Accessibility Skip to Global Navigation Skip to Local Navigation Skip to Content Skip to Search Skip to Site Map Menu

Delta-133p53 and Cancer Migration

A postgraduate research opportunity at the University of Otago.

Details

Academic background
Health Sciences
Host campus
Dunedin
Qualifications
Honours, Master’s
School
Otago Medical School
Supervisor
Dr Adele Woolley

Overview

p53 is a tumour suppressor gene that iencodes at least 12 isoforms. Several of the isoforms have been shown to moderate p53 activities [20-22] as well as having unique independent functions. Levels of the 133TP53 isoform are elevated in several cancers.

This project investigates the role of this isoform in cancer cell migration using a cultured human cancer cells model and quantifies alterations in cytoskeletal proteins in migration.

Contact

Dr Adele Woolley
Email   adele.woolley@otago.ac.nz