Accessibility Skip to Global Navigation Skip to Local Navigation Skip to Content Skip to Search Skip to Site Map Menu

Otago Medical School staff profiles

Zin Khant Aung

PositionAssistant Research Fellow
DepartmentDepartment of Anatomy
QualificationsBSc PGDipSci MSc
Research summaryNeuroendocrine regulation of body weight and glucose homeostasis

Research

Our research group (Grattan Group) is interested in the neuroendocrine regulation of body weight and glucose homeostasis. Specific projects include hypothalamic signal transduction pathways activated in response to metabolic signals, mechanisms of "leptin resistance" contributing to the development of obesity, and pregnancy-induced adaptation in metabolic regulation.

Publications

Barad, Z., Khant Aung, Z., Grattan, D. R., Ladyman, S. R., & Brown, R. S. E. (2020). Impaired prolactin transport into the brain and functional responses to prolactin in aged male mice. Journal of Neuroendocrinology, 32, e12889. doi: 10.1111/jne.12889

Khant Aung, Z., Grattan, D. R., & Ladyman, S. R. (2020). Pregnancy-induced adaptation of central sensitivity to leptin and insulin. Molecular & Cellular Endocrinology, 516, 110933. doi: 10.1016/j.mce.2020.110933

Gustafson, P., Ladyman, S. R., McFadden, S., Larsen, C., Khant Aung, Z., Brown, R. S. E., Bunn, S., & Grattan, D. R. (2020). Prolactin receptor-mediated activation of pSTAT5 in the pregnant mouse brain. Journal of Neuroendocrinology. Advance online publication. doi: 10.1111/jne.12901

Brown, R. S. E., Khant Aung, Z., Phillipps, H. R., Barad, Z., Lein, H.-J., Boehm, U., Szawka, R. E., & Grattan, D. R. (2019). Acute suppression of LH secretion by prolactin in female mice is mediated by kisspeptin neurons in the arcuate nucleus. Endocrinology, 160(5), 1323-1332. doi: 10.1210/en.2019-00038

Augustine, R. A., Knowles, P. J., Khant Aung, Z., Grattan, D. R., & Ladyman, S. R. (2019). Impaired hypothalamic leptin sensitivity in pseudopregnant rats treated with chronic prolactin to mimic pregnancy. Journal of Neuroendocrinology, 31, e12702. doi: 10.1111/jne.12702

Journal - Research Article

Barad, Z., Khant Aung, Z., Grattan, D. R., Ladyman, S. R., & Brown, R. S. E. (2020). Impaired prolactin transport into the brain and functional responses to prolactin in aged male mice. Journal of Neuroendocrinology, 32, e12889. doi: 10.1111/jne.12889

Gustafson, P., Ladyman, S. R., McFadden, S., Larsen, C., Khant Aung, Z., Brown, R. S. E., Bunn, S., & Grattan, D. R. (2020). Prolactin receptor-mediated activation of pSTAT5 in the pregnant mouse brain. Journal of Neuroendocrinology. Advance online publication. doi: 10.1111/jne.12901

Khant Aung, Z., Grattan, D. R., & Ladyman, S. R. (2020). Pregnancy-induced adaptation of central sensitivity to leptin and insulin. Molecular & Cellular Endocrinology, 516, 110933. doi: 10.1016/j.mce.2020.110933

Brown, R. S. E., Khant Aung, Z., Phillipps, H. R., Barad, Z., Lein, H.-J., Boehm, U., Szawka, R. E., & Grattan, D. R. (2019). Acute suppression of LH secretion by prolactin in female mice is mediated by kisspeptin neurons in the arcuate nucleus. Endocrinology, 160(5), 1323-1332. doi: 10.1210/en.2019-00038

Augustine, R. A., Knowles, P. J., Khant Aung, Z., Grattan, D. R., & Ladyman, S. R. (2019). Impaired hypothalamic leptin sensitivity in pseudopregnant rats treated with chronic prolactin to mimic pregnancy. Journal of Neuroendocrinology, 31, e12702. doi: 10.1111/jne.12702

Ladyman, S. R., Khant Aung, Z., & Grattan, D. R. (2018). Impact of pregnancy and lactation on the long-term regulation of energy balance in female mice. Endocrinology, 159(6), 2324-2336. doi: 10.1210/en.2018-00057

McEwen, H. J. L., Cognard, E., Ladyman, S. R., Khant-Aung, Z., Tups, A., Shepherd, P. R., & Grattan, D. R. (2018). Feeding and GLP-1 receptor activation stabilize beta-catenin in specific hypothalamic nuclei in male rats. Journal of Neuroendocrinology, 30(6), e12607, 1-10. doi: 10.1111/jne.12607

Ladyman, S. R., MacLeod, M. A., Khant Aung, Z., Knowles, P., Phillipps, H. R., Brown, R. S. E., & Grattan, D. R. (2017). Prolactin receptors in Rip-cre cells, but not in AgRP neurons, are involved in energy homeostasis. Journal of Neuroendocrinology, 29(10), e12474. doi: 10.1111/jne.12474

More publications...