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Contact Details

Phone
64 3 364 1222
Email
john.pearson@otago.ac.nz
Position
Research Associate Professor; Biostatistician; Director, UOC Biostatistics and Computational Biology Unit
Department
Dean's Department (Christchurch)
Qualifications
BSc MSc PhD
Research summary
Biostatistics

Research

  • Microarrays
  • Genetics
  • Bioinformatics
  • Statistical Computing
  • Survey Methods

Publications

Hock, B. D., Goddard, L., MacPherson, S. A., Strother, M., Gibbs, D., Pearson, J. F., & McKenzie, J. L. (2023). Levels and in vitro functional effects of circulating anti-hinge antibodies in melanoma patients receiving the immune checkpoint inhibitor pembrolizumab. PLoS ONE, 18(9), e0290793. doi: 10.1371/journal.pone.0290793

Sulit, A. K., Daigneault, M., Allen-Vercoe, E., Silander, O. K., Hock, B., McKenzie, J., Pearson, J., Frizelle, F. A., Schmeier, S., & Purcell, R. (2023). Bacterial lipopolysaccharide modulates immune response in the colorectal tumor microenvironment. npj Biofilms & Microbiomes, 9, 59. doi: 10.1038/s41522-023-00429-w

Sulit, A. K., Wilson, K., Pearson, J., Silander, O. K., Sampurno, S., Michael, M., … Frizelle, F., & Purcell, R. V. (2023). Human gene and microbial analyses in rectal cancer complete responses to radiotherapy. BJS Open, 7(3), zrad035. doi: 10.1093/bjsopen/zrad035

Leadbetter, R., MacAskill, M., Myall, D. J., Taylor, B. V., Joshi, P., NZMSPS group, including Pearson, J. F., Clarke, G., Abernethy, D. A., & Mason, D. F. (2023). Multiple sclerosis mortality in New Zealand: A nationwide prospective study. Journal of Neurology, Neurosurgery & Psychiatry. Advance online publication. doi: 10.1136/jnnp-2022-330582

Thompson, N., Gatenby, G., Waddell, O., Purcell, R., Keenan, J., Pearson, J. F., Frizelle, F., & Glyn, T. (2023). Early onset colorectal cancer in Canterbury, New Zealand. ANZ Journal of Surgery, 93, 2148-2154. doi: 10.1111/ans.18357

Amir, I., Thomson, B. J., Herrod, J., Souter, M. A., Mustard, J., Pearson, J. F., & Bird, P. (2023). The effect of universal newborn hearing screening on spoken language after cochlear implantation. Otology & Neurotology, 44(3), e133-e139. doi: 10.1097/MAO.0000000000003793

Journal - Research Article

Hock, B. D., Goddard, L., MacPherson, S. A., Strother, M., Gibbs, D., Pearson, J. F., & McKenzie, J. L. (2023). Levels and in vitro functional effects of circulating anti-hinge antibodies in melanoma patients receiving the immune checkpoint inhibitor pembrolizumab. PLoS ONE, 18(9), e0290793. doi: 10.1371/journal.pone.0290793

Journal - Research Article

Johnson, J. S., Cote, A. C., Dobbyn, A., Sloofman, L. G., Xu, J., Cotter, L., … Eating Disorders Working Group of the Psychiatric Genomics Consortium, including Boden, J. M., Pearson, J. F., … Jordan, J., Kennedy, M., … Huckins, L. M. (2023). Mapping anorexia nervosa genes to clinical phenotypes. Psychological Medicine, 53, 2619-2633. doi: 10.1017/s0033291721004554

Journal - Research Article

Leadbetter, R., MacAskill, M., Myall, D. J., Taylor, B. V., Joshi, P., NZMSPS group, including Pearson, J. F., Clarke, G., Abernethy, D. A., & Mason, D. F. (2023). Multiple sclerosis mortality in New Zealand: A nationwide prospective study. Journal of Neurology, Neurosurgery & Psychiatry. Advance online publication. doi: 10.1136/jnnp-2022-330582

Journal - Research Article

Lee, M. S., Thomas, A., Pearson, J. F., Purcell, R., Frizelle, F., & Glyn, T. (2023). Risk of colorectal cancer in patients with appendicitis over the age of 40 years. Colorectal Disease, 25, 624-630. doi: 10.1111/codi.16429

Journal - Research Article

Sulit, A. K., Daigneault, M., Allen-Vercoe, E., Silander, O. K., Hock, B., McKenzie, J., Pearson, J., Frizelle, F. A., Schmeier, S., & Purcell, R. (2023). Bacterial lipopolysaccharide modulates immune response in the colorectal tumor microenvironment. npj Biofilms & Microbiomes, 9, 59. doi: 10.1038/s41522-023-00429-w

Journal - Research Article

Sulit, A. K., Wilson, K., Pearson, J., Silander, O. K., Sampurno, S., Michael, M., … Frizelle, F., & Purcell, R. V. (2023). Human gene and microbial analyses in rectal cancer complete responses to radiotherapy. BJS Open, 7(3), zrad035. doi: 10.1093/bjsopen/zrad035

Journal - Research Article

Thompson, N., Gatenby, G., Waddell, O., Purcell, R., Keenan, J., Pearson, J. F., Frizelle, F., & Glyn, T. (2023). Early onset colorectal cancer in Canterbury, New Zealand. ANZ Journal of Surgery, 93, 2148-2154. doi: 10.1111/ans.18357

Journal - Research Article

Aitchison, A., Pearson, J. F., Purcell, R. V., Frizelle, F. A., & Keenan, J. I. (2022). Detection of Fusobacterium nucleatum DNA in primary care patient stool samples does not predict progression of colorectal neoplasia. PLoS ONE, 17(6), e0269541. doi: 10.1371/journal.pone.0269541

Journal - Research Article

Hakkaart, C., Pearson, J. F., Marquart, L., Dennis, J., Wiggins, G. A. R., Barnes, D. R., Robinson, B. A., Mace, P. D., … Walker, L. C. (2022). Copy number variants as modifiers of breast cancer risk for BRCA1/BRCA2 pathogenic variant carriers. Communications Biology, 5, 1061. doi: 10.1038/s42003-022-03978-6

Journal - Research Article

Hitchman, L. M., Faatoese, A., Merriman, T. R., Miller, A. L., Liau, Y., Graham, O. E. E., Kee, P. S., Pearson, J. F., … Cameron, V. A., Kennedy, M. A., & Maggo, S. D. S. (2022). Allelic diversity of the pharmacogene CYP2D6 in New Zealand Māori and Pacific peoples. Frontiers in Genetics, 13, 1016416. doi: 10.3389/fgene.2022.1016416

Journal - Research Article

Noble, A. J., Pearson, J. F., Noble, A. D., Boden, J. M., Horwood, L. J., Kennedy, M. A., & Osborne, A. J. (2022). DNA methylation analysis using bisulphite-based amplicon sequencing of individuals exposed to maternal tobacco use during pregnancy, and offspring conduct problems in childhood and adolescence. Reproduction, Fertility & Development, 34(7), 540-548. doi: 10.1071/rd21108

Journal - Research Article

Ward, Z., Schmeier, S., Pearson, J., Cameron, V. A., Frampton, C. M., Troughton, R. W., … Richards, A. M., & Pilbrow, A. P. (2022). Identifying candidate circulating RNA markers for coronary artery disease by deep RNA-sequencing in human plasma. Cell, 11, 3191. doi: 10.3390/cells11203191

Journal - Research Article

Gatenby, G., Glyn, T., Pearson, J., Gearry, R., & Eglinton, T. (2021). The long-term incidence of dysplasia and colorectal cancer in a Crohn’s colitis population-based cohort. Colorectal Disease, 23, 2399-2406. doi: 10.1111/codi.15756

Journal - Research Article

Ip, H. F., van der Laan, C. M., Krapohl, E. M. L., Brikell, I., Sánchez-Mora, C., Nolte, I. M., … Miller, A., … Boden, J., Pearson, J., Horwood, L. J., Kennedy, M., Poulton, R., … Boomsma, D. I. (2021). Genetic association study of childhood aggression across raters, instruments, and age. Translational Psychiatry, 11, 413. doi: 10.1038/s41398-021-01480-x

Journal - Research Article

Lattimore, V., Parsons, M. T., Spurdle, A. B., Pearson, J., Lehnert, K., Sullivan, J., … Morrin, H., Robinson, B., & Walker, L. (2021). Under-ascertainment of breast cancer susceptibility gene carriers in a cohort of New Zealand female breast cancer patients. Breast Cancer Research & Treatment, 185, 583-590. doi: 10.1007/s10549-020-05986-8

Journal - Research Article

Mears, E. R., Handley, R. R., Grant, M. J., Reid, S. J., Day, B. J., Rudiger, S. R., … Pearson, J. F., … Snell, R. G. (2021). A multi-omic Huntington's disease transgenic sheep-model database for investigating disease pathogenesis. Journal of Huntington's Disease, 10, 423-434. doi: 10.3233/jhd-210482

Journal - Research Article

Morley-Bunker, A. E., Wiggins, G. A. R., Currie, M. J., Morrin, H. R., Whitehead, M. R., Eglinton, T., Pearson, J., & Walker, L. C. (2021). RNAscope compatibility with image analysis platforms for the quantification of tissue-based colorectal cancer biomarkers in archival formalin-fixed paraffin-embedded tissue. Acta Histochemica, 123, 151765. doi: 10.1016/j.acthis.2021.151765

Journal - Research Article

Munn-Chernoff, M. A., Johnson, E. C., Chou, Y.-L., Coleman, J. R. I., Thornton, L. M., Walters, R. K., … Boden, J. M., … Horwood, L. J., … Pearson, J. F., … Jordan, J., Kennedy, M. A., … Agrawal, A. (2021). Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies. Addiction Biology, 26, e12880. doi: 10.1111/adb.12880

Journal - Research Article

Nabais, M. F., Laws, S. M., Lin, T., Vallerga, C. L., Armstrong, N. J., Blair, I. P., … Anderson, T. J., … Kennedy, M., … Pearson, J., Pitcher, T. L., … McRae, A. F. (2021). Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders. Genome Biology, 22(1), 90. doi: 10.1186/s13059-021-02275-5

Journal - Research Article

Noble, A. J., Pearson, J. F., Boden, J. M., Horwood, L. J., Gemmell, N. J., Kennedy, M. A., & Osborne, A. J. (2021). A validation of Illumina EPIC array system with bisulfite-based amplicon sequencing. PeerJ, 9, e10762. doi: 10.7717/peerj.10762

Journal - Research Article

Sabel, C. E., Pearson, J. F., Mason, D. F., Willoughby, E., Abernethy, D., & Taylor, B. V. (2021). The latitude gradient for multiple sclerosis prevalence is established in the early lifecourse. Brain, 144, 2038-2046. doi: 10.1093/brain/awab104

Journal - Research Article

Sinha, P., Cree, S. L., Miller, A. L., Pearson, J. F., & Kennedy, M. A. (2021). Transcriptional analysis of sodium valproate in a serotonergic cell line reveals gene regulation through both HDAC inhibition-dependent and independent mechanisms. Pharmacogenomics Journal, 21, 359-375. doi: 10.1038/s41397-021-00215-x

Journal - Research Article

Ward, Z., Schmeier, S., Saddic, L., Sigurdsson, M. I., Cameron, V. A., Pearson, J., Miller, A., Morley-Bunker, A., … Pilbrow, A. P. (2021). Novel and annotated long noncoding RNAs associated with ischemia in the human heart. International Journal of Molecular Sciences, 22, 11324. doi: 10.3390/ijms222111324

Journal - Research Article

Wiggins, G. A. R., Black, M. A., Dunbier, A., Merriman, T. R., Pearson, J. F., & Walker, L. C. (2021). Variable expression quantitative trait loci analysis of breast cancer risk variants. Scientific Reports, 11(1), 7192. doi: 10.1038/s41598-021-86690-5

Journal - Research Article

Wiggins, G. A. R., Black, M. A., Dunbier, A., Morley-Bunker, A. E., kConFab Investigators, Pearson, J. F., & Walker, L. C. (2021). Increased gene expression variability in BRCA1-associated and basal-like breast tumours. Breast Cancer Research & Treatment, 189, 363-375. doi: 10.1007/s10549-021-06328-y

Journal - Research Article

Bryois, J., Skene, N. G., Folmann Hansen, T., Kogelman, L. J. A., Watson, H. J., Liu, Z., … Eating Disorders Working Group of the Psychiatric Genomics Consortium, including Boden, J., … Jordan, J., … Kennedy, M., … Pearson, J., … Sullivan, P. F. (2020). Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson’s disease. Nature Genetics, 52, 482-493. doi: 10.1038/s41588-020-0610-9

Journal - Research Article

Chittleborough, T. J., Gutlic, I., Pearson, J. F., Watson, A., Bhatti, L. A., Buchwald, P., … Wakeman, C., Eglinton, T., & Frizelle, F. (2020). Increasing incidence of young-onset colorectal carcinoma: A three-country population analysis. Diseases of the Colon & Rectum, 63, 903-910. doi: 10.1097/DCR.0000000000001631

Journal - Research Article

Dickerhof, N., Huang, J., Min, E., Michaëlsson, E., Lindstedt, E.-L., Pearson, J. F., Kettle, A. J., & Day, B. J. (2020). Myeloperoxidase inhibition decreases morbidity and oxidative stress in mice with cystic fibrosis-like lung inflammation. Free Radical Biology & Medicine, 152, 91-99. doi: 10.1016/j.freeradbiomed.2020.03.001

Journal - Research Article

Johnson, E. C., Demontis, D., Thorgeirsson, T. E., Walters, R. K., Polimanti, R., Hatoum, A. S., … Boden, J., … Pearson, J. F., … Horwood, J., … Kennedy, M. A., … Agrawal, A. (2020). A large-scale genome-wide association study meta-analysis of cannabis use disorder. Lancet Psychiatry, 7, 1032-1045. doi: 10.1016/S2215-0366(20)30339-4

Journal - Research Article

O'Grady, M., Clarke, L., Turner, G., Doogue, M., Purcell, R., Pearson, J., & Frizelle, F. (2020). Statin use and risk of acute diverticulitis: A population-based case-control study. Medicine, 99(20), e20264. doi: 10.1097/md.0000000000020264

Journal - Research Article

Osborne, A. J., Pearson, J. F., Noble, A. J., Gemmell, N. J., Horwood, L. J., Boden, J. M., … Kennedy, M. A. (2020). Genome-wide DNA methylation analysis of heavy cannabis exposure in a New Zealand longitudinal cohort. Translational Psychiatry, 10, 114. doi: 10.1038/s41398-020-0800-3

Journal - Research Article

Pearson, A. G., Zawari, M., Pearson, J. F., & Hampton, M. B. (2020). Quantifying mitochondrial respiration in human lymphocytes and monocytes challenged with hydrogen peroxide. Free Radical Research, 54(4), 271-279. doi: 10.1080/10715762.2020.1753722

Journal - Research Article

Porter, J. A., MacKenzie, K. E., Darlow, B. A., Pearson, J. F., & Day, A. S. (2020). A questionnaire-based assessment of gastrointestinal symptoms in children with type 1 diabetes mellitus. Translational Pediatrics, 9(6), 743-749. doi: 10.21037/tp-20-139

Journal - Research Article

Richardson, A. K., Walker, L. C., Cox, B., Rollag, H., Robinson, B. A., Morrin, H., Pearson, J. F., … Currie, M. J. (2020). Breast cancer and cytomegalovirus. Clinical & Translational Oncology, 22, 585-602. doi: 10.1007/s12094-019-02164-1

Journal - Research Article

Slow, S., Pearson, J. F., Florkowski, C. M., Elder, P. A., Lewis, J. G., Kennedy, M. A., & Murdoch, D. R. (2020). Effect of genetic factors on the response to vitamin D3 supplementation in the VIDARIS randomised controlled trial. Nutrition, 75-76, 110761. doi: 10.1016/j.nut.2020.110761

Journal - Research Article

Taylor, W. S., Pearson, J., Miller, A., Schmeier, S., Frizelle, F. A., & Purcell, R. V. (2020). MinION sequencing of colorectal cancer tumour microbiomes: A comparison with amplicon-based and RNA-sequencing. PLoS ONE, 15(5), e0233170. doi: 10.1371/journal.pone.0233170

Journal - Research Article

Tranter-Entwistle, I., Mullaney, T. G., Noah, K., Pearson, J., Falvey, J., Gearry, R., & Eglinton, T. (2020). Long-term incidence of dysplasia and colorectal cancer in an ulcerative colitis population-based cohort. ANZ Journal of Surgery, 90, 821-825. doi: 10.1111/ans.15686

Journal - Research Article

White, R., Nonis, M., Pearson, J. F., Burgess, E., Morrin, H. R., Pullar, J. M., Spencer, E., Vissers, M. C. M., Robinson, B. A., & Dachs, G. U. (2020). Low vitamin C status in patients with cancer is associated with patient and tumor characteristics. Nutrients, 12(8), 2338. doi: 10.3390/nu12082338

Journal - Research Article

Balasubramanian, D., Pearson, J. F., & Kennedy, M. A. (2019). Gene expression effects of lithium and valproic acid in a serotonergic cell line. Physiological Genomics, 51, 43-50. doi: 10.1152/physiolgenomics.00069.2018

Journal - Research Article

Hock, B. D., Mulholland, K. S., Ganly, P., McKenzie, J. L., Pearson, J. F., & MacPherson, S. A. (2019). Impact of increased access to novel agents on the survival of multiple myeloma patients treated at a single New Zealand centre. Internal Medicine Journal, 49, 598-606. doi: 10.1111/imj.14155

Journal - Research Article

Keenan, J., Aitchison, A., Leaman, J., Pearson, J., & Frizelle, F. (2019). Faecal biomarkers do not always identify pre-cancerous lesions in patients who present in primary care with bowel symptoms. New Zealand Medical Journal, 132(1501), 48-56. Retrieved from https://www.nzma.org.nz/journal

Journal - Research Article

Lattimore, V. L., Pearson, J. F., Morley-Bunker, A. E., kConFab Investigators, Spurdle, A. B., Robinson, B. A., Currie, M. J., & Walker, L. C. (2019). Quantifying BRCA1 and BRCA2 mRNA isoform expression levels in single cells. International Journal of Molecular Sciences, 20(3), 693. doi: 10.3390/ijms20030693

Journal - Research Article

Liau, Y., Cree, S. L., Maggo, S., Miller, A. L., Pearson, J. F., Gladding, P. A., & Kennedy, M. A. (2019). A multiplex pharmacogenetics assay using the MinION nanopore sequencing device. Pharmacogenetics & Genomics, 29(9), 207-215. doi: 10.1097/fpc.0000000000000385

Journal - Research Article

Liau, Y., Maggo, S., Miller, A. L., Pearson, J. F., Kennedy, M. A., & Cree, S. L. (2019). Nanopore sequencing of the pharmacogene CYP2D6 allows simultaneous haplotyping and detection of duplications. Pharmacogenomics, 20(14), 1033-1047. doi: 10.2217/pgs-2019-0080

Journal - Research Article

Lopez-Perolio, I., Leman, R., Behar, R., Lattimore, V., Pearson, J. F., Castéra, L., … Walker, L. C., … de la Hoya, M. (2019). Alternative splicing and ACMG-AMP-2015-based classification of PALB2 genetic variants: An ENIGMA report. Journal of Medical Genetics, 56, 453-460. doi: 10.1136/jmedgenet-2018-105834

Journal - Research Article

Morley-Bunker, A., Pearson, J., Currie, M. J., Morrin, H., Whitehead, M. R., Eglinton, T., & Walker, L. C. (2019). Assessment of intra-tumoural colorectal cancer prognostic biomarkers using RNA in situ hybridisation. Oncotarget, 10(14), 1425-1439. doi: 10.18632/oncotarget.26675

Journal - Research Article

Pettersson, E., Lichtenstein, P., Larsson, H., Song, J., Attention Deficit/Hyperactivity Disorder Working Group of the iPSYCH-Broad-PGC Consortium, Autism Spectrum Disorder Working Group of the iPSYCH-Broad-PGC Consortium, Bipolar Disorder Working Group of the PGC, Eating Disorder Working Group of the PGC, including Kennedy, M. A., Major Depressive Disorder Working Group of the PGC, Obsessive Compulsive Disorders and Tourette Syndrome Working Group of the PGC, Schizophrenia CLOZUK, Substance Use Disorder Working Group of the PGC, including Horwood, L. J., Pearson, J. F., … Polderman, T. J. C. (2019). Genetic influences on eight psychiatric disorders based on family data of 4 408 646 full and half-siblings, and genetic data of 333 748 cases and controls. Psychological Medicine, 49(7), 1166-1173. doi: 10.1017/S0033291718002039

Journal - Research Article

Prickett, T. C. R., Spittlehouse, J. K., Miller, A. L., Liau, Y., Kennedy, M. A., Cameron, V. A., Pearson, J. F., Boden, J. M., Troughton, R. W., & Espiner, E. A. (2019). Contrasting signals of cardiovascular health among natriuretic peptides in subjects without heart disease. Scientific Reports, 9, 12108. doi: 10.1038/s41598-019-48553-y

Journal - Research Article

Purcell, R. V., Schmeier, S., Lau, Y. C., Pearson, J. F., & Frizelle, F. A. (2019). Molecular subtyping improves prognostication of Stage 2 colorectal cancer. BMC Cancer, 19(1), 1155. doi: 10.1186/s12885-019-6327-4

Journal - Research Article

Reynolds, R. H., Botía, J., Nalls, M. A., International Parkinson's Disease Genomics Consortium (IPDGC), including System Genomics of Parkinson's Disease (SGPD), Anderson, T., … Kennedy, M., Pearson, J., … Ryten, M. (2019). Moving beyond neurons: The role of cell type-specific gene regulation in Parkinson's disease heritability. npj Parkinson's Disease, 5, 6. doi: 10.1038/s41531-019-0076-6

Journal - Research Article

Thompson, G., & Pearson, J. F. (2019). No attributable effects of PRP on greater trochanteric pain syndrome. New Zealand Medical Journal, 132(1507), 22-32. Retrieved from https://www.nzma.org.nz/journal

Journal - Research Article

Watson, H. J., Yilmaz, Z., Thornton, L. M., Hübel, C., Coleman, J. R. I., Gaspar, H. A., … Roberts, M., … Boden, J. M., … Horwood, L. J., … Pearson, J. F., … Jordan, J., Kennedy, M., … Bulik, C. M. (2019). Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa. Nature Genetics, 51, 1207-1214. doi: 10.1038/s41588-019-0439-2

Journal - Research Article

Zhang, Q., Vallerga, C. L., Walker, R. M., Lin, T., Henders, A. K., Montgomery, G. W., … Kennedy, M., Pitcher, T., Pearson, J., … Anderson, T., … Visscher, P. M. (2019). Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing. Genome Medicine, 11(1), 54. doi: 10.1186/s13073-019-0667-1

Journal - Research Article

Lacey, C. J., Doudney, K., Bridgman, P. G., George, P. M., Mulder, R. T., Zarifeh, J. J., Kimber, B., Cadzow, M. J., Black, M. A., Merriman, T. R., … Pearson, J. F., Cameron, V. A., & Kennedy, M. A. (2018). Copy number variants implicate cardiac function and development pathways in earthquake-induced stress cardiomyopathy. Scientific Reports, 8, 7548. doi: 10.1038/s41598-018-25827-5

Journal - Research Article

Lattimore, V. L., Pearson, J. F., Currie, M. J., Spurdle, A. B., kConFab Investigators, Robinson, B. A., & Walker, L. C. (2018). Investigation of experimental factors that underlie BRCA1/2 mRNA isoform expression variation: Recommendations for utilising targeted RNA sequencing to evaluate potential spliceogenic variants. Frontiers in Oncology, 8, 140. doi: 10.3389/fonc.2018.00140

Journal - Research Article

Newlands, S., Dickson, J., Pearson, J., Mansell, C., & Wilson, G. (2018). Neonatal conjunctivitis in the New Zealand Midland region. New Zealand Medical Journal, 131(1486), 9-17. Retrieved from https://www.nzma.org.nz/journal

Journal - Research Article

Pitcher, T. L., Myall, D. J., Pearson, J. F., Lacey, C. J., Dalrymple-Alford, J. C., Anderson, T. J., & MacAskill, M. R. (2018). Parkinson's disease across ethnicities: A nationwide study in New Zealand. Movement Disorders, 33(9), 1440-1448. doi: 10.1002/mds.27389

Journal - Research Article

Purcell, R. V., Kaakoush, N. O., Mitchell, H. M., Pearson, J. F., & Keenan, J. I. (2018). Gastrointestinal pathobionts in pediatric Crohn's disease patients. International Journal of Microbiology, 2018, 9203908. doi: 10.1155/2018/9203908

Journal - Research Article

Slow, S., Epton, M., Storer, M., Thiessen, R., Lim, S., Wong, J., Chin, P., Tovaranonte, P., Pearson, J., Chambers, S. T., Murdoch, D. R., and VIDCAPS Group, including Jardine, D., & Pithie, A. (2018). Effect of adjunctive single high-dose vitamin D3 on outcome of community-acquired pneumonia in hospitalised adults: The VIDCAPS randomised controlled trial. Scientific Reports, 8(1), 13829. doi: 10.1038/s41598-018-32162-2

Journal - Research Article

Stevens, A. J., Rucklidge, J. J., Darling, K. A., Eggleston, M. J. F., Pearson, J. F., & Kennedy, M. A. (2018). Methylomic changes in response to micronutrient supplementation and MTHFR genotype. Epigenomics, 10(9), 1201-1214. doi: 10.2217/epi-2018-0029

Journal - Research Article

Thornton, L. M., Munn-Chernoff, M. A., Baker, J. H., Juréus, A., Parker, R., Henders, A. K., … Horwood, L. J., Boden, J. M., Pearson, J. F., … Jordan, J., Kennedy, M. A., … Bulik, C. M. (2018). The Anorexia Nervosa Genetics Initiative (ANGI): Overview and methods. Contemporary Clinical Trials, 74, 61-69. doi: 10.1016/j.cct.2018.09.015

Journal - Research Article

Turner, R., Brennan, S. O., Ashby, L. V., Dickerhof, N., Hamzah, M. R., Pearson, J. F., Stamp, L. K., & Kettle, A. J. (2018). Conjugation of urate-derived electrophiles to proteins during normal metabolism and inflammation. Journal of Biological Chemistry, 293(51), 19886-19898. doi: 10.1074/jbc.RA118.005237

Journal - Research Article

Walters, R. K., Polimanti, R., Johnson, E. C., McClintick, J. N., Adams, M. J., Adkins, A. E., … Kennedy, M. A., … Pearson, J. F., … Agrawal, A. (2018). Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders. Nature Neuroscience, 21(12), 1656-1669. doi: 10.1038/s41593-018-0275-1

Journal - Research Article

Appleby, S., Pearson, J. F., Aitchison, A., Spittlehouse, J. K., Joyce, P. R., & Kennedy, M. A. (2017). Mean telomere length is not associated with current health status in a 50-year-old population sample. American Journal of Human Biology, 29(1), e22906. doi: 10.1002/ajhb.22906

Journal - Research Article

Dickerhof, N., Pearson, J. F., Hoskin, T. S., Berry, L. J., Turner, R., Sly, P. D., Kettle, A. J., on behalf of AREST CF. (2017). Oxidative stress in early cystic fibrosis lung disease is exacerbated by airway glutathione deficiency. Free Radical Biology & Medicine, 113, 236-243. doi: 10.1016/j.freeradbiomed.2017.09.028

Journal - Research Article

Gandhi, J., Davidson, C., Hall, C., Pearson, J., Eglinton, T., Wakeman, C., & Frizelle, F. (2017). Population-based study demonstrating an increase in colorectal cancer in young patients. British Journal of Surgery, 104(8), 1063-1068. doi: 10.1002/bjs.10518

Journal - Research Article

Grant, E., Gearry, R. B., Wilson, R., Pearson, J., & Skidmore, P. M. L. (2017). Home availability of fruit and vegetables and obesogenic foods as an indicator of nutrient intake in 50 year olds from Canterbury, New Zealand. Asia Pacific Journal of Clinical Nutrition, 26(3), 524-530. doi: 10.6133/apjcn.042016.11

Journal - Research Article

Maggo, S. D. S., Chua, E. W., Chin, P., Cree, S., Pearson, J., Doogue, M., & Kennedy, M. A. (2017). A New Zealand platform to enable genetic investigation of adverse drug reactions. New Zealand Medical Journal, 130(1466), 62-69. Retrieved from http://www.nzma.org.nz/journal

Journal - Research Article

Myall, D. J., Pitcher, T. L., Pearson, J. F., Dalrymple-Alford, J. C., Anderson, T. J., & MacAskill, M. R. (2017). Parkinson's in the oldest old: Impact on estimates of future disease burden. Parkinsonism & Related Disorders, 42, 78-84. doi: 10.1016/j.parkreldis.2017.06.018

Journal - Research Article

Pearson, J. F., Alla, S., Clarke, G., Mason, D. F., Anderson, T., Richardson, A., Miller, D. H., … Abernethy, D. A., … Taylor, B. V. (2017). Multiple sclerosis impact on employment and income in New Zealand. Acta Neurologica Scandinavica, 136(3), 223-232. doi: 10.1111/ane.12714

Journal - Research Article

Pearson, J. F., Pullar, J. M., Wilson, R., Spittlehouse, J. K., Vissers, M. C. M., Skidmore, P. M. L., Willis, J., Cameron, V. A., & Carr, A. C. (2017). Vitamin C status correlates with markers of metabolic and cognitive health in 50-year-olds: Findings of the CHALICE Cohort Study. Nutrients, 9(8), 831. doi: 10.3390/nu9080831

Journal - Research Article

Purcell, R. V., Pearson, J., Aitchison, A., Dixon, L., Frizelle, F. A., & Keenan, J. I. (2017). Colonization with enterotoxigenic Bacteroides fragilis is associated with early-stage colorectal neoplasia. PLoS ONE, 12(2), e0171602. doi: 10.1371/journal.pone.0171602

Journal - Research Article

Walker, L. C., Marquart, L., Pearson, J. F., Wiggins, G. A. R., O'Mara, T. A., Parsons, M. T., … Spurdle, A. B. (2017). Evaluation of copy-number variants as modifiers of breast and ovarian cancer risk for BRCA1 pathogenic variant carriers. European Journal of Human Genetics, 25, 432-438. doi: 10.1038/ejhg.2016.203

Journal - Research Article

Walker, L. C., Pearson, J. F., Wiggins, G. A. R., Giles, G. G., Hopper, J. L., & Southey, M. C. (2017). Increased genomic burden of germline copy number variants is associated with early onset breast cancer: Australian breast cancer family registry. Breast Cancer Research, 19, 30. doi: 10.1186/s13058-017-0825-6

Journal - Research Article

Alla, S., Pearson, J. F., Taylor, B. V., Miller, D. H., Clarke, G., Richardson, A., … Abernethy, D. A., … Mason, D. F. (2016). Disability profile of multiple sclerosis in New Zealand. Journal of Clinical Neuroscience, 28, 97-101. doi: 10.1016/j.jocn.2015.09.020

Journal - Research Article

Goh, T., Bird, P., Pearson, J., & Mustard, J. (2016). Educational, employment, and social participation of young adult graduates from the Southern Cochlear Implant Programme, New Zealand. Cochlear Implants International, 17(1), 31-51. doi: 10.1179/1754762815Y.0000000018

Journal - Research Article

Hock, B. D., McIntosh, N. D., McKenzie, J. L., Pearson, J. F., Simcock, J. W., & MacPherson, S. A. (2016). Incidence of cutaneous squamous cell carcinoma in a New Zealand population of chronic lymphocytic leukaemia patients. Internal Medicine Journal, 46(12), 1414-1421. doi: 10.1111/imj.13261

Journal - Research Article

Keenan, J. I., Aitchison, A., Purcell, R. V., Greenlees, R., Pearson, J. F., & Frizelle, F. A. (2016). Screening for enterotoxigenic Bacteroides fragilis in stool samples. Anaerobe, 40, 50-53. doi: 10.1016/j.anaerobe.2016.05.004

Journal - Research Article

Morley-Bunker, A., Walker, L. C., Currie, M. J., Pearson, J., & Eglinton, T. (2016). Translating colorectal cancer genetics into clinically useful biomarkers. Colorectal Disease, 18(8), 749-762. doi: 10.1111/codi.13334

Journal - Research Article

Purcell, R. V., Pearson, J., Frizelle, F. A., & Keenan, J. I. (2016). Comparison of standard, quantitative and digital PCR in the detection of enterotoxigenic Bacteroides fragilis. Scientific Reports, 6, 34554. doi: 10.1038/srep34554

Journal - Research Article

Seddon, A., Hock, B., Miller, A., Frei, L., Pearson, J., McKenzie, J., Simcock, J., & Currie, M. (2016). Cutaneous squamous cell carcinomas with markers of increased metastatic risk are associated with elevated numbers of neutrophils and/or granulocytic myeloid derived suppressor cells. Journal of Dermatological Science, 83(2), 124-130. doi: 10.1016/j.jdermsci.2016.04.013

Journal - Research Article

Spittlehouse, J. K., Vierck, E., Pearson, J. F., & Joyce, P. R. (2016). Personality, mental health and demographic correlates of hoarding behaviours in a midlife sample. PeerJ, 4, e2826. doi: 10.7717/peerj.2826

Journal - Research Article

Gerring, Z., Pearson, J. F., Morrin, H. R., Robinson, B. A., Harris, G. C., & Walker, L. C. (2015). Phosphohistone H3 outperforms Ki67 as a marker of outcome for breast cancer patients. Histopathology, 67(4), 538-547. doi: 10.1111/his.12678

Journal - Research Article

Jodczyk, S., Pearson, J. F., Aitchison, A., Miller, A. L., Hampton, M. B., & Kennedy, M. A. (2015). Telomere length measurement on the Roche LightCycler 480 platform. Genetic Testing & Molecular Biomarkers, 19(2), 63-68. doi: 10.1089/gtmb.2014.0208

Journal - Research Article

Moir-Meyer, G. L., Pearson, J. F., Lose, F., The Australian National Endometrial Cancer Study Group, Scott, R. J., McEvoy, M., … Walker, L. C. (2015). Rare germline copy number deletions of likely functional importance are implicated in endometrial cancer predisposition. Human Genetics, 134(3), 269-278. doi: 10.1007/s00439-014-1507-4

Journal - Research Article

Osborne, A. J., Pearson, J., Chilvers, B. L., Kennedy, M. A., & Gemmell, N. J. (2015). Examining the role of components of Slc11a1 (Nramp1) in the susceptibility of New Zealand sea lions (Phocarctos hookeri) to disease. PLoS ONE, 10(4), e0122703. doi: 10.1371/journal.pone.0122703

Journal - Research Article

Osborne, A. J., Pearson, J., Negro, S. S., Chilvers, B. L., Kennedy, M. A., & Gemmell, N. J. (2015). Heterozygote advantage at MHC DRB may influence response to infectious disease epizootics. Molecular Ecology, 24, 1419-1432. doi: 10.1111/mec.13128

Journal - Research Article

Richardson, A. K., Currie, M. J., Robinson, B. A., Morrin, H., Phung, Y., Pearson, J. F., … Walker, L. C. (2015). Cytomegalovirus and Epstein-Barr Virus in breast cancer. PLoS ONE, 10(2), e0118989. doi: 10.1371/journal.pone.0118989

Journal - Research Article

Walker, L. C., Wiggins, G. A. R., & Pearson, J. F. (2015). The role of constitutional copy number variants in breast cancer. Microarrays, 4(3), 407-423. doi: 10.3390/microarrays4030407

Journal - Research Article

Alla, S., Pearson, J., Debernard, L., Miller, D., & Mason, D. (2014). The increasing prevalence of multiple sclerosis in New Zealand. Neuroepidemiology, 42, 154-160. doi: 10.1159/000358174

Journal - Research Article

Jodczyk, S., Fergusson, D. M., Horwood, L. J., Pearson, J. F., & Kennedy, M. A. (2014). No association between mean telomere length and life stress observed in a 30 year birth cohort. PLoS ONE, 9(5), e97102. doi: 10.1371/journal.pone.0097102

Journal - Research Article

Kuiper, C., Dachs, G. U., Munn, D., Currie, M. J., Robinson, B. A., Pearson, J. F., & Vissers, M. C. M. (2014). Increased tumour ascorbate is associated with extended disease-free survival and decreased hypoxia-inducible factor-1 activation in human colorectal cancer. Frontiers in Oncology, 4, 10. doi: 10.3389/fonc.2014.00010

Journal - Research Article

Pearson, J. F., Alla, S., Clarke, G., Taylor, B. V., Miller, D. H., Richardson, A., & Mason, D. F. (2014). Multiple sclerosis in New Zealand Māori. Multiple Sclerosis Journal, 20(14), 1892-1895. doi: 10.1177/1352458514535130

Journal - Research Article

Spencer, R., Gearry, R., Pearson, J., & Skidmore, P. (2014). Relationship between fructose and lactose intakes and functional gastrointestinal symptoms in a sample of 50-year-old Cantabrians in New Zealand. New Zealand Medical Journal, 127(1406). Retrieved from http://www.nzma.org.nz/journal

Journal - Research Article

Spittlehouse, J. K., Joyce, P. R., Vierck, E., Schluter, P. J., & Pearson, J. F. (2014). Ongoing adverse mental health impact of the earthquake sequence in Christchurch, New Zealand. Australian & New Zealand Journal of Psychiatry, 48(8), 756-763. doi: 10.1177/0004867414527522

Journal - Research Article

Spittlehouse, J. K., Vierck, E., Pearson, J. F., & Joyce, P. R. (2014). Temperament and character as determinants of well-being. Comprehensive Psychiatry, 55(7), 1679-1687. doi: 10.1016/j.comppsych.2014.06.011

Journal - Research Article

Thorpe, A. M., Pearson, J. F., Schluter, P. J., Spittlehouse, J. K., & Joyce, P. R. (2014). Attitudes to aging in midlife are related to health conditions and mood. International Psychogeriatrics, 26(12), 2061-2071. doi: 10.1017/s1041610214001550

Journal - Research Article

Wall, C. L., Gearry, R. B., Pearson, J., Parnell, W., & Skidmore, P. M. L. (2014). Dietary intake in midlife and associations with standard of living, education and nutrition literacy. New Zealand Medical Journal, 127(1397). Retrieved from http://www.nzma.org.nz/journal

Journal - Research Article

Wilson, R., Gearry, R. B., Grant, E., Pearson, J., & Skidmore, P. M. L. (2014). Home food availability is associated with multiple socio-economic indicators in 50 year olds from Canterbury, New Zealand. Asia Pacific Journal of Clinical Nutrition, 23(4), 714-722. doi: 10.6133/apjcn.2014.23.4.04

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