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Otago Medical School staff profiles

Dr Mickey Fan

PositionPostdoctoral Fellow
DepartmentDepartment of Surgery and Anaesthesia (UOW)
Research summaryCerebral blood flow regulation; stroke; respiratory physiology

Research

I am a New Zealand Heart Foundation Research Fellow currently working with A/P Shieak Tzeng. My current research interests are stroke prevention with dietary supplementation, altitude exposure, training on weight loss, cerebral blood flow regulation, neuroprotection, high altitude physiology, respiratory control and altitude training. After obtaining my Bachelors in Physiology at University of Otago in Dunedin, I continued both my Postgraduate diploma and Masters in Physiology at University of Otago. My theses focused on the effect of passive heat stress and extreme high altitude on the regulation of cerebral blood flow. Following my Masters studies, I moved to Switzerland where I obtained a PhD in Neuroscience from the Lemanic Doctoral School of Neuroscience. During my time at the University of Geneva and later in Lausanne, I worked on the regulation of cerebral blood flow at high altitude and during exercise

Publications

Fan, J.-L., Cotter, J. D., Lucas, R. A. I., Thomas, K., Wilson, L., & Ainslie, P. N. (2008). Human cardiorespiratory and cerebrovascular function during severe passive hyperthermia: Effects of mild hypohydration. Journal of Applied Physiology, 105(2), 433-445.

Fan, J.-L., Subudhi, A. W., Evero, O., Bourdillon, N., Kayser, B., Lovering, A. T., & Roach, R. C. (2014). AltitudeOmics: Enhanced cerebrovascular reactivity and ventilatory response to CO2 with high-altitude acclimatization and reexposure. Journal of Applied Physiology, 116, 911-918. doi: 10.1152/japplphysiol.00704.2013

Fan, J.-L., Subudhi, A. W., Duffin, J., Lovering, A. T., Roach, R. C., & Kayser, B. (2016). AltitudeOmics: Resetting of cerebrovascular CO2 reactivity following acclimatization to high altitude. Frontiers in Physiology, 6, 394. doi: 10.3389/fphys.2015.00394

Fan, J.-L., Burgess, K. R., Basnyat, R., Thomas, K. N., Peebles, K. C., Lucas, S. J., Lucas, R. A., Donnelly, J., Cotter, J. D., & Ainslie, P. N. (2010). Influence of high altitude on cerebrovascular responsiveness to CO2. Journal of Physiology, 588(3), 539-549. doi: 10.1113/jphysiol.2009.184051

Fan, J.-L., Burgess, K. R., Thomas, K. N., Lucas, S. J. E., Cotter, J. D., Kayser, B., Peebles, K. C., & Ainslie, P. N. (2012). Effects of acetazolamide on cerebrovascular function and breathing stability at 5050m. Journal of Physiology, 590(5), 1213-1225. doi: 10.1113/jphysiol.2011.219923

Journal - Research Article

Fan, J.-L., Subudhi, A. W., Duffin, J., Lovering, A. T., Roach, R. C., & Kayser, B. (2016). AltitudeOmics: Resetting of cerebrovascular CO2 reactivity following acclimatization to high altitude. Frontiers in Physiology, 6, 394. doi: 10.3389/fphys.2015.00394

Fan, J.-L., Subudhi, A. W., Evero, O., Bourdillon, N., Kayser, B., Lovering, A. T., & Roach, R. C. (2014). AltitudeOmics: Enhanced cerebrovascular reactivity and ventilatory response to CO2 with high-altitude acclimatization and reexposure. Journal of Applied Physiology, 116, 911-918. doi: 10.1152/japplphysiol.00704.2013

Subudhi, A. W., Bourdillon, N., Bucher, J., Davis, C., Elliott, J. E., Eutermoster, M., … Fan, J.-L., … Roach, R. C. (2014). AltitudeOmics: The integrative physiology of human acclimatization to hypobaric hypoxia and its retention upon reascent. PLoS ONE, 9(3), e92191. doi: 10.1371/journal.pone.0092191

Fan, J.-L., Burgess, K. R., Thomas, K. N., Lucas, S. J. E., Cotter, J. D., Kayser, B., Peebles, K. C., & Ainslie, P. N. (2012). Effects of acetazolamide on cerebrovascular function and breathing stability at 5050m. Journal of Physiology, 590(5), 1213-1225. doi: 10.1113/jphysiol.2011.219923

Fan, J.-L., Burgess, K. R., Basnyat, R., Thomas, K. N., Peebles, K. C., Lucas, S. J., Lucas, R. A., Donnelly, J., Cotter, J. D., & Ainslie, P. N. (2010). Influence of high altitude on cerebrovascular responsiveness to CO2. Journal of Physiology, 588(3), 539-549. doi: 10.1113/jphysiol.2009.184051

Fan, J.-L., Cotter, J. D., Lucas, R. A. I., Thomas, K., Wilson, L., & Ainslie, P. N. (2008). Human cardiorespiratory and cerebrovascular function during severe passive hyperthermia: Effects of mild hypohydration. Journal of Applied Physiology, 105(2), 433-445.

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