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Health Sciences profile

Dr Simone Bayer

PositionPostdoctoral Fellow
DepartmentDepartment of Medicine (Christchurch)
QualificationsPhD (Pathology)
Research summaryFunctional Gastrointestinal Disorders
MembershipsTreasurer of the New Zealand Society of Gastroenterology

Research

With a master's in Nutrition Science and a PhD in Pathology, Simone is highly interested in the complex field of Functional Gastrointestinal Disorders, specifically Irritable Bowel Syndrome (IBS), Functional Constipation (FC), and Functional Diarrhoea (FD).

She has conducted a large clinical trial on the effect of two SunGold® kiwifruit on gastrointestinal comfort and aims to analyse mRNA from colon biopsies to detect differences between FD, FC, and IBS. Furthermore, she is collaborating with Nicolas Talley from the University of Newcastle, Australia, to detect differences between these disorders through histology.

Publications

Dachs, G. U., Gandhi, J., Wohlrab, C., Carr, A. C., Morrin, H. R., Pullar, J. M., Bayer, S. B., Eglinton, T. W., Robinson, B. A., & Vissers, M. C. M. (2021). Vitamin C administration by intravenous infusion increases tumor ascorbate content in patients with colon cancer: A clinical intervention study. Frontiers in Oncology, 10, 600715. doi: 10.3389/fonc.2020.600715

Heenan, P., Creemers, R. H., Sharma, S., Keenan, J., Bayer, S., Young, W., … Skidmore, P. M., … Roy, N., Gearry, R. B., & COMFORT Cohort Collaborators. (2020). Cohort profile: The Christchurch IBS cOhort to investigate Mechanisms FOr gut Relief and improved Transit (COMFORT). Inflammatory Intestinal Diseases, 5(3), 132-143. doi: 10.1159/000508160

Heenan, P. E., Keenan, J. I., Bayer, S., Simon, M., & Gearry, R. B. (2020). Irritable bowel syndrome and the gut microbiota. Journal of the Royal Society of New Zealand, 50(3), 470-490. doi: 10.1080/03036758.2019.1695635

Pullar, J. M., Bayer, S., & Carr, A. C. (2018). Appropriate handling, processing and analysis of blood samples is essential to avoid oxidation of vitamin C to dehydroascorbic acid. Antioxidants, 7(2), 29. doi: 10.3390/antiox7020029

Bayer, S. B., Gearry, R. B., & Drummond, L. N. (2018). Putative mechanisms of kiwifruit on maintenance of normal gastrointestinal function. Critical Reviews in Food Science & Nutrition, 58(14), 2432-2452. doi: 10.1080/10408398.2017.1327841

Dachs, G. U., Gandhi, J., Wohlrab, C., Carr, A. C., Morrin, H. R., Pullar, J. M., Bayer, S. B., Eglinton, T. W., Robinson, B. A., & Vissers, M. C. M. (2021). Vitamin C administration by intravenous infusion increases tumor ascorbate content in patients with colon cancer: A clinical intervention study. Frontiers in Oncology, 10, 600715. doi: 10.3389/fonc.2020.600715

Journal - Research Article

Heenan, P., Creemers, R. H., Sharma, S., Keenan, J., Bayer, S., Young, W., … Skidmore, P. M., … Roy, N., Gearry, R. B., & COMFORT Cohort Collaborators. (2020). Cohort profile: The Christchurch IBS cOhort to investigate Mechanisms FOr gut Relief and improved Transit (COMFORT). Inflammatory Intestinal Diseases, 5(3), 132-143. doi: 10.1159/000508160

Journal - Research Article

Bayer, S. B., Gearry, R. B., & Drummond, L. N. (2018). Putative mechanisms of kiwifruit on maintenance of normal gastrointestinal function. Critical Reviews in Food Science & Nutrition, 58(14), 2432-2452. doi: 10.1080/10408398.2017.1327841

Journal - Research Article

Pullar, J. M., Bayer, S., & Carr, A. C. (2018). Appropriate handling, processing and analysis of blood samples is essential to avoid oxidation of vitamin C to dehydroascorbic acid. Antioxidants, 7(2), 29. doi: 10.3390/antiox7020029

Journal - Research Article

Carr, A. C., Rosengrave, P. C., Bayer, S., Chambers, S., Mehrtens, J., & Shaw, G. M. (2017). Hypovitaminosis C and vitamin C deficiency in critically ill patients despite recommended enteral and parenteral intakes. Critical Care, 21, 300. doi: 10.1186/s13054-017-1891-y

Journal - Research Article

Bayer, S. B., Low, F. M., Hampton, M. B., & Winterbourn, C. C. (2016). Interactions between peroxiredoxin 2, hemichrome and the erythrocyte membrane. Free Radical Research, 50(12), 1329-1339. doi: 10.1080/10715762.2016.1241995

Journal - Research Article

Bayer, S. B., Hampton, M. B., & Winterbourn, C. C. (2015). Accumulation of oxidized peroxiredoxin 2 in red blood cells and its prevention. Transfusion, 55(8), 1909-1918. doi: 10.1111/trf.13039

Journal - Research Article

Bayer, S. B., Maghzal, G., Stocker, R., Hampton, M. B., & Winterbourn, C. C. (2013). Neutrophil-mediated oxidation of erythrocyte peroxiredoxin 2 as a potential marker of oxidative stress in inflammation. FASEB Journal, 27(8), 3315-3322. doi: 10.1096/fj.13-227298

Journal - Research Article

Heenan, P. E., Keenan, J. I., Bayer, S., Simon, M., & Gearry, R. B. (2020). Irritable bowel syndrome and the gut microbiota. Journal of the Royal Society of New Zealand, 50(3), 470-490. doi: 10.1080/03036758.2019.1695635

Journal - Research Other

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