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Otago Medical School staff profiles

Professor Dee Mangin

PositionProfessor
DepartmentDepartment of General Practice (UOC)
QualificationsMBChB DPH (Otago)
Research summaryGeneral Practice

Research

Dee Mangin is a New Zealand family physician who is currently Professor and Director of the Primary Care Research Group at the Christchurch School of Medicine, University of Otago. Her interests are rational prescribing, and the influences of science, policy and commerce on the nature of care.

Expertise spans generation of clinical evidence using randomised controlled trials, the effects of pharmaceutical company promotion to consumers and physicians, effective medicine use in older age, innovative models of general practice care and effective incorporation of evidence into patient-centered practice.

Publications

Currie, O., Williman, J., Mangin, D., McKinnon-Gee, B., & Bridgford, P. (2019). Comparative risk of new-onset diabetes following commencement of antipsychotics in New Zealand: A population-based clustered multiple baseline time series design. BMJ Open, 9(2), e022984. doi: 10.1136/bmjopen-2018-022984

Ailabouni, N., Mangin, D., & Nishtala, P. S. (2019). DEFEAT-polypharmacy: Deprescribing anticholinergic and sedative medicines feasibility trial in residential aged care facilities. International Journal of Clinical Pharmacy. Advance online publication. doi: 10.1007/s11096-019-00784-9

Mangin, D., Lawson, J., Cuppage, J., Shaw, E., Ivanyi, K., Davis, A., & Risdon, C. (2018). Legacy drug-prescribing patterns in primary care. Annals of Family Medicine, 16(6), 515-520. doi: 10.1370/afm.2315

Stairmand, J., Gurney, J., Stanley, J., Millar, E., Davies, C., Semper, K., Dowell, A., Mangin, D., Lawrenson, R., & Sarfati, D. (2018). The impact of multimorbidity on people's lives: A cross-sectional survey. New Zealand Medical Journal, 131(1477), 78-90. Retrieved from https://www.nzma.org.nz/journal

Millar, E., Dowell, A., Lawrenson, R., Mangin, D., & Sarfati, D. (2018). Clinical guidelines: What happens when people have multiple conditions? New Zealand Medical Journal, 131(1472), 73-81. Retrieved from https://www.nzma.org.nz/journal

Edited Book - Research

Ingham, T., Jones, B., on behalf of the Pharmacovigilance Ethics Advisory Group, including Smith, B., Mangin, D., & Moore, A. (Eds.). (2012). Medicine safety for New Zealanders: Ethical issue regarding the use of routinely collected data from general practice for pharmacovigilance (Draft ed.). Wellington, New Zealand: University Of Otago, 46p.

Mintzes, B., Mangin, D., & Hayes, L. (Eds.). (2009). Understanding and responding to pharmaceutical promotion: A practical guide [Working draft for pilot field testing]. World Health Organization & Health Action International. Retrieved from http://www.haiweb.org/11062009/drug-promotion-manual-CAP-3-090610.pdf

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Chapter in Book - Research

Mangin, D. (2016). The contribution of primary care research to improving health services. In F. Goodyear-Smith & B. Mash (Eds.), International perspectives on primary care research. (pp. 67-72). Boca Raton, FL: CRC Press.

Healy, D., & Mangin, D. (2016). Does my bias look big in this? In F. Baylis & A. Ballantyne (Eds.), Clinical research involving pregnant women. (pp. 197-208). Springer. doi: 10.1007/978-3-319-26512-4_11

Mangin, D. (2015). A primary care perspective on prescribing for women. In M. Harrison-Woolrych (Ed.), Medicines for women. (pp. 403-432). Springer.

Mangin, D., & Heath, I. (2012). Polifarmácia [Polypharmacy]. In G. Gusso & J. M. C. Lopes (Eds.), Tratado de medicina de família e comunidadae [Textbook of family and community medicine]. (pp. 198-204). artmed.

Starfield, B., & Mangin, D. (2011). An international perspective on the basis of pay-for-performance. In S. Gillam & A. N. Siriwardena (Eds.), The quality and outcomes framework (QOF): Transforming general practice. (pp. 147-155). Abingdon, UK: Radcliffe.

Mangin, D. (2009). Promotion, professional practice and patient trust. In B. Mintzes, D. Mangin & L. Hayes (Eds.), Understanding and responding to pharmaceutical promotion: A practical guide [Working draft for pilot field testing]. (pp. 163-173). World Health Organization & Health Action International. Retrieved from http://www.haiweb.org/11062009/drug-promotion-manual-CAP-3-090610.pdf

Mintzes, B., Toop, L., & Mangin, D. (2009). Promotion to consumers: Responding to patient requests for advertised medicines. In B. Mintzes, D. Mangin & L. Hayes (Eds.), Understanding and responding to pharmaceutical promotion: A practical guide [Working draft for pilot field testing]. (pp. 81-104). World Health Organization & Health Action International. Retrieved from http://www.haiweb.org/11062009/drug-promotion-manual-CAP-3-090610.pdf

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Chapter in Book - Other

Toop, L., & Mangin, D. (2013). Marketing of pharmaceuticals. In P. Joyce, G. Nicholls, K. Thomas & T. Wilkinson (Eds.), The Christchurch experience: 40 years of research and teaching. (pp. 177-182). Christchurch, New Zealand: University of Otago.

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Journal - Research Article

Currie, O., Williman, J., Mangin, D., McKinnon-Gee, B., & Bridgford, P. (2019). Comparative risk of new-onset diabetes following commencement of antipsychotics in New Zealand: A population-based clustered multiple baseline time series design. BMJ Open, 9(2), e022984. doi: 10.1136/bmjopen-2018-022984

Ailabouni, N., Mangin, D., & Nishtala, P. S. (2019). DEFEAT-polypharmacy: Deprescribing anticholinergic and sedative medicines feasibility trial in residential aged care facilities. International Journal of Clinical Pharmacy. Advance online publication. doi: 10.1007/s11096-019-00784-9

Mangin, D., Lawson, J., Cuppage, J., Shaw, E., Ivanyi, K., Davis, A., & Risdon, C. (2018). Legacy drug-prescribing patterns in primary care. Annals of Family Medicine, 16(6), 515-520. doi: 10.1370/afm.2315

Stairmand, J., Gurney, J., Stanley, J., Millar, E., Davies, C., Semper, K., Dowell, A., Mangin, D., Lawrenson, R., & Sarfati, D. (2018). The impact of multimorbidity on people's lives: A cross-sectional survey. New Zealand Medical Journal, 131(1477), 78-90. Retrieved from https://www.nzma.org.nz/journal

Signal, L., Semper, K., Stairmand, J., Davies, C., Millar, E., Dowell, T., … Mangin, D., & Sarfati, D. (2017). A walking stick in one hand and a chainsaw in the other: Patients’ perspectives of living with multimorbidity. New Zealand Medical Journal, 130(1455), 65-76. Retrieved from https://www.nzma.org.nz/journal

Ailabouni, N., Mangin, D., & Nishtala, P. S. (2017). Can deprescribing give what polypharmacy has taken away? Feasibility trial in residential aged care. Innovation in Aging, 1(Suppl. 1), 588-589. doi: 10.1093/geroni/igx004.2065

Ailabouni, N., Mangin, D., Tordoff, J. M., & Nishtala, P. S. (2017). Do my patients need all their medicines? Registered nurses' views on deprescribing. Innovation in Aging, 1(Suppl. 1), 571. doi: 10.1093/geroni/igx004.2009

Ailabouni, N., Tordoff, J., Mangin, D., & Nishtala, P. S. (2017). Do residents need all their medications? A cross-sectional survey of RNs' views on deprescribing and the role of clinical pharmacists. Journal of Gerontological Nursing, 43(10), 13-20. doi: 10.3928/00989134-20170914-05

Ailabouni, N., Mangin, D., & Nishtala, P. S. (2017). Deprescribing anticholinergic and sedative medicines: Protocol for a feasibility trial (DEFEAT-polypharmacy) in residential aged care facilities. BMJ Open, 7(4), e013800. doi: 10.1136/bmjopen-2016-013800

Siu, H. Y.-H., Mangin, D., Howard, M., Price, D., & Chan, D. (2017). Developing and testing an electronic medication administration monitoring device for community dwelling seniors: A feasibility study. Pilot & Feasibility Studies, 3(1), 5. doi: 10.1186/s40814-016-0118-3

Healy, D., Le Noury, J., & Mangin, D. (2016). Links between serotonin reuptake inhibition during pregnancy and neurodevelopmental delay/spectrum disorders: A systematic review of epidemiological and physiological evidence. International Journal of Risk & Safety in Medicine, 28(3), 125-141. doi: 10.3233/JRS-160726

Dolovich, L., Oliver, D., Lamarche, L., Agarwal, G., Carr, T., Chan, D., … Mangin, D., … Price, D. (2016). A protocol for a pragmatic randomized controlled trial using the Health Teams Advancing Patient Experience: Strengthening Quality (Health TAPESTRY) platform approach to promote person-focused primary healthcare for older adults. Implementation Science, 11, 49. doi: 10.1186/s13012-016-0407-5

Ailabouni, N. J., Nishtala, P. S., Mangin, D., & Tordoff, J. M. (2016). Challenges and enablers of deprescribing: A general practitioner perspective. PLoS ONE, 11(4), e0151066. doi: 10.1371/journal.pone.0151066

Mangin, D., Stephen, G., Bismah, V., & Risdon, C. (2016). Making patient values visible in healthcare: A systematic review of tools to assess patient treatment priorities and preferences in the context of multimorbidity. BMJ Open, 6(6), e010903. doi: 10.1136/bmjopen-2015-010903

Ailabouni, N. J., Nishtala, P. S., Mangin, D., & Tordoff, J. M. (2016). General practitioners' insight into deprescribing for the multimorbid older individual: A qualitative study. International Journal of Clinical Practice, 70(3), 261-276. doi: 10.1111/ijcp.12780

Mangin, D., & Heath, I. (2015). Multimorbidity and quaternary prevention (P4). Revista Brasileira de Medicina de Família e Comunidade [Brazilian Journal of Family and Community Medicine], 10(35), 1-5. doi: 10.5712/rbmfc10(35)1069

Hogan, C., Le Noury, J., Healy, D., & Mangin, D. (2014). One hundred and twenty cases of enduring sexual dysfunction following treatment. International Journal of Risk & Safety in Medicine, 26(2), 109-116. doi: 10.3233/JRS-140617

Brookwell, L., Hogan, C., Healy, D., & Mangin, D. (2014). Ninety-three cases of alcohol dependence following SSRI treatment. International Journal of Risk & Safety in Medicine, 26(2), 99-107. doi: 10.3233/JRS-140616

Healy, D., Howe, G., Mangin, D., & Le Noury, J. (2014). Sudden cardiac death & the reverse Dodo verdict. International Journal of Risk & Safety in Medicine, 26(2), 71-79. doi: 10.3233/JRS-140615

Hudson, B., Toop, L., Mangin, D., Brunton, C., Jennings, L., & Fletcher, L. (2013). Pandemic influenza A(H1N1)pdm09: Risk of infection in primary healthcare workers. British Journal of General Practice, 63(611), e416-e422. doi: 10.3399/bjgp13X668212

Healy, D., Mangin, D., & Antonuccio, D. (2013). Data based medicine and clinical judgement. International Journal of Risk & Safety in Medicine, 25(2), 111-121. doi: 10.3233/JRS-130588

Currie, O., Mangin, D., Williman, J., McKinnon-Gee, B., & Bridgford, P. (2013). The comparative risk of new-onset diabetes after prescription of drugs for cardiovascular risk prevention in primary care: A national cohort study. BMJ Open, 3(11), e003475 . doi: 10.1136/bmjopen-2013-003475

Mangin, D., Murdoch, D., Wells, J. E., Coughlan, E., Bagshaw, S., Corwin, P., Chambers, S., & Toop, L. (2012). Chlamydia trachomatis testing sensitivity in midstream compared with first-void urine specimens. Annals of Family Medicine, 10(1), 50-53. doi: 10.1370/afm.1323

Caplan, G. A., Sulaiman, N. S., Mangin, D. A., Ricauda, N. A., Wilson, A. D., & Barclay, L. (2012). A meta-analysis of "hospital in the home". Medical Journal of Australia, 197(9), 512-519. doi: 10.5694/mja12.10480

Starfield, B., Gérvas, J., & Mangin, D. (2012). Clinical care and health disparities. Annual Review of Public Health, 33(1), 89-106. doi: 10.1146/annurev-publhealth-031811-124528

Gill, E., & Mangin, D. (2011). Can general practitioners provide effective cardiovascular disease (CVD) prevention? Dreams and realities of CVD prevention. New Zealand Medical Journal, 124(1328). Retrieved from http://journal.nzma.org.nz/journal/124-1328/4506/content.pdf

Hudson, B., Toop, L., Mangin, D., & Pearson, J. (2011). Risk communication methods in hip fracture prevention: A randomised trial in primary care. British Journal of General Practice, 61(589), e469-e476. doi: 10.3399/bjgp11X588439

Starfield, B., & Mangin, D. (2010). An international perspective on the basis for payment for performance. Quality in Primary Care, 18(6), 399-404.

Mangin, D. (2010). All people over 75 years with a five-year CVD risk of ≥15% should be treated with statins unless specifically contraindicated: The 'no' case. Journal of Primary Health Care, 2(4), 333-335.

Garfinkel, D., & Mangin, D. (2010). Feasibility study of a systematic approach for discontinuation of multiple medications in older adults: Addressing polypharmacy. Archives of Internal Medicine, 170(18), 1648-1654. doi: 10.1001/archinternmed.2010.355

Healy, D., Mangin, D., & Mintzes, B. (2010). The ethics of randomized placebo controlled trials of antidepressants with pregnant women. International Journal of Risk & Safety in Medicine, 22(1), 7-16. doi: 10.3233/JRS-2010-0487

Wilson, K., Dowson, C., & Mangin, D. (2007). Prevalence of complementary and alternative medicine use in Christchurch, New Zealand: Children attending general practice versus paediatric outpatients. New Zealand Medical Journal, 120(1251). Retrieved from http://journal.nzma.org.nz/journal/120-1251/2464/content.pdf

Mangin, D., Sweeney, K., & Heath, I. (2007). Preventive health care in elderly people needs rethinking. BMJ, 335, 285-287. doi: 10.1136/bmj.39241.630741.BE1

Gill, E. A., Corwin, P. A., Mangin, D. A., & Sutherland, M. G. (2006). Diabetes care in rest homes in Christchurch, New Zealand. Diabetic Medicine, 23, 1252-1256.

Corwin, P., Toop, L., McGeoch, G., Than, M., Wynn-Thomas, S., Wells, J. E., Dawson, R., … Pithie, A., Chambers, S., Fletcher, L., & Richards, D. (2005). Randomised controlled trial of intravenous antibiotic treatment for cellulitis at home compared with hospital. British Medical Journal, 330(7483). Retrieved from http://www.bmj.com/cgi/reprint/330/7483/129

Richards, D. A., Toop, L. J., Epton, M. J., McGeoch, G. R. B., Town, G. I., Wynn-Thomas, S. M. H., Dawson, R. D., Hlavac, M. C., Werno, A. M., & Abernethy, P. D. (2005). Home management of mild to moderately severe community-acquired pneumonia: A randomised controlled trial. Medical Journal of Australia, 183(5), 235-238.

Richards, D., Toop, L., Chambers, S., & Fletcher, L. (2005). Response to antibiotics of women with symptoms of urinary tract infection but negative dipstick urine test results: Double blind randomised controlled trial. British Medical Journal, 331(7509). Retrieved from http://bmj.bmjjournals.com/cgi/content/abstract/331/7509/143

Mangin, D., Toop, L., Chambers, S., Ikram, R., & Harris, B. (2005). Increased rates of trimethoprim resistance in uncomplicated urinary tract infection: Cause for concern? New Zealand Medical Journal, 118(1225). Retrieved from http://journal.nzma.org.nz/journal/118-1225/1726/content.pdf

Richards, D. A., Toop, L. J., & Graham, P. J. (2003). Do clinical practice education groups result in sustained change in GP prescribing? Family Practice, 20(2), 199-206.

Richards, D., Toop, L., Brockway, K., Graham, S., McSweeney, B., MacLean, D., … Parsons, A. (2003). Improving the effectiveness of smoking cessation in primary care: Lessons learned. New Zealand Medical Journal, 116(1173). Retrieved from http://journal.nzma.org.nz/journal/116-1173/417/content.pdf

Richards, D. A., Toop, L. J., Chambers, S., Sutherland, M. G., Harris, B., Ikram, R., … Peddie, B. A. (2002). Antibiotic resistance in uncomplicated urinary tract infection: Problems with interpreting cumulative resistance rates from local community laboratories. New Zealand Medical Journal, 115(1146), 12-14.

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Journal - Research Other

Millar, E., Dowell, A., Lawrenson, R., Mangin, D., & Sarfati, D. (2018). Clinical guidelines: What happens when people have multiple conditions? New Zealand Medical Journal, 131(1472), 73-81. Retrieved from https://www.nzma.org.nz/journal

Swinburn, B., Vandevijvere, S., on behalf of submitting health professors, including Hornblow, A., Taylor, B., Drummond, B., Murdoch, D., Mangin, D., Sarfati, D., Sellman, D., Sopoaga, F., Thomson, G., Abel, G., Hoek, J., Connor, J., Krebs, J., Mann, J., McCall, J., Broughton, J., Toop, L., Signal, L., Beckert, L., Farella, M., Baker, M., Keall, M., Skeaff, M., Thomson, M., Wilson, N., Chandler, N., Priest, P., Brunton, P., Crampton, P., Gendall, P., Howden-Chapman, P., Taylor, R., Edwards, R., Gauld, R., McGee, R., Mulder, R., Derrett, S., Hales, S., Pullon, S., & Blakely, T. (2017). Proposed new industry code on unhealthy food marketing to children and young people: Will it make a difference? New Zealand Medical Journal, 130(1450), 94-101. Retrieved from http://www.nzma.org.nz/journal

Birtwhistle, R., Barber, D., Drummond, N., Godwin, M., Greiver, M., Singer, A., … Mangin, D. (2015). Horses and buggies have some advantages over cars, but no one is turning back. Canadian Family Physician, 61(5), 416-418. [Letter].

Toop, L., & Mangin, D. (2015). The art and science of marketing medications. New Zealand Medical Journal, 128(1421). Retrieved from https://www.nzma.org.nz/journal

Hudson, B., Williman, J. A., Stamp, L. K., Alchin, J. S., Hooper, G. J., Mangin, D., Thompson, B. F., & Toop, L. (2015). Nortriptyline in knee osteoarthritis (NortIKA Study): Study protocol for a randomised controlled trial. Trials, 16, 448. doi: 10.1186/s13063-015-0961-1

Mangin, D. (2014). Ethical issues related to health checks. BMJ, 349, g4787. doi: 10.1136/bmj.g4787

Healy, D., Mangin, D., & Applbaum, K. (2014). The shipwreck of the singular. Social Studies of Science, 44(4), 518-523. doi: 10.1177/0306312714536270

da Silva, A. L., Mangin, D., Pizzanelli, M., Jamoulle, M., Wagner, H. L., De Silva, D. H. S., … Júnior, W. R. (2014). Manifesto de Curitaba: pela Prevenção Quaternária e por uma Medicin sem conflitos de interesse [The Curitiba Manifesto: for the quaternary prevention and for a medical practice without conflicts of interest. Revista Brasileira de Medicina de Família e Comunidade [Brazilian Journal of Family and Community Medicine], 9(33), 371-374. doi: 10.5712/rbmfc9(33)1006

Mangin, D. (2013). Commentary on Review: Cranberry products do not reduce urinary tract infections in susceptible populations. Annals of Internal Medicine, 158(10), JC11. [Commentary].

Mangin, D. (2012). Adherence to evidence-based guidelines is the key to improved health outcomes for general practice patients: The 'no' case. Journal of Primary Health Care, 4(2), 158-160. [Commentary].

Mangin, D., Hudson, B., & Toop, L. (2012). Direct-to-consumer genetic testing: Letting the genie out of the bottle? New Zealand Medical Journal, 125(1364). Retrieved from http://www.nzma.org.nz/journal

Mangin, D., Heath, I., & Jamoulle, M. (2012). Beyond diagnosis: Rising to the multimorbidity challenge. BMJ, 344, e3526. doi: 10.1136/bmj.e3526

Heath, I., Mangin, D., Toop, L., & Brodersen, J. (2011). The future of national health systems [Editorial]. British Journal of General Practice, 61(586), 319-320. doi: 10.3399/bjgp11X572292

Mangin, D., Healy, D., & Mintzes, B. (2011). Paroxetine is associated with malformation during pregnancy [Letter]. BMJ, 343, d5060. doi: 10.1136/bmj.d5060

Garfinkel, D., & Mangin, D. (2011). In reply to Reducing polypharmacy: Is hospitalization the right time? [Editor's correspondence]. Archives of Internal Medicine, 171(9), 870. doi: 10.1001/archinternmed.2011.209

Urato, A., Mintzes, B., Mangin, D., & Jureidini, J. (2011). [Letter to the editor about the article Diagnosis, pathophysiology, and management of mood disorders in pregnant and postpartum women]. Obstetrics & Gynecology, 118(3), 708. doi: 10.1097/AOG.0b013e31822bd7e3

Mangin, D. (2010). Urinary tract infection in primary care [Editorial]. BMJ, 340, c657. doi: 10.1136/bmj.c657

Healy, D., & Mangin, D. (2009). The once and future psychiatry [Commentary]. Academic Medicine, 84(4), 418-420.

Toop, L., & Mangin (Richards), D. (2009). [Commentary to A dipstick clinical prediction rule modestly improved diagnostic precision in women with suspected urinary tract infection]. Evidence-Based Medicine, 14(5), 155. doi: 10.1136/ebm.14.5.155

Mintzes, B., & Mangin, D. (2009). Direct-to-consumer advertising of prescription medicines: A counter argument. Future Medicinal Chemistry, 1(9), 1555-1560. doi: 10.4155/fmc.09.136

Mangin, D., & Toop, L. (2007). The quality and outcomes framework: What have you done to yourselves? [Editorial]. British Journal of General Practice, 57(539), 435-437.

Mangin, D., & Toop, L. (2007). Urinary tract infection in primary care. BMJ, 334, 597-598. doi: 10.1136/bmj.39148.403206.80

Toop, L., & Mangin, D. (2007). Industry funded patient information and the slippery slope to New Zealand. BMJ, 335, 694-695. doi: 10.1136/bmj.39346.525764.AD

Mangin, D. (2006). Management of uncertainty [Commentary]. BMJ, 333, 693. doi: 10.1136/bmj.38978.491667.68

Toop, L., Richards, D., & Dowell, T. (2005). Response to Maubach and Hoek's paper on GP attitudes to DTCA [Letter]. New Zealand Medical Journal, 118(1217). Retrieved from http://journal.nzma.org.nz/journal/118-1217/1543/content.pdf

Mansfield, P. R., Mintzes, B., Richards, D., & Toop, L. (2005). Direct to consumer advertising: Is at the crossroads of competing pressures from industry and health needs [Editorial]. BMJ, 330(7481), 5-6. doi: 10.1136/bmj.330.7481.5

Toop, L., & Richards, D. (2004). Physicians' negative views of direct-to-consumer advertising (DTCA): The international evidence grows [Editorial]. New Zealand Medical Journal, 117(1195). Retrieved from http://journal.nzma.org.nz/journal/117-1195/905/content.pdf

Toop, L. J., Richards, D. A., & Dowell, A. C. (2003). The leadership role of general practice in public health: Advocating a ban of direct-to-consumer advertising of prescription drugs in New Zealand. 'Possums in the headlights?'. British Journal of General Practice, 53(489), 342-345.

Toop, L. J., & Richards, D. A. (2002). DTCA in New Zealand: The challenge of finding an acceptable balance. British Journal of General Practice, 52(477), 341.

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