Professor David Jardine
Position | Clinical Professor |
---|---|
Department | Department of Medicine (Christchurch) |
Qualifications | BSc MBChB (Otago) DCH (Lond) FRACP |
Research summary | Sudden death |
Research
My main areas of research include sudden death, vasovagal syncope and autonomic failure in humans.Publications
Cumming, B., Frampton, C., & Jardine, D. (2022). Vasovagal syncope triggered by recent moderate weight loss? New Zealand Medical Journal, 135(1558), 10-18. Retrieved from https://journal.nzma.org.nz
Jardine, D. L., Adamson, P., & Crozier, I. G. (2022). Measuring the jugular venous pressure: Do not turn the head! American Journal of Medicine, 135(5), 552-554. doi: 10.1016/j.amjmed.2021.12.024
Jardine, D. L., Davis, J., Frampton, C. M., & Wieling, W. (2022). Sleep syncope: A prospective cohort study. Clinical Autonomic Research, 32( ), 19-27. doi: 10.1007/s10286-021-00842-1
Wieling, W., & Jardine, D. L. (2021). Efficacy of the Biosync trial: The information published from this trial to date is not sufficient to change theory. European Heart Journal, 42, 4497-4498. doi: 10.1093/eurheartj/ehab379
Weatherall, G. A., & Jardine, D. L. (2021). Pathologic U Waves secondary to severe hypophosphatemia during refeeding syndrome. JAMA Internal Medicine, 181(8), 1106-1107. doi: 10.1001/jamainternmed.2021.2233
Cumming, B., Frampton, C., & Jardine, D. (2022). Vasovagal syncope triggered by recent moderate weight loss? New Zealand Medical Journal, 135(1558), 10-18. Retrieved from https://journal.nzma.org.nz
Journal - Research Article
Jardine, D. L., Davis, J., Frampton, C. M., & Wieling, W. (2022). Sleep syncope: A prospective cohort study. Clinical Autonomic Research, 32( ), 19-27. doi: 10.1007/s10286-021-00842-1
Journal - Research Article
Weatherall, G. A., & Jardine, D. L. (2021). Pathologic U Waves secondary to severe hypophosphatemia during refeeding syndrome. JAMA Internal Medicine, 181(8), 1106-1107. doi: 10.1001/jamainternmed.2021.2233
Journal - Research Article
Wieling, W., & Jardine, D. L. (2021). Efficacy of the Biosync trial: The information published from this trial to date is not sufficient to change theory. European Heart Journal, 42, 4497-4498. doi: 10.1093/eurheartj/ehab379
Journal - Research Article
Al-Busaidi, I. S., & Jardine, D. L. (2020). Different types of syncope presenting to clinic: Do we miss cardiac syncope? Heart, Lung & Circulation, 29, 1129-1138. doi: 10.1016/j.hlc.2019.09.008
Journal - Research Article
Charles, C. J., Jardine, D. L., Rademaker, M. T., & Richards, A. M. (2019). Adrenomedullin 2 increases cardiac sympathetic nerve activity in parallel to heart rate in normal conscious sheep. Physiological Reports, 7(10), e14096. doi: 10.14814/phy2.14096
Journal - Research Article
Charles, C. J., Jardine, D. L., Rademaker, M. T., & Richards, A. M. (2018). Systemic Angiotensin II does not increase cardiac sympathetic nerve activity in normal conscious sheep. Bioscience Reports, 38(5), BSR20180513. doi: 10.1042/bsr20180513
Journal - Research Article
Jardine, D. L., Wieling, W., Brignole, M., Lenders, J. W. M., Sutton, R., & Stewart, J. (2018). The pathophysiology of the vasovagal response. Heart Rhythm, 15(6), 921-929. doi: 10.1016/j.hrthm.2017.12.013
Journal - Research Article
Slow, S., Epton, M., Storer, M., Thiessen, R., Lim, S., Wong, J., Chin, P., Tovaranonte, P., Pearson, J., Chambers, S. T., Murdoch, D. R., and VIDCAPS Group, including Jardine, D., & Pithie, A. (2018). Effect of adjunctive single high-dose vitamin D3 on outcome of community-acquired pneumonia in hospitalised adults: The VIDCAPS randomised controlled trial. Scientific Reports, 8(1), 13829. doi: 10.1038/s41598-018-32162-2
Journal - Research Article
Hoye, N. A., Wilson, L. C., Wilkins, G. T., Jardine, D. L., Putt, T. L., Samaranayaka, A., Schollum, J. B. W., & Walker, R. J. (2017). Endovascular renal denervation in end-stage kidney disease patients: Cardiovascular protection: A proof-of-concept study. Kidney International Reports, 2(5), 856-865. doi: 10.1016/j.ekir.2017.04.012
Journal - Research Article
Jardine, D. L., McKenzie, J. M., & Wilkinson, T. J. (2017). Predicting medical students who will have difficulty during their clinical training. BMC Medical Education, 17, 43. doi: 10.1186/s12909-017-0879-2
Journal - Research Article
Stewart, J. M., Medow, M. S., Sutton, R., Visintainer, P., Jardine, D. L., & Wieling, W. (2017). Mechanisms of vasovagal syncope in the young: Reduced systemic vascular resistance versus reduced cardiac output. Journal of the American Heart Association, 6(1), e004417. doi: 10.1161/jaha.116.004417
Journal - Research Article
Than, M. P., Pickering, J. W., Aldous, S. J., Cullen, L., Frampton, C. M. A., Peacock, W. F., … Richards, A. M., Ardagh, M. W., Deely, J. M., Florkowski, C. M., George, P., Hamilton, G. J., Jardine, D. L., Troughton, R. W., … Lord, S. J. (2016). Effectiveness of EDACS versus ADAPT accelerated diagnostic pathways for chest pain: A pragmatic randomized controlled trial embedded within practice. Annals of Emergency Medicine, 68(1), 93-102. doi: 10.1016/j.annemergmed.2016.01.001
Journal - Research Article
Chan, W. Y. W., Charles, C. J., Frampton, C. M., Richards, A. M., Crozier, I. G., Troughton, R. W., & Jardine, D. L. (2015). Human muscle sympathetic nerve responses to urocortin-2 in health and stable heart failure. Clinical & Experimental Pharmacology & Physiology, 42(9), 888-895. doi: 10.1111/1440-1681.12449
Journal - Research Article
Chieng, J. H. C., Hughes, L., Stewart, A., Frampton, C. M., Hanger, H. C., & Jardine, D. L. (2015). Introduction of the Pill Pruner to acute medical care: A simple medication guide to control polypharmacy. Australasian Journal on Ageing, 34(1), 58-61. doi: 10.1111/ajag.12183
Journal - Research Article
Wieling, W., Jardine, D. L., de Lange, F. J., Brignole, M., Nielsen, H. B., Stewart, J., & Sutton, R. (2015). Cardiac output and vasodilatation in the vasovagal response: An analysis of the classical papers. Heart Rhythm, 13(3), 798-805. doi: 10.1016/j.hrthm.2015.11.023
Journal - Research Article
Charles, C. J., Jardine, D. L., Rademaker, M. T., & Richards, A. M. (2014). Low-dose B-type natriuretic peptide raises cardiac sympathetic nerve activity in sheep. American Journal of Physiology: Regulatory, Integrative & Comparative Physiology, 307(2), R206-R211. doi: 10.1152/ajpregu.00404.2013
Journal - Research Article
McLachlan, C. Y. L., Yi, M., Ling, A., & Jardine, D. L. (2014). Adverse drug events are a major cause of acute medical admission. Internal Medicine Journal, 44(7), 633-638. doi: 10.1111/imj.12455
Journal - Research Article
Spencer, A., Cawood, T., Frampton, C., & Jardine, D. (2014). Heparin-based treatment to prevent symptomatic deep venous thrombosis, pulmonary embolism or death in general medical inpatients is not supported by best evidence. Internal Medicine Journal, 44(11), 1054-1065. doi: 10.1111/imj.12574
Journal - Research Article
Than, M., Aldous, S., Lord, S. J., Goodacre, S., Frampton, C. M. A., Troughton, R., George, P., Florkowski, C. M., Ardagh, M., Smyth, D., Jardine, D. L., … Young, J., Hamilton, G., Deely, J. M., … Richards, A. M. (2014). A 2-hour diagnostic protocol for possible cardiac chest pain in the emergency department: A randomized clinical trial. JAMA Internal Medicine, 174(1), 51-58. doi: 10.1001/jamainternmed.2013.11362
Journal - Research Article
Jardine, D. L. (2013). Vasovagal syncope: New physiologic insights. Cardiology Clinics, 31(1), 75-87. doi: 10.1016/j.ccl.2012.10.010
Journal - Research Article
Wieling, W., Krediet, C. T. P., Solari, D., de Lange, F. J., van Dijk, N., Thijs, R. D., … Jardine, D. L. (2013). At the heart of the arterial baroreflex: A physiological basis for a new classification of carotid sinus hypersensitivity. Journal of Internal Medicine, 273(4), 345-358. doi: 10.1111/joim.12042
Journal - Research Article
Jensen, B. P., Roberts, R. L., Vyas, R., Bonke, G., Jardine, D. L., & Begg, E. J. (2012). Influence of ABCB1 (P-glycoprotein) haplotypes on nortriptyline pharmacokinetics and nortriptyline-induced postural hypotension in healthy volunteers. British Journal of Clinical Pharmacology, 73(4), 619-628. doi: 10.1111/j.1365-2125.2011.04126.x
Journal - Research Article
Rozenberg, J., Wieling, W., Schon, I. K., Westerhof, B., Frampton, C., & Jardine, D. (2012). MSNA during prolonged post-faint hypotension. Clinical Autonomic Research, 22(4), 167-173. doi: 10.1007/s10286-012-0159-5
Journal - Research Article
Charles, C. J., Jardine, D. L., Rademaker, M. T., & Richards, M. (2011). Urocortin 3 inhibits cardiac sympathetic nerve activity in conscious sheep. Journal of Cardiovascular Pharmacology, 58(4), 418-423. doi: 10.1097/FJC.0b013e31822707a4
Journal - Research Article
Krediet, C. T. P., Jardine, D. L., & Wieling, W. (2011). Dissection of carotid sinus hypersensitivity: The timing of vagal and vasodepressor effects and the effect of body position. Clinical Science, 121, 389-396. doi: 10.1042/cs20100607
Journal - Research Article
Krediet, C. T. P., Parry, S. W., Jardine, D. L., Benditt, D. G., Brignole, M., & Wieling, W. (2011). The history of diagnosing carotid sinus hypersensitivity: Why are the current criteria too sensitive? Europace, 13(1), 14-22. doi: 10.1093/europace/euq409
Journal - Research Article
Wieling, W., Rozenberg, J., Go-Schön, I. K., Karemaker, J. M., Westerhof, B. E., & Jardine, D. L. (2011). Hemodynamic mechanisms underlying prolonged post-faint hypotension. Clinical Autonomic Research, 21(6), 405-413. doi: 10.1007/s10286-011-0134-6
Journal - Research Article
Busweiler, L., Jardine, D. L., Frampton, C. M., & Wieling, W. (2010). Sleep syncope: Important clinical associations with phobia and vagotonia. Sleep Medicine, 11(9), 929-933. doi: 10.1016/j.sleep.2010.04.013
Journal - Research Article
Charles, C. J., Jardine, D. L., Rademaker, M. T., & Richards, A. M. (2010). Urocortin 2 induces potent long-lasting inhibition of cardiac sympathetic drive despite baroreflex activation in conscious sheep. Journal of Endocrinology, 204, 181-189. doi: 10.1677/JOE-08-0505
Journal - Research Article
Jardine, D. L., Krediet, C. T. P., Cortelli, P., Frampton, C. M., & Wieling, W. (2009). Sympatho-vagal responses in patients with sleep and typical vasovagal syncope. Clinical Science, 117, 345-353. doi: 10.1042/CS20080497
Journal - Research Article
Charles, C. J., Jardine, D. L., Nicholls, M. G., Rademaker, M. T., & Richards, A. M. (2008). Urocortin 1 exhibits potent inhibition of cardiac sympathetic nerve activity in conscious sheep. Journal of Hypertension, 26(1), 53-60.
Journal - Research Article
Jardine, D. L., Charles, C. J., Frampton, C. M., & Richards, A. M. (2007). Cardiac sympathetic nerve activity and ventricular fibrillation during acute myocardial infarction in a conscious sheep model. American Journal of Physiology: Heart & Circulatory Physiology, 293, H433-H439. doi: 10.1152/ajpheart.01262.2006
Journal - Research Article
Charles, C. J., Jardine, D. L., Nicholls, M. G., & Richards, A. M. (2005). Adrenomedullin increases cardiac sympathetic nerve activity in normal conscious sheep. Journal of Endocrinology, 187, 275-281.
Journal - Research Article
Jardine, D. L., Charles, C. J., Ashton, R. K., Bennett, S. I., Whitehead, M., Frampton, C. M., & Nicholls, M. G. (2005). Increased cardiac sympathetic nerve activity following acute myocardial infarction in a sheep model. Journal of Physiology, 565(1), 325-333. doi: 10.1113/jphysiol.2004.082198
Journal - Research Article
Griffith, J. C., Jardine, D. L., Bailey, W., & Florkowski, C. M. (2004). Variegate porphyria presenting with acute autonomic dysfunction, intussusception and renal infarction. Scandinavian Journal of Gastroenterology, 39(5), 500-503. doi: 10.1080/00365520410008395
Journal - Research Article
Jardine, D. L., Krediet, C. T. P., & Robinson, B. A. (2004). Baroreflex failure secondary to paraneoplastic encephalomyelitis in a 17 year old woman with neuroblastoma. Journal of Neurology, Neurosurgery & Psychiatry, 75, 1650-1651.
Journal - Research Article
Krediet, C. T. P., Jardine, D. L., Cortelli, P., Visman, A. G. R., & Wieling, W. (2004). Vasovagal syncope interrupting sleep? Heart, 90(e25). Retrieved from http://www.heartjnl.com/cgi/content/full/90/5/e25/
Journal - Research Article
Jardine, D., Charles, C. J., Forrester, M. D., Whitehead, M., & Nicholls, M. G. (2003). A neural mechanism for sudden death after myocardial infarction. Clinical Autonomic Research, 13, 339-341.
Journal - Research Article
Jardine, D., Hurrell, M., & Anderson, T. J. (2003). A bad dose of the 'flu. Lancet, 362, 1198.
Journal - Research Article
Tang, E. W., Jardine, D., Rodins, K., & Evans, J. (2003). Respiratory failure secondary to diabetic neuropathy affecting the phrenic nerve. Diabetic Medicine, 20, 599-601.
Journal - Research Article
Jardine, D., & Colls, B. M. (2002). Hodgkins's disease following methotrexate therapy for rheumatoid arthritis. New Zealand Medical Journal, 115, 293-294.
Journal - Research Article
Jardine, D., Charles, C. J., Melton, I., May, C. N., Forrester, M. D., Frampton, C. M., … Ikram, H. (2002). Continual recordings of cardiac sympathetic nerve activity in conscious sheep. American Journal of Physiology: Heart & Circulatory Physiology, 282, H93-H99.
Journal - Research Article
Jardine, D., Melton, I., Crozier, I., English, S., Bennett, S. I., Frampton, C. M., & Ikram, H. (2002). Decrease in cardiac output and muscle sympathetic activity during vasovagal syncope. American Journal of Physiology: Heart & Circulatory Physiology, 282, H1804-H1809.
Journal - Research Article
Jardine, D. L., Crozier, I. G., & Ikram, H. (2001). Paroxysmal hypertension during a complex partial seizure. Journal of Neurology, Neurosurgery & Psychiatry, 71, 129-137.
Journal - Research Article
Jardine, D. L., Davis, P. J., Robert, A., Lamont, D. L., & Wilton, G. N. (2001). Spontaneous cholesterol embolization complicated by pulmonary fat embolism. Internal Medicine Journal, 31, 319-320.
Journal - Research Article
McGregor, D. O., Buttimore, A. L., Lynn, K. L., Nicholls, M. G., & Jardine, D. L. (2001). A comparative study of blood pressure control with short in-center versus long home hemodialysis. Blood Purification, 19, 293-300.
Journal - Research Article
Grayling, M., Jardine, D. L., McClintock, A. D., Spar, J., & Wilton, G. N. (2000). Symptomatic epidural lipomatosis following cyproterone acetate therapy. Australian & New Zealand Journal of Surgery, 70, 233-235.
Journal - Research Article
Jardine, D., Melton, I., Bennett, S. I., Crozier, I. G., Donaldson, I. M., & Ikram, H. (2000). Baroreceptor denervation presenting as part of a vagal mononeuropathy. Clinical Autonomic Research, 10, 69-75.
Journal - Research Article
Phillips, A. M., Jardine, D., Parkin, P. J., Hughes, T. H., & Ikram, H. (2000). Brainstem stroke causing baroreflex failure and paroxysmal hypertension. Stroke, 31, 1997-2001.
Journal - Research Article
Jardine, D. L., Melton, I. C., Crozier, I. G., Bennett, S. L., Donald, R. A., & Ikram, H. (1997). Neurohormonal response to head-up tilt and its role in vasovagal syncope. American Journal of Cardiology, 79(9), 1302-1306.
Journal - Research Article
Jardine, D. L., Adamson, P., & Crozier, I. G. (2022). Measuring the jugular venous pressure: Do not turn the head! American Journal of Medicine, 135(5), 552-554. doi: 10.1016/j.amjmed.2021.12.024
Journal - Research Other
de Jong, J. S. Y., Jardine, D. L., Lenders, J. W. M., & Wieling, W. (2019). Pacing in vasovagal syncope: A physiological paradox? Heart Rhythm, 17(5A), 813-820. doi: 10.1016/j.hrthm.2019.09.022
Journal - Research Other
Dhayalan, S., Jardine, D., Goh, T., & Lash, N. (2019). Acute compartment syndrome complicating deep venous thrombosis. New Zealand Medical Journal, 132(1493), 73-76. Retrieved from https://www.nzma.org.nz/journal
Journal - Research Other
Hoye, N. A., Wilson, L. C., Jardine, D. L., & Walker, R. J. (2019). Sympathetic overactivity in dialysis patients: Underappreciated and clinically consequential. Seminars in Dialysis, 32, 255-265. doi: 10.1111/sdi.12756
Journal - Research Other
Wieling, W., de Lange, F. J., & Jardine, D. L. (2014). The heart cannot pump blood that it does not receive. Frontiers in Physiology, 5, 360. doi: 10.3389/fphys.2014.00360
Journal - Research Other
Wong, J., Miller, A., Cross, N., Grundy, K., O'Keefe, M., & Jardine, D. (2014). Calciphylaxis: Fatal arteriosclerosis of uncertain mechanism. Internal Medicine Journal, 44(10), 1040-1041. doi: 10.1111/imj.12562
Journal - Research Other
Betteridge, T. M., Frampton, C. M., & Jardine, D. L. (2012). Polypharmacy: We make it worse! A cross-sectional study from an acute admissions unit [Brief communication]. Internal Medicine Journal, 42(2), 208-211. doi: 10.1111/j.1445-5994.2011.02690.x
Journal - Research Other
McNally, A., Pithie, A., & Jardine, D. (2012). Cefepime: A rare cause of encephalopathy. Internal Medicine Journal, 42(6), 732-733. doi: 10.1111/j.1445-5994.2012.02800.x
Journal - Research Other
Wieling, W., Rozenberg, J., Schon, I. K., Karemaker, J. M., Westerhof, B. E., & Jardine, D. L. (2011). Prolonged post-faint hypotension can be reversed by dynamic tension. Clinical Autonomic Research, 21(6), 415-418. doi: 10.1007/s10286-011-0133-7
Journal - Research Other
Huelsen-Katz, A. M., Schouten, B. J., Jardine, D. L., Soule, S. G., & Liu, H. (2010). Pictorial evolution of bilateral adrenal haemorrhage [Letter to the editor]. Internal Medicine Journal, 40(1), 87-88. doi: 10.1111/j.1445-5994.2009.02117.x
Journal - Research Other
Chen, H. K., Jardine, D., & Beckert, L. (2009). Orthopnoea and arm weakness. Thorax, 64(12), 1031. doi: 10.1136/thx.2009.121632
Journal - Research Other
Macdonald, C. A., Jardine, D. L., Hurrell, M. A., & Pithie, A. D. (2009). The worm that turned [Case report]. Transactions of the Royal Society of Tropical Medicine & Hygiene, 103(10), 1065-1067. doi: 10.1016/j.trstmh.2009.05.007
Journal - Research Other
Hutchinson, C. D., Jardine, D. L., & Hurrell, M. (2008). Vagolysis [Case report]. Age & Ageing, 37, 602-604. doi: 10.1093/ageing/afn105
Journal - Research Other
Jardine, D. L., Hurrell, M. A., & Fink, J. (2007). Tilt-test diagnosis of hypotensive transient ischaemic attacks. Internal Medicine Journal, 37(7), 498-501.
Journal - Research Other
Jardine, D. L., & Laing, A. D. (2004). Delayed pulmonary hypertension following splenectomy for congenital spherocytosis [Clinical-scientific note]. Internal Medicine Journal, 34(4), 214-216.
Journal - Research Other
Archibald, N., Dalzell, K. G. B., Fernando, C., & Jardine, D. (2003). Infectious mononucleosis complicated by mediastinal lymphadenopathy causing transient pulmonary artery stenosis [Letter to the editor]. Internal Medicine Journal, 33(7), 324-325. doi: 10.1046/j.1445-5994.2003.00409.x
Journal - Research Other