Accessibility Skip to Global Navigation Skip to Local Navigation Skip to Content Skip to Search Skip to Site Map Menu

Health Sciences profile

Professor Paul Glue

PositionHazel Buckland Professor; Division of Health Sciences Associate Dean (Research Commercialisation)
DepartmentDepartment of Psychological Medicine (Dunedin)
QualificationsMB ChB(Otago) MD(Bristol) MRCPsych
Research summaryPsychological Medicine

Research

  • Psychopharmacology
  • Pharmacokinetics/Pharmacodynamics
  • Clinical Trial Design
  • Translational Medicine
  • Clinical Pharmacology

Development of novel therapeutics for affective disorders and learning disorders Biomarkers in anxiety.

Professor Glue's research focuses on clinical and basic science. His areas of interest include the pharmacology of drug treatments in psychiatry and the investigation of disease mechanisms in neurological and psychiatric disorders. He is also interested in technical aspects of clinical trial design, including trialling simulation and modelling. He has published extensively, with more than 250 papers and book chapters to his name.

Publications

Shadli, S. M., Ando, L. C., McIntosh, J., Lodhia, V., Russell, B. R., Kirk, I. J., Glue, P., & McNaughton, N. (2021). Right frontal anxiolytic-sensitive EEG 'theta' rhythm in the stop-signal task is a theory-based anxiety disorder biomarker. Scientific Reports, 11, 19746. doi: 10.1038/s41598-021-99374-x

Peng, M., Potterton, H., Chu, J. T. W., & Glue, P. (2021). Olfactory shifts linked to postpartum depression. Scientific Reports, 11(1), 14947. doi: 10.1038/s41598-021-94556-z

Perez, T. M., Glue, P., Adhia, D. B., Mathew, J., & De Ridder, D. (2021). Is there evidence for EEG-neurofeedback specificity in the treatment of internalizing disorders? A protocol for a systematic review and meta-analysis. NeuroRegulation, 8(1), 22-28. doi: 10.15540/nr.8.1.22

Barak, Y., Barson, D., Davie, G., Glue, P., & Paleacu, D. (2021). Internalize at your peril: Internalizing disorders as risk factors for dementia: Cohort study. GeroScience, 43, 253-261. doi: 10.1007/s11357-020-00285-y

Lenagh-Glue, J., Potiki, J., O'Brien, A., Dawson, J., Thom, K., Casey, H., & Glue, P. (2021). Help and hindrances to completion of psychiatric advance directives. Psychiatric Services, 72(2), 216-218. doi: 10.1176/appi.ps.202000080

De Ridder, D., Manning, P., Cape, G., Vanneste, S., Langguth, B., & Glue, P. (2016). Pathophysiology-based neuromodulation for addictions: An overview. In V. R. Preedy (Ed.), Neuropathology of drug addictions and substance misuse (Vol. 1: Foundations of understanding, tobacco, alcohol, cannabinoids and opioids). (pp. 14-24). London: Elsevier. doi: 10.1016/B978-0-12-800213-1.00002-X

Chapter in Book - Research

Dawson, J., Ellis, P., Glue, P., Goldsmith, D., Lenagh-Glue, J., & Smith, D. A. R. (2013). Mandatory second opinions on compulsory treatment. In J. Dawson & K. Gledhill (Eds.), New Zealand's Mental Health Act in practice. (pp. 229-246). Wellington, New Zealand: Victoria University Press.

Chapter in Book - Research

Barak, Y., Barson, D., Davie, G., Glue, P., & Paleacu, D. (2021). Internalize at your peril: Internalizing disorders as risk factors for dementia: Cohort study. GeroScience, 43, 253-261. doi: 10.1007/s11357-020-00285-y

Journal - Research Article

Barak, Y., Leitch, S., & Glue, P. (2021). The Great Escape: Centenarians' exceptional health. Aging Clinical & Experimental Research, 33(3), 513-520. doi: 10.1007/s40520-020-01552-w

Journal - Research Article

Neumann, S. R., Glue, P., & Linscott, R. J. (2021). Aberrant salience and reward processing: A comparison of measures in schizophrenia and anxiety. Psychological Medicine, 51, 1507-1515. doi: 10.1017/s0033291720000264

Journal - Research Article

Peng, M., Potterton, H., Chu, J. T. W., & Glue, P. (2021). Olfactory shifts linked to postpartum depression. Scientific Reports, 11(1), 14947. doi: 10.1038/s41598-021-94556-z

Journal - Research Article

Shadli, S. M., Ando, L. C., McIntosh, J., Lodhia, V., Russell, B. R., Kirk, I. J., Glue, P., & McNaughton, N. (2021). Right frontal anxiolytic-sensitive EEG 'theta' rhythm in the stop-signal task is a theory-based anxiety disorder biomarker. Scientific Reports, 11, 19746. doi: 10.1038/s41598-021-99374-x

Journal - Research Article

Truppman Lattie, D., Nehoff, H., Neehoff, S., Gray, A., & Glue, P. (2021). Anxiolytic effects of acute and maintenance ketamine, as assessed by the Fear Questionnaire subscales and the Spielberger State Anxiety Rating Scale. Journal of Psychopharmacology, 35(2), 137-141. doi: 10.1177/0269881120953991

Journal - Research Article

Barak, Y., Cheung, G., Fortune, S., & Glue, P. (2020). No country for older men: Ageing male suicide in New Zealand. Australasian Psychiatry, 28(4), 383-385. doi: 10.1177/1039856220905304

Journal - Research Article

Barak, Y., Neehoff, S., & Glue, P. (2020). Ageing badly: Indicators of old-age structure in Australia and New Zealand. Journal of Primary Health Care, 12(3), 272-276. doi: 10.1071/hc19095

Journal - Research Article

Glue, P., Medlicott, N. J., Neehoff, S., Surman, P., Lam, F., Hung, N., & Hung, C.-T. (2020). Safety and efficacy of extended release ketamine tablets in patients with treatment-resistant depression and anxiety: Open label pilot study. Therapeutic Advances in Psychopharmacology, 10, 1-6. doi: 10.1177/2045125320922474

Journal - Research Article

Glue, P., Medlicott, N. J., Surman, P., Lam, F., Hung, N., & Hung, C. T. (2020). Ascending-dose study of controlled-release ketamine tablets in healthy volunteers: Pharmacokinetics, pharmacodynamics, safety, and tolerability. Journal of Clinical Pharmacology, 60(6), 751-757. doi: 10.1002/jcph.1573

Journal - Research Article

Glue, P., Neehoff, S., Sabadel, A., Broughton, L., Le Nedelec, M., Shadli, S., McNaughton, N., & Medlicott, N. J. (2020). Effects of ketamine in patients with treatment-refractory generalized anxiety and social anxiety disorders: Exploratory double-blind psychoactive-controlled replication study. Journal of Psychopharmacology, 34(3), 267-272. doi: 10.1177/0269881119874457

Journal - Research Article

Lenagh-Glue, J., Thom, K., O'Brien, A., Potiki, J., Casey, H., Dawson, J., & Glue, P. (2020). The content of Mental Health Advance Preference statements (MAPs): An assessment of completed advance directives in one New Zealand health board. International Journal of Law & Psychiatry, 68, 101537. doi: 10.1016/j.ijlp.2019.101537

Journal - Research Article

Leong, S. L., Glue, P., Manning, P., Vanneste, S., Lim, L. J., Mohan, A., & De Ridder, D. (2020). Anterior cingulate cortex implants for alcohol addiction: A feasibility study. Neurotherapeutics, 17, 1287-1299. doi: 10.1007/s13311-020-00851-4

Journal - Research Article

Shadli, S. M., High, O., Byers, B., Gibbs, P., Steller, R., Glue, P., & McNaughton, N. (2020). Human anxiety-specific "theta" occurs with selective stopping and localizes to right inferior frontal gyrus. Behavioral Neuroscience, 134(6), 547-555. doi: 10.1037/bne0000316

Journal - Research Article

Short, B., Dong, V., Gálvez, V., Vulovic, V., Martin, D., Bayes, A. J., … Glue, P., … Loo, C. K. (2020). Development of the Ketamine Side Effect Tool (KSET). Journal of Affective Disorders, 266, 615-620. doi: 10.1016/j.jad.2020.01.120

Journal - Research Article

Allwood, C., O'Brien, A., & Glue, P. (2019). Referrals from primary care to community mental health teams: What's missing? Journal of Primary Health Care, 11(4), 334-341. doi: 10.1071/HC19053

Journal - Research Article

Gale, C., Glue, P., Guaiana, G., Coverdale, J., McMurdo, M., & Wilkinson, S. (2019). Influence of covariates on heterogeneity in Hamilton Anxiety Scale ratings in placebo-controlled trials of benzodiazepines in generalized anxiety disorders: Systematic review and meta-analysis. Journal of Psychopharmacology, 33(5), 543-547. doi: 10.1177/0269881118822146

Journal - Research Article

Thom, K., Lenagh-Glue, J., O'Brien, A. J., Potiki, J., Casey, H., Dawson, J., & Glue, P. (2019). Service user, whānau and peer support workers' perceptions of advance directives for mental health. International Journal of Mental Health Nursing, 28, 1296-1305. doi: 10.1111/inm.12637

Journal - Research Article

Glue, P., Neehoff, S. M., Medlicott, N. J., Gray, A., Kibby, G., & McNaughton, N. (2018). Safety and efficacy of maintenance ketamine treatment in patients with treatment-refractory generalised anxiety and social anxiety disorders. Journal of Psychopharmacology, 32(6), 663-667. doi: 10.1177/0269881118762073

Journal - Research Article

Gálvez, V., Li, A., Huggins, C., Glue, P., Martin, D., Somogyi, A. A., … Loo, C. K. (2018). Repeated intranasal ketamine for treatment-resistant depression: The way to go? Results from a pilot randomised controlled trial. Journal of Psychopharmacology, 32(4), 397-407. doi: 10.1177/0269881118760660

Journal - Research Article

Le Nedelec, M., Glue, P., Winter, H., Goulton, C., & Medlicott, N. J. (2018). The effect of route of administration on the enantioselective pharmacokinetics of ketamine and norketamine in rats. Journal of Psychopharmacology, 32(10), 1127-1132. doi: 10.1177/0269881118780013

Journal - Research Article

Le Nedelec, M., Glue, P., Winter, H., Goulton, C., Broughton, L., & Medlicott, N. (2018). Acute low-dose ketamine produces a rapid and robust increase in plasma BDNF without altering brain BDNF concentrations. Drug Delivery & Translational Research, 8(3), 780-786. doi: 10.1007/s13346-017-0476-2

Journal - Research Article

Leitch, S., Glue, P., Gray, A. R., Greco, P., & Barak, Y. (2018). Comparison of psychosocial variables associated with loneliness in centenarian vs elderly populations in New Zealand. JAMA Network Open, 1(6), e183880. doi: 10.1001/jamanetworkopen.2018.3880

Journal - Research Article

Lenagh-Glue, J., O'Brien, A., Dawson, J., Thom, K., Potiki, J., Casey, H., & Glue, P. (2018). A MAP to mental health: The process of creating a collaborative advance preferences instrument. New Zealand Medical Journal, 131(1486), 18-26. Retrieved from https://www.nzma.org.nz/journal

Journal - Research Article

Menkes, D. B., Glue, P., Gale, C., Lam, F., Hung, C.-T., & Hung, N. (2018). Steady-state clozapine and norclozapine pharmacokinetics in Maori and European patients. EBioMedicine, 27, 134-137. doi: 10.1016/j.ebiom.2017.11.030

Journal - Research Article

Shadli, S. M., Kawe, T., Martin, D., McNaughton, N., Neehoff, S., & Glue, P. (2018). Ketamine effects on EEG during therapy of treatment-resistant generalized anxiety and social anxiety. International Journal of Neuropsychopharmacology, 21(8), 717-724. doi: 10.1093/ijnp/pyy032

Journal - Research Article

Castle, C., Gray, A., Neehoff, S., & Glue, P. (2017). Effect of ketamine dose on self-rated dissociation in patients with treament refractory anxiety disorders. Journal of Psychopharmacology, 31(10), 1306-1311. doi: 10.1177/0269881117725685

Journal - Research Article

George, D., Gálvez, V., Martin, D., Kumar, D., Leyden, J., Hadzi-Pavlovic, D., … Glue, P., … Loo, C. K. (2017). Pilot randomized controlled trial of titrated subcutaneous ketamine in older patients with treatment-resistant depression. American Journal of Geriatric Psychiatry, 25(11), 1199-1209. doi: 10.1016/j.jagp.2017.06.007

Journal - Research Article

Glue, P., Medlicott, N. J., Harland, S., Neehoff, S., Anderson-Fahey, B., Le Nedelec, M., Gray, A., & McNaughton, N. (2017). Ketamine's dose-related effects on anxiety symptoms in patients with treatment refractory anxiety disorders. Journal of Psychopharmacology, 31(10), 1302-1305. doi: 10.1177/0269881117705089

Journal - Research Article

Courts, J., Maskill, V., Gray, A., & Glue, P. (2016). Signs and symptoms associated with synthetic cannabinoid toxicity: Systematic review. Australasian Psychiatry, 24(6), 598-601. doi: 10.1177/1039856216663733

Journal - Research Article

De Ridder, D., Vanneste, S., Gillett, G., Manning, P., Glue, P., & Langguth, B. (2016). Psychosurgery reduces uncertainty and increases free will? A review. Neuromodulation, 19, 239-248. doi: 10.1111/ner.12405

Journal - Research Article

Forsyth, B., Machado, L., Jowett, T., Jakobi, H., Garbe, K., Winter, H., & Glue, P. (2016). Effects of low dose ibogaine on subjective mood state and psychological performance. Journal of Ethnopharmacology, 189, 10-13. doi: 10.1016/j.jep.2016.05.022

Journal - Research Article

French, J., Glue, P., Friedman, D., Almas, M., Yardi, N., Knapp, L., … Posner, H. B. (2016). Adjunctive pregabalin vs gabapentin for focal seizures: Interpretation of comparative outcomes. Neurology, 87(12), 1242-1249. doi: 10.1212/wnl.0000000000003118

Journal - Research Article

Glue, P., Cape, G., Tunnicliff, D., Lockhart, M., Lam, F., Gray, A., Hung, N., … Harland, S., … Friedhoff, L. (2016). Switching opioid-dependent patients from methadone to morphine: Safety, tolerability, and methadone pharmacokinetics. Journal of Clinical Pharmacology, 56(8), 960-965. doi: 10.1002/jcph.704

Journal - Research Article

Glue, P., Cape, G., Tunnicliff, D., Lockhart, M., Lam, F., Hung, N., … Harland, S., … Friedhoff, L. (2016). Ascending single-dose, double-blind, placebo-controlled safety study of noribogaine in opioid-dependent patients. Clinical Pharmacology in Drug Development, 5(6), 460-468. doi: 10.1002/cpdd.254

Journal - Research Article

Glue, P., Courts, J., Gray, A., & Patterson, T. (2016). Influence of law changes affecting synthetic cannabinoid availability and frequency of hospital presentations: 4-year national survey. New Zealand Medical Journal, 129(1433), 41-44. Retrieved from http://www.nzma.org.nz/journal

Journal - Research Article

Loo, C. K., Gálvez, V., O'Keefe, E., Mitchell, P. B., Hadzi-Pavlovic, D., Leyden, J., … Glue, P. (2016). Placebo-controlled pilot trial testing dose titration and intravenous, intramuscular and subcutaneous routes for ketamine in depression. Acta Psychiatrica Scandinavica, 134(1), 48-56. doi: 10.1111/acps.12572

Journal - Research Article

Shadli, S. M., Smith, M. J., Glue, P., & McNaughton, N. (2016). Testing an anxiety process biomarker: Generalisation from an auditory to a visual stimulus. Biological Psychology, 117, 50-55. doi: 10.1016/j.biopsycho.2016.02.011

Journal - Research Article

Whigham, P. A., de Graaf, B., Srivastava, R., & Glue, P. (2016). Managing distance and covariate information with point-based clustering. BMC Medical Research Methodology, 16(1), 115. doi: 10.1186/s12874-016-0218-z

Journal - Research Article

Xu, Y., Hackett, M., Carter, G., Loo, C., Gálvez, V., Glozier, N., Glue, P., … Rodgers, A. (2016). Effects of low-dose and very low-dose ketamine among patients with major depression: A systematic review and meta-analysis. International Journal of Neuropsychopharmacology, 19(4), 1-15. doi: 10.1093/ijnp/pyv124

Journal - Research Article

Dawson, J., Glue, P., Ellis, P. M., Lenagh-Glue, J., Goldsmith, D., & Smith, D. A. R. (2015). Lessons from export to New Zealand of the second opinion appointed doctor scheme. BJPsych Bulletin, 39(2), 69-73. doi: 10.1192/pb.bp.113.046540

Journal - Research Article

Glue, P., & Herbison, P. (2015). Comparative efficacy and acceptability of combined antipsychotics and mood stabilizers versus individual drug classes for acute mania: Network meta-analysis. Australian & New Zealand Journal of Psychiatry, 49(12), 1215-1220. doi: 10.1177/0004867415614109

Journal - Research Article

Glue, P., Courts, J., Gale, C., & Mason, E. (2015). Implementation of the 2013 Psychoactive Substances Act and mental health harms from synthetic cannabinoids. New Zealand Medical Journal, 128(1414). Retrieved from https://www.nzma.org.nz/journal

Journal - Research Article

Glue, P., Lockhart, M., Lam, F., Hung, N., Hung, C.-T., & Friedhoff, L. (2015). Ascending-dose study of noribogaine in healthy volunteers: Pharmacokinetics, pharmacodynamics, safety, and tolerability. Journal of Clinical Pharmacology, 55(2), 189-194. doi: 10.1002/jcph.404

Journal - Research Article

Glue, P., Winter, H., Garbe, K., Jakobi, H., Lyudin, A., Lenagh-Glue, Z., & Hung, C. T. (2015). Influence of CYP2D6 activity on the pharmacokinetics and pharmacodynamics of a single 20 mg dose of ibogaine in healthy volunteers. Journal of Clinical Pharmacology, 55(6), 680-687. doi: 10.1002/jcph.471

Journal - Research Article

Shadli, S. M., Glue, P., McIntosh, J., & McNaughton, N. (2015). An improved human anxiety process biomarker: Characterization of frequency band, personality and pharmacology. Translational Psychiatry, 5, e699. doi: 10.1038/tp.2015.188

Journal - Research Article

Alvarez-Grandi, S., Leon de la Barra, S., Seifert, A., & Glue, P. (2014). Electroconvulsive therapy use in Otago, New Zealand: A 10-year retrospective audit of patient-level treatment data. Australian & New Zealand Journal of Psychiatry, 48(6), 548-553. doi: 10.1177/0004867413514119

Journal - Research Article

Baby, M., Glue, P., & Carlyle, D. (2014). 'Violence is not part of our job': A thematic analysis of psychiatric mental health nurses' experiences of patient assaults from a New Zealand perspective. Issues in Mental Health Nursing, 35(9), 647-655. doi: 10.3109/01612840.2014.892552

Journal - Research Article

Campbell, A., Ruffman, T., Murray, J. E., & Glue, P. (2014). Oxytocin improves emotion recognition for older males. Neurobiology of Aging, 35(10), 2246-2248. doi: 10.1016/j.neurobiolaging.2014.04.021

Journal - Research Article

Dyke, J., Hendry, K., Hill, J., Schultz, M., Mason, E., & Glue, P. (2014). Management of a cluster of foreign body ingestion incidents in patients with borderline personality disorder. Open Journal of Psychiatry, 4, 99-103. doi: 10.4236/ojpsych.2014.42014

Journal - Research Article

Gupta, S. K., Kantesaria, B., & Glue, P. (2014). Exploring the influence of renal dysfunction on the pharmaco-kinetics of ribavirin after oral and intravenous dosing. Drug Discoveries & Therapeutics, 8(2), 89-95. doi: 10.5582/ddt.8.89

Journal - Research Article

Lai, R., Katalinic, N., Glue, P., Somogyi, A. A., Mitchell, P. B., Leyden, J., … Loo, C. K. (2014). Pilot dose–response trial of i.v. ketamine in treatment-resistant depression. World Journal of Psychiatry, 15(7), 579-584. doi: 10.3109/15622975.2014.922697

Journal - Research Article

Lenagh-Glue, J., Glue, P., & Dawson, J. (2014). When the mandatory second opinion fails to approve compulsory treatment. Australasian Psychiatry, 22(4), 337-340. doi: 10.1177/1039856214537879

Journal - Research Article

Shelker, W., Poole, P., Bagg, W., Wood, I., & Glue, P. (2014). Postgraduation retention of medical students from Otago and Auckland medical programmes. New Zealand Medical Journal, 127(1388). Retrieved from http://www.nzma.org.nz/journal

Journal - Research Article

Shelker, W., Zaharic, T., Sijnja, B., & Glue, P. (2014). Influence of rural background and rural medical training on postgraduate medical training and location in New Zealand. New Zealand Medical Journal, 127(1403). Retrieved from http://www.nzma.org.nz/journal

Journal - Research Article

Chai, Y. K., Wheeler, Z., Herbison, P., Gale, C., & Glue, P. (2013). Factors associated with hospitalization of adult psychiatric patients: Cluster analysis. Australasian Psychiatry, 21(2), 141-146. doi: 10.1177/1039856213475682

Journal - Research Article

Glue, P., Al-Shaqsi, S., Hancock, D., Gale, C., Strong, B., & Schep, L. (2013). Hospitalisation associated with use of the synthetic cannabinoid K2. New Zealand Medical Journal, 126(1377). Retrieved from http://www.nzma.org.nz/journal

Journal - Research Article

Gupta, S. K., Kantesaria, B., & Glue, P. (2013). Pharmacokinetics and safety of single-dose ribavirin in patients with chronic renal impairment. Drug Discoveries & Therapeutics, 7(4), 158-163. doi: 10.5582/ddt.2013.v7.4.158

Journal - Research Article

Henry, M. E., Bolo, N. R., Zuo, C. S., Villafuerte, R. A., Cayetano, K., Glue, P., … Renshaw, P. F. (2013). Quantification of brain voriconazole levels in healthy adults using fluorine magnetic resonance spectroscopy. Antimicrobial Agents & Chemotherapy, 57(11), 5271-5276. doi: 10.1128/AAC.00394-13

Journal - Research Article

Katalinic, N., Lai, R., Somogyi, A., Mitchell, P. B., Glue, P., & Loo, C. K. (2013). Ketamine as a new treatment for depression: A review of its efficacy and adverse effects. Australian & New Zealand Journal of Psychiatry, 47(8), 710-727. doi: 10.1177/0004867413486842

Journal - Research Article

McNaughton, N., Swart, C., Neo, P., Bates, V., & Glue, P. (2013). Anti-anxiety drugs reduce conflict-specific “theta”: A possible human anxiety-specific biomarker. Journal of Affective Disorders, 148(1), 104-111. doi: 10.1016/j.jad.2012.11.057

Journal - Research Article

Patterson, T., Rapsey, C. M., & Glue, P. (2013). Systematic review of cognitive development across childhood in Down syndrome: Implications for treatment interventions. Journal of Intellectual Disability Research, 57(4), 306-318. doi: 10.1111/j.1365-2788.2012.01536.x

Journal - Research Article

Shelker, W., Herbison, P., Belton, A., & Glue, P. (2013). Factors related to postgraduate retention of medical graduates in New Zealand. New Zealand Medical Journal, 126(1371). Retrieved from http://www.nzma.org.nz/journal

Journal - Research Article

Canton, J., Scott, K., & Glue, P. (2012). Optimal treatment of social phobia: Systematic review and meta-analysis. Neuropsychiatric Disease & Treatment, 8, 203-215. doi: 10.2147/ndt.s23317

Journal - Research Article

Glue, P., Gale, C., Menkes, D. B., & Hung, N. (2012). Evaluation of bioequivalence between clozapine suspension and tablet formulations : A multiple-dose, fed and fasted Study. Clinical Drug Investigation, 32(11), 723-727. doi: 10.1007/s40261-012-0004-6

Journal - Research Article

Grott Zanicotti, C., Perez, D., & Glue, P. (2012). Mood and pain responses to repeat dose intramuscular ketamine in a depressed patient with advanced cancer. Journal of Palliative Medicine, 15(4), 400-403. doi: 10.1089/jpm.2011.0314

Journal - Research Article

Gupta, S. K., Kantesaria, B., & Glue, P. (2012). Pharmacokinetics, safety, and tolerability of ribavirin in hemodialysis-dependent patients. European Journal of Clinical Pharmacology, 68(4), 415-418. doi: 10.1007/s00228-011-1137-x

Journal - Research Article

Brier, M. E., Gaylor, S. K., McGovren, P., Glue, P., Fang, A., & Aronoff, G. R. (2011). Pharmacokinetics of dexrazoxane in subjects with impaired kidney function. Journal of Clinical Pharmacology, 51(5), 731-738. doi: 10.1177/0091270010369675

Journal - Research Article

Gandelman, K., Glue, P., Laskey, R., Jones, J., LaBadie, R., & Ose, L. (2011). An eight-week trial investigating the efficacy and tolerability of atorvastatin for children and adolescents with heterozygous familial hypercholesterolemia. Pediatric Cardiology, 32(4), 433-441. doi: 10.1007/s00246-011-9885-z

Journal - Research Article

Gandelman, K., Zhu, T., Fahmi, O. A., Glue, P., Lian, K., Obach, S., & Damle, B. (2011). Unexpected effect of rifampin on the pharmacokinetics of linezolid: In silico and in vitro approaches to explain its mechanism. Journal of Clinical Pharmacology, 51(2), 229-236. doi: 10.1177/0091270010366445

Journal - Research Article

Karayal, O. N., Glue, P., Bachinsky, M., Stewart, M., Chappell, P., Kolluri, S., & Cavus, I. (2011). Switching from quetiapine to ziprasidone: A sixteen-week, open-label, multicenter study evaluating the effectiveness and safety of ziprasidone in outpatient subjects with schizophrenia or schizoaffective disorder. Journal of Psychiatric Practice, 17(2), 100-109. doi: 10.1097/01.pra.0000396061.05269.c8

Journal - Research Article

Malhotra, B., Darsey, E., Crownover, P., Fang, J., & Glue, P. (2011). Comparison of pharmacokinetic variability of fesoterodine vs. tolterodine extended release in cytochrome P450 2D6 extensive and poor metabolizers. British Journal of Clinical Pharmacology, 72(2), 226-234. doi: 10.1111/j.1365-2125.2011.03948.x

Journal - Research Article

Malhotra, B., Darsey, E., Crownover, P., Fang, J., & Glue, P. (2011). Comparison of pharmcokinetic variability of fesoterodine vs. tolterodine extended release in cytochrome P450 2D6 extensive and poor metabolizers. British Journal of Pharmacology, 72(2), 226-234. doi: 10.1111/j.1365-2125.2011.03948.x

Journal - Research Article

Shelker, W., Belton, A., & Glue, P. (2011). Academic performance and career choices of older medical students at the University of Otago. New Zealand Medical Journal, 124(1346). Retrieved from http://journal.nzma.org.nz/journal/124-1346/4965/content.pdf

Journal - Research Article

Tarr, G. P., Glue, P., & Herbison, P. (2011). Comparative efficacy and acceptability of mood stabilizer and second generation antipsychotic monotherapy for acute mania: A systematic review and meta-analysis. Journal of Affective Disorders, 134(1-3), 14-19. doi: 10.1016/j.jad.2010.11.009

Journal - Research Article

Tarr, G. P., Herbison, G. P., Leon de la Barra, S., & Glue, P. (2011). Study design and patient characteristics and outcome in acute mania clinical trials. Bipolar Disorders, 13(2), 125-132. doi: 10.1111/j.1399-5618.2011.00904.x

Journal - Research Article

Alemayehu, D., Andrews, E. N., Glue, P., & Knirsch, C. A. (2010). Considerations for the design and conduct of a pharmacovigilance study involving mass drug administration in a resource-constrained setting. PLoS Neglected Tropical Diseases, 4(1), e564. doi: 10.1371/journal.pntd.0000564

Journal - Research Article

Andrews, E., Glue, P., Fang, J., Crownover, P., Tressler, R., & Damle, B. (2010). Assessment of the pharmacokinetics of co-administered maraviroc and raltegravir. British Journal of Clinical Pharmacology, 69(1), 51-57. doi: 10.1111/j.1365-2125.2009.03546.x

Journal - Research Article

Glue, P., Donovan, M. R., Kolluri, S., & Emir, B. (2010). Meta-analysis of relapse prevention antidepressant trials in depressive disorders. Australian & New Zealand Journal of Psychiatry, 44(8), 697-705. doi: 10.3109/00048671003705441

Journal - Research Article

Glue, P., Loan, A., & Gale, C. (2010). New prospects for the drug treatment of generalized anxiety disorder: A systematic review. Current Drug Therapy, 5(2), 86-94.

Journal - Research Article

Malhotra, B. K., Crownover, P. H., LaBadie, R., Glue, P., & MacDiarmid, S. A. (2010). The pharmacokinetic profile of fesoterodine 8 mg with daytime or nighttime dosing. European Journal of Clinical Pharmacology, 66(2), 171-176. doi: 10.1007/s00228-009-0748-y

Journal - Research Article

Simpson, D. M., Schifitto, G., Clifford, D. B., Murphy, T. K., Durso-De Cruz, E., Glue, P., … On behalf of the 1066 HIV Neuropathy Study Group. (2010). Pregabalin for painful HIV neuropathy: A randomized, double-blind, placebo-controlled trial. Neurology, 74(5), 413-420. doi: 10.1212/WNL.0b013e3181ccc6ef

Journal - Research Article

Sweeney, K. R., Gastonguay, M. R., Benincosa, L., Cronenberger, C. L., Glue, P., & Malhotra, B. K. (2010). Exposure-response modeling and clinical trial simulation of the effect of tolterodine on QT intervals in healthy volunteers. Drug Discoveries & Therapeutics, 4(1), 44-53.

Journal - Research Article

Citrome, L., Yang, R., Glue, P., & Karayal, O. N. (2009). Effect of ziprasidone dose on all-cause discontinuation rates in acute schizophrenia and schizoaffective disorder: A post-hoc analysis of 4 fixed-dose randomized clinical trials. Schizophrenia Research, 111(1-3), 39-45.

Journal - Research Article

Damle, B. D., Uderman, H., Biswas, P., Crownover, P., Lin, C., & Glue, P. (2009). Influence of CYP2C19 polymorphism on the pharmacokinetics of nelfinavir and its active metabolite. British Journal of Clinical Pharmacology, 68(5), 682-689. doi: 10.1111/j.1365-2125.2009.03499.x

Journal - Research Article

Damle, B., Fosser, C., Ito, K., Tran, A., Clax, P., Uderman, H., & Glue, P. (2009). Effects of standard and supratherapeutic doses of nelfinavir on cardiac repolarization: A thorough QT study. Journal of Clinical Pharmacology, 49(3), 291-300. doi: 10.1177/0091270008329551

Journal - Research Article

Gandelman, K., Alderman, J. A., Glue, P., Lombardo, I., LaBadie, R. R., Versavel, M., & Preskorn, S. H. (2009). The impact of calories and fat content of meals on oral ziprasidone absorption: A randomized, open-label, crossover trial. Journal of Clinical Psychiatry, 70(1), 58-62.

Journal - Research Article

Glue, P., & Patterson, T. (2009). Can drug treatments enhance learning in subjects with intellectual disability? Australian & New Zealand Journal of Psychiatry, 43(10), 899-904. doi: 10.1080/00048670903179178

Journal - Research Article

Lee, S., Malhotra, B., Creanga, D., Carlsson, M., & Glue, P. (2009). A meta-analysis of the placebo response in antimuscarinic drug trials for overactive bladder. BMC Medical Research Methodology, 9, 55. doi: 10.1186/1471-2288-9-55

Journal - Research Article

Andrews, E., Damle, B. D., Fang, A., Forster, G., Crownover, P., LaBadie, R., & Glue, P. (2008). Pharmacokinetics and tolerability of voriconazole and a combination oral contraceptive co-administered in healthy female subjects. British Journal of Clinical Pharmacology, 65(4), 531-539. doi: 10.1111/j.1365-2125.2007.03084.x

Journal - Research Article

Damle, B., LaBadie, R., Crownover, P., & Glue, P. (2008). Pharmacokinetic interactions of efavirenz and voriconazole in healthy volunteers. British Journal of Clinical Pharmacology, 65(4), 523-530. doi: 10.1111/j.1365-2125.2007.03085.x

Journal - Research Article

El-Tahtawy, A., Glue, P., Andrews, E. N., Mardekian, J., Amsden, G. W., & Knirsch, C. A. (2008). The effect of azithromycin on ivermectin pharmacokinetics: A population pharmacokinetic model analysis. PLoS Neglected Tropical Diseases, 2(5), e236. Retrieved from http://www.plosntds.org/article/info%3Adoi%2F10.1371%2Fjournal.pntd.0000236

Journal - Research Article

Fang, A. F., Damle, B. D., LaBadie, R. R., Crownover, P. H., Hewlett, Jr, D., & Glue, P. W. (2008). Significant decrease in nelfinavir systemic exposure after omeprazole coadministration in healthy subjects. Pharmacotherapy, 28(1), 42-50.

Journal - Research Article

Amsden, G. W., Gregory, T. B., Michalak, C. A., Glue, P., & Knirsch, C. A. (2007). Pharmacokinetics of azithromycin and the combination of ivermectin and albendazole when administered alone and concurrently in healthy volunteers. American Journal of Tropical Medicine & Hygiene, 76(6), 1153-1157.

Journal - Research Article

Malhotra, B. K., Glue, P., Sweeney, K., Anziano, R., Mancuso, J., & Wicker, P. (2007). Thorough QT study with recommended and supratherapeutic doses of tolterodine. Clinical Pharmacology & Therapeutics, 81(3), 377-385. doi: 10.1038/sj.clpt.6100089

Journal - Research Article

Miceli, J. J., Glue, P., Alderman, J., & Wilner, K. (2007). The effect of food on the absorption of oral ziprasidone. Psychopharmacology Bulletin, 40(3), 58-68.

Journal - Research Article

Parker, J. D., Bart, B. A., Webb, D. J., Koren, M. J., Siegel, R. L., Wang, H., … Glue, P. (2007). Safety of intravenous nitroglycerin after administration of sildenafil citrate to men with coronary artery disease: A double-blind, placebo-controlled, randomized, crossover trial. Critical Care Medicine, 35(8), 1863-1868. doi: 10.1097/01.CCM.0000269371.70738.30

Journal - Research Article

Chung, M., Calcagni, A., Glue, P., & Bramson, C. (2006). Bioavailability of amlodipine besylate/atorvastatin calcium combination tablet. Journal of Clinical Pharmacology, 46(9), 1030-1037. doi: 10.1177/0091270006291031

Journal - Research Article

More publications...