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Health Sciences profile

Associate Professor Peter Larsen

PositionAssociate Professor and Head of Department
DepartmentsDepartment of Radiation Therapy (Wellington), Department of Surgery and Anaesthesia (Wellington)
QualificationsBSc(Hons), PhD (Otago)
Research summaryClinical cardiovascular medicine

Research

After completing a BSc with Honours at Victoria University of Wellington, I undertook a PhD at the University of Otago. This focused on understanding the interactions between cardiovascular and respiratory control. I then did a postdoctoral fellowship at Michigan State University examined neural control of the cardiovascular system, before returning to the University of Otago, Wellington.

My research interests are now in clinical cardiovascular medicine, including the use of biomarkers in risk stratification, acute myocardial infarction, use of implanted cardiac devices and personalised approaches to clinical care.

Application of cardiovascular physiology to clinical questions remains an area of interest for me. In addition, I am involved in supporting registrar research activities in a range of clinical settings.

Publications

Brunton-O'Sullivan, M. M., Holley, A. S., Shi, B., Harding, S. A., & Larsen, P. D. (2022). Cluster analysis of extracellular matrix biomarkers predicts the development of impaired systolic function within 1 year of acute myocardial infarction. Heart & Vessels. Advance online publication. doi: 10.1007/s00380-022-02118-8

Hally, K. E., Ferrer-Font, L., Pilkington, K. R., & Larsen, P. D. (2022). OMIP 083: A 21-marker 18-color flow cytometry panel for in-depth phenotyping of human peripheral monocytes. Cytometry Part A. Advance online publication. doi: 10.1002/cyto.a.24545

Brunton-O'Sullivan, M. M., Holley, A. S., Bird, G. K., Kristono, G. A., Harding, S. A., & Larsen, P. D. (2022). Examining variation and temporal dynamics of extracellular matrix biomarkers following acute myocardial infarction. Biomarkers in Medicine, 16(3), 147-161. doi: 10.2217/bmm-2021-0531

Yiu, J. Y. T., Hally, K. E., Larsen, P. D., & Holley, A. S. (2022). Increased levels of low density neutrophils (LDNs) in myocardial infarction. Acta Cardiologica. Advance online publication. doi: 10.1080/00015385.2021.2015145

Rogan, A., Brunton-O'Sullivan, M., Holley, A., McQuade, D. d., & Larsen, P. (2022). Can serum biomarkers be used to rule out significant intracranial pathology in emergency department patients with mild traumatic brain injury? A systemic review & meta-analysis. Injury, 53, 259-271. doi: 10.1016/j.injury.2021.10.015

Brunton-O'Sullivan, M. M., Holley, A. S., Bird, G. K., Kristono, G. A., Harding, S. A., & Larsen, P. D. (2022). Examining variation and temporal dynamics of extracellular matrix biomarkers following acute myocardial infarction. Biomarkers in Medicine, 16(3), 147-161. doi: 10.2217/bmm-2021-0531

Journal - Research Article

Brunton-O'Sullivan, M. M., Holley, A. S., Shi, B., Harding, S. A., & Larsen, P. D. (2022). Cluster analysis of extracellular matrix biomarkers predicts the development of impaired systolic function within 1 year of acute myocardial infarction. Heart & Vessels. Advance online publication. doi: 10.1007/s00380-022-02118-8

Journal - Research Article

Rogan, A., Brunton-O'Sullivan, M., Holley, A., McQuade, D. d., & Larsen, P. (2022). Can serum biomarkers be used to rule out significant intracranial pathology in emergency department patients with mild traumatic brain injury? A systemic review & meta-analysis. Injury, 53, 259-271. doi: 10.1016/j.injury.2021.10.015

Journal - Research Article

Yiu, J. Y. T., Hally, K. E., Larsen, P. D., & Holley, A. S. (2022). Increased levels of low density neutrophils (LDNs) in myocardial infarction. Acta Cardiologica. Advance online publication. doi: 10.1080/00015385.2021.2015145

Journal - Research Article

Brunton-O'Sullivan, M. M., Holley, A. S., Hally, K. E., Kristono, G. A., Harding, S. A., & Larsen, P. D. (2021). A combined biomarker approach for characterising extracellular matrix profiles in acute myocardial infarction. Scientific Reports, 11, 12705. doi: 10.1038/s41598-021-92108-z

Journal - Research Article

Gunawardene, A., Manning, S., Holley, A., Kristono, G., Danielson, K., Shekouh, A., Larsen, P., & Dennett, E. (2021). An IL8-CEA combined score is stage-specific in colorectal cancer. Surgery, Gastroenterology & Oncology, 26(4), 284-290. doi: 10.21614/sgo-26-4-401

Journal - Research Article

Hally, K. E., Parker, O. M., Brunton-O'Sullivan, M. M., Harding, S. A., & Larsen, P. D. (2021). Linking neutrophil extracellular traps and platelet activation: A composite biomarker for predicting outcomes after acute myocardial infarction. Thrombosis & Haemostasis, 121, 1637-1649. doi: 10.1055/s-0041-1728763

Journal - Research Article

Marsters, B., Shi, B., Wheeler, B. J., Boucher, S., Macaulay, G., Galland, B., Elder, D., Larsen, P., & Wiltshire, E. (2021). Advanced ECG analysis of cardiac function in children and adolescents with type 1 diabetes: A pilot study. Acta Diabetologica, 58, 1119-1122. doi: 10.1007/s00592-021-01704-y

Journal - Research Article

Mouat, M., Gunawardene, A., Sweetman, L., Dennett, E., & Larsen, P. (2021). Psoas muscle cross-sectional area and outcomes following colorectal cancer surgery. British Journal of Surgical Science, 1(2), 39-45.

Journal - Research Article

Rogan, A., Patel, V., Birdling, J., Lockett, J., Simmonds, H., McQuade, D., & Larsen, P. (2021). Acute traumatic brain injury and the use of head computed tomography scans in the emergency department. Trauma. Advance online publication. doi: 10.1177/14604086211023646

Journal - Research Article

Rogan, A., Patel, V., Birdling, J., Lockett, J., Simmonds, H., McQuade, D., Quigley, P., & Larsen, P. (2021). Alcohol and acute traumatic brain injury in the emergency department. Emergency Medicine Australasia, 33, 718-727. doi: 10.1111/1742-6723.13726

Journal - Research Article

Ady Wirawan, I. M., Griffiths, R. F., & Larsen, P. D. (2020). Cardiovascular risk factor modification in asymptomatic adults and implications for pilots. Journal of UOEH, 42(2), 187-201. doi: 10.7888/juoeh.42.187

Journal - Research Article

de Burlet, K. J., Desmond, B., Matsis, R., Harper, S. J., Larsen, P. D., & Dennett, E. R. (2020). Reducing length of stay for patients presenting to general surgery with acute non-surgical abdominal pain. ANZ Journal of Surgery, 90, 2259-2263. doi: 10.1111/ans.16276

Journal - Research Article

Foo, F. S., Lee, M., Looi, K.-L., Larsen, P., Clare, G. C., Heaven, D., … on behalf of the ANZACS-QI investigators. (2020). Implantable cardioverter defibrillator and cardiac resynchronization therapy use in New Zealand (ANZACS-QI 33). Journal of Arrhythmia, 36, 153-163. doi: 10.1002/joa3.12244

Journal - Research Article

Hally, K. E., Holley, A. S., Kristono, G. A., Harding, S. A., & Larsen, P. D. (2020). Immunoglobulin G levels predicts risk of recurrent adverse cardiovascular events in myocardial infarction patients. Acta Cardiologica, 75(6), 497-502. doi: 10.1080/00015385.2019.1611189

Journal - Research Article

Kane, P., Larsen, P., & Wiltshire, E. (2020). Early identification of cardiac autonomic neuropathy using complexity analysis in children with type 1 diabetes. Journal of Paediatrics & Child Health, 56, 786-790. doi: 10.1111/jpc.14745

Journal - Research Article

Kristono, G. A., Holley, A. S., Hally, K. E., Brunton-O'Sullivan, M. M., Shi, B., Harding, S. A., & Larsen, P. D. (2020). An IL-6-IL-8 score derived from principal component analysis is predictive of adverse outcome in acute myocardial infarction. Cytokine: X, 2, 100037. doi: 10.1016/j.cytox.2020.100037

Journal - Research Article

Kristono, G. A., Holley, A. S., Harding, S. A., & Larsen, P. D. (2020). White blood cell subtypes as predictors of adverse cardiac events. Coronary Artery Disease, 31(5), 446-450. doi: 10.1097/mca.0000000000000860

Journal - Research Article

Kristono, G. A., Holley, A. S., Lakshman, P., Brunton-O'Sullivan, M. M., Harding, S. A., & Larsen, P. D. (2020). Association between inflammatory cytokines and long-term adverse outcomes in acute coronary syndromes: A systematic review. Heliyon, 6(4), e03704. doi: 10.1016/j.heliyon.2020.e03704

Journal - Research Article

Bond, E. C., Phillips, P., Larsen, P. D., Hunt, L., & Willoughby, R. (2019). Long-term hip function in slipped capital femoral epiphysis treated with in situ pinning. Journal of Orthopaedic Surgery, 27(1), 1-6. doi: 10.1177/2309499018822234

Journal - Research Article

de Burlet, K. J., Lam, A. B. M., Harper, S. J., Larsen, P. D., & Dennett, E. R. (2019). Can surgical registrars accurately identify the urgent from the non-urgent patient presenting with acute abdominal pain? European Surgical Research, 60(1-2), 24-30. doi: 10.1159/000496021

Journal - Research Article

Foo, F. S., Lee, M., Heaven, D., Lever, N., Sinclair, S., Stiles, M. K., Harding, S., … Larsen, P., … on behalf of the ANZACS-QI investigators. (2019). Completeness of ANZACS-QI Cardiac Implanted DEVICE Registry and agreement with national datasets: ANZACS-QI 30. New Zealand Medical Journal, 132(1500), 40-49. Retrieved from https://www.nzma.org.nz/journal

Journal - Research Article

Hally, K. E., Bird, G. K., La Flamme, A. C., Harding, S. A., & Larsen, P. D. (2019). Platelets modulate multiple markers of neutrophil function in response to in vitro Toll-like receptor stimulation. PLoS ONE, 14(10), e0223444. doi: 10.1371/journal.pone.0223444

Journal - Research Article

Hally, K. E., La Flamme, A. C., Harding, S. A., & Larsen, P. D. (2019). The effects of aspirin and ticagrelor on Toll-like receptor (TLR)-mediated platelet activation: Results of a randomized, cross-over trial. Platelets, 30(5), 599-607. doi: 10.1080/09537104.2018.1479520

Journal - Research Article

Hancock, D. S., Sharplin, P. K., Larsen, P. D., & Phillips, F. T. S. (2019). Early radiological and functional outcomes for a cementless press-fit design modular femoral stem revision system. HIP International, 29(1), 35-40. doi: 10.1177/1120700018760277

Journal - Research Article

Tinawi, G., Gunawardene, A., Shekouh, A., Larsen, P. D., & Dennett, E. R. (2019). Neoadjuvant therapy in rectal cancer: How are we choosing? ANZ Journal of Surgery, 89, 68-73. doi: 10.1111/ans.14935

Journal - Research Article

Wilkins, B., Hullikunte, S., Simmonds, M., Sasse, A., Larsen, P., & Harding, S. A. (2019). Improving the prescribing gap for guideline recommended medications post myocardial infarction. Heart, Lung & Circulation, 28(2), 257-262. doi: 10.1016/j.hlc.2017.10.025

Journal - Research Article

Ady Wirawan, I. M., Griffiths, R. F., & Larsen, P. D. (2018). Cardiovascular tests for risk assessment in asymptomatic adults and implications for pilots. Aerospace Medicine & Human Performance, 89(7), 648-656. doi: 10.3357/amhp.5065.2018

Journal - Research Article

de Burlet, K. J., Desmond, B., Harper, S. J., Larsen, P. D., & Dennett, E. R. (2018). Patients requiring an acute operation: Where are the delays in the process? ANZ Journal of Surgery, 88, 865-869. doi: 10.1111/ans.14718

Journal - Research Article

de Burlet, K. J., MacKay, M., Larsen, P., & Dennett, E. R. (2018). Appropriateness of CT scans for patients with non-traumatic acute abdominal pain. British Journal of Radiology, 91(1088), 20180158. doi: 10.1259/bjr.20180158

Journal - Research Article

Gunawardene, A., Desmond, B., Shekouh, A., Larsen, P., & Dennett, E. (2018). Disease recurrence following surgery for colorectal cancer: Five-year follow-up. New Zealand Medical Journal, 131(1469), 51-58. Retrieved from https://www.nzma.org.nz/journal

Journal - Research Article

Gunawardene, A., Larsen, P., Shekouh, A., & Dennett, E. (2018). Pre-operative carcinoembryonic antigen predicts survival following colorectal cancer surgery with curative intent. ANZ Journal of Surgery, 88, 1311-1315. doi: 10.1111/ans.14723

Journal - Research Article

Hally, K. E., La Flamme, A. C., Harding, S. A., & Larsen, P. D. (2018). Platelets regulate leucocyte responses to Toll-like receptor stimulation. Clinical & Translational Immunology, 7, e1036. doi: 10.1002/cti2.1036

Journal - Research Article

Hancock, D. S., Rupasinghe, S. L., Elkinson, I., Bloomfield, M. G., & Larsen, P. D. (2018). Benzoyl peroxide + chlorhexidine versus chlorhexidine alone skin preparation to reduce Propionibacterium acnes: A randomized controlled trial. ANZ Journal of Surgery, 88, 1182-1186. doi: 10.1111/ans.14848

Journal - Research Article

O'Connor, M., Hooks, D., Webber, M., Shi, B., Morrison, S., Harding, S., & Larsen, P. (2018). Long-term single-center comparison of ICD lead survival: Evidence for premature Linox lead failure. Journal of Cardiovascular Electrophysiology, 29(7), 1024-1031. doi: 10.1111/jce.13502

Journal - Research Article

de Burlet, K., Lam, A., Larsen, P., & Dennett, E. (2017). Acute abdominal pain: Changes in the way we assess it over a decade. New Zealand Medical Journal, 130(1463), 39-44. Retrieved from https://www.nzma.org.nz/journal

Journal - Research Article

Hally, K. E., La Flamme, A. C., Larsen, P. D., & Harding, S. A. (2017). Platelet Toll-like receptor (TLR) expression and TLR-mediated platelet activation in acute myocardial infarction. Thrombosis Research, 158, 8-15. doi: 10.1016/j.thromres.2017.07.031

Journal - Research Article

Harding, S. A., Holley, A., Wilkins, B., Fairley, S., Simmonds, M., & Larsen, P. D. (2017). Contemporary antiplatelet therapy in acute coronary syndromes: Are there differences in outcomes and discontinuation between clopidogrel and ticagrelor? Internal Medicine Journal, 47(11), 1298-1305. doi: 10.1111/imj.13595

Journal - Research Article

Holley, A., Pitman, J., Miller, J., Harding, S., & Larsen, P. (2017). Glutathione peroxidase activity and expression levels are significantly increased in acute coronary syndromes. Journal of Investigative Medicine, 65(5), 919-925. doi: 10.1136/jim-2016-000361

Journal - Research Article

Larsen, P. D., Holley, A. S., Sasse, A., Al-Sinan, A., Fairley, S., & Harding, S. A. (2017). Comparison of Multiplate and VerifyNow platelet function tests in predicting clinical outcome in patients with acute coronary syndromes. Thrombosis Research, 152, 14-19. doi: 10.1016/j.thromres.2017.02.006

Journal - Research Article

Larsen, P. D., Kerr, A. J., Hood, M., Harding, S. A., Hooks, D., Heaven, D., … on behalf of the ANZACS-QI Investigators. (2017). Pacemaker use in New Zealand: Data from the New Zealand Implanted Cardiac Device Registry (ANZACS-QI 15). Heart, Lung & Circulation, 26(3), 235-239. doi: 10.1016/j.hlc.2016.06.1206

Journal - Research Article

Matsis, K., Holley, A., Al-Sinan, A., Matsis, P., Larsen, P. D., & Harding, S. A. (2017). Differing clinical characteristics between young and older patients presenting with myocardial infarction. Heart, Lung & Circulation, 26(6), 566-571. doi: 10.1016/j.hlc.2016.09.007

Journal - Research Article

Roberts, T., Campbell, A., Larsen, P., & Elder, D. (2017). Preterm infants at discharge: Nap polysomnography versus 24-hour oximetry. Acta Paediatrica, 106(111), 1754-1759. doi: 10.1111/apa.13900

Journal - Research Article

Shi, B., Harding, S., & Larsen, P. (2017). Analysis of ECG measures of cardiac repolarization in relation to arrhythmic events in an implantable cardioverter defibrillator population. Annals of Noninvasive Electrocardiology, 22(2), e12390. doi: 10.1111/anec.12390

Journal - Research Article

Fake, A. L., Harding, S. A., Matsis, P. P., & Larsen, P. D. (2016). Pharmacological therapy following acute coronary syndromes in patients with atrial fibrillation: How do we balance ischaemic risk with bleeding risk? New Zealand Medical Journal, 129(1435), 39-49. Retrieved from https://www.nzma.org.nz/journal

Journal - Research Article

Hally, K. E., La Flamme, A. C., Larsen, P. D., & Harding, S. A. (2016). Toll-like receptor 9 expression and activation in acute coronary syndrome patients on dual anti-platelet therapy. Thrombosis Research, 148, 89-95. doi: 10.1016/j.thromres.2016.10.026

Journal - Research Article

Holley, A. S., Miller, J. H., Larsen, P. D., & Harding, S. A. (2016). Relationship between glutathione peroxidase, platelet reactivity, and reactive oxygen species in an acute coronary syndrome population. Annals of Clinical & Laboratory Science, 46(6), 639-644.

Journal - Research Article

Holley, A., Harding, S., Sasse, A., Miller, J., & Larsen, P. (2016). Reduced glutathione peroxidase activity predicts increased cardiovascular risk following an acute coronary syndrome. International Cardiovascular Forum Journal, 6, 61-65. doi: 10.17987/icfj.v6i0.241

Journal - Research Article

Nichol, G., Brown, S. P., Perkins, G. D., Kim, F., Sterz, F., Elrod, J. A. B., … Larsen, P., … Sayre, M. (2016). What change in outcomes after cardiac arrest is necessary to change practice? Results of an international survey. Resuscitation, 107, 115-120. doi: 10.1016/j.resuscitation.2016.08.004

Journal - Research Article

Wolbinski, M., Swain, A. H., Harding, S. A., & Larsen, P. D. (2016). Out-of-hospital cardiac arrest patient characteristics: Comparing ventricular arrthymia and pulseless electrical activity. Heart, Lung & Circulation, 25(7), 639-644. doi: 10.1016/j.hlc.2016.02.001

Journal - Research Article

Furniss, G., Shi, B., Jimenez, A., Harding, S. A., & Larsen, P. D. (2015). Cardiac troponin levels following implantable cardioverter defibrillation implantation and testing. Europace, 17(2), 262-266. doi: 10.1093/europace/euu306

Journal - Research Article

Johnston, J. W., Larsen, P., El-Haddawi, F. H., Fancourt, M. W., Farrant, G. J., Gilkison, W. T. C., … Mosquera, D. A. (2015). Time delays in presentation and treatment of acute scrotal pain in a provincial hospital. ANZ Journal of Surgery, 85(5), 330-333. doi: 10.1111/ans.12601

Journal - Research Article

Larsen, P. D., Johnston, L. R., Holley, A., La Flamme, A., Smyth, L., Chua, E. W., Kennedy, M. A., & Harding, S. A. (2015). Prevalence and significance of CYP2C19*2 and CYP2C19*17 alleles in a New Zealand acute coronary syndrome population. Internal Medicine Journal, 45(5), 537-545. doi: 10.1111/imj.12698

Journal - Research Article

Webb, I. G., Yam, S. T., Cooke, R., Aitken, A., Larsen, P. D., & Harding, S. A. (2015). Elevated baseline cardiac troponin levels in the elderly: Another variable to consider? Heart, Lung & Circulation, 24(2), 142-148. doi: 10.1016/j.hlc.2014.07.071

Journal - Research Article

Ady Wirawan, I. M., Wu, R., Abernethy, M., Aldington, S., & Larsen, P. D. (2014). Calcium scores in the risk assessment of an asymptomatic population: Implications for airline pilots. Aviation, Space, & Environmental Medicine, 85(8), 812-817. doi: 10.3357/ASEM.3904.2014

Journal - Research Article

Shi, B., Ferrier, K. A., Sasse, A., Harding, S. A., & Larsen, P. D. (2014). Correlation between vectorcardiographic measures and cardiac magnetic resonance imaging of the left ventricle in an implantable cardioverter defibrillator population. Journal of Electrocardiology, 47(1), 52-58. doi: 10.1016/j.jelectrocard.2013.06.018

Journal - Research Article

Ady Wirawan, I. M., Aldington, S., Griffiths, R. F., Ellis, C. J., & Larsen, P. D. (2013). Cardiovascular investigations of airline pilots with excessive cardiovascular risk. Aviation, Space, & Environmental Medicine, 84(6), 608-612. doi: 10.3357/ASEM.3465.2013

Journal - Research Article

Fake, A. L., Swain, A. H., & Larsen, P. D. (2013). Survival from out-of-hospital cardiac arrest in Wellington in relation to socioeconomic status and arrest location. New Zealand Medical Journal, 126(1376). Retrieved from http://www.nzma.org.nz/journal

Journal - Research Article

Harding, S. A., Shah, N., Briggs, N., Sasse, A., & Larsen, P. D. (2013). Complex transradial percutaneous coronary intervention using a sheathless guide catheter. Heart, Lung & Circulation, 22(3), 188-192. doi: 10.1016/j.hlc.2012.10.004

Journal - Research Article

Johnston, L. R., Larsen, P. D., La Flamme, A. C., & Harding, S. A. (2013). Methodological considerations for the assessment of ADP induced platelet aggregation using the Multiplate® analyser. Platelets, 24(4), 303-307. doi: 10.3109/09537104.2012.694086

Journal - Research Article

Johnston, L. R., Larsen, P. D., La Flamme, A. C., Michel, J. M., Simmonds, M. B., & Harding, S. A. (2013). Suboptimal response to clopidogrel and the effect of prasugrel in acute coronary syndromes. International Journal of Cardiology, 167(3), 995-999. doi: 10.1016/j.ijcard.2012.03.080

Journal - Research Article

Shi, B., Harding, S. A., Jimenez, A., & Larsen, P. D. (2013). Standard 12-lead electrocardiography measures predictive of increased appropriate therapy in implantable cardioverter defibrillator recipients. Europace, 15(6), 892-898. doi: 10.1093/europace/eus360

Journal - Research Article

Tomkins, W. G. O., Swain, A. H., Bailey, M., & Larsen, P. D. (2013). Beyond the pre-shock pause: The effect of prehospital defibrillation mode on CPR interruptions and return of spontaneous circulation. Resuscitation, 84, 575-579. doi: 10.1016/j.resuscitation.2012.12.018

Journal - Research Article

Elder, D. E., Larsen, P. D., Campbell, A. J., & Galletly, D. C. (2012). Cardioventilatory coupling and inter-breath variability in children referred for polysomnography. Respiratory Physiology & Neurobiology, 181(1), 1-7. doi: 10.1016/j.resp.2012.01.006

Journal - Research Article

Hoyle, S., Swain, A. H., Fake, P., & Larsen, P. D. (2012). Introduction of an extended care paramedic model in New Zealand. Emergency Medicine Australasia, 24(6), 652-656. doi: 10.1111/j.1742-6723.2012.01608.x

Journal - Research Article

Myers, J. A., Psirides, A., Hathaway, K., & Larsen, P. D. (2012). Air transport by the Wellington Flight Service: A descriptive analysis of interhospital transfers over a 5-year period in the Wellington region of New Zealand. New Zealand Medical Journal, 125(1351). Retrieved from http://www.nzma.org.nz/journal

Journal - Research Article

Swain, A. H., Al-Salami, M., Larsen, P. D., & Hoyle, S. R. (2012). Patient satisfaction and outcome using emergency care practitioners in New Zealand. Emergency Medicine Australasia, 24(2), 175-180. doi: 10.1111/j.1742-6723.2011.01525.x

Journal - Research Article

Sykes, A. J., Larsen, P. D., Griffiths, R. F., & Aldington, S. (2012). A study of airline pilot morbidity. Aviation, Space, & Environmental Medicine, 83(10), 1001-1005. doi: 10.3357/asem.3380.2012

Journal - Research Article

Wilson, D., Harding, S. A., Melton, I., Lever, N. A., Stiles, M. K., Boddington, D., Heald, S., & Larsen, P. D. (2012). Geographic, ethnic and socioeconomic factors influencing access to implantable cardioverter defibrillators (ICDs) in New Zealand. Heart, Lung & Circulation, 21(9), 576-581. doi: 10.1016/j.hlc.2012.04.012

Journal - Research Article

Wirawan, I. M. A., Larsen, P. D., Aldington, S., Griffiths, R. F., & Ellis, C. J. (2012). Cardiovascular risk score and cardiovascular events among airline pilots: A case-control study. Aviation, Space, & Environmental Medicine, 83(5), 465-471. doi: 10.3357/ASEM.3222.2012

Journal - Research Article

Zaidi, M. A., Griffiths, R. F., Larsen, P. D., Newson-Smith, M., & Zaidi, M. A. (2012). The reporting of blood and body fluid exposure and follow-up practices in a tertiary care hospital in the United Arab Emirates. Ibnosina Journal of Medicine & Biomedical Sciences, 4(3), 84-89.

Journal - Research Article

Burgess, S. N., Harding, S. A., Melton, I. C., Lever, N. A., Swain, A. H., Shi, B., & Larsen, P. D. (2011). An unmet need for implantable cardioverter-defibrillators in New Zealand. Europace, 13(9), 1299-1303. doi: 10.1093/europace/eur113

Journal - Research Article

Elder, D. E., Campbell, A. J., Larsen, P. D., & Galletly, D. (2011). Respiratory variability in preterm and term infants: Effect of sleep state, position and age. Respiratory Physiology & Neurobiology, 175(2), 234-238. doi: 10.1016/j.resp.2010.11.011

Journal - Research Article

Mahony, P. H., Myers, J. A., Larsen, P. D., Powell, D. M., & Griffiths, R. F. (2011). Symptom-based categorization of in-flight passenger medical incidents. Aviation, Space, & Environmental Medicine, 82(12), 1131-1137. doi: 10.3357/ASEM.3099.2011

Journal - Research Article

Swain, A. H., Barry, T., Hoyle, S. R., Haywood, G., Cameron, H., & Larsen, P. D. (2011). Outcomes from out-of-hospital cardiac arrest in the Wellington region of New Zealand: Does use of the Fire Service make a difference? New Zealand Medical Journal, 124(1344). Retrieved from http://journal.nzma.org.nz/journal/124-1344/4913/content.pdf

Journal - Research Article

Elder, D. E., Larsen, P. D., Galletly, D. C., & Campbell, A. J. (2010). Cardioventilatory coupling in preterm and term infants: Effect of position and sleep state. Respiratory Physiology & Neurobiology, 174(1-2), 128-134. doi: 10.1016/j.resp.2010.05.012

Journal - Research Article

Larsen, P. D., De Silva, P., Harding, S. A., Woodcock, E., & Lever, N. A. (2010). Use of implantable cardioverter defibrillators in the New Zealand context from 2000 to 2007. New Zealand Medical Journal, 123(1309). Retrieved from http://journal.nzma.org.nz/journal/123-1309/3977/content.pdf

Journal - Research Article

Larsen, P. D., Tzeng, Y. C., Sin, P. Y. W., & Galletly, D. C. (2010). Respiratory sinus arrhythmia in conscious humans during spontaneous respiration. Respiratory Physiology & Neurobiology, 174(1-3), 111-118. doi: 10.1016/j.resp.2010.04.021

Journal - Research Article

Marsland, C., Larsen, P., Segal, R., Hunter, S., Morris, J., Mezzavia, P., … Lim, W. (2010). Proficient manipulation of fibreoptic bronchoscope to carina by novices on first clinical attempt after specialized bench practice. British Journal of Anaesthesia, 104(3), 375-381. doi: 10.1093/bja/aeq005

Journal - Research Article

Robinson, S., Swain, A. H., Hoyle, S. R., & Larsen, P. D. (2010). Survival from out-of-hospital cardiac arrest in New Zealand following the 2005 resuscitation guideline changes. Resuscitation, 81(12), 1648-1651. doi: 10.1016/j.resuscitation.2010.07.009

Journal - Research Article

Sin, P. Y. W., Webber, M. R., Galletly, D. C., Ainslie, P. N., Brown, S. J., Willie, C. K., Sasse, A., Larsen, P. D., & Tzeng, Y.-C. (2010). Interactions between heart rate variability and pulmonary gas exchange efficiency in humans. Experimental Physiology, 95(7), 788-797. doi: 10.1113/expphysiol.2010.052910

Journal - Research Article

Hermiz, S., Larsen, P., Galletly, D. C., & Harding, S. A. (2009). Peri-operative management of anti-platelet agents. ANZ Journal of Surgery, 79(7-8), 521-525. doi: 10.1111/j.1445-2197.2009.04981.x

Journal - Research Article

Lever, N. A., Larsen, P. D., Dawes, M., Wong, A., & Harding, S. A. (2009). Are our medical graduates in New Zealand safe and accurate in ECG interpretation? New Zealand Medical Journal, 122(1292). Retrieved from http://journal.nzma.org.nz/journal/122-1292/3536/content.pdf

Journal - Research Article

McHale, B., Harding, S. A., Larsen, P. D., & Lever, N. A. (2009). A national survey of clinician's knowledge of and attitudes towards implantable cardioverter defibrillators. Europace, 11(10), 1313-1316. doi: 10.1093/europace/eup236

Journal - Research Article

Panfilov, I., Lever, N. A., Smaill, B. H., & Larsen, P. D. (2009). Ventricular fibrillation frequency from implanted cardioverter defibrillator devices. Europace, 11(8), 1052-1056. doi: 10.1093/europace/eup159

Journal - Research Article

Elder, D. E., Larsen, P., & Zuccollo, J. M. (2008). Failure of apnea monitoring during bed-sharing. Forensic Science, Medicine, & Pathology, 4(3), 167-169. doi: 10.1007/s12024-008-9026-z

Journal - Research Article

Mahony, P. H., Griffiths, R. F., Larsen, P., & Powell, D. (2008). Retention of knowledge and skills in first aid and resuscitation by airline cabin crew. Resuscitation, 76, 413-418. doi: 10.1016/j.resuscitation.2007.08.017

Journal - Research Article

Lever, N. A., Newall, E. G., & Larsen, P. D. (2007). Differences in the characteristics of induced and spontaneous episodes of ventricular fibrillation. Europace, 9, 1054-1058.

Journal - Research Article

Newall, E. G., Lever, N. A., Prasad, S., Hornabrook, C., & Larsen, P. D. (2007). Psychological implications of ICD implantation in a New Zealand population. Europace, 9, 20-24.

Journal - Research Article

Parnell, M. M., & Larsen, P. D. (2007). Poor quality teaching in lay person CPR courses. Resuscitation, 73, 271-278.

Journal - Research Article

Tzeng, Y. C., Larsen, P. D., & Galletly, D. C. (2007). Effects of hypercapnia and hypoxemia on respiratory sinus arrhythmia in conscious humans during spontaneous respiration. American Journal of Physiology: Heart & Circulatory Physiology, 292, H2397-H2407. doi: 10.1152/ajpheart.00817.2006

Journal - Research Article

Tzeng, Y. C., Larsen, P. D., & Galletly, D. C. (2007). Mechanism of cardioventilatory coupling: Insights from cardiac pacing, vagotomy, and sinoaortic denervation in the anesthetized rat. American Journal of Physiology: Heart & Circulatory Physiology, 292, H1967-H1977. doi: 10.1152/ajpheart.01049.2006

Journal - Research Article

Parnell, M. M., Pearson, J., Galletly, D. C., & Larsen, P. D. (2006). Knowledge of and attitudes towards resuscitation in New Zealand high-school students. Emergency Medicine Journal, 23, 899-902.

Journal - Research Article

Tanner, H., Larsen, P., Lever, N., & Galletly, D. (2006). Early recognition and early access for acute coronary syndromes in New Zealand: Key links in the chain of survival. New Zealand Medical Journal, 119(1232). Retrieved from http://journal.nzma.org.nz/journal/119-1232/1927/content.pdf

Journal - Research Article

O'Keeffe, K. M., Galletly, D. C., Miller, J. H., & Larsen, P. D. (2005). Quantal breathing frequency variation in halothane anaethetised neonatal rats. Respiratory Physiology & Neurobiology, 146(2-3), 147-153.

Journal - Research Article

Tzeng, Y.-C., Galletly, D. C., & Larsen, P. D. (2005). Paradoxical respiratory sinus arrhythmia in the anesthetized rat. Autonomic Neuroscience, 118(1-2), 25-31.

Journal - Research Article

Weller, J. M., Robinson, B. J., Jolly, B., Watterson, L. M., Joseph, M., Bajenov, S., … Larsen, P. D. (2005). Psychometric characteristics of simulation-based assessment in anaesthesia and accuracy of self-assessed scores. Anaesthesia, 60(3), 245-250.

Journal - Research Article

Williamson, L. J., Larsen, P. D., Tzeng, Y.-C., & Galletly, D. C. (2005). Effect of automatic external defibrillator audio prompts on cardiopulmonary resuscitation performance. Emergency Medicine Journal, 22(2), 140-143.

Journal - Research Article

Galletly, D., Larsen, P., Lever, N., Aickin, R., & Smith, W. (2004). Energy settings for mono- and biphasic defibrillation: Guideline of the New Zealand Resuscitation Council [Review article]. New Zealand Medical Journal, 117(1193). Retrieved from http://journal.nzma.org.nz/journal/117-1193/875/content.pdf

Journal - Research Article

Larsen, P. D., Elder, D. E., Tzeng, Y.-C., Campbell, A., & Galletly, D. C. (2004). Fractal characteristics of breath to breath timing in sleeping infants. Respiratory Physiology & Neurobiology, 139(3), 263-270.

Journal - Research Article

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