Accessibility Skip to Global Navigation Skip to Local Navigation Skip to Content Skip to Search Skip to Site Map Menu

Otago Medical School staff profiles

Dr Manuela Centanni

PositionPostdoctoral Fellow
DepartmentDepartment of Microbiology and Immunology
QualificationsPhD
Research summaryGastrointestinal Microbiology

Research

Manuela works with Prof Gerald Tannock. Her research interests include:
- gut microbiology
- molecular microbiology
- culture and characterisation of members of the gut microbiota

Publications

Centanni, M., Ferguson, S. A., Sims, I. M., Biswas, A., & Tannock, G. W. (2019). Bifidobacterium bifidum ATCC 15696 and Bifidobacterium breve 24b metabolic interaction based on 2'-O-fucosyl-lactose studied in steady-state cultures in a Freter-style chemostat. Applied & Environmental Microbiology. Advance online publication. doi: 10.1128/aem.02783-18

Centanni, M., Lawley, B., Butts, C. A., Roy, N. C., Lee, J., Kelly, W. J., & Tannock, G. W. (2018). Bifidobacterium pseudolongum in the ceca of rats fed Hi-Maize starch has characteristics of a keystone species in bifidobacterial blooms. Applied & Environmental Microbiology, 84(15), e00547-18. doi: 10.1128/AEM.00547-18

Lawley, B., Centanni, M., Watanabe, J., Sims, I., Carnachan, S., Broadbent, R., Lee, P. S., … Tannock, G. W. (2018). Tuf gene sequence variation in Bifidobacterium longum subspecies infantis detected in the fecal microbiota of Chinese infants. Applied & Environmental Microbiology. Advance online publication. doi: 10.1128/aem.00336-18

Bell, T. J., Draper, S. L., Centanni, M., Carnachan, S. M., Tannock, G. W., & Sims, I. M. (2018). Characterization of polysaccharides from feijoa fruits (Acca sellowiana Berg.) and their utilization as growth substrates by gut commensal Bacteroides species. Journal of Agricultural & Food Chemistry, 66(50), 13277-13284. doi: 10.1021/acs.jafc.8b05080

Centanni, M., Lawley, B., Butts, C. A., Roy, N., Lee, J., Kelly, W. J., & Tannock, G. W. (2018). Bifidobacterium pseudolongum has characteristics of a keystone species in bifidobacterial blooms in the ceca of rats fed Hi-Maize starch. Applied & Environmental Microbiology. Advance online publication. doi: 10.1128/aem.00547-18

Journal - Research Article

Centanni, M., Ferguson, S. A., Sims, I. M., Biswas, A., & Tannock, G. W. (2019). Bifidobacterium bifidum ATCC 15696 and Bifidobacterium breve 24b metabolic interaction based on 2'-O-fucosyl-lactose studied in steady-state cultures in a Freter-style chemostat. Applied & Environmental Microbiology. Advance online publication. doi: 10.1128/aem.02783-18

Centanni, M., Lawley, B., Butts, C. A., Roy, N. C., Lee, J., Kelly, W. J., & Tannock, G. W. (2018). Bifidobacterium pseudolongum in the ceca of rats fed Hi-Maize starch has characteristics of a keystone species in bifidobacterial blooms. Applied & Environmental Microbiology, 84(15), e00547-18. doi: 10.1128/AEM.00547-18

Centanni, M., Lawley, B., Butts, C. A., Roy, N., Lee, J., Kelly, W. J., & Tannock, G. W. (2018). Bifidobacterium pseudolongum has characteristics of a keystone species in bifidobacterial blooms in the ceca of rats fed Hi-Maize starch. Applied & Environmental Microbiology. Advance online publication. doi: 10.1128/aem.00547-18

Bell, T. J., Draper, S. L., Centanni, M., Carnachan, S. M., Tannock, G. W., & Sims, I. M. (2018). Characterization of polysaccharides from feijoa fruits (Acca sellowiana Berg.) and their utilization as growth substrates by gut commensal Bacteroides species. Journal of Agricultural & Food Chemistry, 66(50), 13277-13284. doi: 10.1021/acs.jafc.8b05080

Lawley, B., Centanni, M., Watanabe, J., Sims, I., Carnachan, S., Broadbent, R., Lee, P. S., … Tannock, G. W. (2018). Tuf gene sequence variation in Bifidobacterium longum subspecies infantis detected in the fecal microbiota of Chinese infants. Applied & Environmental Microbiology. Advance online publication. doi: 10.1128/aem.00336-18

Centanni, M., Hutchinson, J. C., Carnachan, S. M., Daines, A. M., Kelly, W. J., Tannock, G. W., & Sims, I. M. (2017). Differential growth of bowel commensal Bacteroides species on plant xylans of differing structural complexity. Carbohydrate Polymers, 157, 1374-1382. doi: 10.1016/j.carbpol.2016.11.017

De Fazio, L., Spisni, E., Cavazza, E., Strillacci, A., Candela, M., Centanni, M., … Valerii, M. C. (2016). Dietary geraniol by oral or enema administration strongly reduces dysbiosis and systemic inflammation in dextran sulfate sodium-treated mice. Frontiers in Pharmacology, 7, 38. doi: 10.3389/fphar.2016.00038

Turroni, S., Rampelli, S., Centanni, M., Schnorr, S. L., Consolandi, C., Severgnini, M., … Candela, M. (2016). Enterocyte-associated microbiome of the Hadza hunter-gatherers. Frontiers in Microbiology, 7, 865. doi: 10.3389/fmicb.2016.00865

Spisni, E., Valerii, M. C., De Fazio, L., Cavazza, E., Borsetti, F., Sgromo, A., … Centanni, M., … Strillacci, A. (2015). Cyclooxygenase-2 silencing for the treatment of colitis: A combined in vivo strategy based on RNA interference and engineered Escherichia coli. Molecular Therapy, 23(2), 278-289. doi: 10.1038/mt.2014.222

Consolandi, C., Turroni, S., Emmi, G., Severgnini, M., Fiori, J., Peano, C., … Centanni, M., … D'Elios, M. M. (2015). Behçet's syndrome patients exhibit specific microbiome signature. Autoimmunity Reviews, 14(4), 269-276. doi: 10.1016/j.autrev.2014.11.009

Biagi, E., Zama, D., Nastasi, C., Consolandi, C., Fiori, J., Rampelli, S., … Centanni, M., … Candela, M. (2015). Gut microbiota trajectory in pediatric patients undergoing hematopoietic SCT. Bone Marrow Transplantation, 50, 992-998. doi: 10.1038/bmt.2015.16

De Fazio, L., Cavazza, E., Spisni, E., Strillacci, A., Centanni, M., Candela, M., … Valerii, M. C. (2014). Longitudinal analysis of inflammation and microbiota dynamics in a model of mild chronic dextran sulfate sodium-induced colitis in mice. World Journal of Gastroenterology, 20(8), 2051-2061. doi: 10.3748/wjg.v20.i8.2051

Biagi, E., Candela, M., Centanni, M., Consolandi, C., Rampelli, S., Turroni, S., … Brigidi, P. (2014). Gut microbiome in Down Syndrome. PLoS ONE, 9(11), e112023. doi: 10.1371/journal.pone.0112023

Schnorr, S. L., Candela, M., Rampelli, S., Centanni, M., Consolandi, C., Basaglia, G., … Crittenden, A. N. (2014). Gut microbiome of the Hadza hunter-gatherers. Nature Communications, 5, 3654. doi: 10.1038/ncomms4654

Centanni, M., Turroni, S., Rampelli, S., Biagi, E., Quercia, S., Consolandi, C., … Candela, M. (2014). Bifidobacterium animalis ssp. lactis BI07 modulates the tumor necrosis factor alpha-dependent imbalances of the enterocyte-associated intestinal microbiota fraction. FEMS Microbiology Letters, 357(2), 157-163. doi: 10.1111/1574-6968.12515

Centanni, M., Turroni, S., Consolandi, C., Rampelli, S., Peano, C., Severgnini, M., … Candela, M. (2013). The enterocyte-associated intestinal microbiota of breast-fed infants and adults responds differently to a TNF-α-mediated pro-inflammatory stimulus. PLoS ONE, 8(11), e81762. doi: 10.1371/journal.pone.0081762

Centanni, M., Turroni, S., Biagi, E., Severgnini, M., Consolandi, C., Brigidi, P., & Candela, M. (2013). A novel combined approach based on HTF-Microbi.Array and qPCR for a reliable characterization of the Bifidobacterium-dominated gut microbiota of breast-fed infants. FEMS Microbiology Letters, 343, 121-126. doi: 10.1111/1574-6968.12138

Centanni, M., Bergmann, S., Turroni, S., Hammerschmidt, S., Chhatwal, G. S., Brigidi, P., & Candela, M. (2012). Tumor necrosis factor alpha modulates the dynamics of the plasminogen-mediated early interaction between Bifidobacterium animalis subsp. lactis and human enterocytes. Applied & Environmental Microbiology, 78(7), 2465-2469. doi: 10.1128/AEM.07883-11

Maccaferri, S., Candela, M., Turroni, S., Centanni, M., Severgnini, M., Consolandi, C., … Brigidi, P. (2012). IBS-associated phylogenetic unbalances of the intestinal microbiota are not reverted by probiotic supplementation. Gut Microbes, 3(5), 406-413. doi: 10.4161/gmic.21009

More publications...