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Otago Medical School staff profiles

Dr Hannah Hampton

PositionPostdoctoral Fellow
DepartmentDepartment of Microbiology and Immunology

Research

Hannah is working in Professor Peter Fineran’s laboratory.

Publications

Beck, I. N., Usher, B., Hampton, H. G., Fineran, P. C., & Blower, T. R. (2020). Antitoxin autoregulation of M. tuberculosis toxin-antitoxin expression through negative cooperativity arising from multiple inverted repeat sequences. Biochemical Journal, 477, 2401-2419. doi: 10.1042/bcj20200368

Hampton, H. G., Smith, L. M., Ferguson, S., Meaden, S., Jackson, S. A., & Fineran, P. C. (2020). Functional genomics reveals the toxin-antitoxin repertoire and AbiE activity in Serratia. Microbial Genomics. Advance online publication. doi: 10.1099/mgen.0.000458

Hampton, H. G., Watson, B. N. J., & Fineran, P. C. (2020). The arms race between bacteria and their phage foes. Nature, 577(7790), 327-336. doi: 10.1038/s41586-019-1894-8

Hampton, H. G., Patterson, A. G., Chang, J. T., Taylor, C., & Fineran, P. C. (2019). GalK limits type I-F CRISPR-Cas expression in a CRP-dependent manner. FEMS Microbiology Letters, 366, fnz137. doi: 10.1093/femsle/fnz137

Hampton, H. G., Jackson, S. A., Fagerlund, R. D., Vogel, A. I. M., Dy, R. L., Blower, T. R., & Fineran, P. C. (2018). AbiEi binds cooperatively to the Type IV abiE toxin-antitoxin operator via a positively-charged surface and causes DNA bending and negative autoregulation. Journal of Molecular Biology, 430(8), 1141-1156. doi: 10.1016/j.jmb.2018.02.022

Journal - Research Article

Beck, I. N., Usher, B., Hampton, H. G., Fineran, P. C., & Blower, T. R. (2020). Antitoxin autoregulation of M. tuberculosis toxin-antitoxin expression through negative cooperativity arising from multiple inverted repeat sequences. Biochemical Journal, 477, 2401-2419. doi: 10.1042/bcj20200368

Hampton, H. G., Smith, L. M., Ferguson, S., Meaden, S., Jackson, S. A., & Fineran, P. C. (2020). Functional genomics reveals the toxin-antitoxin repertoire and AbiE activity in Serratia. Microbial Genomics. Advance online publication. doi: 10.1099/mgen.0.000458

Hampton, H. G., Patterson, A. G., Chang, J. T., Taylor, C., & Fineran, P. C. (2019). GalK limits type I-F CRISPR-Cas expression in a CRP-dependent manner. FEMS Microbiology Letters, 366, fnz137. doi: 10.1093/femsle/fnz137

Hampton, H. G., Jackson, S. A., Fagerlund, R. D., Vogel, A. I. M., Dy, R. L., Blower, T. R., & Fineran, P. C. (2018). AbiEi binds cooperatively to the Type IV abiE toxin-antitoxin operator via a positively-charged surface and causes DNA bending and negative autoregulation. Journal of Molecular Biology, 430(8), 1141-1156. doi: 10.1016/j.jmb.2018.02.022

Hampton, H. G., McNeil, M. B., Paterson, T. J., Ney, B., Williamson, N. R., Easingwood, R. A., Bostina, M., … Fineran, P. C. (2016). CRISPR-Cas gene-editing reveals RsmA and RsmC act through FlhDC to repress the SdhE flavinylation factor and control motility and prodigiosin production in Serratia. Microbiology, 162(6), 1047-1058. doi: 10.1099/mic.0.000283

McNeil, M. B., Hampton, H. G., Hards, K. J., Watson, B. N. J., Cook, G. M., & Fineran, P. C. (2014). The succinate dehydrogenase assembly factor, SdhE, is required for the flavinylation and activation of fumarate reductase in bacteria. FEBS Letters, 588(3), 414-421. doi: 10.1016/j.febslet.2013.12.019

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Journal - Research Other

Hampton, H. G., Watson, B. N. J., & Fineran, P. C. (2020). The arms race between bacteria and their phage foes. Nature, 577(7790), 327-336. doi: 10.1038/s41586-019-1894-8

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