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Health Sciences profile

Isabelle Kuan

PositionPhD Student
Research summaryModel-based estimation of glomerular filtration rate

Additional details

Supervised by Dr Dan Wright and Professor Steve Duffull, and sponsored by NZPERF.

Publications

Kuan, I. H. S., Wilson, L. C., Leishman, J. C., Cosgrove, S., Walker, R. J., Putt, T. L., Schollum, J. B. W., & Wright, D. F. B. (2021). Metformin doses to ensure efficacy and safety in patients with reduced kidney function. PLoS ONE, 16(2), e0246247. doi: 10.1371/journal.pone.0246247

Ji, X.-W., Xue, F., Kang, Z.-S., Zhong, W., Kuan, I. H.-s., Yang, X.-P., Zhu, X., … Lv, Y. (2020). Model-informed drug development, pharmacokinetic/pharmacodynamic cutoff value determination, and antibacterial efficacy of benapenem against Enterobacteriaceae. Antimicrobial Agents & Chemotherapy, 64(3), e01751-19. doi: 10.1128/aac.01751-19

Kuan, I. H. S., Wright, D. F. B., Duffull, S. B., & Zhu, X. (2020). Understanding the association between metformin plasma concentrations and lactate. British Journal of Clinical Pharmacology. Advance online publication. doi: 10.1111/bcp.14394

Sinnappah, K. A., Kuan, I. H. S., Thynne, T. R. J., Doogue, M. P., & Wright, D. F. B. (2020). The pharmacokinetics of metformin in patients receiving intermittent haemodialysis [Short report]. British Journal of Clinical Pharmacology, 86, 1430-1443. doi: 10.1111/bcp.14244

Kuan, I. H. S., Savage, R. L., Duffull, S. B., Walker, R. J., & Wright, D. F. B. (2019). The association between metformin therapy and lactic acidosis. Drug Safety, 42, 1449-1469. doi: 10.1007/s40264-019-00854-x

Journal - Research Article

Kuan, I. H. S., Wilson, L. C., Leishman, J. C., Cosgrove, S., Walker, R. J., Putt, T. L., Schollum, J. B. W., & Wright, D. F. B. (2021). Metformin doses to ensure efficacy and safety in patients with reduced kidney function. PLoS ONE, 16(2), e0246247. doi: 10.1371/journal.pone.0246247

Ji, X.-W., Xue, F., Kang, Z.-S., Zhong, W., Kuan, I. H.-s., Yang, X.-P., Zhu, X., … Lv, Y. (2020). Model-informed drug development, pharmacokinetic/pharmacodynamic cutoff value determination, and antibacterial efficacy of benapenem against Enterobacteriaceae. Antimicrobial Agents & Chemotherapy, 64(3), e01751-19. doi: 10.1128/aac.01751-19

Kuan, I. H. S., Savage, R. L., Duffull, S. B., Walker, R. J., & Wright, D. F. B. (2019). The association between metformin therapy and lactic acidosis. Drug Safety, 42, 1449-1469. doi: 10.1007/s40264-019-00854-x

Kuan, I. H. S., Duffull, S. B., Putt, T. L., Schollum, J. B. W., Walker, R. J., & Wright, D. F. B. (2017). A population pharmacokinetic model for 51Cr EDTA to estimate renal function. Clinical Pharmacokinetics, 56(6), 671-678. doi: 10.1007/s40262-016-0489-x

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Journal - Research Other

Kuan, I. H. S., Wright, D. F. B., Duffull, S. B., & Zhu, X. (2020). Understanding the association between metformin plasma concentrations and lactate. British Journal of Clinical Pharmacology. Advance online publication. doi: 10.1111/bcp.14394

Sinnappah, K. A., Kuan, I. H. S., Thynne, T. R. J., Doogue, M. P., & Wright, D. F. B. (2020). The pharmacokinetics of metformin in patients receiving intermittent haemodialysis [Short report]. British Journal of Clinical Pharmacology, 86, 1430-1443. doi: 10.1111/bcp.14244

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