Dr Chris Coyle
| Position | Postdoctoral Fellow |
|---|---|
| Department | Department of Physiology |
| Qualifications | BSc(Hons) PGDip MSc PhD |
| Research summary | Neuroendocrine control of reproduction |
Research
My research currently focuses on the role of androgen receptor signalling within in the hypothalamus and its implications on the development of reproductive endocrinolopathies such as polycystic ovary syndrome (PCOS).
Publications
Coyle, C. S., Prescott, M., Handelsman, D. J., Walters, K. A., & Campbell, R. E. (2022). Chronic androgen excess in female mice does not impact luteinizing hormone pulse frequency or putative GABAergic inputs to GnRH neurons. Journal of Neuroendocrinology. Advance online publication. doi: 10.1111/jne.13110
Coyle, C. S., Caso, F., Tolla, E., Barrett, P., Onishi, K. G., Tello, J. A., & Stevenson, T. J. (2020). Ovarian hormones induce de novo DNA methyltransferase expression in the Siberian hamster suprachiasmatic nucleus. Journal of Neuroendocrinology, 32, e12819. doi: 10.1111/jne.12819
Coyle, C., & Campbell, R. E. (2019). Pathological pulses in PCOS. Molecular & Cellular Endocrinology, 498, 110561. doi: 10.1016/j.mce.2019.110561
Silva, M. S. B., Desroziers, E., Hessler, S., Prescott, M., Coyle, C., Herbison, A. E., & Campbell, R. E. (2019). Activation of arcuate nucleus GABA neurons promotes luteinizing hormone secretion and reproductive dysfunction: Implications for polycystic ovary syndrome. EBioMedicine, 44, 582-596. doi: 10.1016/j.ebiom.2019.05.065
