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Health Sciences profile

Dr Aamir Raja

PositionSenior Research Fellow
DepartmentDepartment of Radiology (Christchurch)
QualificationsPhD
Research summaryImaging; radiology

Research

Aamir holds positions as a Research Fellow/Lecturer in the Centre for Bioengineering, Department of Radiology, and is a visiting research fellow at the University of Canterbury. His research interests are in the areas of radiation physics, medical imaging physics particularly radiation detection by small pixel detectors, and include biomedical imaging and spectral or multi-energy CT. He has always enjoyed interdisciplinary research.

His main research interest is in Spectral CT imaging and single photon counting detectors and to develop applications associated with this new technology. His vision is to translate his findings from the small animal spectral CT system to human spectral imaging. The interdisciplinary nature of this research encompasses physics, mathematics, engineering, biological sciences, computer science, and imaging sciences. He gets great pleasure from such a diversity of academic interactions both local and international. Previously, he was involved in Radiation oncology as a Medical Physicist at Shifa International Hospital, Pakistan”.

Publications

Bernabei, I., Sayous, Y., Raja, A. Y., Amma, M. R., Viry, A., Steinmetz, S., … Stamp, L. K., … Becce, F. (2021). Multi-energy photon-counting computed tomography versus other clinical imaging techniques for the identification of articular calcium crystal deposition. Rheumatology. Advance online publication. doi: 10.1093/rheumatology/keab125

Lowe, C., Ortega-Gil, A., Moghiseh, M., Anderson, N. G., Muñoz-Barrutia, A., Vaquero, J. J., Raja, A. Y., Matanaghi, A., … Dapamede, T., Adebileje, S. A., … Amma, M. R., … Asghariomabad, F., … Baer, K., … Butler, P. H., Carbonez, P., … Chapagain, K., … Crighton, J. S., Dahal, S., Damet, J., de Ruiter, N. J. A., … Gieseg, S. P., … Gurney, S., … Marfo, E., … Panta, R. K., … Schleich, N., … Butler, A. P. H. (2021). Molecular imaging of pulmonary tuberculosis in an ex-vivo mouse model using spectral photon-counting computed tomography and micro-CT. IEEE Access, 9, 67201-67208. doi: 10.1109/ACCESS.2021.3076432

Baer, K., Kieser, S., Schon, B., Rajendran, K., ten Harkel, T., Ramyar, M., … Bateman, C., Butler, A., Raja, A. Y., Hooper, G., Anderson, N., & Woodfield, T. (2021). Spectral CT imaging of human osteoarthritic cartilage via quantitative assessment of glycosaminoglycan content using multiple contrast agents. APL Bioengineering, 5(2), 026101. doi: 10.1063/5.0035312

Raja, A., Gieseg, S. P., Adebileje, S. A., Alexander, S. D., Amma, M. R., Asghariomabad, F., … Bamford, B., … Butler, A. P. H., Butler, P. H., Carbonez, P., … Dahal, S., Damet, J., de Ruiter, N. J. A., … Lowe, C., … Marfo, E., Matanaghi, A., Moghiseh, M., Panta, R. K., … Schleich, N., … Sheeja, J. S., … Wijesooriya, M. (2020). Spectral CT imaging using MARS scanners. In K. Taguchi, I. Blevis & K. Iniewski (Eds.), Spectral, photon counting computed tomography: Technology and applications. (pp. 117-138). Boca Raton, FL: CRC Press.

Ostadhossein, F., Tripathi, I., Benig, L., LoBato, D., Moghiseh, M., Lowe, C., Aamir, R., Butler, A., Panta, R., Anjomrouz, M., … Pan, D. (2020). Multi-"color" delineation of bone microdamages using ligand-directed sub-5 nm hafnia nanodots and photon counting CT imaging. Advanced Functional Materials, 30, 1904936. doi: 10.1002/adfm.201904936

Chapter in Book - Research

Raja, A., Gieseg, S. P., Adebileje, S. A., Alexander, S. D., Amma, M. R., Asghariomabad, F., … Bamford, B., … Butler, A. P. H., Butler, P. H., Carbonez, P., … Dahal, S., Damet, J., de Ruiter, N. J. A., … Lowe, C., … Marfo, E., Matanaghi, A., Moghiseh, M., Panta, R. K., … Schleich, N., … Sheeja, J. S., … Wijesooriya, M. (2020). Spectral CT imaging using MARS scanners. In K. Taguchi, I. Blevis & K. Iniewski (Eds.), Spectral, photon counting computed tomography: Technology and applications. (pp. 117-138). Boca Raton, FL: CRC Press.

Walsh, M. F., Aamir, R., Panta, R. K., Rajendran, K., Anderson, N. G., Butler, A. P. H., & Butler, P. H. (2015). Spectral molecular CT with photon-counting detectors. In S. Awadalla (Ed.), Solid-state radiation detectors: Technology and applications. (pp. 195-219). Boca Raton, FL: CRC Press.

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Journal - Research Article

Bernabei, I., Sayous, Y., Raja, A. Y., Amma, M. R., Viry, A., Steinmetz, S., … Stamp, L. K., … Becce, F. (2021). Multi-energy photon-counting computed tomography versus other clinical imaging techniques for the identification of articular calcium crystal deposition. Rheumatology. Advance online publication. doi: 10.1093/rheumatology/keab125

Baer, K., Kieser, S., Schon, B., Rajendran, K., ten Harkel, T., Ramyar, M., … Bateman, C., Butler, A., Raja, A. Y., Hooper, G., Anderson, N., & Woodfield, T. (2021). Spectral CT imaging of human osteoarthritic cartilage via quantitative assessment of glycosaminoglycan content using multiple contrast agents. APL Bioengineering, 5(2), 026101. doi: 10.1063/5.0035312

Lowe, C., Ortega-Gil, A., Moghiseh, M., Anderson, N. G., Muñoz-Barrutia, A., Vaquero, J. J., Raja, A. Y., Matanaghi, A., … Dapamede, T., Adebileje, S. A., … Amma, M. R., … Asghariomabad, F., … Baer, K., … Butler, P. H., Carbonez, P., … Chapagain, K., … Crighton, J. S., Dahal, S., Damet, J., de Ruiter, N. J. A., … Gieseg, S. P., … Gurney, S., … Marfo, E., … Panta, R. K., … Schleich, N., … Butler, A. P. H. (2021). Molecular imaging of pulmonary tuberculosis in an ex-vivo mouse model using spectral photon-counting computed tomography and micro-CT. IEEE Access, 9, 67201-67208. doi: 10.1109/ACCESS.2021.3076432

Ostadhossein, F., Tripathi, I., Benig, L., LoBato, D., Moghiseh, M., Lowe, C., Aamir, R., Butler, A., Panta, R., Anjomrouz, M., … Pan, D. (2020). Multi-"color" delineation of bone microdamages using ligand-directed sub-5 nm hafnia nanodots and photon counting CT imaging. Advanced Functional Materials, 30, 1904936. doi: 10.1002/adfm.201904936

Kanithi, P., de Ruiter, N. J. A., Amma, M. R., Lindeman, R. W., Butler, A. P. H., Butler, P. H., … Adebileje, S. A., … Asghariomabad, F., … Bamford, B., … Carbonez, P., … Clark, J. A., … Crighton, J. S., Dahal, S., Damet, J., … Gieseg, S. P., … Gurney, S. J., Healy, J. L., … Lowe, C., Marfo, E., Matanaghi, A., Moghiseh, M., … Panta, R. K., … Raja, A. Y., Renaud, P. F., … Schleich, N., … Sheeja, J. S., … Walker, E. P., … Younger, W. R. (2020). Interactive image segmentation of MARS datasets using bag of features. IEEE Transactions on Radiation & Plasma Medical Sciences. Advance online publication. doi: 10.1109/TRPMS.2020.3030045

Marfo, E., Anderson, N. G., Butler, A. P. H., Schleich, N., Carbonez, P., Damet, J., Lowe, C., Healy, J., … Moghiseh, M., MARS Collaboration, & Raja, A. Y. (2020). Assessment of material identification errors, image quality and radiation doses using small animal spectral photon-counting CT. IEEE Transactions on Radiation & Plasma Medical Sciences. Advance online publication. doi: 10.1109/TRPMS.2020.3003260

Bateman, C. J., Knight, D., Brandwacht, B., McMahon, J., Healy, J., Panta, R., Aamir, R., Rajendran, K., Moghiseh, M., Ramyar, M., … de Ruiter, N., … Shamshad, M., Anjomrouz, M., Atharifard, A., … Bheesette, S., … Anderson, N. G., Gieseg, S. P., Woodfield, T., Renaud, P. F., Butler, A. P. H., & Butler, P. H. (2018). MARS-MD: Rejection based image domain material decomposition. Journal of Instrumentation, 13, P05020. doi: 10.1088/1748-0221/13/05/p05020

Anjomrouz, M., Shamshad, M., Panta, R. K., Vanden Broeke, L., Schleich, N., Atharifard, A., Raja, A., Bheesette, S., Walsh, M. F., Goulter, B. P., … Bateman, C. J., Butler, A. P. H., & Butler, P. H. (2018). Beam profile assessment in spectral CT scanners. Journal of Applied Clinical Medical Physics, 19(2), 287-297. doi: 10.1002/acm2.12260

Panta, R. K., Bell, S. T., Healy, J. L., Aamir, R., Bateman, C. J., Moghiseh, M., Butler, A. P. H., & Anderson, N. G. (2018). Element-specific spectral imaging of multiple contrast agents: A phantom study. Journal of Instrumentation, 13, T02001. doi: 10.1088/1748-0221/13/02/T02001

Prebble, H., Cross, S., Marks, E., Healy, J. L., Searle, E., Aamir, R., Butler, A., Roake, J., Hock, B., Anderson, N., & Gieseg, S. P. (2018). Induced macrophage activation in live excised atherosclerotic plaque. Immunobiology, 223(8-9), 526-535. doi: 10.1016/j.imbio.2018.03.002

Moghiseh, M., Lowe, C., Lewis, J., Kumar, D., Butler, A., Anderson, N., & Raja, A. (2018). Spectral photon-counting molecular imaging for quantification of monoclonal antibody-conjugated gold nanoparticles targeted to lymphoma and breast cancer: An in vitro study. Contrast Media & Molecular Imaging, 2018, 2136840. doi: 10.1155/2018/2136840

Raja, A. Y., Moghiseh, M., Bateman, C. J., de Ruiter, N., Schon, B., Schleich, N., Woodfield, T. B. F., Butler, A. P. H., & Anderson, N. G. (2018). Measuring identification and quantification errors in spectral CT material decomposition. Applied Sciences, 8(3), 467. doi: 10.3390/app8030467

Kirkbride, T. E., Raja, A. Y., Müller, K., Bateman, C. J., Becce, F., & Anderson, N. G. (2017). Discrimination between calcium hydroxyapatite and calcium oxalate using multienergy spectral photon-counting CT. American Journal of Roentgenology, 209(5), 1088-1092. doi: 10.2214/ajr.17.18394

Shamshad, M., Anjomrouz, M., Smithies, D. J., Largeau, A., Lu, G., Atharifard, A., … Aamir, R., Panta, R. K., Walsh, M. F., Goulter, B. P., Healy, J. L., Bheesette, S., … Bateman, C. J., Butler, A. P. H., & Butler, P. H. (2017). Semi-analytic off-axis X-ray source model. Journal of Instrumentation, 12, P10013. doi: 10.1088/1748-0221/12/10/p10013

Rajendran, K., Löbker, C., Schon, B. S., Bateman, C. J., Younis, R. A., de Ruiter, N. J. A., … Ramyar, M., Hooper, G. J., Butler, A. P. H., Woodfield, T. B. F., & Anderson, N. G. (2017). Quantitative imaging of excised osteoarthritic cartilage using spectral CT. European Radiology, 27(1), 384-392. doi: 10.1007/s00330-016-4374-7

Moghiseh, M., Aamir, R., Panta, R. K., de Ruiter, N., Chernoglazov, A., Healy, J. L., Butler, A. P. H., & Anderson, N. G. (2016). Discrimination of multiple high-Z materials by multi-energy spectral CT: A phantom study. JSM Biomedical Imaging Data Papers, 3(1), 1007.

Rajendran, K., Walsh, M. F., de Ruiter, N. J. A., Chernoglazov, A. I., Panta, R. K., Butler, A. P. H., … Anderson, N. G., Woodfield, T. B. F., Tredinnick, S. J., … Bateman, C. J., Aamir, R., … Smithies, D. J., Mohr, J. L., … Ronaldson, J. P., … Atharifard, A., … Schleich, N., & Billinghurst, M. (2014). Reducing beam hardening effects and metal artefacts in spectral CT using Medipix3RX. Journal of Instrumentation, 9, P03015. doi: 10.1088/1748-0221/9/03/P03015

Aamir, R., Chernoglazov, A., Bateman, C. J., Butler, A. P. H., Butler, P. H., Anderson, N. G., … Panta, R. K., … Mohr, J. L., Rajendran, K., Walsh, M. F., de Ruiter, N., Gieseg, S. P., Woodfield, T., … Schleich, N., Scott, N., … Ronaldson, J. P., Cook, N. J., … Hodge, K. (2014). MARS spectral molecular imaging of lamb tissue: Data collection and image analysis. Journal of Instrumentation, 9, P02005. doi: 10.1088/1748-0221/9/02/P02005

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Journal - Research Other

Becce, F., Viry, A., Stamp, L. K., Pascart, T., Budzik, J.-F., MARS Collaboration, & Raja, A. (2020). Du nouveau dans l’imagerie des maladies à dépôts de cristaux de calcium. Revue du Rhumatisme, 87, 235-238. doi: 10.1016/j.rhum.2020.01.029

Stamp, L. K., Anderson, N. G., Becce, F., Rajeswari, M., Polson, M., Guyen, O., … Choi, C., … Raja, A. Y. (2019). Clinical utility of multi-energy spectral photon-counting computed tomography in crystal arthritis [Brief report]. Arthritis & Rheumatology, 71(7), 1158-1162. doi: 10.1002/art.40848

Becce, F., Viry, A., Stamp, L. K., Pascart, T., Budzik, J.-F., MARS Collaboration, & Raja, A. (2019). Winds of change in imaging of calcium crystal deposition diseases. Joint Bone Spine, 86(6), 665-668. doi: 10.1016/j.jbspin.2019.04.005

Yu, H., Xu, Q., He, P., Bennett, J., Aamir, R., Dobbs, B., … Butler, A., … Wang, G. (2012). Medipix-based spectral micro-CT. Computerized Tomography Theory & Applications, 21(4), 583-596.

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