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Otago Medical School staff profiles

Dr Murray Cadzow

PositionPostdoctoral Fellow
DepartmentDepartment of Biochemistry

Publications

Narang, R. K., Gamble, G., Phipps-Green, A. J., Topless, R., Cadzow, M., Stamp, L. K., Merriman, T. R., & Dalbeth, N. (2020). Do serum urate-associated genetic variants influence gout risk in people on diuretics? Analysis of the UK Biobank. Journal of Rheumatology. Advance online publication.

Boocock, J., Leask, M., Okada, Y., Asian Genetic Epidemiology Network (AGEN) Consortium, Matsuo, H., Shi, Y., … Cadzow, M., Gosling, A. L., Flynn, T. J., Horsfield, J. A., … Merriman, T. R. (2020). Genomic dissection of 43 serum urate-associated loci provides multiple insights into molecular mechanisms of urate control. Human Molecular Genetics. Advance online publication. doi: 10.1093/hmg/ddaa013

Winbo, A., Earle, N., Marcondes, L., Crawford, J., Prosser, D. O., Love, D. R., Merriman, T. R., Cadzow, M., … Skinner, J. R. (2020). Genetic testing in Polynesian Long QT Syndrome probands reveals a lower diagnostic yield and an increased prevalence of rare variants. Heart Rhythm. Advance online publication. doi: 10.1016/j.hrthm.2020.03.015

Tai, V., Narang, R. K., Gamble, G., Cadzow, M., Stamp, L. K., Merriman, T. R., & Dalbeth, N. (2020). Do serum urate-associated genetic variants differentially contribute to gout risk according to body mass index? Analysis of the UK Biobank. Arthritis & Rheumatology. Advance online publication. doi: 10.1002/art.41219

Lacey, C. J., Doudney, K., Bridgman, P. G., George, P. M., Mulder, R. T., Zarifeh, J. J., Kimber, B., Cadzow, M. J., Black, M. A., Merriman, T. R., … Pearson, J. F., Cameron, V. A., & Kennedy, M. A. (2018). Copy number variants implicate cardiac function and development pathways in earthquake-induced stress cardiomyopathy. Scientific Reports, 8, 7548. doi: 10.1038/s41598-018-25827-5

Chapter in Book - Research

Peters, B., Aidley, J., Cadzow, M., Twell, D., & Brownfield, L. (2017). Identification of cis-regulatory modules that function in the male germline of flowering plants. In A. Schmidt (Ed.), Plant germline development: Methods and protocols: Methods in molecular biology (Vol. 1669). (pp. 275-293). Springer. doi: 10.1007/978-1-4939-7286-9_22

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Journal - Research Article

Narang, R. K., Gamble, G., Phipps-Green, A. J., Topless, R., Cadzow, M., Stamp, L. K., Merriman, T. R., & Dalbeth, N. (2020). Do serum urate-associated genetic variants influence gout risk in people on diuretics? Analysis of the UK Biobank. Journal of Rheumatology. Advance online publication.

Tai, V., Narang, R. K., Gamble, G., Cadzow, M., Stamp, L. K., Merriman, T. R., & Dalbeth, N. (2020). Do serum urate-associated genetic variants differentially contribute to gout risk according to body mass index? Analysis of the UK Biobank. Arthritis & Rheumatology. Advance online publication. doi: 10.1002/art.41219

Winbo, A., Earle, N., Marcondes, L., Crawford, J., Prosser, D. O., Love, D. R., Merriman, T. R., Cadzow, M., … Skinner, J. R. (2020). Genetic testing in Polynesian Long QT Syndrome probands reveals a lower diagnostic yield and an increased prevalence of rare variants. Heart Rhythm. Advance online publication. doi: 10.1016/j.hrthm.2020.03.015

Boocock, J., Leask, M., Okada, Y., Asian Genetic Epidemiology Network (AGEN) Consortium, Matsuo, H., Shi, Y., … Cadzow, M., Gosling, A. L., Flynn, T. J., Horsfield, J. A., … Merriman, T. R. (2020). Genomic dissection of 43 serum urate-associated loci provides multiple insights into molecular mechanisms of urate control. Human Molecular Genetics. Advance online publication. doi: 10.1093/hmg/ddaa013

Lacey, C. J., Doudney, K., Bridgman, P. G., George, P. M., Mulder, R. T., Zarifeh, J. J., Kimber, B., Cadzow, M. J., Black, M. A., Merriman, T. R., … Pearson, J. F., Cameron, V. A., & Kennedy, M. A. (2018). Copy number variants implicate cardiac function and development pathways in earthquake-induced stress cardiomyopathy. Scientific Reports, 8, 7548. doi: 10.1038/s41598-018-25827-5

Tanner, C., Boocock, J., Stahl, E. A., Dobbyn, A., Mandal, A. K., Cadzow, M., Phipps-Green, A. J., Topless, R. K., … Stamp, L. K., … Merriman, T. R. (2017). Population specific resequencing associates the ATP binding cassette subfamily C member 4 (ABCC4) gene with gout in New Zealand Māori and Pacific men. Arthritis & Rheumatology, 69(7), 1461-1469. doi: 10.1002/art.40110

Cadzow, M., Merriman, T. R., & Dalbeth, N. (2017). Performance of gout definitions for genetic epidemiological studies: Analysis of UK Biobank. Arthritis Research & Therapy, 19(1), 181. doi: 10.1186/s13075-017-1390-1

Oliver, V. F., van Bysterveldt, K. A., Cadzow, M., Steger, B., Romano, V., Markie, D., … Vincent, A. L. (2016). A COL17A1 splice-altering mutation is prevalent in inherited recurrent corneal erosions. Ophthalmology, 123(4), 709-722. doi: 10.1016/j.ophtha.2015.12.008

Cadzow, M., Merriman, T. R., Boocock, J., Dalbeth, N., Stamp, L. K., Black, M. A., … Wilcox, P. L. (2016). Lack of direct evidence for natural selection at the candidate thrifty gene locus, PPARGC1A. BMC Medical Genetics, 17, 80. doi: 10.1186/s12881-016-0341-z

Topless, R. K., Flynn, T. J., Cadzow, M., Stamp, L. K., Dalbeth, N., Black, M. A., & Merriman, T. R. (2015). Association of SLC2A9 genotype with phenotypic variability of serum urate in pre-menopausal women. Frontiers in Genetics, 6, 313. doi: 10.3389/fgene.2015.00313

Flynn, T. J., Cadzow, M., Dalbeth, N., Jones, P. B., Stamp, L. K., Harré Hindmarsh, J., Todd, A. S., Walker, R. J., Topless, R., & Merriman, T. R. (2015). Positive association of tomato consumption with serum urate: Support for tomato consumption as an anecdotal trigger of gout flares. BMC Musculoskeletal Disorders, 16, 196. doi: 10.1186/s12891-015-0661-8

Dalbeth, N., Topless, R., Flynn, T., Cadzow, M., Bolland, M. J., & Merriman, T. R. (2015). Mendelian randomization analysis to examine for a causal effect of urate on bone mineral density. Journal of Bone & Mineral Research, 30(6), 985-991. doi: 10.1002/jbmr.2434

Batt, C., Phipps-Green, A. J., Black, M. A., Cadzow, M., Merriman, M. E., Topless, R., … Harrison, A., Highton, J., … Stamp, L., … Merriman, T. R. (2014). Sugar-sweetened beverage consumption: A risk factor for prevalent gout with SLC2A9 genotype-specific effects on serum urate and risk of gout. Annals of the Rheumatic Diseases, 73(12), 2101-2106. doi: 10.1136/annrheumdis-2013-203600

Dalbeth, N., House, M. E., Gamble, G. D., Pool, B., Horne, A., Purvis, L., … Merriman, M., Cadzow, M., Phipps-Green, A., & Merriman, T. R. (2014). Influence of the ABCG2 gout risk 141 K allele on urate metabolism during a fructose challenge. Arthritis Research & Therapy, 16, R34. doi: 10.1186/ar4463

Roberts, R. L., Wallace, M. C., Wright, D. F. B., Cadzow, M., Dalbeth, N., Jones, P. B., Stamp, L. K., Harrison, A. A., Black, M. A., & Merriman, T. R. (2014). Frequency of CYP2C9 polymorphisms in Polynesian people and potential relevance to management of gout with benzbromarone. Joint Bone Spine, 81(2), 160-163. doi: 10.1016/j.jbspin.2013.07.006

Vincent, A. L., Jordan, C. A., Cadzow, M. J., Merriman, T. R., & McGhee, C. N. (2014). Mutations in the zinc finger protein gene, Znf469, contribute to the pathogenesis of keratoconus. Investigative Ophthalmology & Visual Science, 55(9), 5629-5635. doi: 10.1167/iovs.14-14532

Cadzow, M., Boocock, J., Nguyen, H. T., Wilcox, P., Merriman, T. R., & Black, M. A. (2014). A bioinformatics workflow for detecting signatures of selection in genomic data. Frontiers in Genetics, 5, 293. doi: 10.3389/fgene.2014.00293

Dalbeth, N., House, M. E., Gamble, G. D., Horne, A., Pool, B., Purvis, L., … Merriman, M., Cadzow, M., Phipps-Green, A., & Merriman, T. R. (2013). Population-specific influence of SLC2A9 genotype on the acute hyperuricaemic response to a fructose load. Annals of the Rheumatic Diseases, 72(11), 1868-1873. doi: 10.1136/annrheumdis-2012-202732

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Journal - Research Other

Dalbeth, N., House, M. E., Gamble, G. D., Home, A., Purvis, L., Stewart, A., Merriman, M., Cadzow, M., Phipps-Green, A., & Merriman, T. (2014). Population-specific effects of SLC17A1 genotype on serum urate concentrations and renal excretion of uric acid during a fructose load. Annals of the Rheumatic Diseases. doi: 10.1136/annrheumdis-2013-203767

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