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Otago Medical School staff profiles

Associate Professor Liz Dennett

PositionAssociate Professor
DepartmentDepartment of Surgery and Anaesthesia (Wellington)
QualificationsBMedSci MB ChB
Research summaryColorectal cancer

Research

My research focuses on biomarkers in predicting prognosis and response to adjuvant therapies in colorectal cancer and quality and safety research within the health system. Specifically I am interested in:
  • Diagnostic and prognostic biomarkers of disease
  • Colorectal cancer
  • Ethnic disparities in disease outcomes
  • Clinical epidemiology
  • System improvements
  • Healthcare economics

Publications

de Burlet, K. J., Lam, A. B. M., Harper, S. J., Larsen, P. D., & Dennett, E. R. (2019). Can surgical registrars accurately identify the urgent from the non-urgent patient presenting with acute abdominal pain? European Surgical Research, 60(1-2), 24-30. doi: 10.1159/000496021

Gunawardene, A., Larsen, P., Shekouh, A., & Dennett, E. (2018). Pre-operative carcinoembryonic antigen predicts survival following colorectal cancer surgery with curative intent. ANZ Journal of Surgery. Advance online publication. doi: 10.1111/ans.14723

Tinawi, G., Gunawardene, A., Shekouh, A., Larsen, P. D., & Dennett, E. R. (2018). Neoadjuvant therapy in rectal cancer: How are we choosing? ANZ Journal of Surgery. Advance online publication. doi: 10.1111/ans.14935

de Burlet, K. J., MacKay, M., Larsen, P., & Dennett, E. R. (2018). Appropriateness of CT scans for patients with non-traumatic acute abdominal pain. British Journal of Radiology, 91(1088), 20180158. doi: 10.1259/bjr.20180158

de Burlet, K. J., Desmond, B., Harper, S. J., Larsen, P. D., & Dennett, E. R. (2018). Patients requiring an acute operation: Where are the delays in the process? ANZ Journal of Surgery. Advance online publication. doi: 10.1111/ans.14718

Chapter in Book - Research

Dennett, E. R., & Parry, B. R. (2000). The rationing of surgery: Clinical judgement vs priority setting: Are the methods appropriate and valid? In The global Challenge of Health Care Rationing. London: Open University Press.

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Journal - Research Article

de Burlet, K. J., Lam, A. B. M., Harper, S. J., Larsen, P. D., & Dennett, E. R. (2019). Can surgical registrars accurately identify the urgent from the non-urgent patient presenting with acute abdominal pain? European Surgical Research, 60(1-2), 24-30. doi: 10.1159/000496021

Gunawardene, A., Larsen, P., Shekouh, A., & Dennett, E. (2018). Pre-operative carcinoembryonic antigen predicts survival following colorectal cancer surgery with curative intent. ANZ Journal of Surgery. Advance online publication. doi: 10.1111/ans.14723

de Burlet, K. J., Desmond, B., Harper, S. J., Larsen, P. D., & Dennett, E. R. (2018). Patients requiring an acute operation: Where are the delays in the process? ANZ Journal of Surgery. Advance online publication. doi: 10.1111/ans.14718

de Burlet, K. J., MacKay, M., Larsen, P., & Dennett, E. R. (2018). Appropriateness of CT scans for patients with non-traumatic acute abdominal pain. British Journal of Radiology, 91(1088), 20180158. doi: 10.1259/bjr.20180158

Tinawi, G., Gunawardene, A., Shekouh, A., Larsen, P. D., & Dennett, E. R. (2018). Neoadjuvant therapy in rectal cancer: How are we choosing? ANZ Journal of Surgery. Advance online publication. doi: 10.1111/ans.14935

Gunawardene, A., Desmond, B., Shekouh, A., Larsen, P., & Dennett, E. (2018). Disease recurrence following surgery for colorectal cancer: Five-year follow-up. New Zealand Medical Journal, 131(1469), 51-58. Retrieved from https://www.nzma.org.nz/journal

de Burlet, K., Lam, A., Larsen, P., & Dennett, E. (2017). Acute abdominal pain: Changes in the way we assess it over a decade. New Zealand Medical Journal, 130(1463), 39-44. Retrieved from https://www.nzma.org.nz/journal

Keating, J. P., Manning, S., Dennett, E., & Studd, R. (2017). Excision of the seminal vesicles for locally advanced and recurrent rectal and sigmoid cancer. ANZ Journal of Surgery, 87(9), 688-691. doi: 10.1111/ans.13071

Sarfati, D., Gurney, J., Lim, B. T., Bagheri, N., Simpson, A., Koea, J., & Dennett, E. (2016). Identifying important comorbidity among cancer populations using administrative data: Prevalence and impact on survival. Asia-Pacific Journal of Clinical Oncology, 12(1), e47-e56. doi: 10.1111/ajco.12130

Blakely, T., Collinson, L., Kvizhinadze, G., Nair, N., Foster, R., Dennett, E., & Sarfati, D. (2015). Cancer care coordinators in stage III colon cancer: A cost-utility analysis. BMC Health Services Research, 15, 306. doi: 10.1186/s12913-015-0970-5

Dew, K., Stubbe, M., Signal, L., Stairmand, J., Dennett, E., Koea, J., Simpson, A., Sarfati, D., … Holdaway, M. (2015). Cancer care decision making in multidisciplinary meetings. Qualitative Health Research, 25(3), 397-407. doi: 10.1177/1049732314553010

Sarfati, D., Gurney, J., Stanley, J., Salmond, C., Crampton, P., Dennett, E., … Pearce, N. (2014). Cancer-specific administrative data—based comorbidity indices provided valid alternative to Charlson and National Cancer Institute Indices. Journal of Clinical Epidemiology, 67(5), 586-595. doi: 10.1016/j.jclinepi.2013.11.012

Goonerante, D., Gray, C., Lim, M., Dixon, L., Dobbs, B., Wakeman, C., Frizelle, F., for the Colorectal Lung Metastases Research Group (CRLMRG), including Thompson-Fawcett, M., Ho, C., & Dennett, E. (2013). Survival outcome in New Zealand after resection of colorectal cancer lung metastases. ANZ Journal of Surgery, 83(12), 959-962. doi: 10.1111/ans.12012

Swart, E. M., Sarfati, D., Cunningham, R., Dennett, E., Signal, V., Gurney, J., & Stanley, J. (2013). Ethnicity and rectal cancer management in New Zealand. New Zealand Medical Journal, 126(1384). Retrieved from http://www.nzma.org.nz/journal

Gurney, J., Sarfati, D., Stanley, J., Dennett, E., Johnson, C., Koea, J., Simpson, A., & Studd, R. (2013). Unstaged cancer in a population-based registry: Prevalence, predictors and patient prognosis. Cancer Epidemiology, 37(4), 498-504. doi: 10.1016/j.canep.2013.03.005

Shah, A. B., Sarfati, D., Blakely, T., Atkinson, J., & Dennett, E. R. (2012). Trends in colorectal cancer incidence rates in New Zealand, 1981-2004. ANZ Journal of Surgery, 82(4), 258-264. doi: 10.1111/j.1445-2197.2011.05995.x

Brougham, N. D. L. S., Dennett, E. R., Cameron, R., & Tan, S. T. (2012). The incidence of metastasis from cutaneous squamous cell carcinoma and the impact of its risk factors. Journal of Surgical Oncology, 106(7), 811-815. doi: 10.1002/jso.23155

Brougham, N. D. L., Dennett, E. R., & Tan, S. T. (2011). Changing incidence of non-melanoma skin cancer in New Zealand. ANZ Journal of Surgery, 81(9), 633-636. doi: 10.1111/j.1445-2197.2010.05583.x

Brougham, N. D. L., Dennett, E. R., & Tan, S. T. (2010). Non-melanoma skin cancers in New Zealand: A neglected problem. New Zealand Medical Journal, 123(1325). Retrieved from http://journal.nzma.org.nz/journal/123-1325/4421/content.pdf

Hill, S., Sarfati, D., Blakely, T., Robson, B., Purdie, G., Chen, J., Dennett, E., Cormack, D., Cunningham, R., Dew, K., … Kawachi, I. (2010). Survival disparities in indigenous and non-indigenous New Zealanders with colon cancer: The role of patient comorbidity, treatment and health service factors. Journal of Epidemiology & Community Health, 64(2), 117-123. doi: 10.1136/jech.2008.083816

Hill, S., Sarfati, D., Blakely, T., Robson, B., Purdie, G., Dennett, E., Cormack, D., Dew, K., … Kawachi, I. (2010). Ethnicity and management of colon cancer in New Zealand: Do indigenous patients get a worse deal? Cancer, 116(13), 3205-3214. doi: 10.1002/cncr.25127

Sarfati, D., Hill, S., Purdie, G., Dennett, E., & Blakely, T. (2010). How well does routine hospitalisation data capture information on comorbidity in New Zealand? New Zealand Medical Journal, 123(1310). Retrieved from http://journal.nzma.org.nz/journal/123-1310/4010/content.pdf

Harper, S. J., McEwen, A. R., & Dennett, E. R. (2010). Immunohistochemical testing for colon cancer: What do New Zealand surgeons know? New Zealand Medical Journal, 123(1325). Retrieved from http://journal.nzma.org.nz/journal/123-1325/4413/content.pdf

Rajaratnam, S. G., & Dennett, E. R. (2009). Development of metachronous neoplasms after colorectal cancer resection: Absence of synchronous neoplasms predicts a lower risk. New Zealand Medical Journal, 122(1294). Retrieved from http://journal.nzma.org.nz/journal/122-1294/3583/content.pdf

Sarfati, D., Hill, S., Blakely, T., Robson, B., Purdie, G., Dennett, E., Cormack, D., & Dew, K. (2009). The effect of comorbidity on the use of adjuvant chemotherapy and survival from colon cancer: A retrospective cohort study. BMC Cancer, 9, 116. doi: 10.1186/1471-2407-9-116

Cunningham, R., Sarfati, D., Hill, S., Dennett, E., & O'Donnell, A. (2009). Colon cancer management in New Zealand: 1996-2003. New Zealand Medical Journal, 122(1294). Retrieved from http://journal.nzma.org.nz/journal/122-1294/3581/content.pdf

Memon, S., Keating, J. P., Cooke, H. S., & Dennett, E. R. (2009). A study into external rectal anatomy: Improving patient selection for radiotherapy for rectal cancer. Diseases of the Colon & Rectum, 52(1), 87-90.

Wakeman, C. J., Dobbs, B. R., Frizelle, F. A., Bissett, I. P., Dennett, E. R., Hill, A. G., & Thompson-Fawcett, M. W. (2008). The impact of splenectomy on outcome after resection for colorectal cancer: A multicenter, nested, paired cohort study. Diseases of the Colon & Rectum, 51, 213-217. doi: 10.1007/s10350-007-9139-6

Omundsen, M. S., Dennett, E., & Walker, H. C. (2008). Patient recall after diagnostic laparoscopy for adbominal pain. ANZ Journal of Surgery, 78, 49-51. doi: 10.1111/j.1445-2197.2007.04355.x

Omundsen, M., & Dennett, E. (2006). Delay to appendicectomy and associated morbidity: A retrospective review. ANZ Journal of Surgery, 76(3), 153-155.

Carne, P. W., Frye, J. N., Kennedy-Smith, A., Keating, J., Merrie, A., Dennett, E., & Frizelle, F. A. (2004). Local invasion of the bladder with colorectal cancers: Surgical management and patterns of local recurrence. Diseases of the Colon & Rectum, 47(1), 44-47.

Merrie, A. E. M., van Rij, A. M., Dennett, E., Phillips, L. V., Yun, K., & McCall, J. L. (2003). Prognostic significance of occult metastases in colon cancer. Diseases of the Colon & Rectum, 46(2), 221-231.

Merrie, A. E. H., van Rij, A. M., Dennett, E. R., Philips, L. V., Yun, K., & McCall, J. L. (2001). Prognostic significance of occult metastases in colorectal cancer. Diseases of the Colon & Rectum, 44, 410-417.

Frizelle, F. A., Kennedy-Smith, A., Keating, J. P., Merrie, A. E. M., & Dennett, E. (2000). Outcome of patients undergoing radical surgery for colorectal cancer requiring partial or total cystectomy. Australian & New Zealand Journal of Surgery, 70(Supplement), A62.

Dennett, E., & Parry, B. R. (1999). Misconceptions about the colonic J-pouch: What the accumulating data show. Diseases of the Colon & Rectum, 42, 804-811.

Dennett, E., & Parry, B. R. (1998). Generic surgical priority criteria scoring system: The clinical reality. New Zealand Medical Journal, 111(Suppl.), 163-166.

Dennett, E., Cochrane, C. H., & Parry, B. R. (1998). Tumor implantation by circular stapler. Techniques in Coloproctology, 2(3), 138-139.

Dennett, E., Kipping, R. R., & Parry, B. R. (1998). Priority access criteria for elective cholecystectomy: A comparison of three scoring methods. New Zealand Medical Journal, 1998, 231-233.

Dennett, E. R., & Parry, B. R. (1997). Is a nasogastric tube necessary after abdominal surgery? Anaesthesia Aotearoa, 2(3), 1-3.

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Journal - Research Other

de Burlet, K. J., Ing, A. J., Larsen, P. D., & Dennett, E. R. (2018). Systematic review of diagnostic pathways for patients presenting with acute abdominal pain. International Journal for Quality in Health Care. Advance online publication. doi: 10.1093/intqhc/mzy079

Reddy, A. K., & Dennett, E. R. (2016). Cholecystocolonic fistula: A rare intraluminal cause of large bowel obstruction. BMJ Case Reports. doi: 10.1136/bcr-2016-217141

Gurney, J., Sarfati, D., Dennett, E., & Koea, J. (2013). The completeness of cancer treatment data on the national health collections. New Zealand Medical Journal, 126(1381). Retrieved from http://www.nzma.org.nz/journal

Omundsen, M. S., & Dennett, E. (2005). An unusual cause of small bowel obstruction in a 56-year-old woman. ANZ Journal of Surgery, 75(10), 923-924. doi: 10.1111/j.1445-2197.2005.03564.x

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