Accessibility Skip to Global Navigation Skip to Local Navigation Skip to Content Skip to Search Skip to Site Map Menu

Otago Medical School staff profiles

Dr Rachel Purcell

PositionResearch Fellow
DepartmentDepartment of Surgery (UOC)
QualificationsBSc(Hons)(Cork) MSc(Hons)(PIC) PhD(Otago)
Research summaryBowel cancer

Research

Rachel is a Research Fellow with the Department of Surgery. She has a background in molecular biology and cancer genetics. Her research is centred on the molecular mechanisms of pathogenic bacteria in colorectal carcinogenesis. Rachel's current research projects include investigating the effect of the gut microbiome on radiotherapy response in rectal cancer, microbiome-based markers of diverticular disease and molecular classification of colorectal cancer.

Publications

Stevens, A. J., Purcell, R. V., Darling, K. A., Eggleston, M. J. F., Kennedy, M. A., & Rucklidge, J. J. (2019). Human gut microbiome changes during a 10 week randomised control trial for micronutrient supplementation in children with attention deficit hyperactivity disorder. Scientific Reports, 9, 10128. doi: 10.1038/s41598-019-46146-3

Purcell, R. V., Kaakoush, N. O., Mitchell, H. M., Pearson, J. F., & Keenan, J. I. (2018). Gastrointestinal pathobionts in pediatric Crohn's disease patients. International Journal of Microbiology, 2018, 9203908. doi: 10.1155/2018/9203908

Purcell, R. V., Visnovska, M., Biggs, P. J., Schmeier, S., & Frizelle, F. A. (2017). Distinct gut microbiome patterns associate with consensus molecular subtypes of colorectal cancer. Scientific Reports, 7, 11590. doi: 10.1038/s41598-017-11237-6

Purcell, R. V., Pearson, J., Aitchison, A., Dixon, L., Frizelle, F. A., & Keenan, J. I. (2017). Colonization with enterotoxigenic Bacteroides fragilis is associated with early-stage colorectal neoplasia. PLoS ONE, 12(2), e0171602. doi: 10.1371/journal.pone.0171602

Purcell, R. V., Pearson, J., Frizelle, F. A., & Keenan, J. I. (2016). Comparison of standard, quantitative and digital PCR in the detection of enterotoxigenic Bacteroides fragilis. Scientific Reports, 6, 34554. doi: 10.1038/srep34554

Journal - Research Article

Stevens, A. J., Purcell, R. V., Darling, K. A., Eggleston, M. J. F., Kennedy, M. A., & Rucklidge, J. J. (2019). Human gut microbiome changes during a 10 week randomised control trial for micronutrient supplementation in children with attention deficit hyperactivity disorder. Scientific Reports, 9, 10128. doi: 10.1038/s41598-019-46146-3

Purcell, R. V., Kaakoush, N. O., Mitchell, H. M., Pearson, J. F., & Keenan, J. I. (2018). Gastrointestinal pathobionts in pediatric Crohn's disease patients. International Journal of Microbiology, 2018, 9203908. doi: 10.1155/2018/9203908

Purcell, R. V., Visnovska, M., Biggs, P. J., Schmeier, S., & Frizelle, F. A. (2017). Distinct gut microbiome patterns associate with consensus molecular subtypes of colorectal cancer. Scientific Reports, 7, 11590. doi: 10.1038/s41598-017-11237-6

Purcell, R. V., Pearson, J., Aitchison, A., Dixon, L., Frizelle, F. A., & Keenan, J. I. (2017). Colonization with enterotoxigenic Bacteroides fragilis is associated with early-stage colorectal neoplasia. PLoS ONE, 12(2), e0171602. doi: 10.1371/journal.pone.0171602

Purcell, R. V., Pearson, J., Frizelle, F. A., & Keenan, J. I. (2016). Comparison of standard, quantitative and digital PCR in the detection of enterotoxigenic Bacteroides fragilis. Scientific Reports, 6, 34554. doi: 10.1038/srep34554

Keenan, J. I., Aitchison, A., Purcell, R. V., Greenlees, R., Pearson, J. F., & Frizelle, F. A. (2016). Screening for enterotoxigenic Bacteroides fragilis in stool samples. Anaerobe, 40, 50-53. doi: 10.1016/j.anaerobe.2016.05.004

Chatterjee, A., Leichter, A. L., Fan, V., Tsai, P., Purcell, R. V., Sullivan, M. J., & Eccles, M. R. (2015). A cross comparison of technologies for the detection of microRNAs in clinical FFPE samples of hepatoblastoma patients. Scientific Reports, 5, 10438. doi: 10.1038/srep10438

Leichter, A. L., Purcell, R. V., Sullivan, M. J., Eccles, M. R., & Chatterjee, A. (2015). Multi-platform microRNA profiling of hepatoblastoma patients using formalin fixed paraffin embedded archival samples. GigaScience, 4, 54. doi: 10.1186/s13742-015-0099-9

Purcell, R., Childs, M., Maibach, R., Miles, C., Turner, C., Zimmermann, A., … Sullivan, M. (2012). Potential biomarkers for hepatoblastoma: Results from the SIOPEL-3 study. European Journal of Cancer, 48(12), 1853-1859. doi: 10.1016/j.ejca.2011.10.019

Purcell, R., Childs, M., Maibach, R., Miles, C., Turner, C., Zimmermann, A., & Sullivan, M. (2011). HGF/c-Met related activation of β-catenin in hepatoblastoma. Journal of Experimental & Clinical Cancer Research, 30, 96. doi: 10.1186/1756-9966-30-96

More publications...