.3.15190

Blower, T. R., Fineran, P. C., Johnson, M. J., Toth, I. K., Humphreys, D. P., & Salmond, G. P. C. (2009). Mutagenesis and functional characterization of the RNA and protein components of the toxIN abortive infection and toxin-antitoxin locus of Erwinia. Journal of Bacteriology, 191(19), 6029-6039. doi: 10.1128/JB.00720-09

Fineran, P. C., Blower, T. R., Foulds, I. J., Humphreys, D. P., Lilley, K. S., & Salmond, G. P. C. (2009). The phage abortive infection system, toxIN, functions as a protein-RNA toxin-antitoxin pair. PNAS, 106(3), 894-899. doi: 10.1073/pnas.0808832106

Gristwood, T., Fineran, P. C., Everson, L., Williamson, N. R., & Salmond, G. P. (2009). The PhoBR two-component system regulates antibiotic biosynthesis in Serratia in response to phosphate. BMC Microbiology, 9, 112. doi: 10.1186/1471-2180-9-112

Williamson, N. R., Fineran, P. C., Ogawa, W., Woodley, L. R., & Salmond, G. P. C. (2008). Integrated regulation involving quorum sensing, a two-component system, a GGDEF/EAL domain protein and a post-transcriptional regulator controls swarming and RhIA-dependent surfactant biosynthesis in Serratia. Environmental Microbiology, 10(5), 1202-1217. doi: 10.1111/j.1462-2920.2007.01536.x

Gristwood, T., Fineran, P. C., Everson, L., & Salmond, G. P. C. (2008). PigZ, a TetR/AcrR family repressor, modulates secondary metabolism via the expression of a putative four-component resistance-nodulation-cell-division efflux pump, ZrpADBC, in Serratia sp. ATCC 39006. Molecular Microbiology, 69(2), 418-435. doi: 10.1111/j.1365-2958.2008.06291.x

Fineran, P. C., Williamson, N. R., Lilley, K. S., & Salmond, G. P. C. (2007). Virulence and prodigiosin antibiotic biosynthesis in Serratia are regulated pleiotropically by the GGDEF/EAL domain protein, PigX. Journal of Bacteriology, 189(21), 7653-7662.

Petty, N. K., Evans, T. J., Fineran, P. C., & Salmond, G. P. C. (2007). Biotechnological exploitation of bacteriophage research. Trends in Biotechnology, 25(1), 7-15.

Williamson, N. R., Fineran, P. C., Gristwood, T., Chawrai, S. R., Leeper, F. J., & Salmond, G. P. C. (2007). Anticancer and immunosuppressive properties of bacterial prodiginines. Future Microbiology, 2(6), 605-618.

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Journal - Research Other

Jackson, S. A., & Fineran, P. C. (2019). Bacterial dormancy curbs phage epidemics. Nature, 570, 173-174. doi: 10.1038/d41586-019-01595-8

Patterson, A. G., Yevstigneyeva, M. S., & Fineran, P. C. (2017). Regulation of CRISPR-Cas adaptive immune systems. Current Opinion in Microbiology, 37(1), 1-7. doi: 10.1016/j.mib.2017.02.004

Westra, E. R., Buckling, A., & Fineran, P. C. (2014). CRISPR-Cas systems: Beyond adaptive immunity. Nature Reviews Microbiology, 12, 317-326. doi: 10.1038/nrmicro3241

Williamson, N. R., Fineran, P. C., Leeper, F. J., & Salmond, G. P. C. (2006). The biosynthesis and regulation of bacterial prodiginines. Nature Reviews Microbiology, 4, 887-899. doi: 10.1038/nrmicro1531

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