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Otago Medical School staff profiles

Associate Professor Peter Larsen

PositionAssociate Professor and Head of Department
DepartmentsDepartment of Radiation Therapy (UOW), Department of Surgery and Anaesthesia (Wellington)
QualificationsBSc(Hons), PhD (Otago)
Research summaryClinical cardiovascular medicine

Research

After completing a BSc with Honours at Victoria University of Wellington, I undertook a PhD at the University of Otago. This focused on understanding the interactions between cardiovascular and respiratory control. I then did a postdoctoral fellowship at Michigan State University examined neural control of the cardiovascular system, before returning to the University of Otago, Wellington.

My research interests are now in clinical cardiovascular medicine, including the use of biomarkers in risk stratification, acute myocardial infarction, use of implanted cardiac devices and personalized approaches to clinical care. Application of cardiovascular physiology to clinical questions remains an area of interest for me. In addition, I am involved in supporting registrar research activities in a range of clinical settings.

Publications

Hally, K. E., Holley, A. S., Kristono, G. A., Harding, S. A., & Larsen, P. D. (2019). Immunoglobulin G levels predicts risk of recurrent adverse cardiovascular events in myocardial infarction patients. Acta Cardiologica. Advance online publication. doi: 10.1080/00015385.2019.1611189

Foo, F. S., Lee, M., Heaven, D., Lever, N., Sinclair, S., Stiles, M. K., Harding, S., … Larsen, P., … on behalf of the ANZACS-QI investigators. (2019). Completeness of ANZACS-QI Cardiac Implanted DEVICE Registry and agreement with national datasets: ANZACS-QI 30. New Zealand Medical Journal, 132(1500), 40-49. Retrieved from https://www.nzma.org.nz/journal

de Burlet, K. J., Lam, A. B. M., Harper, S. J., Larsen, P. D., & Dennett, E. R. (2019). Can surgical registrars accurately identify the urgent from the non-urgent patient presenting with acute abdominal pain? European Surgical Research, 60(1-2), 24-30. doi: 10.1159/000496021

Bond, E. C., Phillips, P., Larsen, P. D., Hunt, L., & Willoughby, R. (2019). Long-term hip function in slipped capital femoral epiphysis treated with in situ pinning. Journal of Orthopaedic Surgery, 27(1), 1-6. doi: 10.1177/2309499018822234

Wilkins, B., Hullikunte, S., Simmonds, M., Sasse, A., Larsen, P., & Harding, S. A. (2019). Improving the prescribing gap for guideline recommended medications post myocardial infarction. Heart, Lung & Circulation, 28(2), 257-262. doi: 10.1016/j.hlc.2017.10.025

Journal - Research Article

Hally, K. E., Holley, A. S., Kristono, G. A., Harding, S. A., & Larsen, P. D. (2019). Immunoglobulin G levels predicts risk of recurrent adverse cardiovascular events in myocardial infarction patients. Acta Cardiologica. Advance online publication. doi: 10.1080/00015385.2019.1611189

Wilkins, B., Hullikunte, S., Simmonds, M., Sasse, A., Larsen, P., & Harding, S. A. (2019). Improving the prescribing gap for guideline recommended medications post myocardial infarction. Heart, Lung & Circulation, 28(2), 257-262. doi: 10.1016/j.hlc.2017.10.025

Bond, E. C., Phillips, P., Larsen, P. D., Hunt, L., & Willoughby, R. (2019). Long-term hip function in slipped capital femoral epiphysis treated with in situ pinning. Journal of Orthopaedic Surgery, 27(1), 1-6. doi: 10.1177/2309499018822234

de Burlet, K. J., Lam, A. B. M., Harper, S. J., Larsen, P. D., & Dennett, E. R. (2019). Can surgical registrars accurately identify the urgent from the non-urgent patient presenting with acute abdominal pain? European Surgical Research, 60(1-2), 24-30. doi: 10.1159/000496021

Foo, F. S., Lee, M., Heaven, D., Lever, N., Sinclair, S., Stiles, M. K., Harding, S., … Larsen, P., … on behalf of the ANZACS-QI investigators. (2019). Completeness of ANZACS-QI Cardiac Implanted DEVICE Registry and agreement with national datasets: ANZACS-QI 30. New Zealand Medical Journal, 132(1500), 40-49. Retrieved from https://www.nzma.org.nz/journal

Hancock, D. S., Rupasinghe, S. L., Elkinson, I., Bloomfield, M. G., & Larsen, P. D. (2018). Benzoyl peroxide + chlorhexidine versus chlorhexidine alone skin preparation to reduce Propionibacterium acnes: A randomized controlled trial. ANZ Journal of Surgery. Advance online publication. doi: 10.1111/ans.14848

Hally, K. E., La Flamme, A. C., Harding, S. A., & Larsen, P. D. (2018). Platelets regulate leucocyte responses to Toll-like receptor stimulation. Clinical & Translational Immunology, 7, e1036. doi: 10.1002/cti2.1036

Gunawardene, A., Larsen, P., Shekouh, A., & Dennett, E. (2018). Pre-operative carcinoembryonic antigen predicts survival following colorectal cancer surgery with curative intent. ANZ Journal of Surgery. Advance online publication. doi: 10.1111/ans.14723

de Burlet, K. J., Desmond, B., Harper, S. J., Larsen, P. D., & Dennett, E. R. (2018). Patients requiring an acute operation: Where are the delays in the process? ANZ Journal of Surgery. Advance online publication. doi: 10.1111/ans.14718

Hancock, D. S., Sharplin, P. K., Larsen, P. D., & Phillips, F. T. S. (2018). Early radiological and functional outcomes for a cementless press-fit design modular femoral stem revision system. HIP International. Advance online publication. doi: 10.1177/1120700018760277

de Burlet, K. J., MacKay, M., Larsen, P., & Dennett, E. R. (2018). Appropriateness of CT scans for patients with non-traumatic acute abdominal pain. British Journal of Radiology, 91(1088), 20180158. doi: 10.1259/bjr.20180158

Hally, K. E., La Flamme, A. C., Harding, S. A., & Larsen, P. D. (2018). The effects of aspirin and ticagrelor on Toll-like receptor (TLR)-mediated platelet activation: Results of a randomized, cross-over trial. Platelets. Advance online publication. doi: 10.1080/09537104.2018.1479520

Ady Wirawan, I. M., Griffiths, R. F., & Larsen, P. D. (2018). Cardiovascular tests for risk assessment in asymptomatic adults and implications for pilots. Aerospace Medicine & Human Performance, 89(7), 648-656. doi: 10.3357/amhp.5065.2018

Tinawi, G., Gunawardene, A., Shekouh, A., Larsen, P. D., & Dennett, E. R. (2018). Neoadjuvant therapy in rectal cancer: How are we choosing? ANZ Journal of Surgery. Advance online publication. doi: 10.1111/ans.14935

O'Connor, M., Hooks, D., Webber, M., Shi, B., Morrison, S., Harding, S., & Larsen, P. (2018). Long-term single-center comparison of ICD lead survival: Evidence for premature Linox lead failure. Journal of Cardiovascular Electrophysiology. Advance online publication. doi: 10.1111/jce.13502

Gunawardene, A., Desmond, B., Shekouh, A., Larsen, P., & Dennett, E. (2018). Disease recurrence following surgery for colorectal cancer: Five-year follow-up. New Zealand Medical Journal, 131(1469), 51-58. Retrieved from https://www.nzma.org.nz/journal

Larsen, P. D., Holley, A. S., Sasse, A., Al-Sinan, A., Fairley, S., & Harding, S. A. (2017). Comparison of Multiplate and VerifyNow platelet function tests in predicting clinical outcome in patients with acute coronary syndromes. Thrombosis Research, 152, 14-19. doi: 10.1016/j.thromres.2017.02.006

Harding, S. A., Holley, A., Wilkins, B., Fairley, S., Simmonds, M., & Larsen, P. D. (2017). Contemporary antiplatelet therapy in acute coronary syndromes: Are there differences in outcomes and discontinuation between clopidogrel and ticagrelor? Internal Medicine Journal, 47(11), 1298-1305. doi: 10.1111/imj.13595

Roberts, T., Campbell, A., Larsen, P., & Elder, D. (2017). Preterm infants at discharge: Nap polysomnography versus 24-hour oximetry. Acta Paediatrica, 106(111), 1754-1759. doi: 10.1111/apa.13900

Shi, B., Harding, S., & Larsen, P. (2017). Analysis of ECG measures of cardiac repolarization in relation to arrhythmic events in an implantable cardioverter defibrillator population. Annals of Noninvasive Electrocardiology, 22(2), e12390. doi: 10.1111/anec.12390

Holley, A., Pitman, J., Miller, J., Harding, S., & Larsen, P. (2017). Glutathione peroxidase activity and expression levels are significantly increased in acute coronary syndromes. Journal of Investigative Medicine, 65(5), 919-925. doi: 10.1136/jim-2016-000361

Hally, K. E., La Flamme, A. C., Larsen, P. D., & Harding, S. A. (2017). Platelet Toll-like receptor (TLR) expression and TLR-mediated platelet activation in acute myocardial infarction. Thrombosis Research, 158, 8-15. doi: 10.1016/j.thromres.2017.07.031

de Burlet, K., Lam, A., Larsen, P., & Dennett, E. (2017). Acute abdominal pain: Changes in the way we assess it over a decade. New Zealand Medical Journal, 130(1463), 39-44. Retrieved from https://www.nzma.org.nz/journal

Matsis, K., Holley, A., Al-Sinan, A., Matsis, P., Larsen, P. D., & Harding, S. A. (2017). Differing clinical characteristics between young and older patients presenting with myocardial infarction. Heart, Lung & Circulation, 26(6), 566-571. doi: 10.1016/j.hlc.2016.09.007

Larsen, P. D., Kerr, A. J., Hood, M., Harding, S. A., Hooks, D., Heaven, D., … on behalf of the ANZACS-QI Investigators. (2017). Pacemaker use in New Zealand: Data from the New Zealand Implanted Cardiac Device Registry (ANZACS-QI 15). Heart, Lung & Circulation, 26(3), 235-239. doi: 10.1016/j.hlc.2016.06.1206

Hally, K. E., La Flamme, A. C., Larsen, P. D., & Harding, S. A. (2016). Toll-like receptor 9 expression and activation in acute coronary syndrome patients on dual anti-platelet therapy. Thrombosis Research, 148, 89-95. doi: 10.1016/j.thromres.2016.10.026

Fake, A. L., Harding, S. A., Matsis, P. P., & Larsen, P. D. (2016). Pharmacological therapy following acute coronary syndromes in patients with atrial fibrillation: How do we balance ischaemic risk with bleeding risk? New Zealand Medical Journal, 129(1435), 39-49. Retrieved from https://www.nzma.org.nz/journal

Holley, A. S., Miller, J. H., Larsen, P. D., & Harding, S. A. (2016). Relationship between glutathione peroxidase, platelet reactivity, and reactive oxygen species in an acute coronary syndrome population. Annals of Clinical & Laboratory Science, 46(6), 639-644.

Nichol, G., Brown, S. P., Perkins, G. D., Kim, F., Sterz, F., Elrod, J. A. B., … Larsen, P., … Sayre, M. (2016). What change in outcomes after cardiac arrest is necessary to change practice? Results of an international survey. Resuscitation, 107, 115-120. doi: 10.1016/j.resuscitation.2016.08.004

Wolbinski, M., Swain, A. H., Harding, S. A., & Larsen, P. D. (2016). Out-of-hospital cardiac arrest patient characteristics: Comparing ventricular arrthymia and pulseless electrical activity. Heart, Lung & Circulation, 25(7), 639-644. doi: 10.1016/j.hlc.2016.02.001

Holley, A., Harding, S., Sasse, A., Miller, J., & Larsen, P. (2016). Reduced glutathione peroxidase activity predicts increased cardiovascular risk following an acute coronary syndrome. International Cardiovascular Forum Journal, 6, 61-65. doi: 10.17987/icfj.v6i0.241

Johnston, J. W., Larsen, P., El-Haddawi, F. H., Fancourt, M. W., Farrant, G. J., Gilkison, W. T. C., … Mosquera, D. A. (2015). Time delays in presentation and treatment of acute scrotal pain in a provincial hospital. ANZ Journal of Surgery, 85(5), 330-333. doi: 10.1111/ans.12601

Larsen, P. D., Johnston, L. R., Holley, A., La Flamme, A., Smyth, L., Chua, E. W., Kennedy, M. A., & Harding, S. A. (2015). Prevalence and significance of CYP2C19*2 and CYP2C19*17 alleles in a New Zealand acute coronary syndrome population. Internal Medicine Journal, 45(5), 537-545. doi: 10.1111/imj.12698

Furniss, G., Shi, B., Jimenez, A., Harding, S. A., & Larsen, P. D. (2015). Cardiac troponin levels following implantable cardioverter defibrillation implantation and testing. Europace, 17(2), 262-266. doi: 10.1093/europace/euu306

Webb, I. G., Yam, S. T., Cooke, R., Aitken, A., Larsen, P. D., & Harding, S. A. (2015). Elevated baseline cardiac troponin levels in the elderly: Another variable to consider? Heart, Lung & Circulation, 24(2), 142-148. doi: 10.1016/j.hlc.2014.07.071

Shi, B., Ferrier, K. A., Sasse, A., Harding, S. A., & Larsen, P. D. (2014). Correlation between vectorcardiographic measures and cardiac magnetic resonance imaging of the left ventricle in an implantable cardioverter defibrillator population. Journal of Electrocardiology, 47(1), 52-58. doi: 10.1016/j.jelectrocard.2013.06.018

Ady Wirawan, I. M., Wu, R., Abernethy, M., Aldington, S., & Larsen, P. D. (2014). Calcium scores in the risk assessment of an asymptomatic population: Implications for airline pilots. Aviation, Space, & Environmental Medicine, 85(8), 812-817. doi: 10.3357/ASEM.3904.2014

Harding, S. A., Shah, N., Briggs, N., Sasse, A., & Larsen, P. D. (2013). Complex transradial percutaneous coronary intervention using a sheathless guide catheter. Heart, Lung & Circulation, 22(3), 188-192. doi: 10.1016/j.hlc.2012.10.004

Johnston, L. R., Larsen, P. D., La Flamme, A. C., & Harding, S. A. (2013). Methodological considerations for the assessment of ADP induced platelet aggregation using the Multiplate® analyser. Platelets, 24(4), 303-307. doi: 10.3109/09537104.2012.694086

Ady Wirawan, I. M., Aldington, S., Griffiths, R. F., Ellis, C. J., & Larsen, P. D. (2013). Cardiovascular investigations of airline pilots with excessive cardiovascular risk. Aviation, Space, & Environmental Medicine, 84(6), 608-612. doi: 10.3357/ASEM.3465.2013

Shi, B., Harding, S. A., Jimenez, A., & Larsen, P. D. (2013). Standard 12-lead electrocardiography measures predictive of increased appropriate therapy in implantable cardioverter defibrillator recipients. Europace, 15(6), 892-898. doi: 10.1093/europace/eus360

Fake, A. L., Swain, A. H., & Larsen, P. D. (2013). Survival from out-of-hospital cardiac arrest in Wellington in relation to socioeconomic status and arrest location. New Zealand Medical Journal, 126(1376). Retrieved from http://www.nzma.org.nz/journal

Johnston, L. R., Larsen, P. D., La Flamme, A. C., Michel, J. M., Simmonds, M. B., & Harding, S. A. (2013). Suboptimal response to clopidogrel and the effect of prasugrel in acute coronary syndromes. International Journal of Cardiology, 167(3), 995-999. doi: 10.1016/j.ijcard.2012.03.080

Tomkins, W. G. O., Swain, A. H., Bailey, M., & Larsen, P. D. (2013). Beyond the pre-shock pause: The effect of prehospital defibrillation mode on CPR interruptions and return of spontaneous circulation. Resuscitation, 84, 575-579. doi: 10.1016/j.resuscitation.2012.12.018

Elder, D. E., Larsen, P. D., Campbell, A. J., & Galletly, D. C. (2012). Cardioventilatory coupling and inter-breath variability in children referred for polysomnography. Respiratory Physiology & Neurobiology, 181(1), 1-7. doi: 10.1016/j.resp.2012.01.006

Swain, A. H., Al-Salami, M., Larsen, P. D., & Hoyle, S. R. (2012). Patient satisfaction and outcome using emergency care practitioners in New Zealand. Emergency Medicine Australasia, 24(2), 175-180. doi: 10.1111/j.1742-6723.2011.01525.x

Hoyle, S., Swain, A. H., Fake, P., & Larsen, P. D. (2012). Introduction of an extended care paramedic model in New Zealand. Emergency Medicine Australasia, 24(6), 652-656. doi: 10.1111/j.1742-6723.2012.01608.x

Zaidi, M. A., Griffiths, R. F., Larsen, P. D., Newson-Smith, M., & Zaidi, M. A. (2012). The reporting of blood and body fluid exposure and follow-up practices in a tertiary care hospital in the United Arab Emirates. Ibnosina Journal of Medicine & Biomedical Sciences, 4(3), 84-89.

Myers, J. A., Psirides, A., Hathaway, K., & Larsen, P. D. (2012). Air transport by the Wellington Flight Service: A descriptive analysis of interhospital transfers over a 5-year period in the Wellington region of New Zealand. New Zealand Medical Journal, 125(1351). Retrieved from http://www.nzma.org.nz/journal

Sykes, A. J., Larsen, P. D., Griffiths, R. F., & Aldington, S. (2012). A study of airline pilot morbidity. Aviation, Space, & Environmental Medicine, 83(10), 1001-1005. doi: 10.3357/asem.3380.2012

Wilson, D., Harding, S. A., Melton, I., Lever, N. A., Stiles, M. K., Boddington, D., Heald, S., & Larsen, P. D. (2012). Geographic, ethnic and socioeconomic factors influencing access to implantable cardioverter defibrillators (ICDs) in New Zealand. Heart, Lung & Circulation, 21(9), 576-581. doi: 10.1016/j.hlc.2012.04.012

Wirawan, I. M. A., Larsen, P. D., Aldington, S., Griffiths, R. F., & Ellis, C. J. (2012). Cardiovascular risk score and cardiovascular events among airline pilots: A case-control study. Aviation, Space, & Environmental Medicine, 83(5), 465-471. doi: 10.3357/ASEM.3222.2012

Elder, D. E., Campbell, A. J., Larsen, P. D., & Galletly, D. (2011). Respiratory variability in preterm and term infants: Effect of sleep state, position and age. Respiratory Physiology & Neurobiology, 175(2), 234-238. doi: 10.1016/j.resp.2010.11.011

Burgess, S. N., Harding, S. A., Melton, I. C., Lever, N. A., Swain, A. H., Shi, B., & Larsen, P. D. (2011). An unmet need for implantable cardioverter-defibrillators in New Zealand. Europace, 13(9), 1299-1303. doi: 10.1093/europace/eur113

Swain, A. H., Barry, T., Hoyle, S. R., Haywood, G., Cameron, H., & Larsen, P. D. (2011). Outcomes from out-of-hospital cardiac arrest in the Wellington region of New Zealand: Does use of the Fire Service make a difference? New Zealand Medical Journal, 124(1344). Retrieved from http://journal.nzma.org.nz/journal/124-1344/4913/content.pdf

Mahony, P. H., Myers, J. A., Larsen, P. D., Powell, D. M., & Griffiths, R. F. (2011). Symptom-based categorization of in-flight passenger medical incidents. Aviation, Space, & Environmental Medicine, 82(12), 1131-1137. doi: 10.3357/ASEM.3099.2011

Robinson, S., Swain, A. H., Hoyle, S. R., & Larsen, P. D. (2010). Survival from out-of-hospital cardiac arrest in New Zealand following the 2005 resuscitation guideline changes. Resuscitation, 81(12), 1648-1651. doi: 10.1016/j.resuscitation.2010.07.009

Elder, D. E., Larsen, P. D., Galletly, D. C., & Campbell, A. J. (2010). Cardioventilatory coupling in preterm and term infants: Effect of position and sleep state. Respiratory Physiology & Neurobiology, 174(1-2), 128-134. doi: 10.1016/j.resp.2010.05.012

Marsland, C., Larsen, P., Segal, R., Hunter, S., Morris, J., Mezzavia, P., … Lim, W. (2010). Proficient manipulation of fibreoptic bronchoscope to carina by novices on first clinical attempt after specialized bench practice. British Journal of Anaesthesia, 104(3), 375-381. doi: 10.1093/bja/aeq005

Sin, P. Y. W., Webber, M. R., Galletly, D. C., Ainslie, P. N., Brown, S. J., Willie, C. K., Sasse, A., Larsen, P. D., & Tzeng, Y.-C. (2010). Interactions between heart rate variability and pulmonary gas exchange efficiency in humans. Experimental Physiology, 95(7), 788-797. doi: 10.1113/expphysiol.2010.052910

Larsen, P. D., De Silva, P., Harding, S. A., Woodcock, E., & Lever, N. A. (2010). Use of implantable cardioverter defibrillators in the New Zealand context from 2000 to 2007. New Zealand Medical Journal, 123(1309). Retrieved from http://journal.nzma.org.nz/journal/123-1309/3977/content.pdf

Larsen, P. D., Tzeng, Y. C., Sin, P. Y. W., & Galletly, D. C. (2010). Respiratory sinus arrhythmia in conscious humans during spontaneous respiration. Respiratory Physiology & Neurobiology, 174(1-3), 111-118. doi: 10.1016/j.resp.2010.04.021

Panfilov, I., Lever, N. A., Smaill, B. H., & Larsen, P. D. (2009). Ventricular fibrillation frequency from implanted cardioverter defibrillator devices. Europace, 11(8), 1052-1056. doi: 10.1093/europace/eup159

Hermiz, S., Larsen, P., Galletly, D. C., & Harding, S. A. (2009). Peri-operative management of anti-platelet agents. ANZ Journal of Surgery, 79(7-8), 521-525. doi: 10.1111/j.1445-2197.2009.04981.x

Lever, N. A., Larsen, P. D., Dawes, M., Wong, A., & Harding, S. A. (2009). Are our medical graduates in New Zealand safe and accurate in ECG interpretation? New Zealand Medical Journal, 122(1292). Retrieved from http://journal.nzma.org.nz/journal/122-1292/3536/content.pdf

McHale, B., Harding, S. A., Larsen, P. D., & Lever, N. A. (2009). A national survey of clinician's knowledge of and attitudes towards implantable cardioverter defibrillators. Europace, 11(10), 1313-1316. doi: 10.1093/europace/eup236

Mahony, P. H., Griffiths, R. F., Larsen, P., & Powell, D. (2008). Retention of knowledge and skills in first aid and resuscitation by airline cabin crew. Resuscitation, 76, 413-418. doi: 10.1016/j.resuscitation.2007.08.017

Elder, D. E., Larsen, P., & Zuccollo, J. M. (2008). Failure of apnea monitoring during bed-sharing. Forensic Science, Medicine, & Pathology, 4(3), 167-169. doi: 10.1007/s12024-008-9026-z

Tzeng, Y. C., Larsen, P. D., & Galletly, D. C. (2007). Effects of hypercapnia and hypoxemia on respiratory sinus arrhythmia in conscious humans during spontaneous respiration. American Journal of Physiology: Heart & Circulatory Physiology, 292, H2397-H2407. doi: 10.1152/ajpheart.00817.2006

Tzeng, Y. C., Larsen, P. D., & Galletly, D. C. (2007). Mechanism of cardioventilatory coupling: Insights from cardiac pacing, vagotomy, and sinoaortic denervation in the anesthetized rat. American Journal of Physiology: Heart & Circulatory Physiology, 292, H1967-H1977. doi: 10.1152/ajpheart.01049.2006

Parnell, M. M., & Larsen, P. D. (2007). Poor quality teaching in lay person CPR courses. Resuscitation, 73, 271-278.

Lever, N. A., Newall, E. G., & Larsen, P. D. (2007). Differences in the characteristics of induced and spontaneous episodes of ventricular fibrillation. Europace, 9, 1054-1058.

Newall, E. G., Lever, N. A., Prasad, S., Hornabrook, C., & Larsen, P. D. (2007). Psychological implications of ICD implantation in a New Zealand population. Europace, 9, 20-24.

Parnell, M. M., Pearson, J., Galletly, D. C., & Larsen, P. D. (2006). Knowledge of and attitudes towards resuscitation in New Zealand high-school students. Emergency Medicine Journal, 23, 899-902.

Tanner, H., Larsen, P., Lever, N., & Galletly, D. (2006). Early recognition and early access for acute coronary syndromes in New Zealand: Key links in the chain of survival. New Zealand Medical Journal, 119(1232). Retrieved from http://journal.nzma.org.nz/journal/119-1232/1927/content.pdf

O'Keeffe, K. M., Galletly, D. C., Miller, J. H., & Larsen, P. D. (2005). Quantal breathing frequency variation in halothane anaethetised neonatal rats. Respiratory Physiology & Neurobiology, 146(2-3), 147-153.

Tzeng, Y.-C., Galletly, D. C., & Larsen, P. D. (2005). Paradoxical respiratory sinus arrhythmia in the anesthetized rat. Autonomic Neuroscience, 118(1-2), 25-31.

Williamson, L. J., Larsen, P. D., Tzeng, Y.-C., & Galletly, D. C. (2005). Effect of automatic external defibrillator audio prompts on cardiopulmonary resuscitation performance. Emergency Medicine Journal, 22(2), 140-143.

Weller, J. M., Robinson, B. J., Jolly, B., Watterson, L. M., Joseph, M., Bajenov, S., … Larsen, P. D. (2005). Psychometric characteristics of simulation-based assessment in anaesthesia and accuracy of self-assessed scores. Anaesthesia, 60(3), 245-250.

Galletly, D., Larsen, P., Lever, N., Aickin, R., & Smith, W. (2004). Energy settings for mono- and biphasic defibrillation: Guideline of the New Zealand Resuscitation Council [Review article]. New Zealand Medical Journal, 117(1193). Retrieved from http://journal.nzma.org.nz/journal/117-1193/875/content.pdf

Martin, K. M., Larsen, P. D., Segal, R., & Marsland, C. P. (2004). Effective nonanatomical endoscopy training produces clinical airway endoscopy proficiency. Anesthesia & Analgesia, 99(3), 938-944.

Larsen, P. D., Elder, D. E., Tzeng, Y.-C., Campbell, A., & Galletly, D. C. (2004). Fractal characteristics of breath to breath timing in sleeping infants. Respiratory Physiology & Neurobiology, 139(3), 263-270.

McGuinness, M., Hong, Y., Galletly, D., & Larsen, P. (2004). Arnold tongues in human cardiorespiratory systems. Chaos, 14(1), 1-13.

Larsen, P., Pearson, J., & Galletly, D. (2004). Knowledge and attitudes towards cardiopulmonary resuscitation in the community. New Zealand Medical Journal, 117(1193). Retrieved from http://journal.nzma.org.nz/journal/117-1193/870/content.pdf

Weller, J., Robinson, B., Larsen, P., & Caldwell, C. (2004). Simulation-based training to improve acute care skills in medical undergraduates. New Zealand Medical Journal, 117(1204). Retrieved from http://journal.nzma.org.nz/journal/117-1204/1119/content.pdf

Larsen, P. D., Tzeng, Y.-C., & Galletly, D. C. (2003). Inspiratory coupling to cardiac activity and to somatic afferent nerve stimulation in the anaesthetised rat. Autonomic Neuroscience, 108, 45-49.

Ryan, A. D., Larsen, P. D., & Galletly, D. C. (2003). Comparison of heart rate variability in supine, and left and right lateral positions. Anaesthesia, 58, 432-436.

Lafferty, C., Larsen, P., & Galletly, D. (2003). Resuscitation teaching in New Zealand schools. New Zealand Medical Journal, 116(1181). Retrieved from http://journal.nzma.org.nz/journal/116-1181/582/content.pdf

Tzeng, Y.-C., Larsen, P. D., & Galletly, D. C. (2003). Cardioventilatory coupling in resting human subjects. Experimental Physiology, 88.6, 775-782.

Larsen, P. D., Tzeng, Y.-C., & Galletly, D. C. (2003). Quantal ventilatory variability during spontaneous breathing anaesthesia. British Journal of Anaesthesia, 91(2), 184-189.

Eames, P., Larsen, P. D., & Galletly, D. C. (2003). Comparison of ease of use of three automated external defibrillators by untrained lay people. Resuscitation, 58, 25-30.

Larsen, P. D., Perrin, K., & Galletly, D. C. (2002). Patterns of external chest compression. Resuscitation, 53(3), 281-287.

Lewis, C. D., Gebber, G. L., Larsen, P., & Barman, S. M. (2001). Long term correlations in the spike trains of medullary sympathetic neurons. Journal of Neurophysiology, 85, 1614-1622.

Larsen, P., & Galletly, D. C. (2001). Cardioventilatory coupling in heart rate variability: The value of standard analytical techniques. British Journal of Anaesthesia, 87, 819-826.

Galletly, D. C., & Larsen, P. (2001). Cardioventilatory coupling in heart rate variability: Methods for qualitative and quantitative determination. British Journal of Anaesthesia, 87, 827-833.

Larsen, P., Zhong, S., Gebber, G. L., & Barman, S. M. (2001). Sympathetic nerve and cardiovascular responses to chemical activation of the midbrain defense region. American Journal of Physiology: Regulatory, Integrative & Comparative Physiology, 280, 1704-1712.

Galletly, D. C., & Larsen, P. (2001). Inspiratory timing during anaesthesia: A model of cardioventilatory coupling. British Journal of Anaesthesia, 86(6), 777-778.

Larsen, P., Zhong, S., Gebber, G. L., & Barman, S. M. (2000). Differential pattern in spinal sympathetic outflow in response to stimulation of the caudal medullary raphe. American Journal of Physiology: Regulatory, Integrative & Comparative Physiology, 279, R210-R221.

Larsen, P., Zhong, S., Lewis, C. D., Gebber, G. L., & Barman, S. M. (2000). Coupling of arterial pulse and 10-Hz rhythm in sympathetic nerve discharge. Brain Research, 883, 143-147.

Larsen, P., Lewis, C. D., Gebber, G. L., & Zhong, S. (2000). Partial spectral analysis of cardiac-related rhythm in sympathetic nerve discharge. Journal of Neurophysiology, 84, 1168-1179.

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